Aliases for SMYD1 Gene
External Ids for SMYD1 Gene
GeneCards Summary for SMYD1 Gene
SMYD1 (SET And MYND Domain Containing 1) is a Protein Coding gene. Diseases associated with SMYD1 include hypoplastic left heart syndrome. Among its related pathways are Heart Development. GO annotations related to this gene include transcription corepressor activity and histone-lysine N-methyltransferase activity. An important paralog of this gene is SMYD2.
UniProtKB/Swiss-Prot for SMYD1 Gene
Methylates histone H3 at Lys-4 (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis