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Aliases for SMIM5 Gene

Aliases for SMIM5 Gene

  • Small Integral Membrane Protein 5 2 3 5
  • C17orf109 3 4
  • Chromosome 17 Open Reading Frame 109 2
  • PP12104 3

External Ids for SMIM5 Gene

Previous HGNC Symbols for SMIM5 Gene

  • C17orf109

Previous GeneCards Identifiers for SMIM5 Gene

  • GC17P073632

Summaries for SMIM5 Gene

GeneCards Summary for SMIM5 Gene

SMIM5 (Small Integral Membrane Protein 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM5 Gene

Genomics for SMIM5 Gene

Genomic Location for SMIM5 Gene

Chromosome:
17
Start:
75,633,434 bp from pter
End:
75,641,406 bp from pter
Size:
7,973 bases
Orientation:
Plus strand

Genomic View for SMIM5 Gene

Genes around SMIM5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM5 Gene

No data available for Regulatory Elements for SMIM5 Gene

Proteins for SMIM5 Gene

  • Protein details for SMIM5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q71RC9-SMIM5_HUMAN
    Recommended name:
    Small integral membrane protein 5
    Protein Accession:
    Q71RC9

    Protein attributes for SMIM5 Gene

    Size:
    77 amino acids
    Molecular mass:
    8540 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ15244.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=EAW89296.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for SMIM5 Gene

Proteomics data for SMIM5 Gene at MOPED

Post-translational modifications for SMIM5 Gene

No Post-translational modifications

Other Protein References for SMIM5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM5 Gene

Domains & Families for SMIM5 Gene

Protein Domains for SMIM5 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM5 Gene

Function for SMIM5 Gene

Phenotypes for SMIM5 Gene

GenomeRNAi human phenotypes for SMIM5:
genes like me logo Genes that share phenotypes with SMIM5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM5 Gene

Localization for SMIM5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM5 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SMIM5 Gene COMPARTMENTS Subcellular localization image for SMIM5 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for SMIM5 Gene

Pathways & Interactions for SMIM5 Gene

SuperPathways for SMIM5 Gene

No Data Available

Interacting Proteins for SMIM5 Gene

Gene Ontology (GO) - Biological Process for SMIM5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM5 Gene

Drugs & Compounds for SMIM5 Gene

No Compound Related Data Available

Transcripts for SMIM5 Gene

mRNA/cDNA for SMIM5 Gene

(5) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMIM5 Gene

Small integral membrane protein 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM5 Gene

No ASD Table

Relevant External Links for SMIM5 Gene

GeneLoc Exon Structure for
SMIM5
ECgene alternative splicing isoforms for
SMIM5

Expression for SMIM5 Gene

mRNA expression in normal human tissues for SMIM5 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SMIM5 Gene

This gene is overexpressed in Esophagus - Mucosa (x4.8).

Protein differential expression in normal tissues from HIPED for SMIM5 Gene

This gene is overexpressed in Platelet (27.8), Urine (20.5), and Bone (18.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SMIM5 Gene



SOURCE GeneReport for Unigene cluster for SMIM5 Gene Hs.528605

genes like me logo Genes that share expression patterns with SMIM5: view

Protein tissue co-expression partners for SMIM5 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SMIM5 Gene

Orthologs for SMIM5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SMIM5 35
  • 78.79 (n)
  • 68.83 (a)
SMIM5 36
  • 65 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SMIM5 35
  • 87.67 (n)
  • 89.04 (a)
mouse
(Mus musculus)
Mammalia Smim5 35
  • 80.95 (n)
  • 77.92 (a)
Smim5 16
Smim5 36
  • 77 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf109 35
  • 99.13 (n)
  • 98.7 (a)
SMIM5 36
  • 99 (a)
OneToOne
chicken
(Gallus gallus)
Aves SMIM5 36
  • 55 (a)
OneToOne
Species with no ortholog for SMIM5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM5 Gene

ENSEMBL:
Gene Tree for SMIM5 (if available)
TreeFam:
Gene Tree for SMIM5 (if available)

Paralogs for SMIM5 Gene

No data available for Paralogs for SMIM5 Gene

Variants for SMIM5 Gene

Variation tolerance for SMIM5 Gene

Gene Damage Index Score: 1.01; 20.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMIM5 Gene

HapMap Linkage Disequilibrium report
SMIM5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for SMIM5 Gene

Disorders for SMIM5 Gene

Relevant External Links for SMIM5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMIM5

No disorders were found for SMIM5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM5 Gene

Publications for SMIM5 Gene

  1. FUT11 as a potential biomarker of clear cell renal cell carcinoma progression based on meta-analysis of gene expression data. (PMID: 24318988) Zodro E. … Wesoly J. (Tumour Biol. 2013) 2 3 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G. … Peterson K. (Mol. Vis. 2002) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SMIM5 Gene

Sources for SMIM5 Gene

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