Aliases for SMS Gene
External Ids for SMS Gene
Previous HGNC Symbols for SMS Gene
Previous GeneCards Identifiers for SMS Gene
This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
GeneCards Summary for SMS Gene
SMS (Spermine Synthase) is a Protein Coding gene. Diseases associated with SMS include Mental Retardation, X-Linked, Snyder-Robinson Type and Hand Dermatosis. Among its related pathways are Urea cycle and metabolism of amino groups and Metabolism. GO annotations related to this gene include spermidine synthase activity and spermine synthase activity.
UniProtKB/Swiss-Prot for SMS Gene
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).