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Aliases for SNORA12 Gene

Subcategory (RNA class) for SNORA12 Gene


Quality Score for this RNA gene is


Aliases for SNORA12 Gene

  • Small Nucleolar RNA, H/ACA Box 12 2 3
  • U108 SnoRNA 3
  • U108 3

External Ids for SNORA12 Gene

Previous GeneCards Identifiers for SNORA12 Gene

  • GC10M101986
  • GC10M095625
  • GC10M101998
  • GC10M102002

Summaries for SNORA12 Gene

Entrez Gene Summary for SNORA12 Gene

  • Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA12, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]

GeneCards Summary for SNORA12 Gene

SNORA12 (Small Nucleolar RNA, H/ACA Box 12) is an RNA Gene, and is affiliated with the snoRNA class.

fRNAdb sequence ontologies for SNORA12 Gene - the ORGUL cluster for this gene includes several descriptions:

  • H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.

  • Small nucleolar RNA SNORA12: U108 belongs to the H/ACA family of snoRNAs. The sequence is predicted to guide the pseudouridylation of the U372 residue in the 28S rRNA subunit. However it has not been reported as a pseudouridylation site.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA12 Gene

Genomics for SNORA12 Gene

Regulatory Elements for SNORA12 Gene

Genomic Location for SNORA12 Gene

100,237,156 bp from pter
100,237,302 bp from pter
147 bases
Minus strand

Genomic View for SNORA12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SNORA12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SNORA12 Gene

ORGUL Member Location for SNORA12 Gene

ORGUL Member Location for SNORA12 gene

Proteins for SNORA12 Gene

Post-translational modifications for SNORA12 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNORA12 Gene

Domains for SNORA12 Gene

Gene Families for SNORA12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SNORA12: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA12 Gene

Function for SNORA12 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA12 Gene

Localization for SNORA12 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNORA12 Gene

Pathways for SNORA12 Gene

SuperPathways for SNORA12 Gene

No Data Available

Interacting Proteins for SNORA12 Gene

Gene Ontology (GO) - Biological Process for SNORA12 Gene


No data available for Pathways by source for SNORA12 Gene

Transcripts for SNORA12 Gene

mRNA/cDNA for SNORA12 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SNORA12 Gene

Small nucleolar RNA, H/ACA box 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SNORA12 Gene

No ASD Table

Relevant External Links for SNORA12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SNORA12 Gene

mRNA expression in normal human tissues for SNORA12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SNORA12 Gene Hs.662165

genes like me logo Genes that share expressions with SNORA12: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SNORA12 Gene

Orthologs for SNORA12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SNORA12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SNORA12 36
  • 87 (a)
(Canis familiaris)
Mammalia SNORA12 36
  • 89 (a)
(Monodelphis domestica)
Mammalia SNORA12 36
  • 67 (a)
(Mus musculus)
Mammalia Gm24336 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia SNORA12 36
  • 59 (a)
(Pan troglodytes)
Mammalia SNORA12 36
  • 99 (a)
(Gallus gallus)
Aves SNORA12 36
  • 53 (a)
Species with no ortholog for SNORA12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SNORA12 Gene

Gene Tree for SNORA12 (if available)
Gene Tree for SNORA12 (if available)

Paralogs for SNORA12 Gene

No data available for Paralogs for SNORA12 Gene

Variants for SNORA12 Gene

Structural Variations from Database of Genomic Variants (DGV) for SNORA12 Gene

Variant ID Type Subtype PubMed ID
nsv895922 CNV Loss 21882294
nsv516860 CNV Loss 19592680

Relevant External Links for SNORA12 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for SNORA12 Gene

Disorders for SNORA12 Gene

No disorders were found for SNORA12 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SNORA12 Gene

Publications for SNORA12 Gene

  1. A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu A.D. … Qu L.H. (Nucleic Acids Res. 2005) 2 3
  2. snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L. … Weber M.J. (Nucleic Acids Res. 2006) 2 3
  3. Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G. … Montanini B. (Genomics 2009) 3
  4. Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PMID: 21103663) Schaafhausen A. … MA1ller C.R. (Thromb. Haemost. 2011) 3

Products for SNORA12 Gene

Sources for SNORA12 Gene

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