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Aliases for SMIM3 Gene

Aliases for SMIM3 Gene

  • Small Integral Membrane Protein 3 2 3 5
  • NGF-Induced Differentiation Clone 67 Protein 3 4
  • Small Membrane Protein NID67 3 4
  • C5orf62 3 4
  • NID67 3 4
  • Chromosome 5 Open Reading Frame 62 2
  • MST150 3

External Ids for SMIM3 Gene

Previous HGNC Symbols for SMIM3 Gene

  • C5orf62

Previous GeneCards Identifiers for SMIM3 Gene

  • GC05P150159

Summaries for SMIM3 Gene

GeneCards Summary for SMIM3 Gene

SMIM3 (Small Integral Membrane Protein 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM3 Gene

Genomics for SMIM3 Gene

Regulatory Elements for SMIM3 Gene

Enhancers for SMIM3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SMIM3 on UCSC Golden Path with GeneCards custom track

Promoters for SMIM3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SMIM3 on UCSC Golden Path with GeneCards custom track

Genomic Location for SMIM3 Gene

150,777,946 bp from pter
150,796,736 bp from pter
18,791 bases
Plus strand

Genomic View for SMIM3 Gene

Genes around SMIM3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM3 Gene

Proteins for SMIM3 Gene

  • Protein details for SMIM3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Small integral membrane protein 3
    Protein Accession:
    Secondary Accessions:
    • Q3MIG3
    • Q6ZUV4

    Protein attributes for SMIM3 Gene

    60 amino acids
    Molecular mass:
    6593 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI01839.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=AAI01841.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=AAI06041.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC86114.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=EAW61705.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for SMIM3 Gene

Proteomics data for SMIM3 Gene at MOPED

Post-translational modifications for SMIM3 Gene

No Post-translational modifications

Other Protein References for SMIM3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM3 Gene

Domains & Families for SMIM3 Gene

Protein Domains for SMIM3 Gene


Suggested Antigen Peptide Sequences for SMIM3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM3: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SMIM3 Gene

Function for SMIM3 Gene

Molecular function for SMIM3 Gene

UniProtKB/Swiss-Prot Induction:

Phenotypes for SMIM3 Gene

genes like me logo Genes that share phenotypes with SMIM3: view

Animal Models for SMIM3 Gene

MGI Knock Outs for SMIM3:

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM3 Gene

Localization for SMIM3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM3 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMIM3 Gene

Pathways & Interactions for SMIM3 Gene

SuperPathways for SMIM3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for SMIM3 Gene


No data available for Pathways by source and SIGNOR curated interactions for SMIM3 Gene

Drugs & Compounds for SMIM3 Gene

No Compound Related Data Available

Transcripts for SMIM3 Gene

mRNA/cDNA for SMIM3 Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(186) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMIM3 Gene

Small integral membrane protein 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM3 Gene

No ASD Table

Relevant External Links for SMIM3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SMIM3 Gene

mRNA expression in normal human tissues for SMIM3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SMIM3 Gene Hs.29444

genes like me logo Genes that share expression patterns with SMIM3: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SMIM3 Gene

Orthologs for SMIM3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMIM3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MGC128424 35
  • 87.22 (n)
  • 91.67 (a)
MGC128424 36
  • 92 (a)
(Canis familiaris)
Mammalia SMIM3 35
  • 90 (n)
  • 93.33 (a)
SMIM3 36
  • 93 (a)
(Mus musculus)
Mammalia Smim3 35
  • 84.75 (n)
  • 83.05 (a)
Smim3 16
Smim3 36
  • 82 (a)
(Pan troglodytes)
Mammalia SMIM3 35
  • 99.44 (n)
  • 100 (a)
SMIM3 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Smim3 35
  • 83.33 (n)
  • 83.33 (a)
(Monodelphis domestica)
Mammalia SMIM3 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia SMIM3 36
  • 68 (a)
Species with no ortholog for SMIM3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM3 Gene

Gene Tree for SMIM3 (if available)
Gene Tree for SMIM3 (if available)

Paralogs for SMIM3 Gene

No data available for Paralogs for SMIM3 Gene

Variants for SMIM3 Gene

Sequence variations from dbSNP and Humsavar for SMIM3 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1144651 -- 150,787,588(+) CTGAG(A/G/T)ATGAA intron-variant
rs1150151 -- 150,796,972(+) ACAAA(C/T)aagac downstream-variant-500B
rs1299628 -- 150,783,931(-) aaaaa(A/G)aaaaa intron-variant
rs1363569 -- 150,784,681(+) ctttt(C/T)aaccc intron-variant
rs1363570 -- 150,784,803(+) TCTCT(A/G)TGCTT intron-variant

Variation tolerance for SMIM3 Gene

Residual Variation Intolerance Score: 74.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.01; 50.00% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SMIM3 Gene

Disorders for SMIM3 Gene

Relevant External Links for SMIM3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SMIM3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM3 Gene

Publications for SMIM3 Gene

  1. NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells. (PMID: 11288140) Vician L. … Herschman H.R. (J. Neurosci. Res. 2001) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SMIM3 Gene

Sources for SMIM3 Gene