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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNAPC4 Gene

protein-coding   GIFtS: 58
GCID: GC09M139270

Small Nuclear RNA Activating Complex, Polypeptide 4, 19...

(Previous names: small nuclear RNA activating complex, polypeptide 4, 19...)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Small Nuclear RNA Activating Complex, Polypeptide 4, 190kDa1 2     SNAPc Subunit 42 3
Proximal Sequence Element-Binding Transcription Factor Subunit Alpha2 3     SnRNA-Activating Protein Complex 190 KDa Subunit2 3
SNAP1902 3     Small Nuclear RNA Activating Complex, Polypeptide 4, 190kD1
PSE-Binding Factor Subunit Alpha2 3     PTFalpha2
PTF Subunit Alpha2 3     SnRNA-Activating Protein Complex Subunit 42
SNAPc 190 KDa Subunit2 3     

External Ids:    HGNC: 111371   Entrez Gene: 66212   Ensembl: ENSG000001656847   OMIM: 6027775   UniProtKB: Q5SXM23   

Export aliases for SNAPC4 gene to outside databases

Previous GC identifers: GC09M130337 GC09M130959 GC09M132711 GC09M134627 GC09M136545 GC09M138389 GC09M108729


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SNAPC4 Gene: 
SNAPC4 (small nuclear RNA activating complex, polypeptide 4, 190kDa) is a protein-coding gene. Diseases associated with SNAPC4 include crohn's disease, and hepatitis b, and among its related super-pathways are RNA Polymerase III Transcription Initiation From Type 3 Promoter and RNA Polymerase II Transcription. GO annotations related to this gene include chromatin binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is MYBL2.

UniProtKB/Swiss-Prot: SNPC4_HUMAN, Q5SXM2
Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear
RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2
types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

Gene Wiki entry for SNAPC4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_024000.16  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNAPC4 gene promoter:
         Pbx1a   p53   Pax-6   Olf-1   Lmo2   NRF-2   c-Myb   SEF-1 (1)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SNAPC4 promoter sequence
   Search SABiosciences Chromatin IP Primers for SNAPC4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNAPC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3   Ensembl cytogenetic band:  9q34.3   HGNC cytogenetic band: 9q34.3

SNAPC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNAPC4 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M139270:  view genomic region     (about GC identifiers)

Start:
139,270,029 bp from pter      End:
139,293,249 bp from pter
Size:
23,221 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SNPC4_HUMAN, Q5SXM2 (See protein sequence)
Recommended Name: snRNA-activating protein complex subunit 4  
Size: 1469 amino acids; 159433 Da
Subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC4
interacts with SNAPC1, SNAPC2, SNAPC5, BRF2 and TBP
Subcellular location: Nucleus (Potential)
Secondary accessions: Q9Y6P7

Explore the universe of human proteins at neXtProt for SNAPC4: NX_Q5SXM2

Explore proteomics data for SNAPC4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5SXM2

  • SNAPC4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SNAPC4 Protein Expression
    REFSEQ proteins: NP_003077.2  
    ENSEMBL proteins: 
     ENSP00000298532  
    Reactome Protein details: Q5SXM2
    Human Recombinant Protein Products for SNAPC4: 
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    Novus Biologicals SNAPC4 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SNAPC4 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC11056176
    GO:0005654nucleoplasm TAS--
    GO:0019185snRNA-activating protein complex IDA11056176

    SNAPC4 for ontologies           About GeneDecksing



    SNAPC4 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR017877 Myb-like_dom
     IPR001005 SANT/Myb
     IPR009057 Homeodomain-like
     IPR017930 Myb_dom

    Graphical View of Domain Structure for InterPro Entry Q5SXM2

    ProtoNet protein and cluster: Q5SXM2

    1 Blocks protein domain: IPB001005 Myb DNA-binding domain

    UniProtKB/Swiss-Prot: SNPC4_HUMAN, Q5SXM2
    Similarity: Contains 3 HTH myb-type DNA-binding domains
    Similarity: Contains 2 Myb-like domains


