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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SND1 Gene

protein-coding   GIFtS: 57
GCID: GC07P127292

Staphylococcal Nuclease And Tudor Domain Containing 1

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Staphylococcal Nuclease And Tudor Domain Containing 11 2     EBNA-2 Co-Activator (100kD)2
P100 EBNA2 Co-Activator1 2     p1002
Tudor Domain-Containing Protein 112 3     SND1-BRAF Fusion2
100 KDa Coactivator2 3     Staphylococcal Nuclease Domain Containing 12
TDRD112 3     Staphylococcal Nuclease Domain-Containing Protein 12
EBNA2 Coactivator P1002 3     P1005
P100 Co-Activator2 3     

External Ids:    HGNC: 306461   Entrez Gene: 270442   Ensembl: ENSG000001971577   OMIM: 6021815   UniProtKB: Q7KZF43   

Export aliases for SND1 gene to outside databases

Previous GC identifers: GC07P126846 GC07P126886 GC07P127079 GC07P121653


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SND1 Gene: 
SND1 (staphylococcal nuclease and tudor domain containing 1) is a protein-coding gene. Diseases associated with SND1 include autism spectrum disorder, and kaposi's sarcoma. GO annotations related to this gene include nuclease activity and nucleic acid binding.

UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
Function: Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1
regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen
2 (EBNA2)

Gene Wiki entry for SND1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SND1 gene promoter:
         TBP   HFH-3   AML1a   CUTL1   Evi-1   FOXI1   TFIID   c-Myb   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 14): SND1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SND1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SND1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.3   Ensembl cytogenetic band:  7q32.1   HGNC cytogenetic band: 7q31.3

SND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SND1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P127292:  view genomic region     (about GC identifiers)

Start:
127,292,202 bp from pter      End:
127,732,661 bp from pter
Size:
440,460 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 126,675,657-127,115,790     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4 (See protein sequence)
Recommended Name: Staphylococcal nuclease domain-containing protein 1  
Size: 910 amino acids; 101997 Da
Subunit: Binds to acidic transactivation domain of EBNA2. Interacts with EAV NSP1. Interacts with GTF2E1 and
GTF2E2. Forms a ternary complex with STAT6 and POLR2A. Interacts with STAT5 (By similarity)
Subcellular location: Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the
nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Sequence caution: Sequence=AAA80488.1; Type=Frameshift; Positions=5; Note=The frameshift leads to wrong
initiation;
6/7 PDB 3D structures from and Proteopedia for SND1 (see all 7):
2E6N (3D)        2HQE (3D)        2HQX (3D)        2O4X (3D)        3BDL (3D)        3OMC (3D)    
Secondary accessions: Q13122 Q96AG0

Explore the universe of human proteins at neXtProt for SND1: NX_Q7KZF4

Explore proteomics data for SND1 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated by PIM1 in vitro
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7KZF4

  • SND1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SND1 Protein Expression
    REFSEQ proteins: NP_055205.2  
    ENSEMBL proteins: 
     ENSP00000346762   ENSP00000419327  

    Human Recombinant Protein Products for SND1: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SND1 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IEA--
    GO:0016442RISC complex IEA--
    GO:0042470melanosome IEA--

    SND1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TDRD: Tudor domain containing

    5 InterPro protein domains:
     IPR006021 Staphylococcal_nuclease
     IPR016685 Silence_cplx_Nase-comp_TudorSN
     IPR016071 Staphylococal_nuclease_OB-fold
     IPR002071 Thermonucl_AS
     IPR002999 Tudor

    Graphical View of Domain Structure for InterPro Entry Q7KZF4

    ProtoNet protein and cluster: Q7KZF4

    1 Blocks protein domain: IPB008191 Maternal tudor protein

    UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
    Similarity: Contains 4 TNase-like domains
    Similarity: Contains 1 Tudor domain


    SND1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SND1_HUMAN, Q7KZF4
    Function: Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1
    regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen
    2 (EBNA2)

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0003712transcription cofactor activity TAS7651391
    GO:0004518nuclease activity IEA--
    GO:0005515protein binding IPI--
    GO:0016788hydrolase activity, acting on ester bonds ----
         
    SND1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SND1:
     Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SND1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SND1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SND1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SND1 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidSND1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SND1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SND1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Viral carcinogenesis
    Viral carcinogenesis
    2Epstein-Barr virus infection
    Epstein-Barr virus infection
    3C-MYB transcription factor network
    C-MYB transcription factor network

