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Aliases for SMIM29 Gene

Aliases for SMIM29 Gene

  • Small Integral Membrane Protein 29 2 3
  • C6orf1 3 4 5
  • Chromosome 6 Open Reading Frame 1 2 5
  • LBH 3 4
  • Uncharacterized Protein C6orf1 3
  • Protein LBH 4

External Ids for SMIM29 Gene

Previous HGNC Symbols for SMIM29 Gene

  • C6orf1

Summaries for SMIM29 Gene

GeneCards Summary for SMIM29 Gene

SMIM29 (Small Integral Membrane Protein 29) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM29 Gene

Genomics for SMIM29 Gene

Regulatory Elements for SMIM29 Gene

Enhancers for SMIM29 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06G033428 1.6 FANTOM5 ENCODE dbSUPER 11.6 +820.4 820360 1.7 HDGF PKNOX1 ATF1 FOXA2 ZFP64 ARID4B SIN3A YBX1 DMAP1 TCF12 ZBTB9 SMIM29 RPL35AP4 KIFC1 CUTA BAK1 SYNGAP1 MIR5004
GH06G034670 1.6 Ensembl ENCODE dbSUPER 11.6 -423.8 -423838 6.3 HDGF FOXA2 PKNOX1 MLX CREB3L1 ARNT ZFP64 WRNIP1 ARID4B FEZF1 UHRF1BP1 SMIM29 GC06M037428 RN7SL200P GC06P041046
GH06G033270 1.5 ENCODE dbSUPER 11.6 +974.3 974342 8.4 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC RPS18 DAXX WDR46 BRD2 VPS52 RGL2 LEMD2 RXRB ITPR3 RING1
GH06G033430 1.5 FANTOM5 ENCODE dbSUPER 11.6 +817.1 817051 4.5 HDGF ATF1 FOXA2 ARID4B SIN3A ZNF48 GLIS2 ELK1 ZNF143 FOS RING1 HCG25 DAXX ZBTB9 SYNGAP1 LEMD2 VPS52 SMIM29 PHF1 KIFC1
GH06G034233 1.7 Ensembl ENCODE dbSUPER 6.9 +7.2 7214 17.1 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC WDR46 RPS10 DAXX LEMD2 VPS52 RGL2 HCG25 ITPR3 SYNGAP1 ZBTB22
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SMIM29 on UCSC Golden Path with GeneCards custom track

Promoters for SMIM29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195914 270 1201 HDGF HNRNPUL1 PKNOX1 MLX ARNT AGO1 ZFP64 ARID4B SIN3A DMAP1

Genomic Location for SMIM29 Gene

Chromosome:
6
Start:
34,246,380 bp from pter
End:
34,249,470 bp from pter
Size:
3,091 bases
Orientation:
Minus strand

Genomic View for SMIM29 Gene

Genes around SMIM29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM29 Gene

Proteins for SMIM29 Gene

  • Protein details for SMIM29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86T20-CF001_HUMAN
    Recommended name:
    Uncharacterized protein C6orf1
    Protein Accession:
    Q86T20
    Secondary Accessions:
    • A8K299

    Protein attributes for SMIM29 Gene

    Size:
    159 amino acids
    Molecular mass:
    17113 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM29 Gene

Post-translational modifications for SMIM29 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMIM29 Gene

Domains & Families for SMIM29 Gene

Protein Domains for SMIM29 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SMIM29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM29: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SMIM29 Gene

Function for SMIM29 Gene

genes like me logo Genes that share phenotypes with SMIM29: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM29 Gene

Localization for SMIM29 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM29 Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMIM29 gene
Compartment Confidence
extracellular 4
mitochondrion 2
plasma membrane 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for SMIM29 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM29: view

Pathways & Interactions for SMIM29 Gene

SuperPathways for SMIM29 Gene

No Data Available

Interacting Proteins for SMIM29 Gene

Selected Interacting proteins: Q86T20-CF001_HUMAN for SMIM29 Gene via IID

Symbol External ID(s) Details
HMGA1

Gene Ontology (GO) - Biological Process for SMIM29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM29 Gene

Drugs & Compounds for SMIM29 Gene

No Compound Related Data Available

Transcripts for SMIM29 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM29 Gene

No ASD Table

Relevant External Links for SMIM29 Gene

GeneLoc Exon Structure for
SMIM29
ECgene alternative splicing isoforms for
SMIM29

Expression for SMIM29 Gene

NURSA nuclear receptor signaling pathways regulating expression of SMIM29 Gene:

SMIM29

mRNA Expression by UniProt/SwissProt for SMIM29 Gene:

Q86T20-CF001_HUMAN
Tissue specificity: Expressed in spleen, thymus, prostate, testis, uterus, small intestine, colon and peripheral blood leukocytes.

Evidence on tissue expression from TISSUES for SMIM29 Gene

  • Nervous system(4.3)

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMIM29 Gene

Orthologs for SMIM29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C6H6orf1 34
  • 99.78 (n)
C6orf1 35
  • 99 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii Dr.3972 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7226 34
Species where no ortholog for SMIM29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM29 Gene

ENSEMBL:
Gene Tree for SMIM29 (if available)
TreeFam:
Gene Tree for SMIM29 (if available)

Paralogs for SMIM29 Gene

No data available for Paralogs for SMIM29 Gene

Variants for SMIM29 Gene

Sequence variations from dbSNP and Humsavar for SMIM29 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000396258 -- 34,246,423(+) AAAAT(A/G)TATAC downstream-variant-500B, utr-variant-3-prime
rs1001219180 -- 34,249,371(+) CACCC(C/G)TCTCG upstream-variant-2KB
rs1001314162 -- 34,249,913(+) ACTTT(C/T)TTTTC upstream-variant-2KB
rs1002157975 -- 34,246,927(+) CAGCA(C/T)CCAGT intron-variant
rs1003898503 -- 34,249,875(+) GGATT(A/G)GAGGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SMIM29 Gene

Variant ID Type Subtype PubMed ID
nsv602863 CNV loss 21841781
nsv602865 CNV loss 21841781
nsv969388 CNV duplication 23825009

Variation tolerance for SMIM29 Gene

Residual Variation Intolerance Score: 71.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.18; 39.51% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMIM29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMIM29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMIM29 Gene

Disorders for SMIM29 Gene

Relevant External Links for SMIM29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMIM29

No disorders were found for SMIM29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM29 Gene

Publications for SMIM29 Gene

  1. Assignment of a new gene (LBH). (PMID: 10036196) Kazmierczak B. … Bullerdiek J. (Genomics 1999) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects. (PMID: 24324551) Deng X. … Seielstad M. (PLoS ONE 2013) 3 64
  4. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. (PMID: 21998595) N'Diaye A. … Haiman C.A. (PLoS Genet. 2011) 3 64
  5. Identification of 15 loci influencing height in a Korean population. (PMID: 19893584) Kim J.J. … Lee J.K. (J. Hum. Genet. 2010) 3 64

Products for SMIM29 Gene

Sources for SMIM29 Gene

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