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Aliases for SMIM22 Gene

Aliases for SMIM22 Gene

  • Small Integral Membrane Protein 22 2 3

External Ids for SMIM22 Gene

Previous GeneCards Identifiers for SMIM22 Gene

  • GC16P004839

Summaries for SMIM22 Gene

GeneCards Summary for SMIM22 Gene

SMIM22 (Small Integral Membrane Protein 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM22 Gene

Genomics for SMIM22 Gene

Genomic Location for SMIM22 Gene

Start:
4,788,397 bp from pter
End:
4,796,491 bp from pter
Size:
8,095 bases
Orientation:
Plus strand

Genomic View for SMIM22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMIM22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM22 Gene

No data available for Regulatory Elements for SMIM22 Gene

Proteins for SMIM22 Gene

  • Protein details for SMIM22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    K7EJ46-SIM22_HUMAN
    Recommended name:
    Small integral membrane protein 22
    Protein Accession:
    K7EJ46
    Secondary Accessions:
    • K7EIG5
    • K7EIH2

    Protein attributes for SMIM22 Gene

    Size:
    135 amino acids
    Molecular mass:
    14570 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SMIM22 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SMIM22 Gene

Proteomics data for SMIM22 Gene at MOPED

Post-translational modifications for SMIM22 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMIM22 Gene

Domains for SMIM22 Gene

Protein Domains for SMIM22 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM22: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM22 Gene

Function for SMIM22 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SMIM22 Gene

Localization for SMIM22 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM22 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM22: view

No data available for Subcellular locations from COMPARTMENTS for SMIM22 Gene

Pathways for SMIM22 Gene

SuperPathways for SMIM22 Gene

No Data Available

Interacting Proteins for SMIM22 Gene

Gene Ontology (GO) - Biological Process for SMIM22 Gene

None

No data available for Pathways by source for SMIM22 Gene

Transcripts for SMIM22 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM22

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM22 Gene

No ASD Table

Relevant External Links for SMIM22 Gene

GeneLoc Exon Structure for
SMIM22
ECgene alternative splicing isoforms for
SMIM22

Expression for SMIM22 Gene

mRNA expression in normal human tissues for SMIM22 Gene

mRNA differential expression in normal tissues according to GTEx for SMIM22 Gene

This gene is overexpressed in Colon - Transverse (13.0), Stomach (7.4), Pancreas (5.7), Small Intestine - Terminal Ileum (4.7), and Minor Salivary Gland (4.2).
genes like me logo Genes that share expressions with SMIM22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for SMIM22 Gene

Orthologs for SMIM22 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM22 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Smim22 35
  • 76.67 (n)
  • 72.5 (a)
Gm5480 16
Smim22 36
  • 67 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Smim22 35
  • 77.5 (n)
  • 72.5 (a)
zebrafish
(Danio rerio)
Actinopterygii SMIM22 36
  • 25 (a)
OneToOne
Species with no ortholog for SMIM22:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM22 Gene

ENSEMBL:
Gene Tree for SMIM22 (if available)
TreeFam:
Gene Tree for SMIM22 (if available)

Paralogs for SMIM22 Gene

No data available for Paralogs for SMIM22 Gene

Variants for SMIM22 Gene

Sequence variations from dbSNP and Humsavar for SMIM22 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1982514 -- 4,795,531(+) GGGTA(A/G)GGACC intron-variant
rs2075465 -- 4,796,067(+) GCCTC(C/T)GGGAC intron-variant
rs3085033 -- 4,793,109(-) ttttt(-/TT)gagac intron-variant
rs4360941 -- 4,794,548(+) cccta(C/G)tagct intron-variant, upstream-variant-2KB
rs7185700 -- 4,793,389(+) tggga(A/C)atgga intron-variant, upstream-variant-2KB

Relevant External Links for SMIM22 Gene

HapMap Linkage Disequilibrium report
SMIM22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM22 Gene

Disorders for SMIM22 Gene

No disorders were found for SMIM22 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SMIM22 Gene

Publications for SMIM22 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4

Products for SMIM22 Gene

Sources for SMIM22 Gene

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