Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SND1 Gene

protein-coding   GIFtS: 54
GCID: GC07P127292

staphylococcal nuclease and tudor domain containing 1

 Explore 5 diseases affiliated with
SND1 via our new
 Human Malady Compendium 
Biological research products
for SND1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Staphylococcal Nuclease And Tudor Domain Containing 11 2     EBNA-2 Co-Activator (100kD)2
TDRD111 2 3     P100 EBNA2 Co-Activator2
P1005     SND1-BRAF Fusion2
Tudor Domain-Containing Protein 112 3     Staphylococcal Nuclease Domain Containing 12
100 KDa Coactivator2 3     Staphylococcal Nuclease Domain-Containing Protein 12
EBNA2 Coactivator P1002 3     P1005
P100 Co-Activator2 3     

External Ids:    HGNC: 306461   Entrez Gene: 270442   Ensembl: ENSG000001971577   OMIM: 6021815   UniProtKB: Q7KZF43   

Export aliases for SND1 gene to outside databases

Previous GC identifers: GC07P126846 GC07P126886 GC07P127079 GC07P121653


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
Function: Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1
regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2
(EBNA2)

Gene Wiki entry for SND1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SND1 gene promoter:
         TBP   HFH-3   AML1a   CUTL1   Evi-1   FOXI1   TFIID   c-Myb   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 14): SND1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SND1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SND1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.3   Ensembl cytogenetic band:  7q32.1   HGNC cytogenetic band: 7q31.3

SND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SND1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P127292:  view genomic region     (about GC identifiers)

Start:
127,292,202 bp from pter      End:
127,732,661 bp from pter
Size:
440,460 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 126,675,657-127,115,790     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4 (See protein sequence)
Recommended Name: Staphylococcal nuclease domain-containing protein 1  
Size: 910 amino acids; 101997 Da
Subunit: Binds to acidic transactivation domain of EBNA2. Interacts with EAV NSP1. Interacts with GTF2E1 and GTF2E2.
Forms a ternary complex with STAT6 and POLR2A. Interacts with STAT5 (By similarity)
Subcellular location: Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the
nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Sequence caution: Sequence=AAA80488.1; Type=Frameshift; Positions=5; Note=The frameshift leads to wrong initiation;
6/7 PDB 3D structures from and Proteopedia for SND1 (see all 7):
2E6N (3D)        2HQE (3D)        2HQX (3D)        2O4X (3D)        3BDL (3D)        3OMC (3D)    
Secondary accessions: Q13122 Q96AG0

Explore the universe of human proteins at neXtProt for SND1: NX_Q7KZF4

Post-translational modifications:

  • Phosphorylated by PIM1 in vitro1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q7KZF4

  • SND1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055205.2  
    ENSEMBL proteins: 
     ENSP00000346762   ENSP00000419327  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: SND1
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for SND1 
    GenScript Custom Purified and Recombinant Proteins Services for SND1
    Novus Biologicals SND1 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SND1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--
    GO:0016442RNA-induced silencing complex IEA--
    GO:0042470melanosome IEA--


    SND1 for ontologies           About GeneDecksing



    SND1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for SND1 
    GenScript Custom Superior Antibodies Services for SND1
    Novus Biologicals SND1 Antibodies
    Search for Antibodies for SND1 at Abcam  
    Uscn Antibodies for SND1
    ThermoFisher Antibodies for SND1

    Assay Products for SND1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for SND1
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for SND1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SND1 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR006021 Staphylococcal_nuclease
     IPR016685 Silence_cplx_Nase-comp_TudorSN
     IPR016071 Staphylococal_nuclease_OB-fold
     IPR002071 Thermonucl_AS
     IPR002999 Tudor

    Graphical View of Domain Structure for InterPro Entry Q7KZF4

    ProtoNet protein and cluster: Q7KZF4

    1 Blocks protein family: IPB008191 Maternal tudor protein

    UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
    Similarity: Contains 4 TNase-like domains
    Similarity: Contains 1 Tudor domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
    Function: Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1
    regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2
    (EBNA2)

    miRNA
    Products:
        
    OriGene 3'-UTR Clone: SND1
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SND1
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SND1 (see all 12):
    hsa-miR-320a hsa-miR-361-5p hsa-miR-3166 hsa-miR-1324 hsa-miR-320d hsa-miR-1224-5p hsa-miR-320b hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidSND1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SND1 (see all 7)
    OriGene shRNA RFP: SND1
    OriGene siRNA: SND1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SND1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SND1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SND1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SND1 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SND1 (NM_014390)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SND1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SND1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for SND1
    Search LifeMap BioReagents cell lines for SND1

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SND1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0003712transcription cofactor activity TAS7651391
    GO:0004518nuclease activity IEA--
    GO:0016788hydrolase activity, acting on ester bonds ----


