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Aliases for SNORA3B Gene

Subcategory (RNA class) for SNORA3B Gene

snoRNA

Quality Score for this RNA gene is

12.2

Aliases for SNORA3B Gene

  • Small Nucleolar RNA, H/ACA Box 3B 2 3 5
  • Small Nucleolar RNA, H/ACA Box 45B 2 3
  • Small Nucleolar RNA, H/ACA Box 45 2 3
  • ACA3-2 SnoRNA 3
  • SNORA45B 3
  • SNORA45 3
  • ACA3-2 3

External Ids for SNORA3B Gene

Previous HGNC Symbols for SNORA3B Gene

  • SNORA45
  • SNORA45B

Summaries for SNORA3B Gene

Entrez Gene Summary for SNORA3B Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA3B Gene

SNORA3B (Small Nucleolar RNA, H/ACA Box 3B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA3B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA3/SNORA45 family: The members of this family belong to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines [1]. This family includes mouse snoMBI-28 and human homologues ACA3 (SNORA3) and ACA3-2 (SNORA45). Both ACA3 and ACA3-2 share the same host gene [3]. MBI-28, ACA3 and ACA3-2 are all predicted to guide the pseudouridylation of residues in 28S rRNA [1,2,3].

View fRNAdb secondary structures for SNORA3B

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA3B Gene

Genomics for SNORA3B Gene

Genomic Location for SNORA3B Gene

Chromosome:
11
Start:
8,685,439 bp from pter
End:
8,685,569 bp from pter
Size:
131 bases
Orientation:
Plus strand

Genomic View for SNORA3B Gene

Genes around SNORA3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA3B Gene

ORGUL Member Location for SNORA3B Gene

ORGUL Member Location for SNORA3B gene

No data available for Regulatory Elements for SNORA3B Gene

Proteins for SNORA3B Gene

Post-translational modifications for SNORA3B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA3B Gene

Domains & Families for SNORA3B Gene

Gene Families for SNORA3B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA3B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA3B Gene

Function for SNORA3B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA3B Gene

Localization for SNORA3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA3B Gene

Pathways & Interactions for SNORA3B Gene

SuperPathways for SNORA3B Gene

No Data Available

Interacting Proteins for SNORA3B Gene

Gene Ontology (GO) - Biological Process for SNORA3B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA3B Gene

Drugs & Compounds for SNORA3B Gene

No Compound Related Data Available

Transcripts for SNORA3B Gene

fRNAdb Secondary structures for SNORA3B Gene

  • FR229415

mRNA/cDNA for SNORA3B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA3B Gene

No ASD Table

Relevant External Links for SNORA3B Gene

GeneLoc Exon Structure for
SNORA3B
ECgene alternative splicing isoforms for
SNORA3B

Expression for SNORA3B Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SNORA3B Gene

Orthologs for SNORA3B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA3B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SNORA3 36
  • 66 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia SNORA3 36
  • 88 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA3 36
  • 75 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm25539 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA3 36
  • 73 (a)
ManyToMany
SNORA3 36
  • 73 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia SNORA3 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA3 36
  • 64 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA3 36
  • 69 (a)
ManyToMany
SNORA3 36
  • 68 (a)
ManyToMany
SNORA3 36
  • 62 (a)
ManyToMany
SNORA3 36
  • 70 (a)
ManyToMany
Species with no ortholog for SNORA3B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA3B Gene

ENSEMBL:
Gene Tree for SNORA3B (if available)
TreeFam:
Gene Tree for SNORA3B (if available)

Paralogs for SNORA3B Gene

No data available for Paralogs for SNORA3B Gene

Variants for SNORA3B Gene

Relevant External Links for SNORA3B Gene

HapMap Linkage Disequilibrium report
SNORA3B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNORA3B Gene

Disorders for SNORA3B Gene

Relevant External Links for SNORA3B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA3B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA3B

No disorders were found for SNORA3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA3B Gene

Publications for SNORA3B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 1 2 3 67
  2. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu A.D. … Qu L.H. (Nucleic Acids Res. 2005) 1 2 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) . … Gojobori T. (Nucleic Acids Res. 2008) 1

Products for SNORA3B Gene

Sources for SNORA3B Gene

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