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Aliases for SMIM7 Gene

Aliases for SMIM7 Gene

  • Small Integral Membrane Protein 7 2 3 5
  • C19orf42 3 4
  • Chromosome 19 Open Reading Frame 42 2
  • UPF0608 Protein C19orf42 3

External Ids for SMIM7 Gene

Previous HGNC Symbols for SMIM7 Gene

  • C19orf42

Previous GeneCards Identifiers for SMIM7 Gene

  • GC19M016742

Summaries for SMIM7 Gene

GeneCards Summary for SMIM7 Gene

SMIM7 (Small Integral Membrane Protein 7) is a Protein Coding gene. An important paralog of this gene is ENSG00000268790.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM7 Gene

Genomics for SMIM7 Gene

Regulatory Elements for SMIM7 Gene

Enhancers for SMIM7 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SMIM7 on UCSC Golden Path with GeneCards custom track

Promoters for SMIM7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SMIM7 on UCSC Golden Path with GeneCards custom track

Genomic Location for SMIM7 Gene

Chromosome:
19
Start:
16,630,743 bp from pter
End:
16,660,442 bp from pter
Size:
29,700 bases
Orientation:
Minus strand

Genomic View for SMIM7 Gene

Genes around SMIM7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM7 Gene

Proteins for SMIM7 Gene

  • Protein details for SMIM7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ49-SMIM7_HUMAN
    Recommended name:
    Small integral membrane protein 7
    Protein Accession:
    Q9BQ49
    Secondary Accessions:
    • A8MX44

    Protein attributes for SMIM7 Gene

    Size:
    75 amino acids
    Molecular mass:
    8631 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM7 Gene

Proteomics data for SMIM7 Gene at MOPED

Post-translational modifications for SMIM7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SMIM7 Gene

Domains & Families for SMIM7 Gene

Protein Domains for SMIM7 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SMIM7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BQ49

UniProtKB/Swiss-Prot:

SMIM7_HUMAN :
  • Belongs to the SMIM7 family.
Family:
  • Belongs to the SMIM7 family.
genes like me logo Genes that share domains with SMIM7: view

No data available for Gene Families for SMIM7 Gene

Function for SMIM7 Gene

genes like me logo Genes that share phenotypes with SMIM7: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMIM7 Gene

Localization for SMIM7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM7 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SMIM7 Gene COMPARTMENTS Subcellular localization image for SMIM7 gene
Compartment Confidence
extracellular 2
golgi apparatus 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for SMIM7 Gene

Pathways & Interactions for SMIM7 Gene

SuperPathways for SMIM7 Gene

No Data Available

Interacting Proteins for SMIM7 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000417147%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000417147 for SMIM7 Gene via STRING

Gene Ontology (GO) - Biological Process for SMIM7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM7 Gene

Drugs & Compounds for SMIM7 Gene

No Compound Related Data Available

Transcripts for SMIM7 Gene

Unigene Clusters for SMIM7 Gene

Small integral membrane protein 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM7 Gene

No ASD Table

Relevant External Links for SMIM7 Gene

GeneLoc Exon Structure for
SMIM7
ECgene alternative splicing isoforms for
SMIM7

Expression for SMIM7 Gene

mRNA expression in normal human tissues for SMIM7 Gene

Protein differential expression in normal tissues from HIPED for SMIM7 Gene

This gene is overexpressed in Nasal epithelium (58.6) and Bone (8.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SMIM7 Gene



SOURCE GeneReport for Unigene cluster for SMIM7 Gene Hs.356467

genes like me logo Genes that share expression patterns with SMIM7: view

Protein tissue co-expression partners for SMIM7 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SMIM7 Gene

Orthologs for SMIM7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM7 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SMIM7 35
  • 93.78 (n)
  • 98.67 (a)
-- 36
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SMIM7 35
  • 93.78 (n)
  • 98.67 (a)
C19ORF42 36
  • 96 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Smim7 35
  • 85.78 (n)
  • 96 (a)
Smim7 16
Smim7 36
  • 96 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf42 35
  • 99.11 (n)
  • 100 (a)
-- 36
  • 70 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Smim7 35
  • 86.67 (n)
  • 97.33 (a)
chicken
(Gallus gallus)
Aves C28H19ORF42 35
  • 79.56 (n)
  • 82.67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia smim7 35
  • 76.89 (n)
  • 86.67 (a)
zebrafish
(Danio rerio)
Actinopterygii smim7 35
  • 74.22 (n)
  • 86.67 (a)
smim7 36
  • 84 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 72 (a)
OneToMany
Species with no ortholog for SMIM7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM7 Gene

ENSEMBL:
Gene Tree for SMIM7 (if available)
TreeFam:
Gene Tree for SMIM7 (if available)

Paralogs for SMIM7 Gene

Paralogs for SMIM7 Gene

Pseudogenes.org Pseudogenes for SMIM7 Gene

genes like me logo Genes that share paralogs with SMIM7: view

Variants for SMIM7 Gene

Sequence variations from dbSNP and Humsavar for SMIM7 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7351094 -- 16,630,737(+) CACAA(A/C)ACACA downstream-variant-500B
rs8101030 -- 16,650,266(+) TCCAT(A/C/G)TATCT intron-variant
rs8102804 -- 16,653,870(+) agttt(A/G)ggcga intron-variant
rs8103249 -- 16,647,328(+) GTCAG(C/T)GATTA intron-variant
rs12985699 -- 16,642,421(+) ggcag(A/G)cacct intron-variant

Variation tolerance for SMIM7 Gene

Residual Variation Intolerance Score: 54.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.22; 4.84% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SMIM7 Gene

Disorders for SMIM7 Gene

Relevant External Links for SMIM7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMIM7

No disorders were found for SMIM7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM7 Gene

Publications for SMIM7 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for SMIM7 Gene

Sources for SMIM7 Gene

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