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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SMYD1 Gene

protein-coding GIFtS: 52
GCID: GC02P088367

SET and MYND domain containing 1

Explore 4 diseases affiliated with
SMYD1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
SET And MYND Domain Containing 1¹ ²		ZMYND18²
BOP¹ ²		CD8 Beta Opposite²
KMT3D¹ ²		SET And MYND Domain-Containing Protein 1²
ZMYND22¹ ²		Zinc Finger, MYND Domain Containing 18²

External Ids:	HGNC: 20986¹	Entrez Gene: 150572²	Ensembl: ENSG00000115593⁷	OMIM: 606846⁵	UniProtKB: Q8NB12³

Export aliases for SMYD1 gene to outside databases

Previous GC identifers: GC02P088252 GC02P088269 GC02P088206 GC02P087289

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SMYD1_HUMAN, Q8NB12

Function: Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis

(By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SMYD1 gene promoter:
HOXA9 HOXA9B Elk-1 POU6F1 (c2) GATA-1 MEF-2A HOXA5 Meis-1a aMEF-2 Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SMYD1 promoter sequence

Search SABiosciences Chromatin IP Primers for SMYD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMYD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11.2 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p11.1

SMYD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SMYD1 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P088367: view genomic region (about GC identifiers)

Start:	88,367,299 bp from pter	End:	88,412,906 bp from pter
Size:	45,608 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SMYD1_HUMAN, Q8NB12 (See protein sequence)

Recommended Name: SET and MYND domain-containing protein 1

Size: 490 amino acids; 56617 Da

Subunit: Interacts with HDAC1, HDAC2 and HDAC3 (By similarity)

Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)

Secondary accessions: A0AV30 A6NE13

Explore the universe of human proteins at neXtProt for SMYD1: NX_Q8NB12

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NB12

SMYD1 Protein expression data from MOPED and PaxDb: --

REFSEQ proteins: NP_938015.1

ENSEMBL proteins:

ENSP00000393453 ENSP00000407888 ENSP00000387482

Human Recombinant Protein Products:

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	Novus Biologicals SMYD1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SMYD1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	IEA	--

SMYD1 for ontologies About GeneDecksing

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	GenScript Custom Assay Services for SMYD1
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	Uscn ELISAs and CLIAs for SMYD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SMYD1 for domains About GeneDecksing

2 InterPro domains/families:

IPR002893 Znf_MYND

IPR001214 SET_dom

Graphical View of Domain Structure for InterPro Entry Q8NB12

ProtoNet protein and cluster: Q8NB12

2 Blocks protein families:

IPB001214 Nuclear protein SET

IPB002893 Zn-finger

UniProtKB/Swiss-Prot: SMYD1_HUMAN, Q8NB12

Similarity: Contains 1 MYND-type zinc finger

Similarity: Contains 1 SET domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SMYD1_HUMAN, Q8NB12

Function: Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis

(By similarity)

miRNA Products:		OriGene 3'-UTR Clone: SMYD1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SMYD1
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SMYD1 (see all 12):
		hsa-miR-3678-3p hsa-miR-1298 hsa-miR-765 hsa-miR-3120-3p hsa-miR-888 hsa-miR-373* hsa-miR-664 hsa-miR-4261

		SwitchGear 3'UTR luciferase reporter plasmid: SMYD1 3' UTR sequence

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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SMYD1

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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Search LifeMap BioReagents cell lines for SMYD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMYD1

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0003714	transcription corepressor activity	IEA	--
GO:0005515	protein binding	--	--
GO:0008270	zinc ion binding	IEA	--

SMYD1 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-out Smyd1^tm1Dsr for SMYD1
     6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Smyd1):

cardiovascular system	cellular	embryogenesis	growth/size	mortality/aging
muscle

SMYD1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Heart Development

Heart Development

1.00

1 BioSystems Pathway for SMYD1

Heart Development

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SMYD1

3 Interacting proteins for SMYD1 (Q8NB12³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HDAC3	O15379³	I2D: score=2
HDAC1	Q13547³	I2D: score=1
HDAC2	Q92769³	I2D: score=1

