Free for academic non-profit institutions. Other users need a Commercial license

Aliases for SMIM7 Gene

Aliases for SMIM7 Gene

  • Small Integral Membrane Protein 7 2 3
  • C19orf42 3 4
  • Chromosome 19 Open Reading Frame 42 2
  • UPF0608 Protein C19orf42 3

External Ids for SMIM7 Gene

Previous HGNC Symbols for SMIM7 Gene

  • C19orf42

Previous GeneCards Identifiers for SMIM7 Gene

  • GC19M016742

Summaries for SMIM7 Gene

GeneCards Summary for SMIM7 Gene

SMIM7 (Small Integral Membrane Protein 7) is a Protein Coding gene. An important paralog of this gene is ENSG00000268790.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM7 Gene

Genomics for SMIM7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SMIM7 Gene

16,630,751 bp from pter
16,660,442 bp from pter
29,692 bases
Minus strand

Genomic View for SMIM7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMIM7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM7 Gene

No data available for Regulatory Elements for SMIM7 Gene

Proteins for SMIM7 Gene

  • Protein details for SMIM7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Small integral membrane protein 7
    Protein Accession:
    Secondary Accessions:
    • A8MX44

    Protein attributes for SMIM7 Gene

    75 amino acids
    Molecular mass:
    8631 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM7 Gene

Proteomics data for SMIM7 Gene at MOPED

Post-translational modifications for SMIM7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SMIM7 Gene

Domains for SMIM7 Gene

Protein Domains for SMIM7 Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9BQ49
  • Belongs to the SMIM7 family.
genes like me logo Genes that share domains with SMIM7: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SMIM7 Gene

Function for SMIM7 Gene

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SMIM7 Gene

Localization for SMIM7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM7 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM7: view

No data available for Subcellular locations from COMPARTMENTS for SMIM7 Gene

Pathways for SMIM7 Gene

SuperPathways for SMIM7 Gene

No Data Available

Interacting Proteins for SMIM7 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000417147 for SMIM7 Gene via STRING

Gene Ontology (GO) - Biological Process for SMIM7 Gene


No data available for Pathways by source for SMIM7 Gene

Transcripts for SMIM7 Gene

Unigene Clusters for SMIM7 Gene

Small integral membrane protein 7:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM7

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM7 Gene

No ASD Table

Relevant External Links for SMIM7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SMIM7 Gene

mRNA expression in normal human tissues for SMIM7 Gene

Protein differential expression in normal tissues for SMIM7 Gene

This gene is overexpressed in Nasal epithelium (58.6) and Bone (8.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SMIM7 Gene

SOURCE GeneReport for Unigene cluster for SMIM7 Gene Hs.356467

genes like me logo Genes that share expressions with SMIM7: view

Expression partners for SMIM7 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SMIM7 Gene

Orthologs for SMIM7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SMIM7 35
  • 93.78 (n)
  • 98.67 (a)
-- 36
  • 95 (a)
(Canis familiaris)
Mammalia SMIM7 35
  • 93.78 (n)
  • 98.67 (a)
C19ORF42 36
  • 96 (a)
(Mus musculus)
Mammalia Smim7 35
  • 85.78 (n)
  • 96 (a)
Smim7 16
Smim7 36
  • 96 (a)
(Pan troglodytes)
Mammalia C19H19orf42 35
  • 99.11 (n)
  • 100 (a)
-- 36
  • 70 (a)
(Rattus norvegicus)
Mammalia Smim7 35
  • 86.67 (n)
  • 97.33 (a)
(Gallus gallus)
Aves C28H19ORF42 35
  • 79.56 (n)
  • 82.67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia smim7 35
  • 76.89 (n)
  • 86.67 (a)
(Danio rerio)
Actinopterygii smim7 35
  • 74.22 (n)
  • 86.67 (a)
smim7 36
  • 84 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 72 (a)
Species with no ortholog for SMIM7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM7 Gene

Gene Tree for SMIM7 (if available)
Gene Tree for SMIM7 (if available)

Paralogs for SMIM7 Gene

Paralogs for SMIM7 Gene Pseudogenes for SMIM7 Gene

genes like me logo Genes that share paralogs with SMIM7: view

Variants for SMIM7 Gene

Sequence variations from dbSNP and Humsavar for SMIM7 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs8863 -- 16,646,454(+) GGTTT(C/T)TCAAC utr-variant-3-prime, nc-transcript-variant, intron-variant
rs10402 -- 16,646,897(+) ACGGC(C/T)GTGTT utr-variant-3-prime, intron-variant
rs706762 -- 16,647,098(+) CACCT(C/T)GGCGA utr-variant-3-prime, nc-transcript-variant, intron-variant
rs2279448 -- 16,646,735(+) TCTGT(C/T)ACAGG utr-variant-3-prime, nc-transcript-variant, intron-variant
rs3745330 -- 16,652,998(+) ACAAT(A/G)AAGTC intron-variant

Relevant External Links for SMIM7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM7 Gene

Disorders for SMIM7 Gene

No disorders were found for SMIM7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SMIM7 Gene

Publications for SMIM7 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for SMIM7 Gene

Sources for SMIM7 Gene

Back to Top