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Aliases for SNORA17 Gene

Subcategory (RNA class) for SNORA17 Gene

snoRNA

Quality Score for this RNA gene is

11

Aliases for SNORA17 Gene

  • Small Nucleolar RNA, H/ACA Box 17 2 3
  • ACA17 SnoRNA 3
  • ACA17 3

External Ids for SNORA17 Gene

Summaries for SNORA17 Gene

GeneCards Summary for SNORA17 Gene

SNORA17 (Small Nucleolar RNA, H/ACA Box 17) is an RNA Gene, and belongs to the snoRNA class.

fRNAdb sequence ontologies for SNORA17 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA17: snoRNA ACA 17 belongs to the H/ACA family of snoRNAs and is predicted to guide pseudouridylation of the 28S rRNA at positions U4659 and U4598. It shares the same host gene together with ACA43. NB This family has a high threshold value to exclude a large number of closely related sequences that do not appear to have conserved H and ACA boxes, and may be pseudogenes.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA17 Gene

Genomics for SNORA17 Gene

Genomic Location for SNORA17 Gene

Start:
136,726,747 bp from pter
End:
136,726,879 bp from pter
Size:
133 bases
Orientation:
Minus strand

Genomic View for SNORA17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA17 Gene

Regulatory Elements for SNORA17 Gene

ORGUL Member Location for SNORA17 Gene

ORGUL Member Location for SNORA17 gene

Proteins for SNORA17 Gene

Post-translational modifications for SNORA17 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA17 Gene

Domains for SNORA17 Gene

Gene Families for SNORA17 Gene

HGNC:
  • SNORD :ncRNAs / Small nucleolar RNAs : C/D box containing

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA17: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA17 Gene

Function for SNORA17 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SNORA17 Gene

Localization for SNORA17 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA17 Gene

Pathways for SNORA17 Gene

SuperPathways for SNORA17 Gene

No Data Available

Interacting Proteins for SNORA17 Gene

Gene Ontology (GO) - Biological Process for SNORA17 Gene

None

No data available for Pathways by source for SNORA17 Gene

Transcripts for SNORA17 Gene

mRNA/cDNA for SNORA17 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA17 Gene

No ASD Table

Relevant External Links for SNORA17 Gene

GeneLoc Exon Structure for
SNORA17
ECgene alternative splicing isoforms for
SNORA17

Expression for SNORA17 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SNORA17 Gene

Orthologs for SNORA17 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for SNORA17 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Snora17 16
Species with no ortholog for SNORA17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA17 Gene

ENSEMBL:
Gene Tree for SNORA17 (if available)
TreeFam:
Gene Tree for SNORA17 (if available)

Paralogs for SNORA17 Gene

No data available for Paralogs for SNORA17 Gene

Variants for SNORA17 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA17 Gene

Variant ID Type Subtype PubMed ID
dgv8385n71 CNV Loss 21882294
dgv2426e1 CNV Complex 17122850
nsv469918 CNV Loss 18288195
dgv8400n71 CNV Loss 21882294
nsv894386 CNV Loss 21882294
nsv894387 CNV Gain 21882294
nsv8579 CNV Gain 18304495
dgv8404n71 CNV Loss 21882294
dgv2427e1 CNV Complex 17122850
esv2422220 CNV Deletion 17116639
dgv8408n71 CNV Loss 21882294
dgv8410n71 CNV Loss 21882294
dgv8411n71 CNV Loss 21882294
dgv8412n71 CNV Loss 21882294
nsv894447 CNV Loss 21882294
dgv8413n71 CNV Loss 21882294
dgv8414n71 CNV Loss 21882294
dgv8415n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv6769 CNV Insertion 18451855

Relevant External Links for SNORA17 Gene

HapMap Linkage Disequilibrium report
SNORA17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for SNORA17 Gene

Disorders for SNORA17 Gene

No disorders were found for SNORA17 Gene.

No data available for UniProtKB/Swiss-Prot for SNORA17 Gene

Publications for SNORA17 Gene

  1. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for SNORA17 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SNORA17
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SNORA17
    • Block miRNA regulation of SNORA17 using miScript Target Protectors

    Sources for SNORA17 Gene

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