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Aliases for SMIM19 Gene

Aliases for SMIM19 Gene

  • Small Integral Membrane Protein 19 2 3
  • C8orf40 3 4
  • Chromosome 8 Open Reading Frame 40 2
  • UPF0697 Protein C8orf40 3

External Ids for SMIM19 Gene

Previous HGNC Symbols for SMIM19 Gene

  • C8orf40

Previous GeneCards Identifiers for SMIM19 Gene

  • GC08P042397

Summaries for SMIM19 Gene

GeneCards Summary for SMIM19 Gene

SMIM19 (Small Integral Membrane Protein 19) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM19 Gene

Genomics for SMIM19 Gene

Genomic Location for SMIM19 Gene

Start:
42,541,155 bp from pter
End:
42,555,193 bp from pter
Size:
14,039 bases
Orientation:
Plus strand

Genomic View for SMIM19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMIM19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM19 Gene

No data available for Regulatory Elements for SMIM19 Gene

Proteins for SMIM19 Gene

  • Protein details for SMIM19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96E16-SMI19_HUMAN
    Recommended name:
    Small integral membrane protein 19
    Protein Accession:
    Q96E16
    Secondary Accessions:
    • B2R4S6
    • D3DSY4

    Protein attributes for SMIM19 Gene

    Size:
    107 amino acids
    Molecular mass:
    12439 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH13035.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAG34873.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for SMIM19 Gene

Proteomics data for SMIM19 Gene at MOPED

Post-translational modifications for SMIM19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for SMIM19 Gene

Domains for SMIM19 Gene

Protein Domains for SMIM19 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96E16

UniProtKB/Swiss-Prot:

SMI19_HUMAN :
  • Q96E16
Family:
  • Belongs to the SMIM19 family.
genes like me logo Genes that share domains with SMIM19: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SMIM19 Gene

Function for SMIM19 Gene

Phenotypes for SMIM19 Gene

GenomeRNAi human phenotypes for SMIM19:
genes like me logo Genes that share phenotypes with SMIM19: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SMIM19 Gene

Localization for SMIM19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM19 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM19: view

No data available for Subcellular locations from COMPARTMENTS for SMIM19 Gene

Pathways for SMIM19 Gene

SuperPathways for SMIM19 Gene

No Data Available

Interacting Proteins for SMIM19 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000390750%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000390750 for SMIM19 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for SMIM19 Gene

None

No data available for Pathways by source for SMIM19 Gene

Transcripts for SMIM19 Gene

Unigene Clusters for SMIM19 Gene

Small integral membrane protein 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM19 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: - - - - - -
SP2: - - - -
SP3: - - -
SP4: - - -
SP5: - -
SP6: -

Relevant External Links for SMIM19 Gene

GeneLoc Exon Structure for
SMIM19
ECgene alternative splicing isoforms for
SMIM19

Expression for SMIM19 Gene

mRNA expression in normal human tissues for SMIM19 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SMIM19 Gene

SOURCE GeneReport for Unigene cluster for SMIM19 Gene Hs.655320

genes like me logo Genes that share expressions with SMIM19: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SMIM19 Gene

Orthologs for SMIM19 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMIM19 35
  • 99.69 (n)
  • 100 (a)
SMIM19 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SMIM19 35
  • 85.36 (n)
  • 90.65 (a)
SMIM19 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SMIM19 35
  • 89.1 (n)
  • 91.59 (a)
SMIM19 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia AI316807 16
Smim19 35
  • 85.05 (n)
  • 85.98 (a)
Smim19 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SMIM19 36
  • 91 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMIM19 36
  • 90 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Smim19 35
  • 83.18 (n)
  • 83.18 (a)
chicken
(Gallus gallus)
Aves C4H8ORF40 35
  • 68.25 (n)
  • 66.67 (a)
C4H8ORF40 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SMIM19 36
  • 63 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.15169 35
tropical clawed frog
(Silurana tropicalis)
Amphibia smim19 35
  • 71.62 (n)
  • 76.24 (a)
Str.1870 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4407 35
zebrafish
(Danio rerio)
Actinopterygii SMIM19 36
  • 71 (a)
OneToOne
zgc:114040 35
  • 70.87 (n)
  • 72.82 (a)
Species with no ortholog for SMIM19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM19 Gene

ENSEMBL:
Gene Tree for SMIM19 (if available)
TreeFam:
Gene Tree for SMIM19 (if available)

Paralogs for SMIM19 Gene

No data available for Paralogs for SMIM19 Gene

Variants for SMIM19 Gene

Sequence variations from dbSNP and Humsavar for SMIM19 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs2923445 -- 42,545,600(+) ACCTC(A/C)GCTCA intron-variant
rs2923446 -- 42,549,034(+) CAAAA(A/G)GTGGA intron-variant
rs2923448 -- 42,550,865(+) gtgat(A/G)tattt intron-variant
rs2974343 -- 42,545,536(+) CTGTG(A/G)TTTTT intron-variant
rs2974344 -- 42,545,589(+) GCAAC(G/T)GCCTG intron-variant

Relevant External Links for SMIM19 Gene

HapMap Linkage Disequilibrium report
SMIM19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM19 Gene

Disorders for SMIM19 Gene

No disorders were found for SMIM19 Gene.

No data available for UniProtKB/Swiss-Prot for SMIM19 Gene

Publications for SMIM19 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for SMIM19 Gene

Sources for SMIM19 Gene

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