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SNAPC1 Gene

protein-coding   GIFtS: 54
GCID: GC14P062229

Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa

(Previous names: small nuclear RNA activating complex, polypeptide 1, 43kD)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Small Nuclear RNA Activating Complex, Polypeptide 1, 43kDa1 2     SNAPc 43 KDa Subunit2 3
SNAP432 3 5     SNAPc Subunit 12 3
Proximal Sequence Element-Binding Transcription Factor Subunit Gamma2 3     SnRNA-Activating Protein Complex 43 KDa Subunit2 3
Small Nuclear RNA-Activating Complex Polypeptide 12 3     Small Nuclear RNA Activating Complex, Polypeptide 1, 43kD1
PSE-Binding Factor Subunit Gamma2 3     PTFgamma2
PTF Subunit Gamma2 3     SnRNA-Activating Protein Complex Subunit 12

External Ids:    HGNC: 111341   Entrez Gene: 66172   Ensembl: ENSG000000236087   OMIM: 6005915   UniProtKB: Q165333   

Export aliases for SNAPC1 gene to outside databases

Previous GC identifers: GC14U990055 GC14P056022 GC14P060219 GC14P061298 GC14P042392


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SNAPC1 Gene:
SNAPC1 (small nuclear RNA activating complex, polypeptide 1, 43kDa) is a protein-coding gene.

UniProtKB/Swiss-Prot: SNPC1_HUMAN, Q16533
Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear
RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2
types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

Gene Wiki entry for SNAPC1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the SNAPC1 gene promoter:
         TBP   HOXA9   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   Cdc5   POU3F2   POU2F1   POU2F1a   POU2F1b   POU2F1c   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSNAPC1 promoter sequence
   Search Chromatin IP Primers for SNAPC1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SNAPC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q22   Ensembl cytogenetic band:  14q23.2   HGNC cytogenetic band: 14q22

SNAPC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SNAPC1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P062229:  view genomic region     (about GC identifiers)

Start:
62,229,075 bp from pter      End:
62,263,146 bp from pter
Size:
34,072 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SNPC1_HUMAN, Q16533 (See protein sequence)
Recommended Name: snRNA-activating protein complex subunit 1  
Size: 368 amino acids; 42994 Da
Subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC1
interacts with SNAPC3, SNAPC4 and TBP

Explore the universe of human proteins at neXtProt for SNAPC1: NX_Q16533

Explore proteomics data for SNAPC1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys142
  • Modification sites at PhosphoSitePlus

  • See SNAPC1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003073.1  
    ENSEMBL proteins: 
     ENSP00000216294  
    Reactome Protein details: Q16533

    SNAPC1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for SNAPC1

     
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    Search eBioscience for ELISAs for SNAPC1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019188 SNAPc_SNAP43

    Graphical View of Domain Structure for InterPro Entry Q16533

    ProtoNet protein and cluster: Q16533


    Find genes that share domains with SNAPC1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SNPC1_HUMAN, Q16533
    Function: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear
    RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2
    types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box

         Genatlas biochemistry entry for SNAPC1:
    small nuclear activating protein complex,polypeptide 1,43kDa,TBP associated factor (TAF) binding to the proximal
    sequence element PSE,required for transcription of SNRN genes by polymerases II and III,soluble N
    ethylmaleimide-sensitive factor-attachment protein receptor,SNARE protein

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
         
    Find genes that share ontologies with SNAPC1           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for SNAPC1:
     G0/1 arrest  Increased S DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SNAPC1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SNAPC1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SNAPC1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SNAPC1:
    hsa-mir-375 (MIRT019697)

    Block miRNA regulation of human, mouse, rat SNAPC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNAPC1 (see all 22):
    hsa-miR-136 hsa-miR-137 hsa-miR-429 hsa-miR-25 hsa-miR-373* hsa-miR-374c hsa-miR-298 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidSNAPC1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNAPC1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SNPC1_HUMAN, Q16533: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion2
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--

    Find genes that share ontologies with SNAPC1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SNAPC1 About    
    See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation0.88
    RNA Polymerase III Transcription0.88
    RNA Polymerase III Abortive And Retractive Initiation0.88
    RNA Polymerase III Transcription Initiation From Type 3 Promoter0.80
    2RNA Polymerase I Promoter Opening
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.73
    3Gene Expression
    Gene Expression0.40


    Find genes that share SuperPaths with SNAPC1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for SNAPC1
        RNA Polymerase III Transcription Initiation From Type 3 Promoter
    RNA Polymerase III Abortive And Retractive Initiation


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SNAPC1
    Interactions:

        GeneGlobe Interaction Network for SNAPC1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SNAPC1 (Q165333 ENSP000002162944) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNAPC4Q5SXM23, ENSP000002985324I2D: score=3 STRING: ENSP00000298532
    RHOXF2Q9BQY43, ENSP000003604414I2D: score=1 STRING: ENSP00000360441
    SNAPC5O759713, ENSP000003195974I2D: score=1 STRING: ENSP00000319597
    TBPP202263, ENSP000002303544I2D: score=1 STRING: ENSP00000230354
    TRIM29Q141343, ENSP000003431294I2D: score=1 STRING: ENSP00000343129
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0010467gene expression TAS--

    Find genes that share ontologies with SNAPC1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SNAPC1 (SNPC1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SNAPC1 gene: 
    NM_003082.3  

    Unigene Cluster for SNAPC1:

