Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNED1 Gene

protein-coding   GIFtS: 43
GCID: GC02P241938

Sushi, Nidogen And EGF-Like Domains 1

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sushi, Nidogen And EGF-Like Domains 11 2     SST32
Insulin-Responsive Sequence DNA-Binding Protein 12 3     Snep2
IRE-BP12 3     Insulin Responsive Sequence DNA Binding Protein-12
6720455I24Rik Homolog2     Sushi, Nidogen And EGF-Like Domain-Containing Protein 12

External Ids:    HGNC: 246961   Entrez Gene: 259922   Ensembl: ENSG000001628047   UniProtKB: Q8TER03   

Export aliases for SNED1 gene to outside databases

Previous GC identifers: GC02P241658 GC02P241586 GC02P233694


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SNED1 Gene: 
SNED1 (sushi, nidogen and EGF-like domains 1) is a protein-coding gene. Diseases associated with SNED1 include islet cell tumor. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is DLK2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005416.13  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNED1 gene promoter:
         AML1a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SNED1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNED1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

SNED1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNED1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P241938:  view genomic region     (about GC identifiers)

Start:
241,938,255 bp from pter      End:
242,034,983 bp from pter
Size:
96,729 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SNED1_HUMAN, Q8TER0 (See protein sequence)
Recommended Name: Sushi, nidogen and EGF-like domain-containing protein 1 precursor  
Size: 1413 amino acids; 152204 Da
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAH27939.1; Type=Miscellaneous discrepancy; Note=Intron retention. The N-terminal
region arises from intron retention; Sequence=AAQ04558.1; Type=Erroneous initiation;
Secondary accessions: B5MDC3 B7WNK6 B7WPM0 Q336F4 Q336F5 Q8N369 Q8TEP7
Alternative splicing: 4 isoforms:  Q8TER0-1   Q8TER0-3   Q8TER0-4   Q8TER0-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SNED1: NX_Q8TER0

Explore proteomics data for SNED1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TER0

  • SNED1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SNED1 Protein Expression
    REFSEQ proteins: NP_001073906.1  
    ENSEMBL proteins: 
     ENSP00000384871   ENSP00000386007   ENSP00000308893   ENSP00000384789   ENSP00000401865  
     ENSP00000394324   ENSP00000342992  

    Human Recombinant Protein Products for SNED1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for SNED1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SNED1
    GenScript Custom Purified and Recombinant Proteins Services for SNED1
    Novus Biologicals SNED1 Protein
    Novus Biologicals SNED1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNED1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    SNED1 for ontologies           About GeneDecksing



    SNED1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SNED1
    GenScript Custom Superior Antibodies Services for SNED1
    Novus Biologicals SNED1 Antibodies
    Abcam antibodies for SNED1
    Cloud-Clone Corp. Antibodies for SNED1 
    Search ThermoFisher Antibodies for SNED1
    LSBio Antibodies in human, mouse, rat for SNED1 

    Assay Products for SNED1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for SNED1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SNED1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SNED1 
    Cloud-Clone Corp. CLIAs for SNED1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FN3: Fibronectin type III domain containing

    5/10 InterPro protein domains (see all 10):
     IPR003886 Nidogen_extracell_dom
     IPR001881 EGF-like_Ca-bd
     IPR000742 EG-like_dom
     IPR003961 Fibronectin_type3
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q8TER0

    ProtoNet protein and cluster: Q8TER0

    3 Blocks protein domains:
    IPB000152 Aspartic acid and asparagine hydroxylation site
    IPB001881 EGF-like calcium-binding
    IPB003886 Nidogen


    UniProtKB/Swiss-Prot: SNED1_HUMAN, Q8TER0
    Similarity: Contains 15 EGF-like domains
    Similarity: Contains 3 fibronectin type-III domains
    Similarity: Contains 2 follistatin-like domains
    Similarity: Contains 1 NIDO domain
    Similarity: Contains 1 Sushi (CCP/SCR) domain


    SNED1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----
         
    SNED1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SNED1:
     Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SNED1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SNED1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNED1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNED1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNED1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SNED1:
    hsa-miR-3673 hsa-miR-206 hsa-miR-3184 hsa-miR-1 hsa-miR-423-5p hsa-miR-298 hsa-miR-1264 hsa-miR-613
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SNED1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNED1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SNED1
    Sirion Biotech Customized adenovirus for overexpression of SNED1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for SNED1 (see all 7)
    OriGene ORF clones in mouse, rat for SNED1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNED1 (NM_001080437)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNED1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNED1
    Sirion Biotech Customized lentivirus for stable overexpression of SNED1 
                         Customized lentivirus expression plasmids for stable overexpression of SNED1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SNED1
    Search LifeMap BioReagents cell lines for SNED1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNED1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SNED1

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007160cell-matrix adhesion IEA--

    SNED1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SNED1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNED1

