Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



SNN Gene

protein-coding   GIFtS: 50
GCID: GC16P011669

Stannin

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
stannin1 2
AG8_12 3

External Ids:    HGNC: 111491   Entrez Gene: 83032   Ensembl: ENSG000001846027   OMIM: 6030325   UniProtKB: O753243   

Export aliases for SNN gene to outside databases

Previous GC identifers: GC16P011545 GC16P011914 GC16P011728


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for SNN Gene:
SNN (stannin) is a protein-coding gene. Diseases associated with SNN include cavernous hemangioma, and hemangioma.

UniProtKB/Swiss-Prot: SNN_HUMAN, O75324
Function: Plays a role in the toxic effects of organotins

Gene Wiki entry for SNN Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNN gene promoter:
         N-Myc   SREBP-1a   p53   SREBP-1c   Nkx2-5   NF-kappaB   NF-kappaB1   SREBP-1b   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SNN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13   Ensembl cytogenetic band:  16p13.13   HGNC cytogenetic band: 16p13

SNN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNN gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P011669:  view genomic region     (about GC identifiers)

Start:
11,762,270 bp from pter      End:
11,773,015 bp from pter
Size:
10,746 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: SNN_HUMAN, O75324 (See protein sequence)
Recommended Name: Stannin  
Size: 88 amino acids; 9497 Da
Subunit: Monomer
1 PDB 3D structure from and Proteopedia for SNN:
1ZZA (3D)    
Secondary accessions: D3DUG4 Q6FGI0

Explore the universe of human proteins at neXtProt for SNN: NX_O75324

Explore proteomics data for SNN at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SNN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003489.1  
    ENSEMBL proteins: 
     ENSP00000329287  

    SNN Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SNN
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SNN
    GenScript Custom Purified and Recombinant Proteins Services for SNN
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNN

    SNN Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SNN
    Novus Biologicals SNN Antibody
    Abcam antibodies for SNN
    Cloud-Clone Corp. Antibodies for SNN
    Search ThermoFisher Antibodies for SNN
    Search LSBio for Antibodies for SNN

    SNN Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SNN
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SNN
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SNN
    Cloud-Clone Corp. CLIAs for SNN


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    4 InterPro protein domains:
     IPR015137 SNN_cytoplasm
     IPR027435 Stannin
     IPR015135 SNN_transmemb
     IPR015136 SNN_linker

    Graphical View of Domain Structure for InterPro Entry O75324

    ProtoNet protein and cluster: O75324

    UniProtKB/Swiss-Prot: SNN_HUMAN, O75324
    Similarity: Belongs to the stannin family


    SNN for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNN_HUMAN, O75324
    Function: Plays a role in the toxic effects of organotins

         Genatlas biochemistry entry for SNN:
    stannin,involved in the toxic effect of organotins

    Phenotypes:
         1 GenomeRNAi human phenotype for SNN:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNN
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SNN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNN

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SNN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNN (see all 74):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-199a-3p hsa-miR-298 hsa-miR-149 hsa-miR-489 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidSNN 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SNN
    Predesigned siRNA for gene silencing in human, mouse, rat SNN

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SNN

    Clone
    Products:
         
    OriGene clones in human, mouse for SNN (see all 6)
    OriGene ORF clones in mouse, rat for SNN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNN (NM_003498)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNN

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SNN
    Browse ESI BIO Cell Lines and PureStem Progenitors for SNN 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    SNN_HUMAN, O75324: Mitochondrion outer membrane; Single-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular3
    nucleus2
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005741mitochondrial outer membrane IEA--
    GO:0016021integral component of membrane IEA--

    SNN for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Array including SNN: 
              Drug Metabolism in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for SNN

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for SNN (O753243 ENSP000003292874) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAZP631043, ENSP000003095034I2D: score=1 STRING: ENSP00000309503
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006950response to stress TAS9657854
    GO:0009628response to abiotic stimulus TAS9657854

    SNN for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNN

    3 Novoseek inferred chemical compound relationships for SNN gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    trimethyltin 94.1 35 15798003 (5), 8786553 (4), 1635553 (3), 16246365 (3) (see all 8)
    dimethyltin 91.5 3 15521759 (1), 15923056 (1)
    lipid 0 4 16246365 (3), 16453279 (1)



