SMYD2 Gene
protein-coding GIFtS: 54
GCID: GC01P214454
|
|
SET and MYND domain containing 2
| |
Aliases
for SMYD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SET And MYND Domain Containing 21 2 | | SET And MYND Domain-Containing Protein 22 3 | | HSKM-B1 2 3 | | N-Lysine Methyltransferase SMYD22 | | KMT3C1 2 3 | | Zinc Finger, MYND Domain Containing 142 | | ZMYND141 2 | | EC 2.1.1.-3 | | Histone Methyltransferase SMYD22 3 | | EC 2.1.1.433 | | Lysine N-Methyltransferase 3C2 3 | | |
Export aliases for SMYD2 gene to outside databasesPrevious GC identifers: GC01P211070 GC01P211511 GC01P210842 GC01P212521 GC01P185129 |
Summaries
for SMYD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SMYD2:
SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 (PubMed16805913)).(supplied by OMIM, Nov 2008)
UniProtKB/Swiss-Prot: SMYD2_HUMAN, Q9NRG4Function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specificallymethylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferaseactivity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading todecreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates'Lys-860' of RB1/RB
|
Genomic Views
for SMYD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SMYD2 gene promoter:
TBP GR NRSF form 1 GR-beta Pax-2 Pax-2a SRY Pax-2b TFIID GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMYD2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMYD2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q32.3 Ensembl cytogenetic band: 1q32.3 HGNC cytogenetic band: 1q32.3SMYD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P214454: view genomic region
(about GC identifiers)
Start:
|
214,454,445 bp from pter |
End:
|
214,510,477 bp from pter |
Size:
|
56,033 bases |
Orientation:
|
plus strand |
|
Proteins
for SMYD2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SMYD2_HUMAN, Q9NRG4 (See
protein sequence)Recommended Name: N-lysine methyltransferase SMYD2 Size: 433 amino acids; 49688 Da
Subunit: Interacts with RNA polymerase II and HELZ. Interacts with SIN3A and HDAC1 (By similarity). Interacts (viaMYND-type zinc finger) with EPB41L3. Interacts (via SET domain) with p53/TP53. Interacts with RB1 and HSP90AA1
Subcellular location: Cytoplasm, cytosol (By similarity). Nucleus (By similarity)
6/7 PDB 3D structures from  and Proteopedia  for SMYD2 (see all 7):3RIB (3D)
3S7B (3D)
3S7D (3D)
3S7F (3D)
3S7J (3D)
3TG4 (3D)
Secondary accessions: B2R9P9 Q4V765 Q5VSH9 Q96AI4Explore the universe of human proteins at neXtProt for SMYD2: NX_Q9NRG4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NRG4
SMYD2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_064582.2
ENSEMBL proteins: ENSP00000355924 ENSP00000409822 ENSP00000388682
Human Recombinant Protein Products for SMYD2:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SMYD2 for ontologies About GeneDecksing
SMYD2 Antibody Products:
Assay Products for SMYD2: |
Protein
Domains /
Families
for SMYD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SMYD2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NRG4ProtoNet protein and cluster: Q9NRG4 2 Blocks protein families: IPB001214 Nuclear protein SET IPB002893 Zn-finger
UniProtKB/Swiss-Prot: SMYD2_HUMAN, Q9NRG4Similarity: Contains 1 MYND-type zinc fingerSimilarity: Contains 1 SET domain |
Function
for SMYD2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SMYD2_HUMAN, Q9NRG4Function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specificallymethylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferaseactivity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading todecreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates'Lys-860' of RB1/RBCatalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine +N(6)-methyl-L-lysine-[histone]Induction: Expression is repressed by CEBPA Enzyme Numbers (IUBMB): EC 2.1.1.431 EC 2.1.1.-1
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
SMYD2 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for SMYD2:
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Smyd2):
SMYD2 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SMYD2 (NM_020197) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMYD2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMYD2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMYD2 |
|
Pathways & Interactions
for SMYD2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | p53 pathway | | | 2 | Chromatin Regulation / Acetylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for SMYD2
1  BioSystems Pathway for SMYD2
SMYD2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SMYD2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/35 Interacting proteins for SMYD2 (Q9NRG43 ENSP000003559244) via UniProtKB, MINT, STRING, and/or I2D (see all 35)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IMP | 17108971 | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0008285 | negative regulation of cell proliferation |
ISS | -- | | GO:0010452 | histone H3-K36 methylation |
-- | -- | | GO:0018026 | peptidyl-lysine monomethylation |
IDA | -- |
SMYD2 for ontologies About GeneDecksing
|
Drugs & Compounds
for SMYD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMYD2
Search CenterWatch for drugs/clinical trials and news about SMYD2
|
Transcripts
for SMYD2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SMYD2 gene: NM_020197.2 Unigene Cluster for SMYD2: SET and MYND domain containing 2 Hs.66170 [show with all ESTs]Unigene Representative Sequence: BC0685117 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000491455(uc021pix.1 uc009xdl.1) ENST00000471645 ENST00000460580(uc021piw.1)
ENST00000366957 ENST00000484459 ENST00000416415 ENST00000415093
