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Aliases for SNORA25 Gene

Subcategory (RNA class) for SNORA25 Gene

snoRNA

Quality Score for this RNA gene is

22

Aliases for SNORA25 Gene

  • Small Nucleolar RNA, H/ACA Box 25 2 3 5
  • SNORA25A 3
  • ACA25 3

External Ids for SNORA25 Gene

Previous GeneCards Identifiers for SNORA25 Gene

  • GC11M093132
  • GC11U901200
  • GC11M093174
  • GC11M093184
  • GC11M093463

Summaries for SNORA25 Gene

GeneCards Summary for SNORA25 Gene

SNORA25 (Small Nucleolar RNA, H/ACA Box 25) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA25 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA25: ACA25 is a member of the H/ACA class of snoRNA that guide the sites of modification of uridines to pseudouridines [1].

View fRNAdb secondary structures for SNORA25

Additional gene information for SNORA25 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA25 Gene

Genomics for SNORA25 Gene

Regulatory Elements for SNORA25 Gene

Enhancers for SNORA25 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H093783 1.1 ENCODE 11.3 -54.1 -54085 2 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS ZNF548 C11orf54 SNORA1 MED17 MRE11 ANKRD49 ENSG00000255233 LOC642791 ENSG00000254874 ENSG00000233536 SNORA40
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA25 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNORA25 Gene

Chromosome:
11
Start:
93,730,513 bp from pter
End:
93,730,646 bp from pter
Size:
134 bases
Orientation:
Minus strand

Genomic View for SNORA25 Gene

Genes around SNORA25 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA25 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA25 Gene

ORGUL Member Location for SNORA25 Gene

ORGUL Member Location for SNORA25 gene

Proteins for SNORA25 Gene

Post-translational modifications for SNORA25 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA25 Gene

Domains & Families for SNORA25 Gene

Gene Families for SNORA25 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA25: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA25 Gene

Function for SNORA25 Gene

Animal Model Products

CRISPR Products

miRNA for SNORA25 Gene

miRTarBase miRNAs that target SNORA25

Clone Products

  • Applied Biological Materials Clones for SNORA25
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SNORA25 Gene

Localization for SNORA25 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA25 Gene

Pathways & Interactions for SNORA25 Gene

SuperPathways for SNORA25 Gene

No Data Available

Interacting Proteins for SNORA25 Gene

Gene Ontology (GO) - Biological Process for SNORA25 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA25 Gene

Drugs & Compounds for SNORA25 Gene

No Compound Related Data Available

Transcripts for SNORA25 Gene

fRNAdb Secondary structures for SNORA25 Gene

  • RF00402;SNORA25;ADDF010742113.1/30-159

mRNA/cDNA for SNORA25 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for SNORA25
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA25 Gene

No ASD Table

Relevant External Links for SNORA25 Gene

GeneLoc Exon Structure for
SNORA25
ECgene alternative splicing isoforms for
SNORA25

Expression for SNORA25 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA25 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA25 Gene:

SNORA25

SOURCE GeneReport for Unigene cluster for SNORA25 Gene:

Hs.738736
genes like me logo Genes that share expression patterns with SNORA25: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA25 Gene

Orthologs for SNORA25 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA25 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA25 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA25 34 34
  • 82 (a)
OneToMany
cow
(Bos Taurus)
Mammalia SNORA25 34
  • 79 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm22579 34
  • 75 (a)
OneToMany
Gm24539 34
  • 75 (a)
OneToMany
Gm22743 34
  • 74 (a)
OneToMany
Gm24095 34
  • 74 (a)
OneToMany
Gm22765 34
  • 67 (a)
OneToMany
Gm24945 34
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SNORA25 34
  • 69 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA25 34 34
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves SNORA25 34
  • 64 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA25 34
  • 65 (a)
OneToMany
Species where no ortholog for SNORA25 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA25 Gene

ENSEMBL:
Gene Tree for SNORA25 (if available)
TreeFam:
Gene Tree for SNORA25 (if available)

Paralogs for SNORA25 Gene

No data available for Paralogs for SNORA25 Gene

Variants for SNORA25 Gene

Sequence variations from dbSNP and Humsavar for SNORA25 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001122861 -- 93,731,096(+) TAATG(A/G)CCATT nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs1001194844 -- 93,730,827(+) GCTTG(A/G)TTATT downstream-variant-500B, upstream-variant-2KB
rs1001392515 -- 93,730,547(+) CAAAC(A/G)TTAGG nc-transcript-variant, downstream-variant-500B
rs1002539698 -- 93,730,250(+) ACTTC(A/G)AGCCA downstream-variant-500B, reference, synonymous-codon, missense
rs1002861927 -- 93,732,336(+) AAACT(A/G)AACAC downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA25 Gene

Variant ID Type Subtype PubMed ID
esv3627294 CNV gain 21293372
nsv832232 CNV gain 17160897

Relevant External Links for SNORA25 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA25

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA25 Gene

Disorders for SNORA25 Gene

Relevant External Links for SNORA25

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA25

No disorders were found for SNORA25 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA25 Gene

Publications for SNORA25 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 60
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss AM … Kiss T (Molecular and cellular biology 2004) 1 2 3 60
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 60
  4. The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1
  5. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1

Products for SNORA25 Gene

Sources for SNORA25 Gene

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