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006338	chromatin remodeling	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0007507	heart development	IEA	--
GO:0010831	positive regulation of myotube differentiation	IDA	19783823
GO:0045663	positive regulation of myoblast differentiation	IDA	19783823

SMYD1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SMYD1
Search CenterWatch for drugs/clinical trials and news about SMYD1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SMYD1 gene:

NM_198274.3

Unigene Cluster for SMYD1:

SET and MYND domain containing 1

Hs.516176 [show with all ESTs]

Unigene Representative Sequence: NM_198274

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000419482(uc002ssq.2 uc002ssr.3 uc002sss.3) ENST00000444564

ENST00000438570 ENST00000468008

miRNA Products:		OriGene 3'-UTR Clone: SMYD1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SMYD1
		8/12 QIAGEN miScript miRNA Assays for microRNAs that regulate SMYD1 (see all 12):
		hsa-miR-3678-3p hsa-miR-1298 hsa-miR-765 hsa-miR-3120-3p hsa-miR-888 hsa-miR-373* hsa-miR-664 hsa-miR-4261

		SwitchGear 3'UTR luciferase reporter plasmid: SMYD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMYD1 (see all 7) OriGene shRNA RFP: SMYD1 OriGene siRNA: SMYD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMYD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD1 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMYD1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SMYD1 (NM_198274)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SMYD1
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMYD1

Additional cDNA sequence:

AF086123.1 AK022290.1 AK091724.1 AL832035.1 AY518933.1 AY518934.1 BC017915.1 BC126191.1

BX647878.1

4 DOTS entries:

DT.306345 DT.454717 DT.100747244 DT.120946134

24/65 AceView cDNA sequences (see all 65):

AA248334 AI078564 AI079318 BX500817 AI004011 AU147602 AK091724 AU121872

BM722342 BF060984 BF790590 CF552718 AA716121 AI420970 W95588 AI014299

AJ572108 BX647878 BX103184 AI015235 BQ918532 AX747145 NM_198274 F30640

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for SMYD1 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12
SP1:					-
SP2:																	-
SP3:
SP4:					-				-		-		-		-		-		-		-		-		-		-		-

ECgene alternative splicing isoforms for SMYD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SMYD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAACTGTATT

About this image

SMYD1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Myocardium

Primitive Heart Tube Cells

Myocardium

Limb

Forelimb Myotome

Limb Muscle Progenitor Cells

Skeletal Muscle

Heart

Heart Tube

Heart

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

DKK1-induced cells (Derivation of cardio...)

Cardiomyocyte-like progenitor cells (Derivation of cardio...)

Genevestigator expression for SMYD1

SOURCE GeneReport for Unigene cluster: Hs.516176

SABiosciences Custom PCR Arrays for SMYD1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMYD1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMYD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SMYD1 gene from 8/26 species (see all 26) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SMYD1¹	SET and MYND domain containing 1	78.69(n) 82.06(a)		373960 NM_204155.1 NP_989486.1
lizard (Anolis carolinensis)	Reptilia	SMYD1⁶	--	81(a)	1 ↔ 1	6(59317803-59360113)
African clawed frog (Xenopus laevis)	Amphibia	Xl.1817²	Xenopus laevis transcribed sequence with weak similarity more	77.51(n)		BJ073212.1
zebrafish (Danio rerio)	Actinopterygii	57046161²	--	78.48(n)		57046161
fruit fly (Drosophila melanogaster)	Insecta	Bzd⁶	Buzidau	21(a)	1 → many	X(2500712-2502700)
worm (Caenorhabditis elegans)	Secernentea	set-18⁶ set-14⁶ (see all 4)	SET domain-containing protein 14 (see all 4)	18(a) 18(a) (see all 4)	many ↔ many many ↔ many (see all 4)	I(10590709-10593951) II(10793516-10796240)
thale cress (Arabidopsis thaliana)	eudicotyledons	SDG37⁶	histone-lysine N-methyltransferase ASHR1	21(a)	possible ortholog	2(7773328-7776683)
rice (Oryza sativa)	Liliopsida	--	zinc finger protein, putative, expressed	21(a)	possible ortholog	3(28301394-28305323)