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SMYD2 (NM_020197) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMYD2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMYD2 |
Additional cDNA sequence: AF070592.1 AF226053.1 AK090571.1 AK091590.1 AK098683.1 AK313868.1 BC017080.2 BC028104.1 BC039890.1 BC057793.1 BC068511.1 BC098133.1 BC098276.1 BC098335.1 13 DOTS entries: DT.446799 DT.95183994 DT.100032982 DT.91800781 DT.100819009 DT.100033037 DT.100819010 DT.40250753 DT.97858902 DT.100809597 DT.75140314 DT.444352 DT.91924949 24/213 AceView cDNA sequences (see all 213): CA313122 CR617804 CF552077 H98065 CR592315 AI692922 AI377234 BM740370 CA434890 CR589978 BC028104 CR613242 BM466219 BM739135 AI627479 AK098683 CA411809 AA804764 BC039890 R88886 AW519313 CR622801 BC017080 AI708404
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SMYD2 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | - | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SMYD2
|
Expression
for SMYD2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SMYD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTCTTGTAA
About this image
See SMYD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SMYD2
SOURCE GeneReport for Unigene cluster: Hs.66170
SABiosciences Custom PCR Arrays for SMYD2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMYD2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SMYD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMYD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMYD2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMYD2 |
Orthologs
for SMYD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SMYD2 gene from 8/27 species (see all 27) About this table
ENSEMBL Gene Tree for SMYD2 (if available)
TreeFam Gene Tree for SMYD2 (if available) |
Paralogs
for SMYD2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SMYD2 gene
- SMYD42 SMYD12 SMYD32
3 SIMAP similar genes for SMYD2 using alignment to 5 protein entries: SMYD2_HUMAN (see all proteins):SMYD1 DKFZp313O0925 SMYD3
SMYD2 for paralogs About GeneDecksing
|
Genomic Variants
for SMYD2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SMYD2 (214454445 - 214510477 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SMYD2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMYD2 |
|
Disorders
/ Diseases
for SMYD2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SMYD2 for disorders About GeneDecksing
OMIM gene information: 610663
OMIM disorders: --
12  diseases for SMYD2: About MalaCardsesophageal squamous cell carcinoma squamous cell carcinoma papillary thyroid carcinoma folliculitis
thyroid carcinoma thyroiditis homocysteine esophagitis
carcinoma retinoblastoma colorectal cancer malaria
Human Genome Epidemiology (HuGE) Navigator: SMYD2 (1 document)
Export disorders for SMYD2 gene to outside databases
|
Publications
for SMYD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SMYD2 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with SMYD2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Methylation of the retinoblastoma tumor suppressor by SMYD2. (PubMed id 20870719)1, 2 Saddic L.A.... Sage J. (2010)
- The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. (PubMed id 18065756)1, 2 Abu-Farha M....Figeys D. (2008)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Repression of p53 activity by Smyd2-mediated methylation. (PubMed id 17108971)1, 2 Huang J.... Berger S.L. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- RB1 methylation by SMYD2 enhances cell cycle progression through an increase of RB1 phosphorylation. (PubMed id 22787429)1 Cho H.S.... Hamamoto R. (2012)
- Proteomic analyses of the SMYD family interactomes ide ntify HSP90 as a novel target for SMYD2. (PubMed id 22028380)1 Abu-Farha M....Couture J.F. (2011)
- Differential expression of a set of genes in follicul ar and classic variants of papillary thyroid carcinoma. (PubMed id 21509594)1 Igci Y.Z....Demiryurek A.T. (2011)
- Structural basis of substrate methylation and inhibit ion of SMYD2. (PubMed id 21782458)1 Ferguson A.D....Keen N. (2011)
- Structure of human SMYD2 protein reveals the basis of p53 tumor suppressor methylation. (PubMed id 21880715)1 Wang L....Zhao K. (2011)
|
External Searches for SMYD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SMYD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SMYD2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SMYD2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SMYD2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SMYD2 gene:
Search GeneIP for patents involving SMYD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SMYD2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SMYD2 | | OriGene shRNA RFP for SMYD2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMYD2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMYD2 | | | OriGene Protein Over-expression Lysate for SMYD2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SMYD2 | | OriGene 3'-UTR Clone for SMYD2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SMYD2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMYD2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMYD2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMYD2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMYD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMYD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMYD2 |
| |
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| | Antibodies & Assays for SMYD2 |
| | | | Search Tocris compounds for SMYD2 |
| |  |  |  |  | | | | |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMYD2 |
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