    1 Novoseek inferred chemical compound relationship for SNED1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    octreotide 69.1 3 11931345 (1), 11980628 (1)

    Search CenterWatch for drugs/clinical trials and news about SNED1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNED1 gene: 
    NM_001080437.1  

    Unigene Cluster for SNED1:

    Sushi, nidogen and EGF-like domains 1
    Hs.471834  [show with all ESTs]
    Unigene Representative Sequence: BX640653
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000401884(uc002wak.3) ENST00000405547(uc002waj.1) ENST00000310397(uc002wah.1)
    ENST00000493358 ENST00000401644 ENST00000431690 ENST00000420591 ENST00000469006
    ENST00000483962 ENST00000466618(uc002wai.1) ENST00000491761(uc002wal.3)
    ENST00000342631
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNED1
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SNED1:
    hsa-miR-3673 hsa-miR-206 hsa-miR-3184 hsa-miR-1 hsa-miR-423-5p hsa-miR-298 hsa-miR-1264 hsa-miR-613
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SNED1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNED1
    Clone
    Products:
         
    OriGene clones in human, mouse for SNED1 (see all 7)
    OriGene ORF clones in mouse, rat for SNED1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNED1 (NM_001080437)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNED1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNED1
    Sirion Biotech Customized lentivirus for stable overexpression of SNED1 
                         Customized lentivirus expression plasmids for stable overexpression of SNED1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SNED1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNED1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNED1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNED1

    Additional mRNA sequence: 

    AF439717.1 AF439718.1 AK074062.1 AK074075.1 AL050143.1 BC027939.1 BX640653.1 BX640872.1 

    9 DOTS entries:

    DT.412312  DT.100026333  DT.100746862  DT.100690320  DT.415499  DT.97842383  DT.100008381  DT.121013140 
    DT.99998449 

    24/124 AceView cDNA sequences (see all 124):

    BQ674435 AA666033 T33009 BU682448 BQ001117 AA385063 BF509657 AI559669 
    BU615846 BQ230598 CA390846 AA477132 BF928844 AA659919 CK725167 BF448827 
    AI697432 CA441902 AK074062 Z41119 BM545959 BU631161 BX640872 BF061416 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SNED1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20
    SP1:                                                                                                              -     -                     
    SP2:                                                                                                                                          
    SP3:                                                                                                                    -                     
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for SNED1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNED1 expression in normal human tissues (normalized intensities)      SNED1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SNED1 Expression
    About this image


    SNED1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/16 selected tissues (see all 16) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebellum
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Sclerotome cells
             synovial membrane   
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Mesoderm (Gastrulation Derivatives)
             mesenchyme/trunk mesenchyme   
     
     Somite (Muscoskeletal System)
             Sclerotome cells

    See SNED1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNED1

    SOURCE GeneReport for Unigene cluster: Hs.471834
        SABiosciences Custom PCR Arrays for SNED1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for SNED1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNED1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNED1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNED1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNED1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SNED1 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sned11 , 5 sushi, nidogen and EGF-like domains 11, 5 84.01(n)1
    84.54(a)1
      1 (47.21 cM)5
    2087771  NM_172463.41  NP_766051.41 
     932358415 
    chicken
    (Gallus gallus)
    Aves SNED11 sushi, nidogen and EGF-like domains 1 74.03(n)
    71.28(a)
      424846  XM_003641748.1  XP_003641796.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNED16
    Uncharacterized protein
    67(a)
    1 ↔ 1
    3(30018147-30086640)
    zebrafish
    (Danio rerio)
    Actinopterygii sned11 sushi, nidogen and EGF-like domains 1 57.32(n)
    54.17(a)
      100001751  XM_001341654.3  XP_001341690.3 
    worm
    (Caenorhabditis elegans)
    Secernentea crb-16
    Protein CRB-1
    12(a)
    1 → many
    X(17402804-17413849)


    ENSEMBL Gene Tree for SNED1 (if available)
    TreeFam Gene Tree for SNED1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNED1 gene
    DLK22  SLIT22  SLIT12  DLL32  JAG22  DLL42  DLK12  JAG12  
    DNER2  SLIT32  SVEP12  DLL12  
    18/25 SIMAP similar genes for SNED1 using alignment to 5 protein entries:     SNED1_HUMAN (see all proteins) (see all similar genes):
    F9    NCAN    NOTCH3    FAT3    CRB1    F7
    F9 p22    MMRN1    factor IX F9    CNTNAP2    PAMR1    FBN3
    UMOD    FAT2    SLIT2    NELL1    PROS1    TNXB

    SNED1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SNED1
    PGOHUM00000234668