    SND1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SND1:
     Synthetic lethal with c-Myc af 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1C-MYB transcription factor network
    C-MYB transcription factor network1.00


    1 BioSystems Pathway for SND1 
        C-MYB transcription factor network


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SND1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/596 Interacting proteins for SND1 (Q7KZF42, 3 ENSP000003467624) via UniProtKB, MINT, STRING, and/or I2D (see all 596)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBA5Q9GZZ92, 3, ENSP000003485654MINT-7945693 I2D: score=3 STRING: ENSP00000348565
    DHX9Q082112, 3, ENSP000003565204MINT-7945693 I2D: score=1 STRING: ENSP00000356520
    SNW1Q135732, 3, ENSP000002615314MINT-7945693 I2D: score=1 STRING: ENSP00000261531
    PRKAG1P546192, 3MINT-7945693 I2D: score=1 
    G3BP1Q132832, 3, ENSP000003485784MINT-7968779 MINT-7968768 MINT-7968789 I2D: score=1 STRING: ENSP00000348578
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0019048virus-host interaction IEA--
    GO:0031047gene silencing by RNA IEA--
    GO:0044419interspecies interaction between organisms ----


    SND1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SND1
    Search CenterWatch for drugs/clinical trials and news about SND1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SND1 gene: 
    NM_014390.2  

    Unigene Cluster for SND1:

    Staphylococcal nuclease and tudor domain containing 1
    Hs.122523  [show with all ESTs]
    Unigene Representative Sequence: JX013981
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354725(uc003vmi.3 uc010lle.3) ENST00000463020 ENST00000461056
    ENST00000468621 ENST00000483503 ENST00000492772 ENST00000468166 ENST00000465900
    ENST00000486037 ENST00000484767 ENST00000492840 ENST00000470723 ENST00000467238
    ENST00000470463 ENST00000489417 ENST00000485871

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: SND1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SND1
    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SND1 (see all 12):
    hsa-miR-320a hsa-miR-361-5p hsa-miR-3166 hsa-miR-1324 hsa-miR-320d hsa-miR-1224-5p hsa-miR-320b hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidSND1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SND1 (see all 7)
    OriGene shRNA RFP: SND1
    OriGene siRNA: SND1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SND1
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SND1 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SND1 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: SND1 (NM_014390)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SND1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SND1 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SND1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SND1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SND1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SND1

    Additional cDNA sequence: 

    AB209510.1 AK096583.1 AK304181.1 AK309014.1 AK312313.1 AY273894.1 BC017180.2 BC020423.1 
    BT009785.1 JX013981.1 U22055.1 

    24/46 DOTS entries (see all 46):

    DT.450785  DT.91922113  DT.100845929  DT.100721250  DT.97855700  DT.95276353  DT.95240781  DT.95276368 
    DT.101974544  DT.95276373  DT.121105903  DT.92465216  DT.97855698  DT.121106003  DT.418871  DT.91754263 
    DT.95276347  DT.100845928  DT.100845933  DT.121105809  DT.121105815  DT.121105846  DT.121105927  DT.85105100 

    9 AceView cDNA sequences:

    BG468657 H52008 H52124 AW604661 BG824165 T19943 BE697320 AW604654 
    AW732848 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SND1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^
    SP1:                                                                    -                                                                             -         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -     -     -     -     -     -     -     -     -     -     -     -                                                         
    SP5:                                                                                                                                                            

    ExUns: 23a · 23b ^ 24 ^ 25a · 25b
    SP1:        -                     
    SP2:        -                     
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for SND1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SND1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGGAGGTGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SND1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SND1

    SOURCE GeneReport for Unigene cluster: Hs.122523

    UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
    Tissue specificity: Ubiquitously expressed

        SABiosciences Custom PCR Arrays for SND1
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SND1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SND1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SND1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SND1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SND1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SND1 gene from 8/32 species (see all 32)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snd11 , 5 staphylococcal nuclease and tudor domain containing more1, 5 90.77(n)1
    97.36(a)1
      6 (11.99 cM)5
    564631  NM_019776.21  NP_062750.21 
     284751395 
    lizard
    (Anolis carolinensis)
    Reptilia SND16
    --
    95(a)
    1 ↔ 1
    GL344065.1(65934-69461)
    African clawed frog
    (Xenopus laevis)
    Amphibia 2e999-prov2 staphylococcal nuclease domain containing 1 77.77(n)    BC043884.1 
    zebrafish
    (Danio rerio)
    Actinopterygii snd12 staphylococcal nuclease domain containing 1 77.64(n)   324404  AY272050.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tudor-SN1 CG7008-PA 54.49(n)
    52.76(a)
      38045  NM_138177.2  NP_612021.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tsn-11 Protein TSN-1 53.91(n)
    49.03(a)
      173811  NM_062438.5  NP_494839.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons Tudor21 TUDOR-SN protein 2 48.03(n)
    39.36(a)
      836300  NM_125572.2  NP_200986.1 
    rice
    (Oryza sativa)
    Liliopsida AK065061.12   -- 72.39(n)    AK065061.1 


