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Aliases for SMIM24 Gene

Aliases for SMIM24 Gene

  • Small Integral Membrane Protein 24 2 3 5
  • C19orf77 3 4
  • Chromosome 19 Open Reading Frame 77 2
  • Transmembrane Protein C19orf77 3
  • Transmembrane Protein HSPC323 3
  • HSPC323 3

External Ids for SMIM24 Gene

Previous HGNC Symbols for SMIM24 Gene

  • C19orf77

Summaries for SMIM24 Gene

GeneCards Summary for SMIM24 Gene

SMIM24 (Small Integral Membrane Protein 24) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM24 Gene

Genomics for SMIM24 Gene

Regulatory Elements for SMIM24 Gene

Promoters for SMIM24 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SMIM24 on UCSC Golden Path with GeneCards custom track

Genomic Location for SMIM24 Gene

3,473,986 bp from pter
3,480,542 bp from pter
6,557 bases
Minus strand

Genomic View for SMIM24 Gene

Genes around SMIM24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM24 Gene

Proteins for SMIM24 Gene

  • Protein details for SMIM24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Small integral membrane protein 24
    Protein Accession:
    Secondary Accessions:
    • B9EJF4
    • Q9P059

    Protein attributes for SMIM24 Gene

    130 amino acids
    Molecular mass:
    14964 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC33194.1; Type=Erroneous gene model prediction; Note=Wrong choice of frame and superfluous exons were predicted.; Evidence={ECO:0000305}; Sequence=AAF29001.1; Type=Frameshift; Positions=111; Evidence={ECO:0000305}; Sequence=EAW69320.1; Type=Erroneous gene model prediction; Note=Wrong choice of frame and superfluous exons were predicted.; Evidence={ECO:0000305};

neXtProt entry for SMIM24 Gene

Proteomics data for SMIM24 Gene at MOPED

Post-translational modifications for SMIM24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SMIM24 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM24 Gene

Domains & Families for SMIM24 Gene

Protein Domains for SMIM24 Gene


Suggested Antigen Peptide Sequences for SMIM24 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM24: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SMIM24 Gene

Function for SMIM24 Gene

genes like me logo Genes that share phenotypes with SMIM24: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMIM24 Gene

Localization for SMIM24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM24 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMIM24 Gene

Pathways & Interactions for SMIM24 Gene

SuperPathways for SMIM24 Gene

No Data Available

Interacting Proteins for SMIM24 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000215531 for SMIM24 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for SMIM24 Gene


No data available for Pathways by source and SIGNOR curated interactions for SMIM24 Gene

Drugs & Compounds for SMIM24 Gene

No Compound Related Data Available

Transcripts for SMIM24 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM24 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b
SP1: - -
SP3: -

Relevant External Links for SMIM24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SMIM24 Gene

mRNA expression in normal human tissues for SMIM24 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SMIM24 Gene

This gene is overexpressed in Kidney - Cortex (x19.9), Small Intestine - Terminal Ileum (x16.1), and Stomach (x6.1).

Protein differential expression in normal tissues from HIPED for SMIM24 Gene

This gene is overexpressed in Urine (28.8), Fetal gut (19.1), Kidney (9.9), and Adrenal (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SMIM24 Gene

genes like me logo Genes that share expression patterns with SMIM24: view

Protein tissue co-expression partners for SMIM24 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for SMIM24 Gene

Orthologs for SMIM24 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMIM24 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia C20H19orf77 35
  • 76.78 (n)
  • 69.66 (a)
C19orf77 36
  • 60 (a)
(Mus musculus)
Mammalia 2210404O07Rik 35
  • 70 (n)
  • 60 (a)
Smim24 16
2210404O07Rik 36
  • 60 (a)
(Rattus norvegicus)
Mammalia LOC100366121 35
  • 69.49 (n)
  • 61.02 (a)
(Bos Taurus)
Mammalia C19orf77 36
  • 58 (a)
Species with no ortholog for SMIM24:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM24 Gene

Gene Tree for SMIM24 (if available)
Gene Tree for SMIM24 (if available)

Paralogs for SMIM24 Gene

No data available for Paralogs for SMIM24 Gene

Variants for SMIM24 Gene

Sequence variations from dbSNP and Humsavar for SMIM24 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1055392 -- 3,474,473(-) TCCCA(C/T)GCACC utr-variant-3-prime
rs6146446 -- 3,474,238(+) GCTCA(-/AAGTCCAGGGCTCA)GGACA downstream-variant-500B
rs10413312 -- 3,478,648(+) GGAGA(C/G)GGGCG intron-variant
rs11267575 -- 3,474,215(+) GCGCT(-/CAGGGCTCAAAGTC)CAGGG downstream-variant-500B
rs10415247 -- 3,475,452(+) GGGTG(A/G)GTGGA intron-variant

Variation tolerance for SMIM24 Gene

Gene Damage Index Score: 2.14; 38.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMIM24 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM24 Gene

Disorders for SMIM24 Gene

Relevant External Links for SMIM24

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for SMIM24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM24 Gene

Publications for SMIM24 Gene

  1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3 67
  2. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for SMIM24 Gene

Sources for SMIM24 Gene

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