    SNAPC4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNPC4_HUMAN, Q5SXM2
    Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear
    RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2
    types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA11056176
    GO:0003682chromatin binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9418884
         
    SNAPC4 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Snapc4):
     mortality/aging  skeleton 

    SNAPC4 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SNAPC4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SNAPC4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNAPC4 
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    miRNA
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SNAPC4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation0.80
    RNA Polymerase III Transcription Initiation From Type 3 Promoter0.80
    RNA Polymerase III Transcription0.80
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    RNA Polymerase III Abortive And Retractive Initiation0.80
    2Transcription
    Transcription0.69
    3Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/7        Reactome Pathways for SNAPC4 (see all 7)
        RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation From Type 3 Promoter
    Transcription
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
    RNA Polymerase III Transcription



    SNAPC4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SNAPC4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/579 Interacting proteins for SNAPC4 (Q5SXM22, 3 ENSP000002985324) via UniProtKB, MINT, STRING, and/or I2D (see all 579)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8262000 I2D: score=2 
    EWSR1Q018442, 3MINT-7947479 I2D: score=1 
    SNAPC2Q134873, ENSP000002215734I2D: score=4 STRING: ENSP00000221573
    ATG16L1Q676U53, ENSP000003758724I2D: score=3 STRING: ENSP00000375872
    SNAPC1Q165333, ENSP000002162944I2D: score=3 STRING: ENSP00000216294
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006366transcription from RNA polymerase II promoter TAS9418884
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0009301snRNA transcription TAS9418884
    GO:0010467gene expression TAS--
    GO:0042795snRNA transcription from RNA polymerase II promoter IDA9418884

    SNAPC4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNAPC4 (SNPC4)

    Search CenterWatch for drugs/clinical trials and news about SNAPC4 / SNPC4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SNAPC4 gene: 
    NM_003086.2  

    Unigene Cluster for SNAPC4:

    Small nuclear RNA activating complex, polypeptide 4, 190kDa
    Hs.113265  [show with all ESTs]
    Unigene Representative Sequence: AF032387
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000298532(uc004chh.3)
    miRNA
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNAPC4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNAPC4

    Additional mRNA sequence: 

    AF032387.1 AK023513.1 BC013606.1 U56432.1 

    9 DOTS entries:

    DT.201607  DT.97799329  DT.100642522  DT.95337359  DT.99985299  DT.100010022  DT.121162936  DT.92026460 
    DT.95215602 

    24/71 AceView cDNA sequences (see all 71):

    BQ059414 CD616259 AK023513 AI889801 CD616249 BQ949543 CR618502 CD616257 
    CD616247 BX093431 CD557265 NM_003086 BF817279 AF032387 BX409698 BU160778 
    BX432984 AI631957 BU169977 CD616258 AI369312 BE263519 BU727137 BU688747 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SNAPC4 (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^
    SP1:                                                                                                                                                            
    SP2:                                -                                                                                                                           
    SP3:                                -                                                                                                                           
    SP4:                                -                                                                                                                           
    SP5:                                                                                                                                                  -         

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for SNAPC4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNAPC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGTTCCCC
    SNAPC4 Expression
    About this image


    See SNAPC4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNAPC4

    SOURCE GeneReport for Unigene cluster: Hs.113265
        SABiosciences Custom PCR Arrays for SNAPC4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNAPC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SNAPC4 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snapc41 , 5 small nuclear RNA activating complex, polypeptide 41, 5 73.2(n)1
    65.43(a)1
      2 (18.87 cM)5
    2276441  NM_172339.41  NP_758842.11 
     263627655 
    chicken
    (Gallus gallus)
    Aves SNAPC41 small nuclear RNA activating complex, polypeptide 4, more 56.99(n)
    52.93(a)
      417133  XM_415416.3  XP_415416.2 
    lizard
    (Anolis carolinensis)
    Reptilia SNAPC46
    Uncharacterized protein
    66(a)
    1 ↔ 1
    AAWZ02040763(773-6409)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5657351 uncharacterized LOC565735 51.93(n)
    43.23(a)
      565735  XM_003198661.1  XP_003198709.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pbp956
    PSEA-binding protein 95kD
    16(a)
    1 ↔ 1
    3R(3839546-3842332)
    worm
    (Caenorhabditis elegans)
    Secernentea gei-113 protooncogene C-MYB like 29(a)   I(8970409-8973982)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes BAS1(YKR099W)4 Myb-related transcription factor involved in regulating more   --   11(635851-638286) 853974  NP_013025.1 


    ENSEMBL Gene Tree for SNAPC4 (if available)
    TreeFam Gene Tree for SNAPC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SNAPC4 gene
    MYBL22  MYB2  MYBL12  

    SNAPC4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SNAPC4
    PGOHUM00000236791


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/925 SNPs in SNAPC4 are shown (see all 925)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs30880811,2
    C,F,A--139270149(+) TGGTCA/GGTCAG 1 -- ut31 ese314Minor allele frequency- G:0.40MN NA WA CSA EA 695
    rs1928003651,2
    --139270156(+) TCAGCA/GGCCAG 1 -- ut310--------
    rs1506108511,2
    --139270329(+) AAACAA/GGAACC 1 -- int10--------
    rs766731391,2
    F--139270340(+) AAGACC/TACCCC 1 -- int11Minor allele frequency- T:0.01NA 120
    rs567637631,2
    C,F--139270349(+) CCAGCG/ACCGGC 1 -- int12Minor allele frequency- A:0.06WA 120
    rs1139588851,2
    C,F--139270358(+) GCCACG/ACCCAG 1 -- int12Minor allele frequency- A:0.04CSA WA 120
    rs562497191,2
    C,F--139270372(+) GCTTGG/CTAAAC 1 -- int12Minor allele frequency- C:0.07WA 120
    rs1844044991,2
    --139270436(+) GAGCCA/TGCCTG 1 -- int10--------
    rs1892800831,2
    --139270500(+) ATGCAC/TGGGAA 1 -- int10--------
    rs1400382081,2
    --139270527(+) CACAGC/TGGCCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for SNAPC4 (139270029 - 139293249 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/23 variations for SNAPC4 (see all 23):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv509333CNV Insertion20534489
    nsv894367CNV Loss21882294
    nsv894364CNV Loss21882294
    nsv894366CNV Loss21882294
    nsv894294CNV Loss21882294
    nsv894365CNV Loss21882294
    dgv8390n71CNV Loss21882294
    nsv894359CNV Loss21882294
    dgv8389n71CNV Loss21882294
    dgv8386n71CNV Loss21882294


    Human Gene Mutation Database (HGMD): SNAPC4
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602777    OMIM disorders: --

    3 diseases for SNAPC4:    About MalaCards
    crohn's disease    hepatitis b    hepatitis


    SNAPC4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SNAPC4
    Human Genome Epidemiology (HuGE) Navigator: SNAPC4 (3 documents)

    Export disorders for SNAPC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNAPC4 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with SNAPC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. (PubMed id 9418884)1, 2, 3, 9 Wong M.W.... Hernandez N. (1998)
    2. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. (PubMed id 12621023)1, 2, 9 Hinkley C.S.... Henry R.W. (2003)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. A map of protein-protein contacts within the small nuclear RNA- activating protein complex SNAPc. (PubMed id 11056176)1, 2 Ma B. and Hernandez N. (2001)
    6. The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III. (PubMed id 17670747)1, 9 Gu L....Henry R.W. (2007)
    7. A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300. (PubMed id 22936669)1 Julia A....Marsal S. (2013)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    10. Meta-analysis identifies 29 additional ulcerative col itis risk loci, increasing the number of confirmed associations to 47. (PubMed id 21297633)1 Anderson C.A....Rioux J.D. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6621 HGNC: 11137 AceView: SNAPC4 Ensembl:ENSG00000165684 euGenes: HUgn6621
    ECgene: SNAPC4 H-InvDB: SNAPC4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNAPC4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SNAPC4 gene:
    Search GeneIP for patents involving SNAPC4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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