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Aliases for SNHG14 Gene

Subcategory (RNA class) for SNHG14 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SNHG14 Gene

  • Small Nucleolar RNA Host Gene 14 2 3 5
  • Small Nucleolar RNA Host Gene 14 (Non-Protein Coding) 2 3
  • UBE3A Antisense RNA 1 (Non-Protein Coding) 2 3
  • Large Noncoding Antisense Transcript 3
  • Non-Protein Coding RNA 214 2
  • UBE3A Antisense Transcript 3
  • IC-SNURF-SNRPN 3
  • U-UBE3A-ATS 3
  • NCRNA00214 3
  • UBE3A-AS1 3
  • UBE3A-AS 3
  • UBE3AATS 3
  • 115HG 3
  • LNCAT 3

External Ids for SNHG14 Gene

Previous HGNC Symbols for SNHG14 Gene

  • UBE3A-AS1

Previous GeneCards Identifiers for SNHG14 Gene

  • GC00U933595
  • GC15P025225
  • GC15P024985
  • GC15P025007
  • GC15P025018

Summaries for SNHG14 Gene

Entrez Gene Summary for SNHG14 Gene

  • This gene is located within the Prader-Willi critical region and produces a long, spliced paternally-imprinted RNA that initiates within a common upstream promoter region shared by the SNRPN (small nuclear ribonucleoprotein polypeptide N) and SNURF genes. This transcript serves as a host RNA for the small nucleolar RNA, C/D box 115 and 116 clusters. This RNA extends in antisense into the region of the ubiquitin protein ligase E3A gene (UBE3A), and is thought to regulate imprinted expression of UBE3A in the brain. This transcript undergoes extensive alternative splicing, and may initiate and terminate at multiple locations within this genomic region. The full-length structure of all splice forms is not determined. [provided by RefSeq, Mar 2017]

GeneCards Summary for SNHG14 Gene

SNHG14 (Small Nucleolar RNA Host Gene 14) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with SNHG14 include Angelman Syndrome.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SNHG14 Gene

Genomics for SNHG14 Gene

Regulatory Elements for SNHG14 Gene

Enhancers for SNHG14 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G024856 1 Ensembl ENCODE 7 -120.4 -120352 4.3 CTCF TFAP4 FOXA2 SAP130 TEAD4 CEBPG CHD7 GATA2 POLR2A FOS SNRPN SNHG14 ENSG00000280118 PIR42622
GH15G025134 0.4 ENCODE 11.5 +156.2 156186 0.2 CTCF POLR2A SNORD116-29 SNORD116-30 SNHG14 ENSG00000212428 SNORD115-2 SNORD115-1 SNORD116-27 SNORD116-26 SNORD116-25 ENSG00000270523
GH15G024846 0.6 ENCODE 7 -131.1 -131125 2.2 PAF1 CTCF POLR2A GABPB1 CHD7 RAD21 GABPA SNHG14 ENSG00000280118 SNRPN
GH15G024784 0.4 ENCODE 4.3 -193.8 -193814 0.5 MAFK SNHG14 PIR54184 PIR61722
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SNHG14 on UCSC Golden Path with GeneCards custom track

Genomic Location for SNHG14 Gene

Chromosome:
15
Start:
24,978,583 bp from pter
End:
25,419,462 bp from pter
Size:
440,880 bases
Orientation:
Plus strand

Genomic View for SNHG14 Gene

Genes around SNHG14 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SNHG14 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SNHG14 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for SNHG14 Gene

Proteins for SNHG14 Gene

Post-translational modifications for SNHG14 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SNHG14 Gene

Domains & Families for SNHG14 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SNHG14 Gene

Function for SNHG14 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SNHG14 Gene

Localization for SNHG14 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SNHG14 Gene

Pathways & Interactions for SNHG14 Gene

SuperPathways for SNHG14 Gene

No Data Available

Interacting Proteins for SNHG14 Gene

Gene Ontology (GO) - Biological Process for SNHG14 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SNHG14 Gene

Drugs & Compounds for SNHG14 Gene

No Compound Related Data Available

Transcripts for SNHG14 Gene

mRNA/cDNA for SNHG14 Gene

(26) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SNHG14 Gene

No ASD Table

Relevant External Links for SNHG14 Gene

GeneLoc Exon Structure for
SNHG14
ECgene alternative splicing isoforms for
SNHG14

Expression for SNHG14 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SNHG14 Gene

NURSA nuclear receptor signaling pathways regulating expression of SNHG14 Gene:

SNHG14
genes like me logo Genes that share expression patterns with SNHG14: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SNHG14 Gene

Orthologs for SNHG14 Gene

Evolution for SNHG14 Gene

ENSEMBL:
Gene Tree for SNHG14 (if available)
TreeFam:
Gene Tree for SNHG14 (if available)

No data available for Orthologs for SNHG14 Gene

Paralogs for SNHG14 Gene

No data available for Paralogs for SNHG14 Gene

Variants for SNHG14 Gene

Relevant External Links for SNHG14 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SNHG14

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SNHG14 Gene

Disorders for SNHG14 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SNHG14 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
angelman syndrome
  • happy puppet syndrome
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with SNHG14: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for SNHG14 Gene

Publications for SNHG14 Gene

  1. Long non-coding RNA SNHG14 promotes microglia activation by regulating miR-145-5p/PLA2G4A in cerebral infarction. (PMID: 28215748) Qi X. … Huo W. (Neuroscience 2017) 2 3 64
  2. A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure. (PMID: 23771028) Powell W.T. … Lasalle J.M. (Hum. Mol. Genet. 2013) 2 3 64
  3. Angelman syndrome-derived neurons display late onset of paternal UBE3A silencing. (PMID: 27484051) Stanurova J. … Steenpass L. (Sci Rep 2016) 3 64
  4. Differential regulation of non-protein coding RNAs from Prader-Willi Syndrome locus. (PMID: 25246219) Galiveti C.R. … Rozhdestvensky T.S. (Sci Rep 2014) 3 64
  5. Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model. (PMID: 24385930) Meng L. … Beaudet A.L. (PLoS Genet. 2013) 3 64

Products for SNHG14 Gene

Sources for SNHG14 Gene

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