SMPD4 Gene
protein-coding GIFtS: 52
GCID: GC02M130908
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sphingomyelin phosphodiesterase 4, neutral membrane (neutral...
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Aliases
for SMPD4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Sphingomyelin Phosphodiesterase 4, Neutral Membrane (NeutralSphingomyelinase-3)1 2 | | FLJ202971 | | NET131 2 | | FLJ207561 | | NSMASE31 2 | | NSMASE-32 | | KIAA14181 3 | | SKNY Protein2 | | NSMase-31 | | Sphingomyelin Phosphodiesterase 42 | | Neutral Sphingomyelinase 32 3 | | EC 3.1.4.123 | | Neutral Sphingomyelinase III2 3 | | NSMase31 |
| External Ids: | HGNC: 329491 | Entrez Gene: 556272 | Ensembl: ENSG000001366997 | OMIM: 6104575 | UniProtKB: Q9NXE43 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n409101 | |
Export aliases for SMPD4 gene to outside databasesPrevious GC identifers: GC02M130626 GC02M123204
Summaries
for SMPD4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SMPD4:
Sphingomyelinases (EC 3.1.4.12), such as SMPD4, catalyze the hydrolysis of membrane sphingomyelin to formphosphorylcholine and ceramide (Krut et al., 2006 (PubMed 16517606)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: NSMA3_HUMAN, Q9NXE4Function: Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide
Gene Wiki entry for SMPD4
|
Genomic Views
for SMPD4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022135.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SMPD4 gene promoter:
HFH-3 Sox5 Sp1 CUTL1 XBP-1 Arnt E47 FOXI1 RORalpha1 AREB6
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMPD4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMPD4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q21.1 Ensembl cytogenetic band: 2q21.1 HGNC cytogenetic band: 2q21.1SMPD4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M130908: view genomic region
(about GC identifiers)
Start:
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130,908,965 bp from pter |
End:
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130,940,323 bp from pter |
Size:
|
31,359 bases |
Orientation:
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minus strand |
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Proteins
for SMPD4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: NSMA3_HUMAN, Q9NXE4 (See
protein sequence)Recommended Name: Sphingomyelin phosphodiesterase 4 Size: 827 amino acids; 93352 Da
Cofactor: Magnesium
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane;Single-pass membrane protein
Sequence caution: Sequence=BAA91368.1; Type=Erroneous initiation; Sequence=BAA91567.1; Type=Erroneous initiation;Sequence=BAA92656.1; Type=Erroneous initiation;
Secondary accessions: B4DRB8 E7ESA2 Q6FI76 Q6P1P7 Q6ZT43 Q9H0M2 Q9NW20 Q9NWL2 Q9P2C9Alternative splicing: 6 isoforms: Q9NXE4-1 Q9NXE4-2 Q9NXE4-3 Q9NXE4-4 Q9NXE4-5 Q9NXE4-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SMPD4: NX_Q9NXE4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NXE4
SMPD4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001164554.1 NP_060221.2 NP_060421.2
ENSEMBL proteins: ENSP00000407591 ENSP00000403002 ENSP00000397278 ENSP00000259217 ENSP00000401648 ENSP00000386531 ENSP00000397078 ENSP00000403915 ENSP00000406325 ENSP00000405363 ENSP00000393791 ENSP00000416208 ENSP00000406458 ENSP00000405187 ENSP00000394313 ENSP00000339721 ENSP00000387762 ENSP00000397479 ENSP00000391896 Reactome Protein details: Q9NXE4
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
SMPD4 for ontologies About GeneDecksing
SMPD4 Antibody Products:
Assay Products for SMPD4: |
Protein
Domains /
Families
for SMPD4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SMPD4 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9NXE4ProtoNet protein and cluster: Q9NXE4 |
Function
for SMPD4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: NSMA3_HUMAN, Q9NXE4Function: Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramideCatalytic activity: Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholineEnzyme regulation: Activated by phosphatidylserine and tumor necrosis factor (TNF). Inhibited by scyphostatinBiophysicochemical properties: pH dependence: Optimum pH is 7.0;Enzyme Number (IUBMB): EC 3.1.4.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for SMPD4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMPD4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMPD4 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004767 | sphingomyelin phosphodiesterase activity |
TAS | -- | | GO:0046872 | metal ion binding |
IEA | -- | | GO:0050290 | sphingomyelin phosphodiesterase D activity |
IDA | 16517606 |
SMPD4 for ontologies About GeneDecksing
|
Pathways & Interactions
for SMPD4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | Metabolism | | | 3 | sphingomyelin metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for SMPD4
4 
Reactome Pathways for SMPD4
2 
Kegg Pathways (Kegg details for SMPD4):
SMPD4 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SMPD4
2 Interacting proteins for SMPD4 (Q9NXE43) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
SMPD4 for ontologies About GeneDecksing
|
Drugs & Compounds
for SMPD4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMPD4
10/277 HMDB Compounds for SMPD4 (see all 277) About this table
1 DrugBank Compound for SMPD4 About this table
Search CenterWatch for drugs/clinical trials and news about SMPD4 / NSMA3
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Transcripts