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2074 SNPs in SNED1 are shown (see all 2074)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs43449301,2
    C,F,H--241936268(-) AGAACG/ACTTTT 1 -- us2k121Minor allele frequency- A:0.12NS EA NA WA 2760
    rs1827001681,2
    --241936309(+) GCTCTA/GTTCCC 1 -- us2k10--------
    rs1151933301,2
    F--241936390(+) GACCAG/TGGAGG 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1419166781,2
    --241936431(+) ATGTTA/CTTGAG 1 -- us2k10--------
    rs134162801,2
    C,F--241936439(+) GAGGCC/TCCACG 1 -- us2k12Minor allele frequency- T:0.18WA 120
    rs1862646221,2
    --241936464(+) GCCTCC/TGTGCA 1 -- us2k10--------
    rs1506091881,2
    --241936499(+) TGGACA/GTGTGT 1 -- us2k10--------
    rs133902961,2
    C,F,A,H--241936681(+) GGGACG/CGTGAC 1 -- us2k114Minor allele frequency- C:0.28NA NS EA WA CSA 794
    rs1387396751,2
    --241936810(+) GCCAGG/TGCAGG 1 -- us2k10--------
    rs1495271371,2
    --241936985(+) GGCTCC/TCACTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNED1 (241938255 - 242034983 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/22 variations for SNED1 (see all 22):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2721968CNV Deletion23290073
    dgv772e199CNV Deletion23128226
    esv2721969CNV Deletion23290073
    esv2200022CNV Deletion18987734
    esv2721967CNV Deletion23290073
    esv2077609CNV Deletion18987734
    esv2721971CNV Deletion23290073
    esv2721966CNV Deletion23290073
    esv2721970CNV Deletion23290073
    esv2675882CNV Deletion23128226

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SNED1
    DNA2.0 Custom Variant and Variant Library Synthesis for SNED1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SNED1:    About MalaCards
    islet cell tumor    


    SNED1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for SNED1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 4.65 1 9284735 (1)


    Export disorders for SNED1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNED1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with SNED1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    2. Genome-wide association study of circulating estradiol , testosterone, and sex hormone-binding globulin in postmenopausal women. (PubMed id 22675492)1 Prescott J....De Vivo I. (2012)
    3. Keratinocyte-associated protein 2 is a bona fide subun it of the mammalian oligosaccharyltransferase. (PubMed id 22266900)1 Roboti P. and High S. (2012)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    5. Insulin-response element-binding protein 1: a novel Akt substrate involved in transcriptional action of insulin. (PubMed id 15194686)2 Villafuerte B.C.... Zhao W. (2004)
    6. Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein. (PubMed id 15162516)1 Leimeister C....Gessler M. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. Drug design at peptide receptors: somatostatin receptor ligands. (PubMed id 11931345)9 Hannon J.P....Hoyer D. (2002)
    9. Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors. (PubMed id 9284735)9 Hofland L.J....Lamberts S.W. (1997)
    10. Anxiolytic and antidepressant actions of somatostatin : the role of sst2 and sst3 receptors. (PubMed id 19609508)9 Engin E. and Treit D. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25992 HGNC: 24696 AceView: FLJ00133.1 Ensembl:ENSG00000162804 euGenes: HUgn25992
    ECgene: SNED1 H-InvDB: SNED1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNED1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNED1 gene:
    Search GeneIP for patents involving SNED1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SNED1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for SNED1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for SNED1  
     OriGene qSTAR qPCR primer pairs in human, mouse for SNED1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for SNED1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SNED1   OriGene Custom Protein Services for SNED1  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SNED1
     QIAGEN SeqTarget long-range PCR primers for resequencing SNED1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNED1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNED1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNED1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNED1
     GenScript Custom Purified and Recombinant Proteins Services for SNED1 GenScript cDNA clones with any tag delivered in your preferred vector for SNED1
     GenScript Custom Assay Services for SNED1 GenScript Custom Superior Antibodies Services for SNED1
     GenScript Custom overexpressing Cell Line Services for SNED1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SNED1 promoter
     Search Chromatin IP Primers for SNED1
     RT2 qPCR Primer Assay in human, mouse, rat SNED1
     Search GNC Networks for SNED1
     SABiosciences Custom PCR Arrays for SNED1
     Search Tocris compounds for SNED1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SNED1 antibodies
     SNED1 proteins
     SNED1 lysates
     Antibodies for SNED1
     See all of Abcam's Antibodies, Kits and Proteins for SNED1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for SNED1
     Antibodies for SNED1
     ELISAs for SNED1
     CLIAs for SNED1
     Search LifeMap BioReagents cell lines for SNED1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNED1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for SNED1
     Browse SwitchGear Promoter luciferase reporter plasmids for SNED1
     Search ThermoFisher Antibodies for SNED1
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNED1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for SNED1
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SNED1
    Customized:
     lentivirus for stable overexpression of SNED1
     lentivirus expression plasmids for stable overexpression of SNED1
     adenovirus for overexpression of SNED1
     LSBio Antibodies in human, mouse, rat for SNED1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SNED1 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4