ENSEMBL Gene Tree for SMYD1 (if available)
TreeFam Gene Tree for SMYD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SMYD1 gene

SMYD4² SMYD2² SMYD3²

3 SIMAP similar genes for SMYD1 using alignment to 4 protein entries: SMYD1_HUMAN (see all proteins):

DKFZp313O0925 SMYD2 SMYD3

SMYD1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11891123^1,2	C,F,H,	--	88365338(+)	`GTCTCA/GATCTC`	1	--	us2k¹		6		NA	14
rs142139757^1,2		--	88365414(+)	`CCGGCC/TTCTTT`	1	--	us2k¹		0	--	--	--	--
rs188241574^1,2		--	88365516(+)	`AAGTTA/GTTTTG`	1	--	us2k¹		0	--	--	--	--
rs151157415^1,2		--	88365534(+)	`GTGTAC/TATCAG`	1	--	us2k¹		0	--	--	--	--
rs192258756^1,2		--	88365580(+)	`GTATTC/GTTACC`	1	--	us2k¹		0	--	--	--	--
rs184837112^1,2		--	88366208(+)	`CCTGGC/TAGCAG`	1	--	us2k¹		0	--	--	--	--
rs149176897^1,2	C,	--	88366462(+)	`TCTTA-/TTA TTTATTTATT`	1	--	us2k¹		0	--	--	--	--
rs60121022^1,2	C	--	88366494(+)	`TTATT-/TAT TTATTAATTT`	1	--	us2k¹		1		NA	2
rs189609572^1,2		--	88366529(+)	`GTCGCC/TCAGGC`	1	--	us2k¹		0	--	--	--	--
rs191405507^1,2		--	88366556(+)	`GATCTC/TGGCTC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SMYD1 (88367299 - 88412906 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SMYD1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMYD1

DNA2.0 Custom Variant and Variant Library Synthesis for SMYD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SMYD1 for disorders           About GeneDecksing

OMIM gene information: 606846    OMIM disorders: --

4 diseases for SMYD1:    About MalaCards

axenfeld-rieger syndrome hypoplastic left heart syndrome tetralogy of fallot malaria

2 diseases from the University of Copenhagen DISEASES database for SMYD1:

Axenfeld-Rieger syndrome Hypoplastic left heart syndrome

Human Genome Epidemiology (HuGE) Navigator: SMYD1 (1 document)

Export disorders for SMYD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SMYD1 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SMYD1)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. (PubMed id 11923873)^{1, 3} Gottlieb P.D....Srivastava D. (2002)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin. (PubMed id 19783823)¹ Li D....Liu M. (2009)
Hepatoma-derived growth factor represses SET and MYND domain containing 1 gene expression through interaction with C-terminal binding protein. (PubMed id 19162039)¹ Yang J. and Everett A.D. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)² Hillier L.W....Wilson R.K. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
m-Bop, a repressor protein essential for cardiogenesis, interacts with skNAC, a heart- and muscle-specific transcription factor. (PubMed id 12011100)¹ Sims R.J....Gottlieb P.D. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 150572	HGNC: 20986	AceView: SMYD1	Ensembl:ENSG00000115593	euGenes: HUgn150572
ECgene: SMYD1	H-InvDB: SMYD1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SMYD1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SMYD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SMYD1 gene:
Search GeneIP for patents involving SMYD1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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SMYD1 Gene

SET and MYND domain containing 1

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SET and MYND domain containing 1

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