for SMPD4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SMPD4 gene (4 alternative transcripts): NM_001171084.1 NM_001171083.2 NM_017751.4 NM_017951.4 Unigene Cluster for SMPD4: Sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) Hs.516450 [show with all ESTs]Unigene Representative Sequence: NR_03323018/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25): ENST00000454468 ENST00000412570 ENST00000433118 ENST00000351288 ENST00000491319
ENST00000491128 ENST00000482171(uc002tqo.2) ENST00000439886(uc002tqp.2)
ENST00000409031(uc002tqq.2 uc002tqs.2 uc002tqr.2 uc010zaa.2 uc002tqt.2 uc010zac.2)
ENST00000457039 ENST00000449159 ENST00000461187 ENST00000430682 ENST00000451542
ENST00000435455 ENST00000473720 ENST00000455548 ENST00000439029
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): SMPD4 (NM_017751) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMPD4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMPD4 |
Additional cDNA sequence: AB037839.1 AF052134.1 AK000304.1 AK000763.1 AK001227.1 AK056501.1 AK297257.1 AK298609.1 AK299185.1 AK301576.1 AK303427.1 AK303519.1 AL136737.1 BC040941.1 BC064947.1 CR533550.1 EU367941.1 NR_033230.2 NR_033231.2 NR_033232.2 24/51 DOTS entries (see all 51): DT.95197752 DT.95357791 DT.100812250 DT.100687923 DT.75116930 DT.100770995 DT.91906072 DT.95357895 DT.100828532 DT.100828524 DT.95288728 DT.100040544 DT.95175789 DT.100705237 DT.100828541 DT.120981062 DT.100828526 DT.100639700 DT.100828531 DT.100828540 DT.120981411 DT.100696219 DT.120981393 DT.120981453 24/441 AceView cDNA sequences (see all 441): BQ053365 BE394493 BQ061712 BQ960112 BX402032 BX382883 BU501958 BU839704 BQ071044 BU183651 CA432590 AW470904 BI085068 AW298068 BE908461 CR614315 AI393912 BQ688894 BU148777 BQ651962 BQ944977 BX282168 BQ061738 BQ051799
GeneLoc Exon Structure
|
Expression
for SMPD4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SMPD4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCTTGCTTC
About this image
See SMPD4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SMPD4
SOURCE GeneReport for Unigene cluster: Hs.516450
UniProtKB/Swiss-Prot: NSMA3_HUMAN, Q9NXE4Tissue specificity: Widely expressed, with highest levels in heart and skeletal muscle
SABiosciences Custom PCR Arrays for SMPD4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMPD4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SMPD4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMPD4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMPD4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMPD4 |
Orthologs
for SMPD4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SMPD4 gene from 6/22 species (see all 22) About this table
ENSEMBL Gene Tree for SMPD4 (if available)
TreeFam Gene Tree for SMPD4 (if available) |
Paralogs
for SMPD4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SMPD4 gene
SMPD4 for paralogs About GeneDecksing
5/6 Pseudogenes.org Pseudogenes for SMPD4 (see all 6)
PGOHUM00000248303 PGOHUM00000248304 PGOHUM00000246243 PGOHUM00000246244 PGOHUM00000250475
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Genomic Variants
for SMPD4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SMPD4 (130908965 - 130940323 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for SMPD4
4 CNVs: 0269 3393 2408 8387 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMPD4 |
|
Disorders
/ Diseases
for SMPD4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SMPD4 for disorders About GeneDecksing
OMIM gene information: 610457
OMIM disorders: --
3  diseases for SMPD4: About MalaCardsbreast cancer immunodeficiency neuronitis
Human Genome Epidemiology (HuGE) Navigator: SMPD4 (3 documents)
Export disorders for SMPD4 gene to outside databases
|
Publications
for SMPD4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SMPD4 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with SMPD4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Novel tumor necrosis factor-responsive mammalian neutral sphingomyelinase-3 is a C-tail-anchored protein. (PubMed id 16517606)1, 2, 3, 7 Krut O.... Kroenke M. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (2000)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for SMPD4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SMPD4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SMPD4 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SMPD4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SMPD4 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SMPD4 gene:
Search GeneIP for patents involving SMPD4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SMPD4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SMPD4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMPD4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMPD4 | | | OriGene Protein Over-expression Lysate for SMPD4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SMPD4 | | OriGene 3'-UTR Clone for SMPD4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMPD4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SMPD4 | | OriGene Custom Protein Services for SMPD4 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMPD4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMPD4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMPD4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMPD4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMPD4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMPD4 |
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| | | | Search Tocris compounds for SMPD4 |
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 | | | SMPD4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMPD4 |
|  |  |  | | | | ThermoFisher Antibodies for SMPD4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMPD4 |
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