Aliases for SMS Gene
External Ids for SMS Gene
Previous HGNC Symbols for SMS Gene
Previous GeneCards Identifiers for SMS Gene
This gene encodes a protein belonging to the spermidine/spermin synthase family. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene are associated with X-linked Snyder-Robinson mental retardation syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
GeneCards Summary for SMS Gene
SMS (Spermine Synthase) is a Protein Coding gene. Diseases associated with SMS include Mental Retardation, X-Linked, Snyder-Robinson Type and Smith-Magenis Syndrome. Among its related pathways are beta-Alanine metabolism (KEGG) and Urea cycle and metabolism of amino groups. GO annotations related to this gene include spermidine synthase activity and spermine synthase activity.
UniProtKB/Swiss-Prot for SMS Gene
Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).