    SNN for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for SNN gene: 
    NM_003498.5  

    Unigene Cluster for SNN:

    Stannin
    Hs.618526  [show with all ESTs]
    Unigene Representative Sequence: NM_003498
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000329565(uc002dbf.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SNN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNN (see all 74):
    hsa-miR-194* hsa-miR-3194-5p hsa-miR-188-5p hsa-miR-199a-3p hsa-miR-298 hsa-miR-149 hsa-miR-489 hsa-miR-3613-3p
    SwitchGear 3'UTR luciferase reporter plasmidSNN 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SNN
    Predesigned siRNA for gene silencing in human, mouse, rat SNN
    Clone
    Products:
         
    OriGene clones in human, mouse for SNN (see all 6)
    OriGene ORF clones in mouse, rat for SNN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNN (NM_003498)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNN
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SNN
    OriGene qSTAR qPCR primer pairs in human, mouse for SNN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNN
      QuantiTect SYBR Green Assays in human, mouse, rat SNN
      QuantiFast Probe-based Assays in human, mouse, rat SNN

    Additional mRNA sequence: 

    AF030196.1 AK025795.1 AL161976.1 BC005837.2 BC036100.1 BC036443.1 CR542127.1 CR542138.1 

    12 DOTS entries:

    DT.447430  DT.40126694  DT.95135635  DT.120656172  DT.120656151  DT.95167065  DT.100752122  DT.120656143 
    DT.120656203  DT.120656222  DT.101980962  DT.120656220 

    Selected AceView cDNA sequences (see all 197):

    BP349802 BE387731 W72938 F11990 AW292025 AI216843 BX444792 F04556 
    CB305719 F02682 F03757 NM_003498 AA907804 AI937275 BM985224 AA604431 
    AF030196 BC036100 AI216840 AA911492 F09637 CB155309 AW058083 BX094465 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    SNN expression in normal human tissues (normalized intensities)      SNN embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGAATGAAT
    SNN Expression
    About this image


    SNN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Heart (Cardiovascular System)
             Cushion Mesenchymal Cells Endocardium
     
     Amnion (Extraembryonic Tissues)
    SNN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.618526
        Pathway & Disease-focused RT2 Profiler PCR Array including SNN: 
              Drug Metabolism in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for SNN
    OriGene qSTAR qPCR primer pairs in human, mouse for SNN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNN
    QuantiTect SYBR Green Assays in human, mouse, rat SNN
    QuantiFast Probe-based Assays in human, mouse, rat SNN
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for SNN gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snn1 , 5 stannin1, 5 89.02(n)1
    97.73(a)1
      16 (6.32 cM)5
    206211  NM_009223.31  NP_033249.11 
     110662985 
    chicken
    (Gallus gallus)
    Aves SNN1 stannin 81.01(n)
    95.35(a)
      416429  XM_004945089.1  XP_004945146.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNN6
    stannin
    78(a)
    1 ↔ 1
    GL343691.1(286547-286813)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.84902 Xenopus laevis transcribed sequence with moderate similarity more 80(n)    BJ096958.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj47f062 Danio rerio cDNA clone MGC73221 IMAGE4144075, complete more 79.84(n)    BC060919.1 


    ENSEMBL Gene Tree for SNN (if available)
    TreeFam Gene Tree for SNN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for SNN (see all 286)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1508129481,2
    --11760390(+) CAGTCC/TGATCA 1 -- us2k10--------
    rs1394167291,2
    --11760419(+) ATGTAC/TTCAGC 1 -- us2k10--------
    rs615305281,2
    C,F--11760459(+) GACACA/GGCAGT 1 -- us2k13Minor allele frequency- G:0.19CSA WA 121
    rs1930625731,2
    --11760576(+) TAATCC/GCAGCA 1 -- us2k10--------
    rs1477319351,2
    --11760658(+) CTCTAC/TAAAAA 1 -- us2k10--------
    rs81912591,2
    C,F--11760695(+) catgcA/Gcctgt 1 -- us2k12Minor allele frequency- G:0.02NS CSA 154
    rs1855801401,2
    --11760814(+) TCTCTA/TAAAAA 1 -- us2k10--------
    rs1888423271,2
    --11761030(+) GGGAGA/GGCCCT 1 -- us2k10--------
    rs1443424031,2
    --11761058(+) TAAGCA/TGAGAT 1 -- us2k10--------
    rs1144588971,2
    C,F--11761110(+) ATAGGC/TAAAGG 1 -- us2k11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for SNN (11762270 - 11773015 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SNN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv524676CNV Loss19592680
    esv22331CNV Loss19812545
    nsv457409CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNN
    DNA2.0 Custom Variant and Variant Library Synthesis for SNN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 603032    OMIM disorders: --