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for SND1
        C-MYB transcription factor network


    2         Kegg Pathways  (Kegg details for SND1):
        Epstein-Barr virus infection
    Viral carcinogenesis


    SND1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SND1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/624 Interacting proteins for SND1 (Q7KZF42, 3 ENSP000003467624) via UniProtKB, MINT, STRING, and/or I2D (see all 624)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBA5Q9GZZ92, 3, ENSP000003485654MINT-7945693 I2D: score=3 STRING: ENSP00000348565
    DHX9Q082112, 3, ENSP000003565204MINT-7945693 I2D: score=1 STRING: ENSP00000356520
    SNW1Q135732, 3, ENSP000002615314MINT-7945693 I2D: score=1 STRING: ENSP00000261531
    PRKAG1P546192, 3MINT-7945693 I2D: score=1 
    G3BP1Q132832, 3, ENSP000003485784MINT-7968779 MINT-7968768 MINT-7968789 I2D: score=1 STRING: ENSP00000348578
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0019048modulation by virus of host morphology or physiology IEA--
    GO:0031047gene silencing by RNA IEA--

    SND1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SND1

    Search CenterWatch for drugs/clinical trials and news about SND1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SND1 gene: 
    NM_014390.2  

    Unigene Cluster for SND1:

    Staphylococcal nuclease and tudor domain containing 1
    Hs.122523  [show with all ESTs]
    Unigene Representative Sequence: NM_014390
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000354725(uc003vmi.3 uc010lle.3) ENST00000463020 ENST00000461056
    ENST00000468621 ENST00000483503 ENST00000492772 ENST00000468166 ENST00000465900
    ENST00000486037 ENST00000484767 ENST00000492840 ENST00000470723 ENST00000467238
    ENST00000470463 ENST00000489417 ENST00000485871
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SND1 (see all 12):
    hsa-miR-320a hsa-miR-361-5p hsa-miR-3166 hsa-miR-1324 hsa-miR-320d hsa-miR-1224-5p hsa-miR-320b hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidSND1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SND1
    Clone
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    OriGene ORF clones in mouse, rat for SND1
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    GenScript: all cDNA clones in your preferred vector: SND1 (NM_014390)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SND1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SND1
    Sirion Biotech Customized lentivirus for stable overexpression of SND1 
                         Customized lentivirus expression plasmids for stable overexpression of SND1 
    Primer
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    OriGene qPCR primer pairs and template standards for SND1
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SND1

    Additional mRNA sequence: 

    AB209510.1 AK096583.1 AK304181.1 AK309014.1 AK312313.1 AY273894.1 BC017180.2 BC020423.1 
    BT009785.1 U22055.1 

    24/46 DOTS entries (see all 46):

    DT.450785  DT.91922113  DT.100845929  DT.100721250  DT.97855700  DT.95276353  DT.95240781  DT.95276368 
    DT.101974544  DT.95276373  DT.121105903  DT.92465216  DT.97855698  DT.121106003  DT.418871  DT.91754263 
    DT.95276347  DT.100845928  DT.100845933  DT.121105809  DT.121105815  DT.121105846  DT.121105927  DT.85105100 

    9 AceView cDNA sequences:

    BG468657 H52008 AW604661 H52124 BG824165 BE697320 T19943 AW604654 
    AW732848 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SND1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^
    SP1:                                                                    -                                                                             -         
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -     -     -     -     -     -     -     -     -     -     -     -                                                         
    SP5:                                                                                                                                                            

    ExUns: 23a · 23b ^ 24 ^ 25a · 25b
    SP1:        -                     
    SP2:        -                     
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for SND1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SND1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGAGGTGC
    SND1 Expression
    About this image


    See SND1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SND1

    SOURCE GeneReport for Unigene cluster: Hs.122523

    UniProtKB/Swiss-Prot: SND1_HUMAN, Q7KZF4
    Tissue specificity: Ubiquitously expressed

