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Aliases for SNORA3B Gene

Subcategory (RNA class) for SNORA3B Gene


Quality Score for this RNA gene is


Aliases for SNORA3B Gene

  • Small Nucleolar RNA, H/ACA Box 3B 2 3 5
  • Small Nucleolar RNA, H/ACA Box 45B 2 3
  • Small Nucleolar RNA, H/ACA Box 45 2 3
  • ACA3-2 SnoRNA 3
  • SNORA45B 3
  • SNORA45 3
  • ACA3-2 3

External Ids for SNORA3B Gene

Previous HGNC Symbols for SNORA3B Gene

  • SNORA45
  • SNORA45B

Previous GeneCards Identifiers for SNORA3B Gene

  • GC11P008696
  • GC11P008701
  • GC11P008708
  • GC11P008711

Summaries for SNORA3B Gene

Entrez Gene Summary for SNORA3B Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA45, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA3B Gene

SNORA3B (Small Nucleolar RNA, H/ACA Box 3B) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA3B Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • Small nucleolar RNA SNORA3/SNORA45 family: The members of this family belong to the H/ACA class of snoRNAs which are thought to guide the sites of modification of uridines to pseudouridines [1]. This family includes mouse snoMBI-28 and human homologues ACA3 (SNORA3) and ACA3-2 (SNORA45). Both ACA3 and ACA3-2 share the same host gene [3]. MBI-28, ACA3 and ACA3-2 are all predicted to guide the pseudouridylation of residues in 28S rRNA [1,2,3].

View fRNAdb secondary structures for SNORA3B

Additional gene information for SNORA3B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA3B Gene

Genomics for SNORA3B Gene

Regulatory Elements for SNORA3B Gene

Enhancers for SNORA3B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H008681 1.7 Ensembl ENCODE dbSUPER 36.8 +0.4 417 8.7 HNRNPUL1 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 TRIM66 SNORA3B EIF3F ZNF143 RPL21P97 RPL27A STK33 WEE1 RPL23AP65 ENSG00000254665
GH11H009458 1.4 ENCODE dbSUPER 26.5 +776.0 775960 5 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 SNORA3B RPL27A RPL21P97 TMEM9B-AS1 WEE1 TRIM66 IPO7 LOC644656 PIR40365
GH11H009218 1.2 Ensembl ENCODE dbSUPER 19 +534.0 534009 1.8 JUN MAX CEBPB ZNF266 EP300 RFX5 PRDM6 JUND ZNF624 STAT3 SNORA3B DENND5A SCUBE2 RPL27A ZNF143 RPL21P97 TMEM41B GC11M009222
GH11H009551 1.5 Ensembl ENCODE dbSUPER 14.5 +866.8 866824 1.8 HDGF PKNOX1 ATF1 ARNT TCF12 ZNF766 GATA2 ELK1 ATF7 ZC3H11A SNORA3B WEE1 ENSG00000238387 RPL27A RPL21P97 AKIP1 ZNF143 PIR40365 LOC644656
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA3B on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA3B Gene

Genomic Locations for SNORA3B Gene
131 bases
Plus strand

Genomic View for SNORA3B Gene

Genes around SNORA3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA3B Gene

ORGUL Member Location for SNORA3B Gene

ORGUL Member Location for SNORA3B gene

Proteins for SNORA3B Gene

Post-translational modifications for SNORA3B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA3B Gene

Domains & Families for SNORA3B Gene

Gene Families for SNORA3B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA3B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA3B Gene

Function for SNORA3B Gene

Phenotypes From GWAS Catalog for SNORA3B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA3B Gene

Localization for SNORA3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA3B Gene

Pathways & Interactions for SNORA3B Gene

SuperPathways for SNORA3B Gene

No Data Available

Interacting Proteins for SNORA3B Gene

Gene Ontology (GO) - Biological Process for SNORA3B Gene


No data available for Pathways by source and SIGNOR curated interactions for SNORA3B Gene

Drugs & Compounds for SNORA3B Gene

No Compound Related Data Available

Transcripts for SNORA3B Gene

fRNAdb Secondary structures for SNORA3B Gene

  • FR229415

mRNA/cDNA for SNORA3B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA3B Gene

No ASD Table

Relevant External Links for SNORA3B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA3B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA3B Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA3B Gene

Orthologs for SNORA3B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA3B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia SNORA3 34
  • 100 (a)
(Canis familiaris)
Mammalia SNORA3 34
  • 88 (a)
(Monodelphis domestica)
Mammalia SNORA3 34
  • 75 (a)
(Mus musculus)
Mammalia Gm25539 34
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA3 34 34
  • 73 (a)
(Bos Taurus)
Mammalia SNORA3 34
  • 66 (a)
(Gallus gallus)
Aves SNORA3 34
  • 64 (a)
(Danio rerio)
Actinopterygii SNORA3 34 34 34 34
  • 69 (a)
Species where no ortholog for SNORA3B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA3B Gene

Gene Tree for SNORA3B (if available)
Gene Tree for SNORA3B (if available)

Paralogs for SNORA3B Gene

No data available for Paralogs for SNORA3B Gene

Variants for SNORA3B Gene

Sequence variations from dbSNP and Humsavar for SNORA3B Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001394543 -- 8,684,284(+) TCCTC(A/G)AAGAG intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1002378478 -- 8,685,051(+) TAGCA(C/G)TGCCT intron-variant, upstream-variant-2KB
rs1003447583 -- 8,685,994(+) CAGAC(A/G)TTGGC downstream-variant-500B, utr-variant-3-prime
rs1003957078 -- 8,683,743(+) CGAAA(C/T)CTCGG intron-variant, upstream-variant-2KB
rs1004506457 -- 8,685,356(+) TGTCC(A/G)TTGAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA3B Gene

Variant ID Type Subtype PubMed ID
nsv499766 OTHER inversion 21111241
nsv7215 OTHER inversion 18451855
nsv975880 CNV duplication 23825009

Relevant External Links for SNORA3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA3B Gene

Disorders for SNORA3B Gene

Relevant External Links for SNORA3B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SNORA3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA3B Gene

Publications for SNORA3B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 60
  2. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu AD … Qu LH (Nucleic acids research 2005) 1 2 3 60
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A … Hentze MW (Cell 2012) 3 60
  4. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 60
  5. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1

Products for SNORA3B Gene

Sources for SNORA3B Gene

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