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Aliases for SNORA4 Gene

Subcategory (RNA class) for SNORA4 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA4 Gene

  • Small Nucleolar RNA, H/ACA Box 4 2 3 5
  • ACA4 Small Nucleolar RNA 3
  • ACA4 SnoRNA 3
  • ACA4 3

External Ids for SNORA4 Gene

Previous GeneCards Identifiers for SNORA4 Gene

  • GC03P187997
  • GC03P187999
  • GC03P186510
  • GC03P186514
  • GC03P186517
  • GC03P186520
  • GC03P186526
  • GC03P186531
  • GC03P186537
  • GC03P186546
  • GC03P186554
  • GC03P186572
  • GC03P186791
  • GC03P186797
  • GC03P186802
  • GC03P186808
  • GC03P186813
  • GC03P186818
  • GC03P186823

Summaries for SNORA4 Gene

GeneCards Summary for SNORA4 Gene

SNORA4 (Small Nucleolar RNA, H/ACA Box 4) is an RNA Gene, and is affiliated with the snoRNA class.

Additional gene information for SNORA4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA4 Gene

Genomics for SNORA4 Gene

GeneHancer (GH) Regulatory Elements for SNORA4 Gene

Promoters and enhancers for SNORA4 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I186782 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 574.8 -1.9 -1866 7.1 CLOCK FEZF1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 SP3 MEF2D SNORA4 ENSG00000200418 SNORA81 EIF4A2 ENSG00000263826 GC03P186785 GC03P186828 GC03P186831 GC03P186832 GC03P186834
GH03I186570 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 27.2 -216.9 -216916 2.3 HNRNPUL1 PKNOX1 SMAD1 MLX ARNT ARID4B NEUROD1 SIN3A DMAP1 ZNF2 TBCCD1 DNAJB11 TRA2B ENSG00000200418 SNORA4 SNORA81 RFC4 RPS20P14 SNORA63 CRYGS
GH03I187735 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 21 +954.2 954198 13 CLOCK MLX DMAP1 YY1 SLC30A9 E2F8 ZNF143 MEF2D SSRP1 ZNF610 BCL6 BCL6-AS1 LOC100131635 ENSG00000200418 SNORA4 LPP RFC4 SNORA81 ST6GAL1 RTP4
GH03I186930 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 24 +144.4 144386 4.6 HDGF FOXA2 SMAD1 ARNT ARID4B SIN3A FEZF1 DMAP1 YY1 POLR2B ST6GAL1 GC03P186932 SNORA4 RFC4 TRA2B TBCCD1 SNORA81 ADIPOQ ENSG00000200418 SNORA63
GH03I187285 Enhancer 1.4 FANTOM5 Ensembl ENCODE 19.3 +499.1 499058 1.7 FOXA2 ATF1 ETS1 YY1 TCF12 ZNF766 FOS ATF7 RXRA ZHX2 SNORA4 ENSG00000200418 TBCCD1 SNORA81 MASP1 RFC4 SNORA63 LOC101929130 LOC105374260
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the SNORA4 gene promoter:

Genomic Locations for SNORA4 Gene

Genomic Locations for SNORA4 Gene
chr3:186,787,612-186,787,749
(GRCh38/hg38)
Size:
138 bases
Orientation:
Plus strand
chr3:186,505,401-186,505,538
(GRCh37/hg19)

Genomic View for SNORA4 Gene

Genes around SNORA4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA4 Gene

Proteins for SNORA4 Gene

Post-translational modifications for SNORA4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA4 Gene

Domains & Families for SNORA4 Gene

Gene Families for SNORA4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA4 Gene

Function for SNORA4 Gene

Phenotypes From GWAS Catalog for SNORA4 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA4 Gene

Localization for SNORA4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA4 Gene

Pathways & Interactions for SNORA4 Gene

SuperPathways for SNORA4 Gene

No Data Available

Interacting Proteins for SNORA4 Gene

Gene Ontology (GO) - Biological Process for SNORA4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA4 Gene

Drugs & Compounds for SNORA4 Gene

No Compound Related Data Available

Transcripts for SNORA4 Gene

mRNA/cDNA for SNORA4 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA4 Gene

No ASD Table

Relevant External Links for SNORA4 Gene

GeneLoc Exon Structure for
SNORA4
ECgene alternative splicing isoforms for
SNORA4

Expression for SNORA4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA4 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA4 Gene:

SNORA4

SOURCE GeneReport for Unigene cluster for SNORA4 Gene:

Hs.743897
genes like me logo Genes that share expression patterns with SNORA4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA4 Gene

Orthologs for SNORA4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA4 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA4 34
  • 85 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm24616 34
  • 84 (a)
ManyToMany
Gm25588 34
  • 79 (a)
ManyToMany
Gm25582 34
  • 76 (a)
ManyToMany
Gm24460 34
  • 75 (a)
ManyToMany
Gm24728 34
  • 70 (a)
ManyToMany
Gm24500 34
  • 67 (a)
ManyToMany
Gm26495 34
  • 67 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA4 34
  • 68 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA4 34
  • 63 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA4 34
  • 64 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA4 34
  • 62 (a)
OneToMany
Species where no ortholog for SNORA4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA4 Gene

ENSEMBL:
Gene Tree for SNORA4 (if available)
TreeFam:
Gene Tree for SNORA4 (if available)

Paralogs for SNORA4 Gene

No data available for Paralogs for SNORA4 Gene

Variants for SNORA4 Gene

Sequence variations from dbSNP and Humsavar for SNORA4 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1000369195 -- 186,786,981(+) T/C/G upstream_transcript_variant
rs1000742171 -- 186,786,795(+) G/C upstream_transcript_variant
rs1002198857 -- 186,788,089(+) T/C/G downstream_transcript_variant
rs1003188684 -- 186,787,055(+) C/T upstream_transcript_variant
rs1004555557 -- 186,787,430(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA4 Gene

Variant ID Type Subtype PubMed ID
dgv5005n100 CNV gain 25217958
esv2759206 CNV loss 17122850
esv34136 CNV loss 18971310
esv3893839 CNV gain 25118596
nsv1012615 CNV gain 25217958

Additional Variant Information for SNORA4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA4 Gene

Disorders for SNORA4 Gene

Additional Disease Information for SNORA4

No disorders were found for SNORA4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA4 Gene

Publications for SNORA4 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA4 Gene

Sources for SNORA4 Gene

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