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Aliases for SNORA30 Gene

Subcategory (RNA class) for SNORA30 Gene

snoRNA

Quality Score for this RNA gene is

11.2

Aliases for SNORA30 Gene

  • Small Nucleolar RNA, H/ACA Box 30 2 3
  • ACA30 SnoRNA 3
  • ACA30 3

External Ids for SNORA30 Gene

Summaries for SNORA30 Gene

GeneCards Summary for SNORA30 Gene

SNORA30 (Small Nucleolar RNA, H/ACA Box 30) is a RNA Gene, and belongs to snoRNA RNA class.

fRNAdb sequence ontologies for SNORA30 Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA30/SNORA37 family: The members of this family belong to the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines [1]. This family includes human ACA30 (SNORA30), ACA37 (SNORA37) and the mouse homolog MBI-26 [1,2]. Both ACA37 and ACA30 are predicted to guide the pseudouridylation of residue U4643 of 28S rRNA [3].

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA30 Gene

Genomics for SNORA30 Gene

Genomic Location for SNORA30 Gene

Start:
30,710,537 bp from pter
End:
30,710,665 bp from pter
Size:
129 bases
Orientation:
Plus strand

Genomic View for SNORA30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA30 Gene

Regulatory Elements for SNORA30 Gene

ORGUL Member Location for SNORA30 Gene

ORGUL Member Location for SNORA30 gene

Proteins for SNORA30 Gene

Post-translational modifications for SNORA30 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA30 Gene

Domains for SNORA30 Gene

Gene Families for SNORA30 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing
genes like me logo Genes that share domains with SNORA30: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for SNORA30 Gene

Function for SNORA30 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA30 Gene

Localization for SNORA30 Gene

No data available for Gene Ontology (GO) - Cellular Components for SNORA30 Gene

Pathways for SNORA30 Gene

SuperPathways for SNORA30 Gene

No Data Available

Interacting Proteins for SNORA30 Gene

Gene Ontology (GO) - Biological Process for SNORA30 Gene

None

No data available for Pathways by source for SNORA30 Gene

Transcripts for SNORA30 Gene

mRNA/cDNA for SNORA30 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA30 Gene

No ASD Table

Relevant External Links for SNORA30 Gene

GeneLoc Exon Structure for
SNORA30
ECgene alternative splicing isoforms for
SNORA30

Expression for SNORA30 Gene

mRNA expression in normal human tissues for SNORA30 Gene

SOURCE GeneReport for Unigene cluster for SNORA30 Gene Hs.689718

genes like me logo Genes that share expressions with SNORA30: view

Orthologs for SNORA30 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA30 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA30 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA30 37
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA30 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora30 16
Snora30 37
  • 85 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA30 37
  • 74 (a)
OneToMany
SNORA30 37
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA30 37
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA30 37
  • 53 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA30 37
  • 47 (a)
ManyToMany
SNORA30 37
  • 53 (a)
ManyToMany
SNORA30 37
  • 54 (a)
ManyToMany
SNORA30 37
  • 53 (a)
ManyToMany
Species with no ortholog for SNORA30:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA30 Gene

ENSEMBL:
Gene Tree for SNORA30 (if available)
TreeFam:
Gene Tree for SNORA30 (if available)

Paralogs for SNORA30 Gene

No data available for Paralogs for SNORA30 Gene

Variants for SNORA30 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA30 Gene

Variant ID Type Subtype PubMed ID
nsv469724 CNV Loss 16826518
nsv833188 CNV Loss 17160897
nsv905728 CNV Loss 21882294
nsv905729 CNV Loss 21882294

Relevant External Links for SNORA30 Gene

HapMap Linkage Disequilibrium report
SNORA30

No data available for Sequence variations from dbSNP and Humsavar for SNORA30 Gene

Disorders for SNORA30 Gene

No disorders were found for SNORA30 Gene.

No data available for UniProtKB/Swiss-Prot for SNORA30 Gene

Publications for SNORA30 Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for SNORA30 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA30
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA30
    • Block miRNA regulation of SNORA30 using miScript Target Protectors

    Sources for SNORA30 Gene

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