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SNED1 Gene

protein-coding   GIFtS: 45
GCID: GC02P241938

Sushi, Nidogen And EGF-Like Domains 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sushi, Nidogen And EGF-Like Domains 11 2     SST32
Insulin-Responsive Sequence DNA-Binding Protein 12 3     Snep2
IRE-BP12 3     Insulin Responsive Sequence DNA Binding Protein-12
6720455I24Rik Homolog2     Sushi, Nidogen And EGF-Like Domain-Containing Protein 12

External Ids:    HGNC: 246961   Entrez Gene: 259922   Ensembl: ENSG000001628047   UniProtKB: Q8TER03   

Export aliases for SNED1 gene to outside databases

Previous GC identifers: GC02P241658 GC02P241586 GC02P233694


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SNED1 Gene:
SNED1 (sushi, nidogen and EGF-like domains 1) is a protein-coding gene. Diseases associated with SNED1 include islet cell tumor, and meningitis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is DLK2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNED1 gene promoter:
         AML1a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SNED1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNED1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q37.3   Ensembl cytogenetic band:  2q37.3   HGNC cytogenetic band: 2q37.3

SNED1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNED1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P241938:  view genomic region     (about GC identifiers)

Start:
241,938,255 bp from pter      End:
242,034,983 bp from pter
Size:
96,729 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SNED1_HUMAN, Q8TER0 (See protein sequence)
Recommended Name: Sushi, nidogen and EGF-like domain-containing protein 1 precursor  
Size: 1413 amino acids; 152204 Da
Sequence caution: Sequence=AAH27939.1; Type=Miscellaneous discrepancy; Note=Intron retention. The N-terminal
region arises from intron retention; Sequence=AAQ04558.1; Type=Erroneous initiation;
Secondary accessions: B5MDC3 B7WNK6 B7WPM0 Q336F4 Q336F5 Q8N369 Q8TEP7
Alternative splicing: 4 isoforms:  Q8TER0-1   Q8TER0-3   Q8TER0-4   Q8TER0-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SNED1: NX_Q8TER0

Explore proteomics data for SNED1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn145, Asn408, Asn977, Ser1247
  • Modification sites at PhosphoSitePlus

  • See SNED1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001073906.1  
    ENSEMBL proteins: 
     ENSP00000384871   ENSP00000386007   ENSP00000308893   ENSP00000384789   ENSP00000401865  
     ENSP00000394324   ENSP00000342992  

    SNED1 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for SNED1
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    Novus Biologicals SNED1 Protein
    Novus Biologicals SNED1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNED1

    SNED1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for SNED1

    SNED1 Assay Products:

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    Cloud-Clone Corp. ELISAs for SNED1
    Cloud-Clone Corp. CLIAs for SNED1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FN3: Fibronectin type III domain containing

    Selected InterPro protein domains (see all 10):
     IPR000742 EG-like_dom
     IPR003961 Fibronectin_type3
     IPR000436 Sushi_SCR_CCP
     IPR000152 EGF-type_Asp/Asn_hydroxyl_site
     IPR018097 EGF_Ca-bd_CS

    Graphical View of Domain Structure for InterPro Entry Q8TER0

    ProtoNet protein and cluster: Q8TER0

    3 Blocks protein domains:
    IPB000152 Aspartic acid and asparagine hydroxylation site
    IPB001881 EGF-like calcium-binding
    IPB003886 Nidogen


    UniProtKB/Swiss-Prot: SNED1_HUMAN, Q8TER0
    Similarity: Contains 15 EGF-like domains
    Similarity: Contains 3 fibronectin type-III domains
    Similarity: Contains 2 follistatin-like domains
    Similarity: Contains 1 NIDO domain
    Similarity: Contains 1 Sushi (CCP/SCR) domain


    SNED1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----
         
    SNED1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SNED1:
     Decreased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNED1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SNED1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNED1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNED1

    miRNA
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    miRTarBase miRNAs that target SNED1:
    hsa-mir-335-5p (MIRT016924)

    Block miRNA regulation of human, mouse, rat SNED1 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate SNED1:
    hsa-miR-3673 hsa-miR-206 hsa-miR-3184 hsa-miR-1 hsa-miR-423-5p hsa-miR-298 hsa-miR-1264 hsa-miR-613
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SNED1
    Predesigned siRNA for gene silencing in human, mouse, rat SNED1

