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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SMU1 Gene

protein-coding   GIFtS: 51
GCID: GC09M033041

Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog (C. Elegans)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Smu-1 Suppressor Of Mec-8 And Unc-52 Homolog (C. Elegans)1 2     SMU-12
Functional Spliceosome-Associated Protein 571 2     Brain-Enriched WD-Repeat Protein2
Smu-1 Suppressor Of Mec-8 And Unc-52 Protein Homolog2 3     fSAP572
BWD2     WD40 Repeat-Containing Protein SMU12
RP11-54K16.32     

External Ids:    HGNC: 182471   Entrez Gene: 552342   Ensembl: ENSG000001226927   UniProtKB: Q2TAY73   

Export aliases for SMU1 gene to outside databases

Previous GC identifers: GC09M033038 GC09M033039 GC09M033000


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SMU1 Gene: 
SMU1 (smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)) is a protein-coding gene. Diseases associated with SMU1 include lissencephaly. An important paralog of this gene is WDR83.

Gene Wiki entry for SMU1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008413.18  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SMU1 gene promoter:
         Elk-1   AML1a   XBP-1   LCR-F1   USF-1   COMP1   FOXO4   Zic1   IRF-7A   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSMU1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SMU1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMU1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p12   Ensembl cytogenetic band:  9p21.1   HGNC cytogenetic band: 9p12

SMU1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SMU1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M033041:  view genomic region     (about GC identifiers)

Start:
33,041,762 bp from pter      End:
33,076,714 bp from pter
Size:
34,953 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SMU1_HUMAN, Q2TAY7 (See protein sequence)
Recommended Name: WD40 repeat-containing protein SMU1  
Size: 513 amino acids; 57544 Da
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Secondary accessions: Q9BU59 Q9HA96 Q9NVD1

Explore the universe of human proteins at neXtProt for SMU1: NX_Q2TAY7

Explore proteomics data for SMU1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q2TAY7

  • SMU1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SMU1 Protein Expression
    REFSEQ proteins: NP_060695.2  
    ENSEMBL proteins: 
     ENSP00000380336   ENSP00000443639  

    Human Recombinant Protein Products for SMU1: 
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    Novus Biologicals SMU1 Protein
    Novus Biologicals SMU1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SMU1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    SMU1 for ontologies           About GeneDecksing



    SMU1 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for SMU1 
    Cloud-Clone Corp. CLIAs for SMU1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    WDR: WD repeat domain containing

    5/7 InterPro protein domains (see all 7):
     IPR019775 WD40_repeat_CS
     IPR006595 CTLH_C
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR017986 WD40_repeat_dom

    Graphical View of Domain Structure for InterPro Entry Q2TAY7

    ProtoNet protein and cluster: Q2TAY7

    2 Blocks protein domains:
    IPB006594 Lissencephaly type-1-like homology motif
    IPB006595 CTLH


    UniProtKB/Swiss-Prot: SMU1_HUMAN, Q2TAY7
    Similarity: Belongs to the WD repeat SMU1 family
    Similarity: Contains 1 CTLH domain
    Similarity: Contains 1 LisH domain
    Similarity: Contains 6 WD repeats


    SMU1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    SMU1 for ontologies           About GeneDecksing


    Phenotypes:
         10 GenomeRNAi human phenotypes for SMU1:
     Cell cycle / mitosis defect  Cell division defect  Decreased POU5F1-GFP protein e  Decreased cell number, increas 
     Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Decreased viability of wild-ty  Increased gamma-H2AX phosphory 
     Increased number of mitotic ce  Metaphase cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SMU1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SMU1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SMU1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SMU1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SMU1
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SMU1 (see all 24):
    hsa-miR-582-3p hsa-miR-320a hsa-miR-579 hsa-miR-607 hsa-miR-657 hsa-miR-944 hsa-miR-512-3p hsa-miR-570
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMU1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SMU1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/23 Interacting proteins for SMU1 (Q2TAY72, 3 ENSP000003803364) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GRB2P629932, 3, ENSP000003390074MINT-61564 I2D: score=2 STRING: ENSP00000339007
    IKQ131232, ENSP000003963014MINT-8331888 MINT-8337486 STRING: ENSP00000396301
    CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
    RAE1P784063, ENSP000003602864I2D: score=1 STRING: ENSP00000360286
    YBX1P678092, ENSP000003616264MINT-8335550 STRING: ENSP00000361626
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SMU1

    Search CenterWatch for drugs/clinical trials and news about SMU1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SMU1 gene: 
    NM_018225.2  

    Unigene Cluster for SMU1:

    Smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
    Hs.655351  [show with all ESTs]
    Unigene Representative Sequence: NM_018225
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397149(uc003zsf.1 uc011lnu.1) ENST00000536631
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SMU1
    8/24 QIAGEN miScript miRNA Assays for microRNAs that regulate SMU1 (see all 24):
    hsa-miR-582-3p hsa-miR-320a hsa-miR-579 hsa-miR-607 hsa-miR-657 hsa-miR-944 hsa-miR-512-3p hsa-miR-570
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
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    Clone
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    OriGene clones in human, mouse for SMU1 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: SMU1 (NM_018225)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SMU1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMU1
    Sirion Biotech Customized lentivirus for stable overexpression of SMU1 
                         Customized lentivirus expression plasmids for stable overexpression of SMU1 
    Primer
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    OriGene qPCR primer pairs and template standards for SMU1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMU1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMU1

    Additional mRNA sequence: 

    AK001667.1 AK001732.1 AK022032.1 AK225559.1 AK225587.1 AK304767.1 AL512690.1 BC002876.2 
    BC110654.1 EF011613.1 

    9 DOTS entries:

    DT.210659  DT.97791059  DT.92432544  DT.100645609  DT.95302517  DT.121172181  DT.100806369  DT.121379223 
    DT.40129659 

