Aliases for SMYD3 Gene
External Ids for SMYD3 Gene
Previous HGNC Symbols for SMYD3 Gene
Previous GeneCards Identifiers for SMYD3 Gene
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for SMYD3 Gene
SMYD3 (SET And MYND Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD1.
UniProtKB/Swiss-Prot for SMYD3 Gene
Histone methyltransferase. Specifically methylates Lys-4 and Lys-5 of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5-CCCTCC-3 or 5-GAGGGG-3 sequences.