Subcategory (RNA class) for SNORA30 Gene
Quality Score for this RNA gene is
ORGUL Members for SNORA30 Gene
Previous GeneCards Identifiers for SNORA30 Gene
GeneCards Summary for SNORA30 Gene
SNORA30 (Small Nucleolar RNA, H/ACA Box 30) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORA30 Gene - the ORGUL cluster for this gene includes several descriptions:
nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.
H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.
Small nucleolar RNA SNORA30/SNORA37 family: The members of this family belong to the H/ACA class of snoRNAs that guide the sites of modification of uridines to pseudouridines . This family includes human ACA30 (SNORA30), ACA37 (SNORA37) and the mouse homolog MBI-26 [1,2]. Both ACA37 and ACA30 are predicted to guide the pseudouridylation of residue U4643 of 28S rRNA .