    Small nuclear RNA activating complex, polypeptide 1, 43kDa
    Hs.179312  [show with all ESTs]
    Unigene Representative Sequence: NM_003082
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000216294(uc001xft.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat SNAPC1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SNAPC1 (see all 22):
    hsa-miR-136 hsa-miR-137 hsa-miR-429 hsa-miR-25 hsa-miR-373* hsa-miR-374c hsa-miR-298 hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidSNAPC1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SNAPC1
    Predesigned siRNA for gene silencing in human, mouse, rat SNAPC1
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SNAPC1 (NM_003082)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SNAPC1
    Primer
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    OriGene qPCR primer pairs and template standards for SNAPC1
    OriGene qSTAR qPCR primer pairs in human, mouse for SNAPC1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SNAPC1
      QuantiTect SYBR Green Assays in human, mouse, rat SNAPC1
      QuantiFast Probe-based Assays in human, mouse, rat SNAPC1

    Additional mRNA sequence: 

    AK314933.1 BC014984.1 BC019038.2 U44754.1 Z47542.1 

    11 DOTS entries:

    DT.100836210  DT.107631  DT.100723489  DT.100793048  DT.120747079  DT.100793047  DT.100793050  DT.120747077 
    DT.91668791  DT.100773287  DT.100805899 

    Selected AceView cDNA sequences (see all 611):

    BG108056 AW674966 AA789181 AU130520 CD657654 BQ573997 BU753719 CB990343 
    BQ008637 BP361393 AW630580 AU076780 AI826048 BM999426 AW304738 AW964525 
    AI754970 BP360572 BX096501 BM855763 BU152549 BM976985 BQ009915 BG678971 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for SNAPC1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                                                                              
    SP2:                          -                                                   


    ECgene alternative splicing isoforms for SNAPC1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SNAPC1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATTTCAGT
    SNAPC1 Expression
    About this image


    SNAPC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Endothelium (Cardiovascular System)
             Extraembryonic Angioblasts Extraembryonic Capillary Plexus
     
     Extraembryonic Mesoderm (Extraembryonic Tissues)
             Extraembryonic Angioblasts Extraembryonic Capillary Plexus
     
     Testis (Reproductive System)
    SNAPC1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SNAPC1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.179312
        Custom PCR Arrays for SNAPC1
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SNAPC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SNAPC1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Snapc11 , 5 small nuclear RNA activating complex, polypeptide 11, 5 80.51(n)1
    78.69(a)1
      12 (32.00 cM)5
    756271  NM_178392.41  NP_848479.11 
     739645305 
    chicken
    (Gallus gallus)
    Aves SNAPC11 small nuclear RNA activating complex, polypeptide 1, more 66.02(n)
    60(a)
      423517  XM_004936441.1  XP_004936498.1 
    lizard
    (Anolis carolinensis)
    Reptilia SNAPC16
    small nuclear RNA activating complex, polypeptide ...
    44(a)
    1 ↔ 1
    1(3165631-3179050)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.131702 Xenopus laevis transcribed sequence with weak similarity more 75.35(n)    BU913681.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc554752 similar to small nuclear RNA activating complex, polypeptide more 71.91(n)   393224  BC048040.1 


    ENSEMBL Gene Tree for SNAPC1 (if available)
    TreeFam Gene Tree for SNAPC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SNAPC1 gene

    Find genes that share paralogs with SNAPC1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for SNAPC1
    PGOHUM00000243816


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SNAPC1 (see all 921)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1386636611,2
    --62227098(+) CCCAGC/TCTCCC 1 -- us2k10--------
    rs790960911,2
    C,F--62227126(+) GGCACA/GCGCCA 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs770828101,2
    C--62227268(+) CACTGA/CGCCCA 1 -- us2k10--------
    rs1170076561,2
    F--62227420(+) AGATTC/TGGTCT 1 -- us2k11Minor allele frequency- T:0.01NA 120
    rs1473876531,2
    --62227464(+) GATCTC/GGGCTC 1 -- us2k10--------
    rs1379908601,2
    C--62227556(+) ACTACA/GGGTGT 1 -- us2k10--------
    rs1174755061,2
    F--62227772(+) GTAATG/ATTCTG 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs116260421,2
    H--62228017(+) tactaA/Taaata 1 -- us2k10--------
    rs341916561,2
    C--62228036(+) ACAAAC/ACAAAA 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1494769331,2
    --62228115(+) TTGAAC/TTCGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SNAPC1 (62229075 - 62263146 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SNAPC1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1301CNV Insertion18451855
    nsv902008CNV Loss21882294
    nsv1300CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SNAPC1
    DNA2.0 Custom Variant and Variant Library Synthesis for SNAPC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600591    OMIM disorders: --


    Find genes that share disorders with SNAPC1           About GenesLikeMe


    Export disorders for SNAPC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SNAPC1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with SNAPC1)
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    1. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. (PubMed id 12621023)1, 2, 9 Hinkley C.S.... Henry R.W. (J. Biol. Chem. 2003)
    2. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. (PubMed id 7715707)1, 2, 9 Henry R.W.... Hernandez N. (Nature 1995)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. A map of protein-protein contacts within the small nuclear RNA- activating protein complex SNAPc. (PubMed id 11056176)1, 2 Ma B. and Hernandez N. (J. Biol. Chem. 2001)
    5. The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR. (PubMed id 9644240)1, 3 Maeng J.H. and Yoon J.B. (J. Biochem. 1998)
    6. Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. (PubMed id 8524284)1, 2 Yoon J.B. and Roeder R.G. (Mol. Cell. Biol. 1996)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. Requirement for SNAPC1 in transcriptional responsiveness to diverse extracellular signals. (PubMed id 22966203)1 Baillat D....Shiekhattar R. (Mol. Cell. Biol. 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6617 HGNC: 11134 AceView: HIF1AandSNAPC1 Ensembl:ENSG00000023608 euGenes: HUgn6617
    ECgene: SNAPC1 H-InvDB: SNAPC1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SNAPC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SNAPC1 gene:
    Search GeneIP for patents involving SNAPC1

    GeneCards and IP:
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