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Aliases for SMIM17 Gene

Aliases for SMIM17 Gene

  • Small Integral Membrane Protein 17 2 3

External Ids for SMIM17 Gene

Previous GeneCards Identifiers for SMIM17 Gene

  • GC19P057154

Summaries for SMIM17 Gene

GeneCards Summary for SMIM17 Gene

SMIM17 (Small Integral Membrane Protein 17) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM17 Gene

Genomics for SMIM17 Gene

Genomic Location for SMIM17 Gene

56,643,145 bp from pter
56,657,246 bp from pter
14,102 bases
Plus strand

Genomic View for SMIM17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for SMIM17 Gene

No data available for Regulatory Elements for SMIM17 Gene

Proteins for SMIM17 Gene

  • Protein details for SMIM17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Small integral membrane protein 17
    Protein Accession:

    Protein attributes for SMIM17 Gene

    118 amino acids
    Molecular mass:
    13332 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM17 Gene

Proteomics data for SMIM17 Gene at MOPED

Post-translational modifications for SMIM17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SMIM17 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM17 Gene

Domains & Families for SMIM17 Gene

Protein Domains for SMIM17 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM17: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM17 Gene

Function for SMIM17 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for SMIM17 Gene

Localization for SMIM17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM17 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM17: view

No data available for Subcellular locations from COMPARTMENTS for SMIM17 Gene

Pathways & Interactions for SMIM17 Gene

SuperPathways for SMIM17 Gene

No Data Available

Interacting Proteins for SMIM17 Gene

Gene Ontology (GO) - Biological Process for SMIM17 Gene


No data available for Pathways by source and SIGNOR curated interactions for SMIM17 Gene

Drugs & Compounds for SMIM17 Gene

No Compound Related Data Available

Transcripts for SMIM17 Gene

mRNA/cDNA for SMIM17 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMIM17 Gene

Small integral membrane protein 17:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM17 Gene

No ASD Table

Relevant External Links for SMIM17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SMIM17 Gene

mRNA expression in normal human tissues for SMIM17 Gene

mRNA differential expression in normal tissues according to GTEx for SMIM17 Gene

This gene is overexpressed in Brain - Hypothalamus (x7.0), Brain - Anterior cingulate cortex (BA24) (x5.9), and Brain - Frontal Cortex (BA9) (x5.4).

SOURCE GeneReport for Unigene cluster for SMIM17 Gene Hs.336588

genes like me logo Genes that share expression patterns with SMIM17: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for SMIM17 Gene

Orthologs for SMIM17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for SMIM17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SMIM17 35
  • 85.34 (n)
  • 80.17 (a)
(Canis familiaris)
Mammalia SMIM17 35
  • 87.07 (n)
  • 82.76 (a)
(Mus musculus)
Mammalia Gm16532 35
  • 86.54 (n)
  • 89.91 (a)
Smim17 16
Gm20715 36
  • 65 (a)
Smim17 36
  • 84 (a)
(Rattus norvegicus)
Mammalia Smim17 35
  • 86.54 (n)
  • 88.07 (a)
Species with no ortholog for SMIM17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM17 Gene

Gene Tree for SMIM17 (if available)
Gene Tree for SMIM17 (if available)

Paralogs for SMIM17 Gene

No data available for Paralogs for SMIM17 Gene

Variants for SMIM17 Gene

Sequence variations from dbSNP and Humsavar for SMIM17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1035117 -- 56,650,561(+) gagat(C/T)gttag intron-variant
rs1035118 -- 56,651,846(+) cgtct(A/G)taatc intron-variant
rs1861220 -- 56,654,251(+) GGGCA(A/T)GCATA intron-variant
rs1964273 -- 56,652,043(+) aggtt(A/G)caatg intron-variant
rs2870093 -- 56,648,377(+) ccatt(C/T)catcc intron-variant

Variation tolerance for SMIM17 Gene

Gene Damage Index Score: 1.33; 26.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMIM17 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM17 Gene

Disorders for SMIM17 Gene

Relevant External Links for SMIM17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with SMIM17: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM17 Gene

Publications for SMIM17 Gene

  1. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 67

Products for SMIM17 Gene

Sources for SMIM17 Gene

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