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Aliases for SNORA21 Gene

Subcategory (RNA class) for SNORA21 Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA21 Gene

  • Small Nucleolar RNA, H/ACA Box 21 2 3 5
  • ACA21 Small Nucleolar RNA 3
  • ACA21 SnoRNA 3
  • ACA21 3

External Ids for SNORA21 Gene

Previous GeneCards Identifiers for SNORA21 Gene

  • GC17M034266
  • GC17M037010
  • GC17M032804
  • GC17M037015
  • GC17M037024
  • GC17M037027

Summaries for SNORA21 Gene

GeneCards Summary for SNORA21 Gene

SNORA21 (Small Nucleolar RNA, H/ACA Box 21) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA21 Gene

Genomics for SNORA21 Gene

Regulatory Elements for SNORA21 Gene

Enhancers for SNORA21 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G038867 1.8 FANTOM5 ENCODE dbSUPER 25.7 -18.7 -18709 9.2 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 ENSG00000266469 MED1 CDK12 ENSG00000275665 SNORA21 ENSG00000275532 CWC25 PSMB3 ENSG00000252699 C17orf98
GH17G038584 1.5 Ensembl ENCODE dbSUPER 30.3 +268.0 267982 1.7 ATF1 ZNF493 ARID4B GLI4 DMAP1 ZNF2 ZNF48 ZNF121 GLIS2 ZNF143 MED1 ENSG00000266469 RPL23 SNORA21 ENSG00000275532 CDK12 RPL19 ENSG00000274996 LOC105371761
GH17G039191 1.4 ENCODE dbSUPER 28 -344.0 -344003 11.7 CREB3L1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 TBX21 ZNF610 GLIS1 ENSG00000266469 CDK12 SNORA21 MSL1 MED1 SNORD124 PGAP3 ENSG00000275665 RPL19 STAC2
GH17G038745 1.5 ENCODE dbSUPER 25.4 +103.2 103222 8.6 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 ENSG00000266469 MED1 CDK12 PCGF2 ENSG00000275532 ENSG00000275665 SNORA21 CISD3 RPL19 RPL23
GH17G038920 1.4 Ensembl ENCODE dbSUPER 23.7 -69.2 -69231 3.1 TBP ZFP64 PAF1 ZNF202 ZNF654 CEBPB ZNF426 REST ZNF623 ZNF518A MED1 ENSG00000266469 CDK12 SNORA21 ENSG00000275532 LOC100287808 RPL23 FBXO47 C17orf98 ENSG00000275665
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA21 on UCSC Golden Path with GeneCards custom track

Promoters for SNORA21 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000093824 -305 2201 MLX CREB3L1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC

Genomic Location for SNORA21 Gene

Chromosome:
17
Start:
38,852,863 bp from pter
End:
38,852,995 bp from pter
Size:
133 bases
Orientation:
Minus strand

Genomic View for SNORA21 Gene

Genes around SNORA21 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA21 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA21 Gene

Proteins for SNORA21 Gene

Post-translational modifications for SNORA21 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA21 Gene

Domains & Families for SNORA21 Gene

Gene Families for SNORA21 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA21: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA21 Gene

Function for SNORA21 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA21 Gene

Localization for SNORA21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA21 Gene

Pathways & Interactions for SNORA21 Gene

SuperPathways for SNORA21 Gene

No Data Available

Interacting Proteins for SNORA21 Gene

Gene Ontology (GO) - Biological Process for SNORA21 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA21 Gene

Drugs & Compounds for SNORA21 Gene

No Compound Related Data Available

Transcripts for SNORA21 Gene

mRNA/cDNA for SNORA21 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA21 Gene

No ASD Table

Relevant External Links for SNORA21 Gene

GeneLoc Exon Structure for
SNORA21
ECgene alternative splicing isoforms for
SNORA21

Expression for SNORA21 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNORA21 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA21 Gene:

SNORA21

SOURCE GeneReport for Unigene cluster for SNORA21 Gene:

Hs.738742
genes like me logo Genes that share expression patterns with SNORA21: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA21 Gene

Orthologs for SNORA21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA21 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA21 35
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SNORA21 35
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SNORA21 35
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Snora21 35
  • 85 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA21 35
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA21 35
  • 71 (a)
OneToOne
chicken
(Gallus gallus)
Aves SNORA21 35
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SNORA21 35 35
  • 71 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA21 35 35
  • 60 (a)
OneToMany
Species where no ortholog for SNORA21 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA21 Gene

ENSEMBL:
Gene Tree for SNORA21 (if available)
TreeFam:
Gene Tree for SNORA21 (if available)

Paralogs for SNORA21 Gene

No data available for Paralogs for SNORA21 Gene

Variants for SNORA21 Gene

Sequence variations from dbSNP and Humsavar for SNORA21 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000125424 -- 38,854,507(+) CCTTG(C/G)TCCCT upstream-variant-2KB
rs1000500603 -- 38,854,655(+) CAGCA(G/T)GTTCT upstream-variant-2KB
rs1004881934 -- 38,852,736(+) TCCTA(A/C)AAAAG intron-variant, downstream-variant-500B
rs1004963868 -- 38,852,461(+) CAATA(C/T)GAGCA intron-variant, downstream-variant-500B
rs1005967110 -- 38,853,540(+) GCCAC(C/T)TTCGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SNORA21 Gene

Variant ID Type Subtype PubMed ID
nsv1146669 OTHER inversion 26484159
nsv833439 CNV loss 17160897

Relevant External Links for SNORA21 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA21

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA21 Gene

Disorders for SNORA21 Gene

Relevant External Links for SNORA21

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA21

No disorders were found for SNORA21 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA21 Gene

Publications for SNORA21 Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3 64
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3 64
  3. Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts. (PMID: 9047361) Ofengand J. … Bakin A. (J. Mol. Biol. 1997) 2 3 64
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64
  5. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORA21 Gene

Sources for SNORA21 Gene

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