        SABiosciences Custom PCR Arrays for SND1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SND1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SND1 gene from 8/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snd11 , 5 staphylococcal nuclease and tudor domain containing more1, 5 90.77(n)1
    97.36(a)1
      6 (11.99 cM)5
    564631  NM_019776.21  NP_062750.21 
     284751395 
    lizard
    (Anolis carolinensis)
    Reptilia SND16
    Uncharacterized protein
    96(a)
    1 ↔ 1
    GL344065.1(65934-69473)
    African clawed frog
    (Xenopus laevis)
    Amphibia 2e999-prov2 staphylococcal nuclease domain containing 1 77.77(n)    BC043884.1 
    zebrafish
    (Danio rerio)
    Actinopterygii snd12 staphylococcal nuclease domain containing 1 77.64(n)   324404  AY272050.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Tudor-SN1 CG7008-PA 54.49(n)
    52.76(a)
      38045  NM_138177.2  NP_612021.1 
    worm
    (Caenorhabditis elegans)
    Secernentea tsn-11 Protein TSN-1 53.91(n)
    49.03(a)
      173811  NM_062438.5  NP_494839.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons Tudor21 TUDOR-SN protein 2 48.03(n)
    39.36(a)
      836300  NM_125572.2  NP_200986.1 
    rice
    (Oryza sativa)
    Liliopsida AK065061.12   -- 72.39(n)    AK065061.1 


    ENSEMBL Gene Tree for SND1 (if available)
    TreeFam Gene Tree for SND1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6745 SNPs in SND1 are shown (see all 6745)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs719824651,2
    C--121976363(+) CCCTC-/GTGT  
      GTGTGT
    GTGTG
    1 -- int10--------
    rs1460580551,2
    --127290271(+) TGACAC/TCTTGA 1 -- us2k10--------
    rs1400040741,2
    --127290391(+) TTTGGA/GGCAAA 1 -- us2k10--------
    rs1807280491,2
    --127290420(+) AAGATA/GTAAGA 1 -- us2k10--------
    rs624813611,2
    C,F--127290464(+) AGTTAT/CGATCA 1 -- us2k12Minor allele frequency- C:0.04NA 122
    rs1164684221,2
    F--127290553(+) GCAGAG/AGTCAA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1856354991,2
    --127290562(+) AAGTTC/TACTGA 1 -- us2k10--------
    rs348357921,2
    C--127290770(+) GAGGT-/TT/TTT
            
    TTTTT
    2 -- us2k1 cds10--------
    rs1904356321,2
    --127290821(+) GGATCC/TAAGAA 1 -- us2k10--------
    rs1169330261,2
    F--127290876(+) ATAAAC/TTTACA 1 -- us2k11Minor allele frequency- T:0.03NA 120

    HapMap Linkage Disequilibrium report for SND1 (127292202 - 127542202 bp, first 250kb of SND1)

    Structural Variations
         Database of Genomic Variants (DGV) 10/19 variations for SND1 (see all 19):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2656712CNV Deletion23128226
    esv2735127CNV Deletion23290073
    esv2735126CNV Deletion23290073
    esv2401641CNV Deletion18987734
    esv2558418CNV Deletion19546169
    esv2663660CNV Deletion23128226
    esv997448CNV Deletion20482838
    esv267464CNV Insertion20981092
    esv2612143CNV Insertion19546169
    nsv5942CNV Insertion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602181    OMIM disorders: --

    7 diseases for SND1:    About MalaCards
    autism spectrum disorder    kaposi's sarcoma    colon cancer    sarcoma
    hepatocellular carcinoma    prostate cancer    prostatitis


    SND1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SND1
    Human Genome Epidemiology (HuGE) Navigator: SND1 (6 documents)

    Export disorders for SND1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SND1 gene, integrated from 9 sources (see all 88):
    (articles sorted by number of sources associating them with SND1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. (PubMed id 7651391)1, 2, 3 Tong X.... Kieff E. (1995)
    2. Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. (PubMed id 12234934)1, 2, 9 Yang J.... Silvennoinen O. (2002)
    3. The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development. (PubMed id 9003410)1, 3, 9 Callebaut I. and Mornon J.P. (1997)
    4. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    5. Linkage and candidate gene studies of autism spectrum disorders in European populations. (PubMed id 20442744)1, 4 Holt R....Monaco A.P. (2010)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    8. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)1, 2 Chi A....Hunt D.F. (2006)
    9. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    10. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27044 HGNC: 30646 AceView: SND1 Ensembl:ENSG00000197157 euGenes: HUgn27044
    ECgene: SND1 Kegg: 27044 H-InvDB: SND1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SND1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SND1 gene:
    Search GeneIP for patents involving SND1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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