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Aliases for SNORA2C Gene

Subcategory (RNA class) for SNORA2C Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA2C Gene

  • Small Nucleolar RNA, H/ACA Box 2C 2 3 5
  • Small Nucleolar RNA, H/ACA Box 34 2 3
  • ACA34 SnoRNA 3
  • MIR1291 3
  • SNORA34 3
  • ACA34 3

External Ids for SNORA2C Gene

Previous HGNC Symbols for SNORA2C Gene

  • SNORA34

Previous GeneCards Identifiers for SNORA2C Gene

  • GC12M048660
  • GC12M048661
  • GC12M048662
  • GC12M048663
  • GC12M048664

Summaries for SNORA2C Gene

GeneCards Summary for SNORA2C Gene

SNORA2C (Small Nucleolar RNA, H/ACA Box 2C) is an RNA Gene, and is affiliated with the snoRNA class. Diseases associated with SNORA2C include Wilson-Turner X-Linked Mental Retardation Syndrome.

Additional gene information for SNORA2C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA2C Gene

Genomics for SNORA2C Gene

GeneHancer (GH) Regulatory Elements for SNORA2C Gene

Promoters and enhancers for SNORA2C Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12I048600 Enhancer 0.9 Ensembl ENCODE 10.7 +53.3 53317 1.2 PKNOX1 JUN BACH1 EBF1 BATF RELA FOSL1 CTBP1 ZNF766 ZNF316 LALBA SNORA2C CCDC184 ASB8 TUBA1C OR11M1P GC12M048339
GH12I048618 Enhancer 0.7 ENCODE 10.2 +35.9 35885 0.2 CTCF RB1 BMI1 IRF4 RAD21 RELA CC2D1A ARID2 SMC3 ZNF143 SNORA2C ASB8 CCDC184 RNU6-1203P OR11M1P LALBA GC12M048339
GH12I048686 Enhancer 0.6 ENCODE 10.7 -32.3 -32315 0.2 NFATC3 TAL1 CBFA2T3 ZNF121 TCF12 SKIL NCOR1 HDAC2 POLR2A MYNN GC12M048339 SNORA2C KANSL2
GH12I047837 Enhancer 1.2 Ensembl ENCODE dbSUPER 4.6 +816.2 816214 1.4 RB1 RAD21 RFX5 ZEB1 ZNF213 ARID2 ZNF207 ZNF143 RCOR1 IKZF2 SNORA2C HDAC7 LINC02354 ENSG00000205537
GH12I048690 Enhancer 0.3 ENCODE 10.1 -36.2 -36184 1.4 ATF2 GC12M048689 KANSL2 SNORA2C GC12M048339 CCNT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around SNORA2C on UCSC Golden Path with GeneCards custom track

Genomic Locations for SNORA2C Gene

Genomic Locations for SNORA2C Gene
chr12:48,654,382-48,654,518
(GRCh38/hg38)
Size:
137 bases
Orientation:
Minus strand
chr12:49,048,165-49,048,301
(GRCh37/hg19)

Genomic View for SNORA2C Gene

Genes around SNORA2C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA2C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA2C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA2C Gene

Proteins for SNORA2C Gene

Post-translational modifications for SNORA2C Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA2C Gene

Domains & Families for SNORA2C Gene

Gene Families for SNORA2C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA2C: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA2C Gene

Function for SNORA2C Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA2C Gene

Localization for SNORA2C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SNORA2C gene
Compartment Confidence
cytosol 2
plasma membrane 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA2C Gene

Pathways & Interactions for SNORA2C Gene

SuperPathways for SNORA2C Gene

No Data Available

Interacting Proteins for SNORA2C Gene

Gene Ontology (GO) - Biological Process for SNORA2C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA2C Gene

Drugs & Compounds for SNORA2C Gene

No Compound Related Data Available

Transcripts for SNORA2C Gene

mRNA/cDNA for SNORA2C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA2C Gene

No ASD Table

Relevant External Links for SNORA2C Gene

GeneLoc Exon Structure for
SNORA2C
ECgene alternative splicing isoforms for
SNORA2C

Expression for SNORA2C Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA2C Gene:

SNORA2C
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA2C Gene

Orthologs for SNORA2C Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA2C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA2 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA2 34
  • 88 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA2 34
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora34 34
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA2 34
  • 66 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA2 34
  • 60 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA2 34
  • 68 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA2 34
  • 61 (a)
OneToMany
Species where no ortholog for SNORA2C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA2C Gene

ENSEMBL:
Gene Tree for SNORA2C (if available)
TreeFam:
Gene Tree for SNORA2C (if available)

Paralogs for SNORA2C Gene

No data available for Paralogs for SNORA2C Gene

Variants for SNORA2C Gene

Sequence variations from dbSNP and Humsavar for SNORA2C Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1001115628 -- 48,654,762(-) A/G upstream_transcript_variant
rs1001146712 -- 48,654,427(-) G/A/C non_coding_transcript_variant
rs1001624913 -- 48,656,476(-) T/C upstream_transcript_variant
rs1002081898 -- 48,656,143(-) C/A upstream_transcript_variant
rs1002155624 -- 48,655,853(-) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for SNORA2C Gene

Variant ID Type Subtype PubMed ID
dgv1496n100 CNV gain 25217958

Additional Variant Information for SNORA2C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA2C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA2C Gene

Disorders for SNORA2C Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNORA2C Gene - From: DISEASES

Disorder Aliases PubMed IDs
wilson-turner x-linked mental retardation syndrome
  • wts
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with SNORA2C: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SNORA2C Gene

Publications for SNORA2C Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 2 3 58
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 2 3 58
  3. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein JI … Sullivan PF (Nature communications 2014) 3 58
  4. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 58
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58

Products for SNORA2C Gene

Sources for SNORA2C Gene

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