    24/608 AceView cDNA sequences (see all 608):

    AI302190 BU679188 CB268013 CR605922 AA358194 BE156676 H43230 CA418725 
    BI521257 AU133137 BU076050 BU609107 R92673 AK001667 AW016571 CB241604 
    CB131791 T54764 BQ421951 AW575684 BX093840 X55415 AI801488 BQ002021 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SMU1 expression in normal human tissues (normalized intensities)      SMU1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGGCCCAT
    SMU1 Expression
    About this image


    SMU1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/24 selected tissues (see all 24) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             testis ; cells in seminiferus ducts   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Metanephros
             kidney ; cells in tubules   

    See SMU1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SMU1

    SOURCE GeneReport for Unigene cluster: Hs.655351
        SABiosciences Custom PCR Arrays for SMU1
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMU1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SMU1 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Smu11 , 5 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)1, 5 91.36(n)1
    100(a)1
      4 (20.46 cM)5
    742551  NM_021535.41  NP_067510.31 
     407365425 
    chicken
    (Gallus gallus)
    Aves SMU11 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 83.95(n)
    99.61(a)
      427377  NM_001007979.1  NP_001007980.1 
    lizard
    (Anolis carolinensis)
    Reptilia SMU16
    Uncharacterized protein
    99(a)
    1 ↔ 1
    GL343257.1(110035-124101)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.77092 Xenopus laevis transcribed sequence with moderate similarity more 81.39(n)    BU910616.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561472 hypothetical protein MGC56147 80.61(n)   393168  BC045945.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG54511 CG5451 68.24(n)
    78.59(a)
      42272  NM_142509.4  NP_650766.1 
    worm
    (Caenorhabditis elegans)
    Secernentea smu-11 Protein SMU-1 59.34(n)
    62.77(a)
      173175  NM_060878.4  NP_493279.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TUP16
    General repressor of transcription, forms complex ...
    4(a)
    1 → many
    III(260311-262452)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons SMU11 WD40 repeat-containing protein SMU1 63.08(n)
    64.97(a)
      843707  NM_106031.3  NP_177513.2 
    rice
    (Oryza sativa)
    Liliopsida Os.11132 Oryza sativa (japonica cultivar-group) P0426D06.17 more 70.67(n)    AK121409.1 


    ENSEMBL Gene Tree for SMU1 (if available)
    TreeFam Gene Tree for SMU1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SMU1 gene
    WDR832  POC1B2  WDR52  WDR482  ATG16L12  SNRNP402  WDR5B2  PAFAH1B12  
    DAW12  PRPF42  WDR382  ATG16L22  POC1A2  
    8 SIMAP similar genes for SMU1 using alignment to 3 protein entries:     SMU1_HUMAN (see all proteins):
    WSB1    GNB5    WDR48    POC1B    WDR61    WDR5
    PF20    WDR5B

    SMU1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SMU1
    PGOHUM00000259500


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/800 SNPs in SMU1 are shown (see all 800)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs105964741,2
    C--33002403(+) AAAAA-/AA/AAA
            
    GCCAT
    2 -- ut311NA 2
    rs1508912981,2
    --33041443(+) TAGCCA/GGGTGT 1 -- ds50010--------
    rs78704121,2
    C,F,A,H--33041532(+) agcgaA/Gccaag 1 -- ds50018Minor allele frequency- G:0.17NA WA CSA EA 134
    rs1393616991,2
    C--33041552(+) TTGTAC/TTCCAG 1 -- ds50010--------
    rs354946621,2
    C--33041606(+) AAAAA-/A/AAA 
            
    CTCGT
    1 -- ds50011NA 2
    rs1872031171,2
    --33041631(+) TACTGC/TGCATT 1 -- ds50010--------
    rs1916259501,2
    --33041682(+) ATGGTG/TAATGT 1 -- ds50010--------
    rs1500254061,2
    --33041721(+) TACATA/GTGTAC 1 -- ds50010--------
    rs1160645731,2
    F--33041804(+) TTTGAT/CACATG 1 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1467739871,2
    C--33041836(+) AAATG-/AAAT  
            
    AAGCC
    1 -- ds50010--------

    HapMap Linkage Disequilibrium report for SMU1 (33041762 - 33076714 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for SMU1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2738370CNV Deletion23290073
    esv2347895CNV Deletion18987734
    esv1029480CNV Deletion17803354
    nsv509299CNV Insertion20534489
    nsv893017CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SMU1
    DNA2.0 Custom Variant and Variant Library Synthesis for SMU1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SMU1:    About MalaCards
    lissencephaly    


    SMU1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SMU1
    Human Genome Epidemiology (HuGE) Navigator: SMU1 (1 document)

    Export disorders for SMU1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SMU1 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with SMU1)
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    1. Analysis of smu-1, a gene that regulates the alternative splicing of unc-52 pre-mRNA in Caenorhabditis elegans. (PubMed id 11438655)1, 3, 9 Spike C.A....Herman R.K. (2001)
    2. Cloning and molecular characterization of a novel gene encoding a WD-repeat protein expressed in restricted areas of adult rat brain. (PubMed id 11410362)1, 3, 9 Di Benedetto A.J....Glavan B.J. (2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Loss of Smu1 function de-represses DNA replication and over-activates ATR-dependent replication checkpoint. (PubMed id 23727573)1 Ren L....Li M. (2013)
    8. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55234 HGNC: 18247 AceView: B4GALT1andSMU1andLOC401500 Ensembl:ENSG00000122692 euGenes: HUgn55234
    ECgene: SMU1 H-InvDB: SMU1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SMU1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SMU1 gene:
    Search GeneIP for patents involving SMU1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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