Aliases for SMPDL3A Gene
External Ids for SMPDL3A Gene
Previous GeneCards Identifiers for SMPDL3A Gene
GeneCards Summary for SMPDL3A Gene
SMPDL3A (Sphingomyelin Phosphodiesterase Acid Like 3A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include hydrolase activity and sphingomyelin phosphodiesterase activity. An important paralog of this gene is SMPDL3B.
UniProtKB/Swiss-Prot for SMPDL3A Gene
Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (PubMed:25288789, PubMed:26783088). Has in vitro activity with p-nitrophenyl-TMP (PubMed:25288789). Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (PubMed:25288789, PubMed:26783088). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine (PubMed:26783088). Does not have sphingomyelin phosphodiesterase activity (PubMed:25288789, PubMed:26783088).