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Aliases for SMIM20 Gene

Aliases for SMIM20 Gene

  • Small Integral Membrane Protein 20 2 3 5
  • C4orf52 3 4
  • Chromosome 4 Open Reading Frame 52 2

External Ids for SMIM20 Gene

Previous HGNC Symbols for SMIM20 Gene

  • C4orf52

Summaries for SMIM20 Gene

GeneCards Summary for SMIM20 Gene

SMIM20 (Small Integral Membrane Protein 20) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM20 Gene

Genomics for SMIM20 Gene

Regulatory Elements for SMIM20 Gene

Enhancers for SMIM20 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SMIM20 on UCSC Golden Path with GeneCards custom track

Promoters for SMIM20 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SMIM20 on UCSC Golden Path with GeneCards custom track

Genomic Location for SMIM20 Gene

Chromosome:
4
Start:
25,861,830 bp from pter
End:
25,929,879 bp from pter
Size:
68,050 bases
Orientation:
Plus strand

Genomic View for SMIM20 Gene

Genes around SMIM20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM20 Gene

Proteins for SMIM20 Gene

  • Protein details for SMIM20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N5G0-SMI20_HUMAN
    Recommended name:
    Small integral membrane protein 20
    Protein Accession:
    Q8N5G0
    Secondary Accessions:
    • C9JYT8
    • Q9BRT5

    Protein attributes for SMIM20 Gene

    Size:
    168 amino acids
    Molecular mass:
    18403 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH32431.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for SMIM20 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SMIM20 Gene

Proteomics data for SMIM20 Gene at MOPED

Post-translational modifications for SMIM20 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SMIM20 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM20 Gene

Domains & Families for SMIM20 Gene

Protein Domains for SMIM20 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM20: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM20 Gene

Function for SMIM20 Gene

Animal Model Products

miRNA for SMIM20 Gene

miRTarBase miRNAs that target SMIM20

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMIM20 Gene

Localization for SMIM20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM20 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMIM20 Gene

Pathways & Interactions for SMIM20 Gene

SuperPathways for SMIM20 Gene

No Data Available

Interacting Proteins for SMIM20 Gene

Gene Ontology (GO) - Biological Process for SMIM20 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM20 Gene

Drugs & Compounds for SMIM20 Gene

No Compound Related Data Available

Transcripts for SMIM20 Gene

Unigene Clusters for SMIM20 Gene

Small integral membrane protein 20:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM20 Gene

No ASD Table

Relevant External Links for SMIM20 Gene

GeneLoc Exon Structure for
SMIM20
ECgene alternative splicing isoforms for
SMIM20

Expression for SMIM20 Gene

mRNA expression in normal human tissues for SMIM20 Gene

Protein differential expression in normal tissues from HIPED for SMIM20 Gene

This gene is overexpressed in Stomach (18.8) and Bone (13.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SMIM20 Gene



SOURCE GeneReport for Unigene cluster for SMIM20 Gene Hs.479386

genes like me logo Genes that share expression patterns with SMIM20: view

Protein tissue co-expression partners for SMIM20 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SMIM20 Gene

Orthologs for SMIM20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM20 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SMIM20 35
  • 92.54 (n)
  • 100 (a)
SMIM20 36
  • 100 (a)
OneToMany
SMIM20 36
  • 100 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SMIM20 35
  • 89.55 (n)
  • 88.06 (a)
SMIM20 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Smim20 35
  • 88.89 (n)
  • 92.42 (a)
Smim20 16
Smim20 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia SMIM20 35
  • 99.5 (n)
  • 100 (a)
C4ORF52 36
  • 40 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Smim20 35
  • 85.86 (n)
  • 90.91 (a)
oppossum
(Monodelphis domestica)
Mammalia SMIM20 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMIM20 36
  • 47 (a)
OneToOne
chicken
(Gallus gallus)
Aves C4H4ORF52 35
  • 77.11 (n)
  • 76.12 (a)
C4H4ORF52 36
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SMIM20 36
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia smim20 35
  • 65.17 (n)
  • 67.16 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.3911 35
zebrafish
(Danio rerio)
Actinopterygii SMIM20 36
  • 56 (a)
OneToOne
Species with no ortholog for SMIM20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM20 Gene

ENSEMBL:
Gene Tree for SMIM20 (if available)
TreeFam:
Gene Tree for SMIM20 (if available)

Paralogs for SMIM20 Gene

No data available for Paralogs for SMIM20 Gene

Variants for SMIM20 Gene

Sequence variations from dbSNP and Humsavar for SMIM20 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
VAR_039965 -
VAR_039966 -
VAR_039967 -
VAR_039968 -
rs554 -- 25,929,703(+) GCACC(A/G)TGTTG utr-variant-3-prime

Variation tolerance for SMIM20 Gene

Gene Damage Index Score: 2.57; 44.64% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for SMIM20 Gene

Disorders for SMIM20 Gene

Relevant External Links for SMIM20

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMIM20

No disorders were found for SMIM20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM20 Gene

Publications for SMIM20 Gene

  1. MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly. (PMID: 26321642) Dennerlein S. … Rehling P. (Cell Rep 2015) 3 67
  2. A census of human soluble protein complexes. (PMID: 22939629) Havugimana P.C. … Emili A. (Cell 2012) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for SMIM20 Gene

Sources for SMIM20 Gene

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