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Aliases for SMPD5 Gene

Aliases for SMPD5 Gene

  • Sphingomyelin Phosphodiesterase 5 3
  • CTD-3065J16.6 3

External Ids for SMPD5 Gene

Previous GeneCards Identifiers for SMPD5 Gene

  • GC08P145105

Summaries for SMPD5 Gene

GeneCards Summary for SMPD5 Gene

SMPD5 (Sphingomyelin Phosphodiesterase 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMPD5 Gene

Genomics for SMPD5 Gene

Genomic Location for SMPD5 Gene

144,047,114 bp from pter
144,051,294 bp from pter
4,181 bases
Plus strand

Genomic View for SMPD5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SMPD5 Gene

No data available for Regulatory Elements for SMPD5 Gene

Proteins for SMPD5 Gene

Post-translational modifications for SMPD5 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMPD5 Gene

Domains & Families for SMPD5 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMPD5 Gene

Function for SMPD5 Gene

Phenotypes for SMPD5 Gene

GenomeRNAi human phenotypes for SMPD5:
genes like me logo Genes that share phenotypes with SMPD5: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMPD5 Gene

Localization for SMPD5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMPD5 Gene

Pathways & Interactions for SMPD5 Gene

SuperPathways for SMPD5 Gene

No Data Available

Interacting Proteins for SMPD5 Gene

Gene Ontology (GO) - Biological Process for SMPD5 Gene


No data available for Pathways by source and SIGNOR curated interactions for SMPD5 Gene

Drugs & Compounds for SMPD5 Gene

No Compound Related Data Available

Transcripts for SMPD5 Gene

mRNA/cDNA for SMPD5 Gene

(6) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:

Unigene Clusters for SMPD5 Gene

Sphingomyelin phosphodiesterase 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMPD5 Gene

No ASD Table

Relevant External Links for SMPD5 Gene

GeneLoc Exon Structure for

Expression for SMPD5 Gene

mRNA expression in normal human tissues for SMPD5 Gene

mRNA differential expression in normal tissues according to GTEx for SMPD5 Gene

This gene is overexpressed in Whole Blood (x8.3).

SOURCE GeneReport for Unigene cluster for SMPD5 Gene Hs.711115

genes like me logo Genes that share expression patterns with SMPD5: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SMPD5 Gene

Orthologs for SMPD5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMPD5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SMPD5 35
  • 78.11 (n)
  • 69.97 (a)
(Canis familiaris)
Mammalia LOC102156747 35
  • 74.34 (n)
  • 63.49 (a)
(Mus musculus)
Mammalia Smpd5 35
  • 72.46 (n)
  • 67.37 (a)
Smpd5 16
(Rattus norvegicus)
Mammalia Smpd5 35
  • 71.84 (n)
  • 67.89 (a)
Species with no ortholog for SMPD5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for SMPD5 Gene

Paralogs for SMPD5 Gene

No data available for Paralogs for SMPD5 Gene

Variants for SMPD5 Gene

Sequence variations from dbSNP and Humsavar for SMPD5 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs28450485 -- 144,049,772(+) GCGGC(A/G)CCTCA reference, missense
rs28483161 -- 144,048,488(+) CCACA(A/G)GGCCG intron-variant
rs73379142 -- 144,048,519(+) TTTGG(A/G)GGACT intron-variant
rs73379143 -- 144,050,453(+) CTGCT(C/G)GAAAG missense, reference, intron-variant
rs115658426 -- 144,049,713(+) CTGGC(C/G)CCCAA synonymous-codon, reference

Relevant External Links for SMPD5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SMPD5 Gene

Disorders for SMPD5 Gene

genes like me logo Genes that share disorders with SMPD5: view

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for SMPD5 Gene

Publications for SMPD5 Gene

No publications were found for SMPD5 Gene.

Products for SMPD5 Gene

Sources for SMPD5 Gene

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