    4 diseases for SNN:    About MalaCards
    cavernous hemangioma    hemangioma    endotheliitis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for SNN:
    Cavernous hemangioma

    SNN for disorders           About GeneDecksing

    3 Novoseek inferred disease relationships for SNN gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    intoxication 33.5 2 16246365 (1)
    necrosis 11.7 3 10233894 (1), 15798003 (1), 16572589 (1)
    tumors 0 3 10233894 (1), 15798003 (1), 16572589 (1)

    Genetic Association Database (GAD): SNN

    Export disorders for SNN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for SNN gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with SNN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosomal localization and characterization of the stannin (Snn) gene. (PubMed id 9657854)1, 2, 3, 9 Dejneka N.S....Billingsley M.L. (Mamm. Genome 1998)
    2. Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes. (PubMed id 10233894)1, 2, 9 Horrevoets A.J.G.... Pannekoek H. (Blood 1999)
    3. Common variants at ten loci influence QT interval duration in the QTGEN Study. (PubMed id 19305408)1, 4 Newton-Cheh C.... Stricker B.H. (Nat. Genet. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Localization and characterization of stannin: relationship to cellular sensitivity to organotin compounds. (PubMed id 9413842)1, 9 Dejneka N.S....Billingsley M.L. (Neurochem. Int. 1997)
    6. Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride. (PubMed id 16246365)2, 9 Buck-Koehntop B.A.... Veglia G. (J. Mol. Biol. 2005)
    7. Molecular neurotoxicology of trimethyltin: identification of stannin, a novel protein expressed in trimethyltin-sensitive cells. (PubMed id 1635553)1, 9 Toggas S.M....Billingsley M.L. (Mol. Pharmacol. 1992)
    8. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 8303 HGNC: 11149 AceView: SNN Ensembl:ENSG00000184602 euGenes: HUgn8303
    ECgene: SNN H-InvDB: SNN

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for SNN Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/snn/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for SNN gene:
    Search GeneIP for patents involving SNN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SNN  
     OriGene qPCR primer pairs and template standards for SNN   OriGene Protein Over-expression Lysate for SNN  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SNN  
     OriGene qSTAR qPCR primer pairs in human, mouse for SNN   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SNN   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SNN   OriGene Custom Protein Services for SNN  

     
     
     Block miRNA regulation of human, mouse, rat SNN using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SNN
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNN Predesigned siRNA for gene silencing in human, mouse, rat SNN
     QuantiFast Probe-based Assays in human, mouse, rat SNN QuantiTect SYBR Green Assays in human, mouse, rat SNN
     PCR Arrays including human, mouse, rat SNN Search Chromatin IP Primers for SNN
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNN  Search GeneGlobe Interaction Network for SNN
     Regulatory tfbs in SNN promoter
     GenScript Custom Purified and Recombinant Proteins Services for SNN GenScript cDNA clones with any tag delivered in your preferred vector for SNN
     GenScript Custom Assay Services for SNN GenScript Custom overexpressing Cell Line Services for SNN
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for SNN
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     SNN antibodies
     Antibodies for SNN
     See all of Abcam's Antibodies, Kits and Proteins for SNN
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for SNN
     Antibodies for SNN
     ELISAs for SNN
     CLIAs for SNN



     Browse ESI BIO Cell Lines and PureStem Progenitors for SNN
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNN
     SwitchGear 3'UTR luciferase reporter plasmids for SNN
     Browse SwitchGear Promoter luciferase reporter plasmids for SNN
     Search ThermoFisher Antibodies for SNN
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNN
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNN
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SNN
     Search LSBio for Antibodies for SNN
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SNN gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4