    ENSEMBL Gene Tree for SND1 (if available)
    TreeFam Gene Tree for SND1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/5930 NCBI SNPs in SND1 are shown (see all 5930    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1460580551,2
    --127290271(+) TGACAC/TCTTGA 1 -- us2k10--------
    rs1400040741,2
    --127290391(+) TTTGGA/GGCAAA 1 -- us2k10--------
    rs1807280491,2
    --127290420(+) AAGATA/GTAAGA 1 -- us2k10--------
    rs624813611,2
    --127290464(+) AGTTAT/CGATCA 1 -- us2k12Minor allele frequency- C:0.04NA 122
    rs1164684221,2
    F,--127290553(+) GCAGAG/AGTCAA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1856354991,2
    --127290562(+) AAGTTC/TACTGA 1 -- us2k10--------
    rs711795941,2
    C--127290770(-) AAAAAAA/-ACCTC 1 -- us2k11Minor allele frequency- -:0.00NA 2
    rs1904356321,2
    --127290821(+) GGATCC/TAAGAA 1 -- us2k10--------
    rs1169330261,2
    F,--127290876(+) ATAAAC/TTTACA 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1817455191,2
    --127290906(+) GGCCAC/TGCACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SND1 (127292202 - 127542202 bp, first 250kb of SND1)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for SND1
         2 CNVs: 100111 100112
         3 Indels: 12962 47224 62722

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SND1
    DNA2.0 Custom Variant and Variant Library Synthesis for SND1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SND1 for disorders           About GeneDecksing

    OMIM gene information: 602181    OMIM disorders: --

    5 diseases for SND1:    About MalaCards
    autism spectrum disorder    colon cancer    prostate cancer    prostatitis
    malaria

    Human Genome Epidemiology (HuGE) Navigator: SND1 (6 documents)

    Export disorders for SND1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SND1 gene, integrated from 9 sources (see all 75):
    (articles sorted by number of sources associating them with SND1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. (PubMed id 7651391)1, 2, 3 Tong X.... Kieff E. (1995)
    2. Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. (PubMed id 12234934)1, 2, 9 Yang J.... Silvennoinen O. (2002)
    3. The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development. (PubMed id 9003410)1, 3, 9 Callebaut I. and Mornon J.P. (1997)
    4. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    6. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Equine arteritis virus non-structural protein 1, an essential factor for viral subgenomic mRNA synthesis, interacts with the cellular transcription co-factor p100. (PubMed id 12917451)1, 2 Tijms M.A. and Snijder E.J. (2003)
    9. Tudor and nuclease-like domains containing protein p1 00 function as coactivators for signal transducer and activator of transcriptio n 5. (PubMed id 12819296)1, 3 Paukku K....Silvennoinen O. (2003)
    10. Pim-1 kinase and p100 cooperate to enhance c-Myb activity. (PubMed id 9809063)1, 2 Leverson J.D.... Ness S.A. (1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27044 HGNC: 30646 AceView: SND1 Ensembl:ENSG00000197157 euGenes: HUgn27044
    ECgene: SND1 H-InvDB: SND1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SND1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SND1 gene:
    Search GeneIP for patents involving SND1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for SND1  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SND1   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SND1  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for SND1   OriGene 3'-UTR Clone for SND1  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SND1   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SND1  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for SND1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for SND1   OriGene Custom Protein Services for SND1  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SND1
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SND1
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SND1
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SND1
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SND1
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SND1
     GenScript Custom Purified and Recombinant Proteins Services for SND1 GenScript cDNA clones with any tag delivered in your preferred vector for SND1
     GenScript Custom Assay Services for SND1 GenScript Custom Superior Antibodies Services for SND1
     GenScript Custom overexpressing Cell Line Services for SND1 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in SND1 promoter
     Search Chromatin IP Primers for SND1
     RT2 qPCR Primer Assay in human, mouse, rat SND1
     GNC Network for SND1
     SABiosciences Custom PCR Arrays for SND1
     Search Tocris compounds for SND1
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     SND1 antibodies
     SND1 proteins
     Search for Antibodies for SND1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for SND1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     SND1 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for SND1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SND1
     SwitchGear 3'UTR luciferase reporter plasmids for SND1
     SwitchGear Promoter luciferase reporter plasmids for SND1
     ThermoFisher Antibodies for SND1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SND1
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      SND1 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4