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Aliases for SMIM24 Gene

Aliases for SMIM24 Gene

  • Small Integral Membrane Protein 24 2 3
  • C19orf77 3 4
  • Chromosome 19 Open Reading Frame 77 2
  • Transmembrane Protein C19orf77 3
  • Transmembrane Protein HSPC323 3
  • HSPC323 3

External Ids for SMIM24 Gene

Previous HGNC Symbols for SMIM24 Gene

  • C19orf77

Summaries for SMIM24 Gene

GeneCards Summary for SMIM24 Gene

SMIM24 (Small Integral Membrane Protein 24) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM24 Gene

Genomics for SMIM24 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SMIM24 Gene

Start:
3,473,986 bp from pter
End:
3,480,542 bp from pter
Size:
6,557 bases
Orientation:
Minus strand

Genomic View for SMIM24 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMIM24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM24 Gene

No data available for Regulatory Elements for SMIM24 Gene

Proteins for SMIM24 Gene

  • Protein details for SMIM24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O75264-SIM24_HUMAN
    Recommended name:
    Small integral membrane protein 24
    Protein Accession:
    O75264
    Secondary Accessions:
    • B9EJF4
    • Q9P059

    Protein attributes for SMIM24 Gene

    Size:
    130 amino acids
    Molecular mass:
    14964 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC33194.1; Type=Erroneous gene model prediction; Note=Wrong choice of frame and superfluous exons were predicted.; Evidence={ECO:0000305}; Sequence=AAF29001.1; Type=Frameshift; Positions=111; Evidence={ECO:0000305}; Sequence=EAW69320.1; Type=Erroneous gene model prediction; Note=Wrong choice of frame and superfluous exons were predicted.; Evidence={ECO:0000305};

neXtProt entry for SMIM24 Gene

Proteomics data for SMIM24 Gene at MOPED

Post-translational modifications for SMIM24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SMIM24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM24 Gene

Domains for SMIM24 Gene

Protein Domains for SMIM24 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM24: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM24 Gene

Function for SMIM24 Gene

Gene Ontology (GO) - Molecular Function for SMIM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with SMIM24: view

Phenotypes for SMIM24 Gene

genes like me logo Genes that share phenotypes with SMIM24: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM24

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SMIM24 Gene

Localization for SMIM24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM24 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with SMIM24: view

No data available for Subcellular locations from COMPARTMENTS for SMIM24 Gene

Pathways for SMIM24 Gene

SuperPathways for SMIM24 Gene

No Data Available

Interacting Proteins for SMIM24 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000215531%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000215531 for SMIM24 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for SMIM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SMIM24: view

No data available for Pathways by source for SMIM24 Gene

Transcripts for SMIM24 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM24

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SMIM24
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM24 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b
SP1: - -
SP2:
SP3: -

Relevant External Links for SMIM24 Gene

GeneLoc Exon Structure for
SMIM24
ECgene alternative splicing isoforms for
SMIM24

Expression for SMIM24 Gene

mRNA expression in normal human tissues for SMIM24 Gene

mRNA differential expression in normal tissues according to GTEx for SMIM24 Gene

This gene is overexpressed in Kidney - Cortex (19.9), Small Intestine - Terminal Ileum (16.1), and Stomach (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SMIM24 Gene

genes like me logo Genes that share expressions with SMIM24: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for SMIM24 Gene

Orthologs for SMIM24 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMIM24 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C19orf77 36
  • 58 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C19orf77 36
  • 60 (a)
OneToOne
C20H19orf77 35
  • 76.78 (n)
  • 69.66 (a)
mouse
(Mus musculus)
Mammalia 2210404O07Rik 35
  • 70 (n)
  • 60 (a)
2210404O07Rik 16
2210404O07Rik 36
  • 60 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100366121 35
  • 69.49 (n)
  • 61.02 (a)
Species with no ortholog for SMIM24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM24 Gene

ENSEMBL:
Gene Tree for SMIM24 (if available)
TreeFam:
Gene Tree for SMIM24 (if available)

Paralogs for SMIM24 Gene

No data available for Paralogs for SMIM24 Gene

Variants for SMIM24 Gene

Sequence variations from dbSNP and Humsavar for SMIM24 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1055392 -- 3,474,473(-) TCCCA(C/T)GCACC utr-variant-3-prime
rs1860192 -- 3,481,580(+) CCCCG(C/T)GAAAT upstream-variant-2KB
rs1860193 -- 3,481,652(+) GAAGC(C/T)GGGTC upstream-variant-2KB
rs2074961 -- 3,480,360(+) TCCCC(C/T)ATCCC intron-variant
rs2240666 -- 3,480,234(+) GCGAG(A/G)GGGAG intron-variant

Relevant External Links for SMIM24 Gene

HapMap Linkage Disequilibrium report
SMIM24

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM24 Gene

Disorders for SMIM24 Gene

No disorders were found for SMIM24 Gene.

No data available for UniProtKB/Swiss-Prot for SMIM24 Gene

Publications for SMIM24 Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  5. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3

Products for SMIM24 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SMIM24
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM24
    • Block miRNA regulation of SMIM24 using miScript Target Protectors

    Sources for SMIM24 Gene

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