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Aliases for SNORA14B Gene

Subcategory (RNA class) for SNORA14B Gene

snoRNA

Quality Score for this RNA gene is

3

Aliases for SNORA14B Gene

  • Small Nucleolar RNA, H/ACA Box 14B 2 3 5
  • ACA14b SnoRNA 3
  • ACA14b 3

External Ids for SNORA14B Gene

Previous GeneCards Identifiers for SNORA14B Gene

  • GC01M233357
  • GC01M235291
  • GC01M205739

Summaries for SNORA14B Gene

Entrez Gene Summary for SNORA14B Gene

  • Small nucleolar RNAs (snoRNAs) are 60-150 nt long non-coding RNAs, and include two groups: C/D box snoRNAs and H/ACA box snoRNAs. The C/D box snoRNAs are guides for the 2'-O-ribose methylation of rRNAs or snRNAs. The H/ACA box snoRNAs are guides for the isomerization of uridine residues into pseudouridine. This gene belongs to the group of the H/ACA box snoRNAs, and functions in 18S rRNA pseudouridylation at position U966. The gene duplication generates a 91% identical copy on chromosome 7. [provided by RefSeq, Oct 2008]

GeneCards Summary for SNORA14B Gene

SNORA14B (Small Nucleolar RNA, H/ACA Box 14B) is an RNA Gene, and is affiliated with the snoRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNORA14B Gene

Genomics for SNORA14B Gene

Regulatory Elements for SNORA14B Gene

Enhancers for SNORA14B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F235103 1.4 FANTOM5 ENCODE 12.2 +23.1 23081 2.1 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 CBX5 ZNF143 KLF13 ZNF263 MXD4 RPS21P1 SNORA14B TOMM20 ENSG00000273416 GC01P235107
GH01F234486 1.5 FANTOM5 Ensembl ENCODE 10 +639.7 639677 2.7 MLX ARID4B ZNF2 ZNF121 FOS JUNB MIER2 REST PPARG KAT8 ENSG00000228830 IRF2BP2 ENSG00000212144 GGPS1 TOMM20 SNORA14B TARBP1 LOC101927765 GC01P234531
GH01F235090 1.2 Ensembl ENCODE 11.5 +37.2 37163 1.5 ATF1 PKNOX1 ARID4B YY1 GATA2 ZNF143 ZNF263 REST SMARCA4 GLIS1 IRF2BP2 TOMM20 ENSG00000228830 SNORA14B TARBP1 TBCE ENSG00000212144 GGPS1 ENSG00000233018 LINC01348
GH01F235092 1.1 Ensembl ENCODE 11.5 +34.3 34291 1.5 ELF3 TBL1XR1 ZFP64 RAD21 ZNF143 CREM ZNF362 ZNF654 CBFB ZEB2 ENSG00000228830 IRF2BP2 SNORA14B TOMM20 TARBP1 ENSG00000212144 ENSG00000233018 LINC01348
GH01F235100 0.8 ENCODE 12.2 +27.3 27334 0.2 PKNOX1 TFAP4 MXI1 SAP130 MLX ARID4B BMI1 RARA TEAD3 FOXK2 RPS21P1 SNORA14B TOMM20 ENSG00000273416 ENSG00000233018
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNORA14B on UCSC Golden Path with GeneCards custom track

Promoters for SNORA14B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000168824 -64 2800 HDGF PKNOX1 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1

Genomic Location for SNORA14B Gene

Chromosome:
1
Start:
235,127,803 bp from pter
End:
235,127,937 bp from pter
Size:
135 bases
Orientation:
Minus strand

Genomic View for SNORA14B Gene

Genes around SNORA14B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNORA14B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNORA14B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA14B Gene

Proteins for SNORA14B Gene

Post-translational modifications for SNORA14B Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA14B Gene

Domains & Families for SNORA14B Gene

Gene Families for SNORA14B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA14B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA14B Gene

Function for SNORA14B Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA14B Gene

Localization for SNORA14B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA14B Gene

Pathways & Interactions for SNORA14B Gene

SuperPathways for SNORA14B Gene

No Data Available

Interacting Proteins for SNORA14B Gene

Gene Ontology (GO) - Biological Process for SNORA14B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNORA14B Gene

Transcripts for SNORA14B Gene

mRNA/cDNA for SNORA14B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA14B Gene

No ASD Table

Relevant External Links for SNORA14B Gene

GeneLoc Exon Structure for
SNORA14B
ECgene alternative splicing isoforms for
SNORA14B

Expression for SNORA14B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for SNORA14B Gene

NURSA nuclear receptor signaling pathways regulating expression of SNORA14B Gene:

SNORA14B

SOURCE GeneReport for Unigene cluster for SNORA14B Gene:

Hs.744743
genes like me logo Genes that share expression patterns with SNORA14B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SNORA14B Gene

Orthologs for SNORA14B Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA14B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SNORA14 35
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SNORA14 35
  • 79 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia SNORA14 35 35
  • 57 (a)
ManyToMany
chicken
(Gallus gallus)
Aves SNORA14 35
  • 62 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia SNORA14 35
  • 63 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii SNORA14 35 35
  • 50 (a)
ManyToMany
Species where no ortholog for SNORA14B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SNORA14B Gene

ENSEMBL:
Gene Tree for SNORA14B (if available)
TreeFam:
Gene Tree for SNORA14B (if available)

Paralogs for SNORA14B Gene

No data available for Paralogs for SNORA14B Gene

Variants for SNORA14B Gene

Sequence variations from dbSNP and Humsavar for SNORA14B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111732764 -- 235,127,370(+) TCAAG(A/G)TCTGA intron-variant, downstream-variant-500B
rs1130507 -- 235,128,639(-) CGACC(A/G)CAAAA upstream-variant-2KB, reference, missense
rs113559965 -- 235,127,511(+) CACTG(C/G)TCACA intron-variant, downstream-variant-500B
rs11543204 -- 235,128,645(-) CTACT(C/T)CGACC upstream-variant-2KB, reference, missense
rs115578971 -- 235,127,620(+) CTTTA(A/G)TAACT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for SNORA14B Gene

Variant ID Type Subtype PubMed ID
nsv508699 CNV deletion 20534489
esv3891237 CNV loss 25118596
esv3578486 CNV loss 25503493
esv275126 CNV loss 21479260

Relevant External Links for SNORA14B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNORA14B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA14B Gene

Disorders for SNORA14B Gene

Relevant External Links for SNORA14B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SNORA14B

No disorders were found for SNORA14B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA14B Gene

Publications for SNORA14B Gene

  1. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3 64
  2. Human box H/ACA pseudouridylation guide RNA machinery. (PMID: 15199136) Kiss A.M. … Kiss T. (Mol. Cell. Biol. 2004) 2 3 64
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3 64

Products for SNORA14B Gene

Sources for SNORA14B Gene

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