Aliases for SNORA12 Gene
Subcategory (RNA class) for SNORA12 Gene
Quality Score for this RNA gene is
External Ids for SNORA12 Gene
- HGNC: 32600
- Entrez Gene: 677800
- Ensembl: ENSG00000212464
- OMIM: 611330
ORGUL Members for SNORA12 Gene
Previous GeneCards Identifiers for SNORA12 Gene
- GC10M101986
- GC10M095625
- GC10M101998
- GC10M102002
- GC10M100238
Summaries for SNORA12 Gene
-
Small nucleolar RNAs (snoRNAs) are small noncoding RNAs involved in RNA processing. Box H/ACA snoRNAs, such as SNORA12, direct the conversion of uridine to pseudouridine at specific residues of ribosomal RNAs or small nuclear RNAs (snRNAs) (Gu et al., 2005).[supplied by OMIM, Mar 2008]
GeneCards Summary for SNORA12 Gene
SNORA12 (Small Nucleolar RNA, H/ACA Box 12) is an RNA Gene, and is affiliated with the snoRNA class.
fRNAdb sequence ontologies for SNORA12 Gene - the ORGUL cluster for this gene includes several descriptions:
-
H_ACA_box_snoRNA: Members of the box H/ACA family contain an ACA triplet, exactly 3 nt upstream from the 3' end and an H-box in a hinge region that links two structurally similar functional domains of the molecule. Both boxes are important for snoRNA biosynthesis and function. A few box H/ACA snoRNAs are involved in rRNA processing; most others are known or predicted to participate in selection of uridine nucleosides in rRNA to be converted to pseudouridines. Site selection is mediated by direct base pairing of the snoRNA with rRNA through one or both targeting domains.
-
Small nucleolar RNA SNORA12: U108 belongs to the H/ACA family of snoRNAs. The sequence is predicted to guide the pseudouridylation of the U372 residue in the 28S rRNA subunit. However it has not been reported as a pseudouridylation site.
Additional gene information for SNORA12 Gene
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for SNORA12 Gene
Genomics for SNORA12 Gene
GeneHancer (GH) Regulatory Elements for SNORA12 Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH10I100246 | Promoter | 0.5 | EPDnew | 0.4 | -9.6 | -9603 | 0.1 | CWF19L1 PHBP9 BLOC1S2 ENSG00000236308 ERLIN1 GC10M100239 SNORA12 |
- Top Transcription factor binding sites by QIAGEN in the SNORA12 gene promoter:
Regulatory Element Products
Genomic Locations for SNORA12 Gene
- chr10:100,237,156-100,237,302
- (GRCh38/hg38)
- Size:
- 147 bases
- Orientation:
- Minus strand
- chr10:101,996,913-101,997,059
- (GRCh37/hg19)
Genomic View for SNORA12 Gene
- Cytogenetic band:
-
- 10q24.31 by Ensembl
- 10q24.31 by Entrez Gene
- 10q24.31 by HGNC


RefSeq DNA sequence for SNORA12 Gene
ORGUL Member Location for SNORA12 Gene

Proteins for SNORA12 Gene
Post-translational modifications for SNORA12 Gene
Antibody Products
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Protein Products
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- Search GeneTex for Proteins for SNORA12
No data available for DME Specific Peptides for SNORA12 Gene
Domains & Families for SNORA12 Gene
Gene Families for SNORA12 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNORA12 Gene
Function for SNORA12 Gene
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-
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-
Vectors and viruses for KO, Activation, Repression, and more
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SNORA12
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNORA12 Gene
Localization for SNORA12 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for SNORA12 Gene
Transcripts for SNORA12 Gene
mRNA/cDNA for SNORA12 Gene
- (2) Additional mRNA sequences :
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for SNORA12 Gene
CRISPR Products
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-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
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Clone Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for SNORA12
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for SNORA12 Gene
NURSA nuclear receptor signaling pathways regulating expression of SNORA12 Gene:
SNORA12SOURCE GeneReport for Unigene cluster for SNORA12 Gene:
Hs.662165Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNORA12 Gene
Orthologs for SNORA12 Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | SNORA12 34 |
|
OneToOne | |
dog (Canis familiaris) |
Mammalia | SNORA12 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | SNORA12 34 |
|
OneToOne | |
mouse (Mus musculus) |
Mammalia | Gm24336 34 |
|
OneToOne | |
oppossum (Monodelphis domestica) |
Mammalia | SNORA12 34 |
|
OneToMany | |
platypus (Ornithorhynchus anatinus) |
Mammalia | SNORA12 34 |
|
OneToMany | |
chicken (Gallus gallus) |
Aves | SNORA12 34 |
|
OneToMany |
- Species where no ortholog for SNORA12 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for SNORA12 Gene
No data available for Paralogs for SNORA12 Gene
Variants for SNORA12 Gene
SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000866778 | -- | 100,238,812(-) | G/A | upstream_transcript_variant | |
rs1001096657 | -- | 100,239,142(-) | C/G | upstream_transcript_variant | |
rs1001152180 | -- | 100,237,200(-) | T/C/G | non_coding_transcript_variant | |
rs1006815150 | -- | 100,237,422(-) | A/G | upstream_transcript_variant | |
rs1007728227 | -- | 100,238,396(-) | A/G | upstream_transcript_variant |
Additional Variant Information for SNORA12 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- SNORA12
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SNORA12 Gene
Disorders for SNORA12 Gene
Additional Disease Information for SNORA12
No disorders were found for SNORA12 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SNORA12 Gene
Publications for SNORA12 Gene
- snoRNA-LBME-db, a comprehensive database of human H/ACA and C/D box snoRNAs. (PMID: 16381836) Lestrade L … Weber MJ (Nucleic acids research 2006) 1 2 3 58
- A novel experimental approach for systematic identification of box H/ACA snoRNAs from eukaryotes. (PMID: 16361266) Gu AD … Qu LH (Nucleic acids research 2005) 1 2 3 58
- Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation. (PMID: 21103663) Schaafhausen A … Müller CR (Thrombosis and haemostasis 2011) 3 58
- Eukaryotic snoRNAs: a paradigm for gene expression flexibility. (PMID: 19446021) Dieci G … Montanini B (Genomics 2009) 3 58
- The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. (PMID: 18089548) Genome Information Integration Project And H-Invitational 2 … Gojobori T (Nucleic acids research 2008) 1
Products for SNORA12 Gene
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for SNORA12
- Search GeneTex for Proteins for SNORA12
Sources for SNORA12 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
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- (17) IUBMB
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- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
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- (84) Vector BioLabs
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- (98) CYP
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- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
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- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew