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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SNAPC3 Gene

protein-coding   GIFtS: 49
GCID: GC09P015412

small nuclear RNA activating complex, polypeptide 3, 50kDa

(Previous names: small nuclear RNA activating complex, polypeptide 3, 5...)
 Explore 1 disease affiliated with
SNAPC3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SNAPC3    

Aliases
for SNAPC3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Small Nuclear RNA Activating Complex, Polypeptide 3, 50kDa1 2     SNAPc 50 KDa Subunit2 3
SNAP501 2 3     SNAPc Subunit 32 3
PTFbeta1 2     SnRNA-Activating Protein Complex 50 KDa Subunit2 3
Proximal Sequence Element-Binding Transcription Factor Subunit Beta2 3     MGC1320111
Small Nuclear RNA-Activating Complex Polypeptide 32 3     MGC331241
PSE-Binding Factor Subunit Beta2 3     Small Nuclear RNA Activating Complex, Polypeptide 3, 50kD1
PTF Subunit Beta2 3     SnRNA-Activating Protein Complex Subunit 32

External Ids:    HGNC: 111361   Entrez Gene: 66192   Ensembl: ENSG000001649757   OMIM: 6023485   UniProtKB: Q929663   

Export aliases for SNAPC3 gene to outside databases

Previous GC identifers: GC09P015588 GC09P015404


Summaries
for SNAPC3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: SNPC3_HUMAN, Q92966
Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA
genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of
genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

Gene Wiki entry for SNAPC3


Genomic Views
for SNAPC3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008413.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SNAPC3 gene promoter:
         HFH-3   Sox5   ATF-2   STAT5A   HNF-3beta   FOXI1   Pax-3   SEF-1 (1)   Sox9   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SNAPC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SNAPC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22.3   Ensembl cytogenetic band:  9p22.3   HGNC cytogenetic band: 9p22.3

SNAPC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNAPC3 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P015412:  view genomic region     (about GC identifiers)

Start:
 15,422,702 bp from pter      End:
 15,465,951 bp from pter
Size:
 43,250 bases      Orientation:
 plus strand

Proteins
for SNAPC3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SNPC3_HUMAN, Q92966 (See protein sequence)
Recommended Name: snRNA-activating protein complex subunit 3  
Size: 411 amino acids; 46753 Da
Subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts
with SNAPC1
Subcellular location: Nucleus
Secondary accessions: D3DRI8 Q2VPI6 Q5T285

Explore the universe of human proteins at neXtProt for SNAPC3: NX_Q92966

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q92966

    • SNAPC3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001034786.1  
    ENSEMBL proteins: 
     ENSP00000370200   ENSP00000436699   ENSP00000432393   ENSP00000391832   ENSP00000370177  
    Reactome Protein details: Q92966
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: SNAPC3
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    Novus Biologicals SNAPC3 Protein
    Novus Biologicals SNAPC3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SNAPC3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS7715707
    GO:0005654nucleoplasm TAS--


    SNAPC3 for ontologies           About GeneDecksing



    SNAPC3 Antibody Products: 
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    Uscn ELISAs and CLIAs for SNAPC3

    Protein Domains /
    Families
    for SNAPC3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SNAPC3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR022042 snRNA-activating_su3

    Graphical View of Domain Structure for InterPro Entry Q92966

    ProtoNet protein and cluster: Q92966


    Function
    for SNAPC3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SNPC3_HUMAN, Q92966
    Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA
    genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of
    genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNAPC3
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SNAPC3:
    hsa-miR-548p hsa-miR-3660 hsa-miR-664 hsa-miR-3171 hsa-miR-3200-3p hsa-miR-186 hsa-miR-129-5p hsa-miR-4326
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNAPC3 (see all 7)
    OriGene shRNA RFP: SNAPC3
    OriGene siRNA: SNAPC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNAPC3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for SNAPC3

    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNAPC3 

    Cell Line
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    Search LifeMap BioReagents cell lines for SNAPC3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNAPC3

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--


    SNAPC3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SNAPC3:
     Decreased viability 


    Pathways & Interactions
    for SNAPC3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1RNA Polymerase III Transcription Initiation
    		RNA Polymerase III Transcription Initiation1.00
    		RNA Polymerase III Transcription Initiation From Type 3 Promoter0.80
    		RNA Polymerase III Transcription1.00
    		RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    		RNA Polymerase III Abortive And Retractive Initiation1.00
    2Transcription
    		Transcription1.00
    3Generic Transcription Pathway
    		Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/7        Reactome Pathways for SNAPC3 (see all 7)
        RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation From Type 3 Promoter
    Transcription
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
    RNA Polymerase III Transcription



    SNAPC3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SNAPC3

    5 Interacting proteins for SNAPC3 (Q929663) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RB1P064003I2D: score=3 
    SNAPC1Q165333I2D: score=3 
    MFAP1P550813I2D: score=2 
    ATG16L1Q676U53I2D: score=1 
    GRB2P629933I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006366transcription from RNA polymerase II promoter TAS7715707
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0009301snRNA transcription TAS7715707
    GO:0010467gene expression TAS--


    SNAPC3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SNAPC3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SNAPC3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SNAPC3
    1 Novoseek chemical compound relationship for SNAPC3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    s-napc 97.8 5 9003788 (2), 12486231 (1), 9418884 (1), 7715707 (1)

    Search CenterWatch for drugs/clinical trials and news about SNAPC3 / SNPC3 

    Transcripts
    for SNAPC3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SNAPC3 gene (2 alternative transcripts): 
    NM_003084.1  NM_001039697.1  

    Unigene Cluster for SNAPC3:

    Small nuclear RNA activating complex, polypeptide 3, 50kDa
    Hs.546299  [show with all ESTs]
    Unigene Representative Sequence: NM_001039697
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000380821(uc003zlt.3) ENST00000467062(uc011lmt.1 uc003zlu.3)
    ENST00000490969 ENST00000421710 ENST00000461041 ENST00000380799

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SNAPC3
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate SNAPC3:
    hsa-miR-548p hsa-miR-3660 hsa-miR-664 hsa-miR-3171 hsa-miR-3200-3p hsa-miR-186 hsa-miR-129-5p hsa-miR-4326
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SNAPC3 (see all 7)
    OriGene shRNA RFP: SNAPC3
    OriGene siRNA: SNAPC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SNAPC3
    Clone
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    GenScript: all cDNA clones in your preferred vector: SNAPC3 (NM_001039697)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SNAPC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNAPC3 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SNAPC3
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SNAPC3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SNAPC3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SNAPC3

    Additional cDNA sequence: 

    AK293310.1 BC036031.1 BC108743.1 BC121011.1 BC121012.1 U71300.1 

    15 DOTS entries:

    DT.100702470  DT.444204  DT.92339623  DT.95097682  DT.121199801  DT.92441357  DT.95150644  DT.412125 
    DT.452382  DT.100673633  DT.100736784  DT.121199984  DT.92052179  DT.121199977  DT.95131118 

    24/194 AceView cDNA sequences (see all 194):

    BM474531 BF194913 BQ224037 AA446555 BC014985 BM693308 CR624760 BF477373 
    CA392854 CA430062 BM799760 AW069569 AI392889 C00670 AA912627 Z42500 
    BQ004139 F02046 CA396742 AA149136 AI363284 CD616242 AW383264 AL041974 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SNAPC3    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
    SP1:                                                        -                 -         
    SP2:                                                        -                           
    SP3:              -                 -     -                                             
    SP4:                                                                                    


    ECgene alternative splicing isoforms for SNAPC3

    Expression
    for SNAPC3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SNAPC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAAAATCAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SNAPC3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Neural TubeNeural TubeSpinal Neural Tube CellsNeural Ectoderm
    EyeRetinaEye
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SNAPC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SNAPC3

    SOURCE GeneReport for Unigene cluster: Hs.546299
        SABiosciences Custom PCR Arrays for SNAPC3
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNAPC3

    Orthologs
    for SNAPC3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SNAPC3 gene from 9/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Snapc31 , 5 small nuclear RNA activating complex, polypeptide 31, 5 84.4(n)1
    86.21(a)1    		   4 (39.46 cM)5
    776341  NM_029949.31  NP_084225.11 
     834177245 
    chicken
    (Gallus gallus)    		 Aves SNAPC31 small nuclear RNA activating complex, polypeptide 3, more 70.61(n)
    70.43(a)    		   768769  XM_001231674.1  XP_001231675.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SNAPC36
    		 --
    		 68(a)
    		 1 ↔ 1
    		 2(34996725-35025403)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.237382 Xenopus laevis transcribed sequence with weak similarity more 74.19(n)    CB201395.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc562952 similar to small nuclear RNA activating complex, polypeptide more 75.72(n)   394090  BC050516.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Pbp496
    		 PSEA-binding protein 49kD
    		 22(a)
    		 1 ↔ 1
    		 2R(4016859-4018837)
    worm
    (Caenorhabditis elegans)    		 Secernentea T02C12.26
    Y48G1BM.16
    (see all 4)    		 Protein Y48G1BM.1
    (see all 4)    		 19(a)
    17(a)
    (see all 4)    		 many → 1
    many → 1
    (see all 4)    		 III(4020041-4021854)
    I(252118-254129)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SRD26
    		 snRNA activating complex family protein
    		 22(a)
    		 1 ↔ 1
    		 1(10038038-10041544)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 expressed protein
    		 17(a)
    		 1 ↔ 1
    		 1(39772048-39775744)


    ENSEMBL Gene Tree for SNAPC3 (if available)
    TreeFam Gene Tree for SNAPC3 (if available) 

    Paralogs
    for SNAPC3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for SNAPC3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/899 NCBI SNPs in SNAPC3 are shown (see all 899)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs766835001,2
    		--15415589(+) TTTTTA/TAAAAA 1 -- int10--------
    rs101179681,2
    		C,F,A,H,--15420805(+) GTTTCG/TAAGAC 1 -- us2k123Minor allele frequency- T:0.43NS EA NA WA CSA 2315
    rs1855612861,2
    		--15420932(+) ATATGC/TGGTTG 1 -- us2k10--------
    rs1434515521,2
    		--15421045(+) CATGAA/GTGTTC 1 -- us2k10--------
    rs1899730971,2
    		--15421143(+) AAGTAC/GTGACA 1 -- us2k10--------
    rs13972141,2
    		C,F,H,--15421170(+) TGAACC/GTGTTA 1 -- us2k124Minor allele frequency- N:0.00NS EA NA WA CSA 1424
    rs1812283471,2
    		--15421195(+) CCAAGC/TTACCA 1 -- us2k10--------
    rs1862014161,2
    		--15421198(+) AGTTAC/TCAGGG 1 -- us2k10--------
    rs1467482081,2
    		--15421204(+) CAGGGA/CAAATC 1 -- us2k10--------
    rs1401276561,2
    		--15421245(+) CCTCCA/TCAGAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNAPC3 (15422702 - 15465951 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SNAPC3: --

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    Disorders / Diseases
    for SNAPC3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SNAPC3 for disorders           About GeneDecksing

    OMIM gene information: 602348    OMIM disorders: --

    1 disease for SNAPC3:    About MalaCards
    retinoblastoma


    Export disorders for SNAPC3 gene to outside databases

    Publications
    for SNAPC3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SNAPC3 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with SNAPC3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of SNAP50, a subunit of the snRNA- activating protein complex SNAPc. (PubMed id 9003788)1, 2, 3, 9 Henry R.W.... Hernandez N. (1996)
    2. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. (PubMed id 12621023)1, 2, 9 Hinkley C.S.... Henry R.W. (2003)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A map of protein-protein contacts within the small nuclear RNA- activating protein complex SNAPc. (PubMed id 11056176)1, 2 Ma B. and Hernandez N. (2001)
    6. Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III. (PubMed id 8816454)1, 2 Bai L.... Roeder R.G. (1996)
    7. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. (PubMed id 7715707)1, 9 Henry R.W.... Hernandez N. (1995)
    8. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    9. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    External Searches for SNAPC3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    Genome Databases showing SNAPC3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6619 HGNC: 11136 AceView: SNAPC3 Ensembl:ENSG00000164975 euGenes: HUgn6619
    ECgene: SNAPC3 H-InvDB: SNAPC3

    Other Databases showing SNAPC3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SNAPC3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SNAPC3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SNAPC3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SNAPC3 gene:
    Search GeneIP for patents involving SNAPC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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