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for SNED1

    Clone
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    OriGene ORF clones in mouse, rat for SNED1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNED1 (NM_001080437)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNED1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNED1

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for SNED1
    Browse ESI BIO Cell Lines and PureStem Progenitors for SNED1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNED1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNED1_HUMAN, Q8TER0: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    plasma membrane3
    nucleus2
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    SNED1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNED1
    Interactions:

        Search GeneGlobe Interaction Network for SNED1

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007160cell-matrix adhesion IEA--

    SNED1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNED1

    1 Novoseek inferred chemical compound relationship for SNED1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    octreotide 69.1 3 11931345 (1), 11980628 (1)



    SNED1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SNED1 gene: 
    NM_001080437.1  

    Unigene Cluster for SNED1:

    Sushi, nidogen and EGF-like domains 1
    Hs.471834  [show with all ESTs]
    Unigene Representative Sequence: BX640653
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000401884(uc002wak.3) ENST00000405547(uc002waj.1) ENST00000310397(uc002wah.1)
    ENST00000493358 ENST00000401644 ENST00000431690 ENST00000420591 ENST00000469006
    ENST00000483962 ENST00000466618(uc002wai.1) ENST00000491761(uc002wal.3)
    ENST00000342631
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SNED1 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate SNED1:
    hsa-miR-3673 hsa-miR-206 hsa-miR-3184 hsa-miR-1 hsa-miR-423-5p hsa-miR-298 hsa-miR-1264 hsa-miR-613
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SNED1
    Predesigned siRNA for gene silencing in human, mouse, rat SNED1
    Clone
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    OriGene clones in human, mouse for SNED1 (see all 6)
    OriGene ORF clones in mouse, rat for SNED1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNED1 (NM_001080437)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNED1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SNED1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SNED1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNED1
      QuantiTect SYBR Green Assays in human, mouse, rat SNED1
      QuantiFast Probe-based Assays in human, mouse, rat SNED1

    Additional mRNA sequence: 

    AF439717.1 AF439718.1 AK074062.1 AK074075.1 AL050143.1 BC027939.1 BX640653.1 BX640872.1 

    9 DOTS entries:

    DT.412312  DT.100026333  DT.100746862  DT.100690320  DT.415499  DT.97842383  DT.100008381  DT.121013140 
    DT.99998449 

    Selected AceView cDNA sequences (see all 124):

    AA477132 AA666033 BQ230598 AK074062 CA390846 BF928844 AA385063 BQ001117 
    Z41119 BF448827 BU682448 CA427414 BU615846 BF061416 BU631161 BM545959 
    BU186124 AI559669 BX640872 AI697432 CA441902 Z45408 BQ675103 BQ674435 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SNED1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20
    SP1:                                                                                                              -     -                     
    SP2:                                                                                                                                          
    SP3:                                                                                                                    -                     
    SP4:                                                                                                                                          
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for SNED1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNED1 expression in normal human tissues (normalized intensities)      SNED1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SNED1 Expression
    About this image


    SNED1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 12) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebellum
     
     Thymus (Hematopoietic System)
             Double Positive Thymocytes Thymus
     
     Bone (Muscoskeletal System)
             Sclerotome cells
     
     Kidney (Urinary System)
             Metanephros
     
     Cartilage (Muscoskeletal System)
             Sclerotome cells
    SNED1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNED1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.471834
        Custom PCR Arrays for SNED1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNED1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SNED1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sned11 , 5 sushi, nidogen and EGF-like domains 11, 5 84.04(n)1
    84.54(a)1
      1 (47.21 cM)5
    2087771  NM_172463.41  NP_766051.41 
     932358415 
    chicken
    (Gallus gallus)
    Aves SNED11 sushi, nidogen and EGF-like domains 1 74.19(n)
    71.71(a)
      424846  XM_003641748.2  XP_003641796.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNED16
    sushi, nidogen and EGF-like domains 1
    68(a)
    1 ↔ 1
    3(30018147-30086640)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sned11 sushi, nidogen and EGF-like domains 1 58.2(n)
    53.13(a)
      100498350  XM_002933337.2  XP_002933383.2 
    zebrafish
    (Danio rerio)
    Actinopterygii sned11 sushi, nidogen and EGF-like domains 1 57.34(n)
    53.43(a)
      100001751  XM_001341654.4  XP_001341690.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta uif6
    C9016
    C901
    9(a)
    23(a)
    many ↔ many
    many ↔ many
    2L(6972828-7010312)
    X(10858152-10861167)
    worm
    (Caenorhabditis elegans)
    Secernentea lin-126
    Protein LIN-12 (lin-12) mRNA, complete cds
    15(a)
    many ↔ many
    III(9060242-9071760) WBGene00003001


