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Aliases for SMIM15 Gene

Aliases for SMIM15 Gene

  • Small Integral Membrane Protein 15 2 3
  • C5orf43 3 4
  • Chromosome 5 Open Reading Frame 43 2
  • UPF0542 Protein C5orf43 3

External Ids for SMIM15 Gene

Previous HGNC Symbols for SMIM15 Gene

  • C5orf43

Previous GeneCards Identifiers for SMIM15 Gene

  • GC05M060454

Summaries for SMIM15 Gene

GeneCards Summary for SMIM15 Gene

SMIM15 (Small Integral Membrane Protein 15) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM15 Gene

Genomics for SMIM15 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SMIM15 Gene

Start:
61,157,709 bp from pter
End:
61,162,475 bp from pter
Size:
4,767 bases
Orientation:
Minus strand

Genomic View for SMIM15 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMIM15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM15 Gene

No data available for Regulatory Elements for SMIM15 Gene

Proteins for SMIM15 Gene

  • Protein details for SMIM15 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3B0-SIM15_HUMAN
    Recommended name:
    Small integral membrane protein 15
    Protein Accession:
    Q7Z3B0
    Secondary Accessions:
    • B9EJC4

    Protein attributes for SMIM15 Gene

    Size:
    74 amino acids
    Molecular mass:
    8625 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SMIM15 Gene

Proteomics data for SMIM15 Gene at MOPED

Post-translational modifications for SMIM15 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SMIM15 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM15 Gene

Domains for SMIM15 Gene

Protein Domains for SMIM15 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q7Z3B0

UniProtKB/Swiss-Prot:

SIM15_HUMAN :
  • Q7Z3B0
Family:
  • Belongs to the SMIM15 family.
genes like me logo Genes that share domains with SMIM15: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for SMIM15 Gene

Function for SMIM15 Gene

Animal Model Products

CRISPR Products

miRNA for SMIM15 Gene

miRTarBase miRNAs that target SMIM15

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SMIM15 Gene

Localization for SMIM15 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM15 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SMIM15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM15: view

No data available for Subcellular locations from COMPARTMENTS for SMIM15 Gene

Pathways for SMIM15 Gene

SuperPathways for SMIM15 Gene

No Data Available

Interacting Proteins for SMIM15 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000339324%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000339324 for SMIM15 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for SMIM15 Gene

None

No data available for Pathways by source for SMIM15 Gene

Transcripts for SMIM15 Gene

mRNA/cDNA for SMIM15 Gene

(10) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMIM15 Gene

Small integral membrane protein 15:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM15

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SMIM15
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM15 Gene

No ASD Table

Relevant External Links for SMIM15 Gene

GeneLoc Exon Structure for
SMIM15
ECgene alternative splicing isoforms for
SMIM15

Expression for SMIM15 Gene

mRNA expression in normal human tissues for SMIM15 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SMIM15 Gene

SOURCE GeneReport for Unigene cluster for SMIM15 Gene Hs.508479

genes like me logo Genes that share expressions with SMIM15: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SMIM15 Gene

Orthologs for SMIM15 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM15 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMIM15 35
  • 100 (n)
  • 100 (a)
SMIM15 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H5orf43 35
  • 94.14 (n)
  • 98.65 (a)
SMIM15 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SMIM15 35
  • 94.59 (n)
  • 100 (a)
SMIM15 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Smim15 35
  • 91.44 (n)
  • 98.65 (a)
Smim15 16
Smim15 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SMIM15 36
  • 95 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMIM15 36
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Smim15 35
  • 90.09 (n)
  • 97.3 (a)
chicken
(Gallus gallus)
Aves CZH5ORF43 35
  • 78.83 (n)
  • 83.78 (a)
SMIM15 36
  • 84 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SMIM15 36
  • 94 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii smim15 35
  • 73.42 (n)
  • 90.54 (a)
smim15 36
  • 91 (a)
OneToOne
Species with no ortholog for SMIM15:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SMIM15 Gene

ENSEMBL:
Gene Tree for SMIM15 (if available)
TreeFam:
Gene Tree for SMIM15 (if available)

Paralogs for SMIM15 Gene

genes like me logo Genes that share paralogs with SMIM15: view

No data available for Paralogs for SMIM15 Gene

Variants for SMIM15 Gene

Sequence variations from dbSNP and Humsavar for SMIM15 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs298629 -- 61,157,335(+) TTGCT(C/T)TGTCG downstream-variant-500B
rs608487 -- 61,158,757(+) ATTGG(A/C)CCATG utr-variant-3-prime
rs1043204 -- 61,158,741(-) TATTC(A/C)CTGTT utr-variant-3-prime
rs2545503 -- 61,157,331(-) AGAGC(A/G)AGGCT downstream-variant-500B
rs4546328 - 61,160,105(+) TGTAA(A/G)GAAGC reference, missense

Relevant External Links for SMIM15 Gene

HapMap Linkage Disequilibrium report
SMIM15

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM15 Gene

Disorders for SMIM15 Gene

No disorders were found for SMIM15 Gene.

No data available for UniProtKB/Swiss-Prot for SMIM15 Gene

Publications for SMIM15 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for SMIM15 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SMIM15
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SMIM15
    • Block miRNA regulation of SMIM15 using miScript Target Protectors

    Sources for SMIM15 Gene

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