    ENSEMBL Gene Tree for SNED1 (if available)
    TreeFam Gene Tree for SNED1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNED1 gene
    DLK22  NOTCH42  NOTCH12  DLL32  NOTCH32  DLL42  JAG22  CRB22  
    DLK12  NOTCH22  JAG12  DNER2  CRB12  DLL12  
    Selected SIMAP similar genes for SNED1 using alignment to 5 protein entries:     SNED1_HUMAN (see all proteins) (see all similar genes):
    F9    NCAN    NOTCH3    FAT3    CRB1    F7
    F9 p22    MMRN1    factor IX F9    CNTNAP2    PAMR1    FBN3
    UMOD    FAT2    PLAU    SLIT2    NELL1    PROS1

    SNED1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SNED1
    PGOHUM00000234668


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNED1 (see all 2074)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs43449301,2
    C,F,H--241936268(-) AGAACG/ACTTTT 1 -- us2k121Minor allele frequency- A:0.12NS EA NA WA 2760
    rs1827001681,2
    --241936309(+) GCTCTA/GTTCCC 1 -- us2k10--------
    rs1151933301,2
    F--241936390(+) GACCAG/TGGAGG 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1419166781,2
    --241936431(+) ATGTTA/CTTGAG 1 -- us2k10--------
    rs134162801,2
    C,F--241936439(+) GAGGCC/TCCACG 1 -- us2k12Minor allele frequency- T:0.18WA 120
    rs1862646221,2
    --241936464(+) GCCTCC/TGTGCA 1 -- us2k10--------
    rs1506091881,2
    --241936499(+) TGGACA/GTGTGT 1 -- us2k10--------
    rs133902961,2
    C,F,A,H--241936681(+) GGGACG/CGTGAC 1 -- us2k114Minor allele frequency- C:0.28NA NS EA WA CSA 794
    rs1387396751,2
    --241936810(+) GCCAGG/TGCAGG 1 -- us2k10--------
    rs1495271371,2
    --241936985(+) GGCTCC/TCACTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNED1 (241938255 - 242034983 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SNED1 (see all 22):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2721968CNV Deletion23290073
    dgv772e199CNV Deletion23128226
    esv2721969CNV Deletion23290073
    esv2200022CNV Deletion18987734
    esv2721967CNV Deletion23290073
    esv2077609CNV Deletion18987734
    esv2721971CNV Deletion23290073
    esv2721966CNV Deletion23290073
    esv2721970CNV Deletion23290073
    esv2675882CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNED1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for SNED1:    About MalaCards
    islet cell tumor    meningitis    choroiditis


    SNED1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for SNED1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 4.65 1 9284735 (1)


    Export disorders for SNED1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNED1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with SNED1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    2. Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women. (PubMed id 22675492)1 Prescott J....De Vivo I. (PLoS ONE 2012)
    3. Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase. (PubMed id 22266900)1 Roboti P. and High S. (J. Cell. Sci. 2012)
    4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    5. Insulin-response element-binding protein 1: a novel Akt substrate involved in transcriptional action of insulin. (PubMed id 15194686)2 Villafuerte B.C.... Zhao W. (J. Biol. Chem. 2004)
    6. Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein. (PubMed id 15162516)1 Leimeister C....Gessler M. (Dev. Dyn. 2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Drug design at peptide receptors: somatostatin receptor ligands. (PubMed id 11931345)9 Hannon J.P....Hoyer D. (J. Mol. Neurosci. 2002)
    9. Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors. (PubMed id 9284735)9 Hofland L.J....Lamberts S.W. (J. Clin. Endocrinol. Metab. 1997)
    10. Anxiolytic and antidepressant actions of somatostatin: the role of sst2 and sst3 receptors. (PubMed id 19609508)9 Engin E. and Treit D. (Psychopharmacology (Berl.) 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25992 HGNC: 24696 AceView: FLJ00133.1 Ensembl:ENSG00000162804 euGenes: HUgn25992
    ECgene: SNED1 H-InvDB: SNED1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SNED1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SNED1 gene:
    Search GeneIP for patents involving SNED1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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