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Aliases for SMIM10 Gene

Subcategory (RNA class) for SMIM10 Gene

lncRNA

Aliases for SMIM10 Gene

  • Small Integral Membrane Protein 10 2 3 5
  • CXorf69 3 4
  • Chromosome X Open Reading Frame 69 2

External Ids for SMIM10 Gene

ORGUL Members for SMIM10 Gene

Previous HGNC Symbols for SMIM10 Gene

  • CXorf69

Previous GeneCards Identifiers for SMIM10 Gene

  • GC0XP134125

Summaries for SMIM10 Gene

GeneCards Summary for SMIM10 Gene

SMIM10 (Small Integral Membrane Protein 10) is a Protein Coding gene, and is affiliated with the lncRNA class. An important paralog of this gene is SMIM10L2A.

Additional gene information for SMIM10 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMIM10 Gene

Genomics for SMIM10 Gene

Regulatory Elements for SMIM10 Gene

Enhancers for SMIM10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH134989 1.3 Ensembl ENCODE 11.1 +0.2 223 2.4 ATF1 GLI4 ZNF2 ZNF121 ZNF766 GLIS2 ELK1 KLF7 ATF7 ZNF202 RTL8B ZNF75D SMIM10
GH0XH134965 1 Ensembl ENCODE 13.8 -25.4 -25437 0.6 CTCF ZNF384 RAD21 ZNF664 ZNF121 GATA3 GATA2 SMC3 ZNF143 PRDM10 SMIM10 RTL8A HMGB3P31
GH0XH134908 0.9 Ensembl ENCODE 12.1 -82.5 -82544 0.7 CTCF ZNF654 GATA2 SMC3 REST ZNF398 PRDM4 RAD21 SMIM10 MOSPD1 GC0XP134864
GH0XH134931 0.6 ENCODE 12.7 -57.5 -57529 2.9 SOX13 JUND FOXA2 SAP130 GLIS1 TCF7 MIER2 REST SMIM10 RNU6-616P GC0XM134919 LINC02243
GH0XH134963 0.2 ENCODE 13.7 -27.8 -27792 0.5 SMIM10 HMGB3P31
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SMIM10 on UCSC Golden Path with GeneCards custom track

Promoters for SMIM10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000248992 262 801 ATF1 GLI4 ZNF2 ZNF121 ZNF766 GLIS2 ELK1 KLF7 ATF7 ZNF202

Genomic Locations for SMIM10 Gene

Genomic Locations for SMIM10 Gene
chrX:134,990,938-134,992,473
(GRCh38/hg38)
Size:
1,536 bases
Orientation:
Plus strand
chrX:134,124,968-134,126,503
(GRCh37/hg19)

Genomic View for SMIM10 Gene

Genes around SMIM10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMIM10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMIM10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMIM10 Gene

Proteins for SMIM10 Gene

  • Protein details for SMIM10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96HG1-SIM10_HUMAN
    Recommended name:
    Small integral membrane protein 10
    Protein Accession:
    Q96HG1

    Protein attributes for SMIM10 Gene

    Size:
    83 amino acids
    Molecular mass:
    9236 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH08642.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for SMIM10 Gene

Post-translational modifications for SMIM10 Gene

No Post-translational modifications

Other Protein References for SMIM10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SMIM10 Gene

Domains & Families for SMIM10 Gene

Gene Families for SMIM10 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for SMIM10 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMIM10: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMIM10 Gene

Function for SMIM10 Gene

Phenotypes for SMIM10 Gene

GenomeRNAi human phenotypes for SMIM10:
genes like me logo Genes that share phenotypes with SMIM10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SMIM10 Gene

Localization for SMIM10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMIM10 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMIM10 gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 2
extracellular 1

Gene Ontology (GO) - Cellular Components for SMIM10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SMIM10: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for SMIM10 Gene

Pathways & Interactions for SMIM10 Gene

SuperPathways for SMIM10 Gene

No Data Available

Interacting Proteins for SMIM10 Gene

Gene Ontology (GO) - Biological Process for SMIM10 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMIM10 Gene

Drugs & Compounds for SMIM10 Gene

No Compound Related Data Available

Transcripts for SMIM10 Gene

mRNA/cDNA for SMIM10 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMIM10 Gene

Small integral membrane protein 10:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for SMIM10 Gene

No ASD Table

Relevant External Links for SMIM10 Gene

GeneLoc Exon Structure for
SMIM10
ECgene alternative splicing isoforms for
SMIM10

Expression for SMIM10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMIM10 Gene

mRNA differential expression in normal tissues according to GTEx for SMIM10 Gene

This gene is overexpressed in Artery - Tibial (x4.2).

Protein differential expression in normal tissues from HIPED for SMIM10 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for SMIM10 Gene



Protein tissue co-expression partners for SMIM10 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of SMIM10 Gene:

SMIM10

SOURCE GeneReport for Unigene cluster for SMIM10 Gene:

Hs.42239

Evidence on tissue expression from TISSUES for SMIM10 Gene

  • Eye(4)
genes like me logo Genes that share expression patterns with SMIM10: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMIM10 Gene

Orthologs for SMIM10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SMIM10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMIM10 34
  • 100 (a)
OneToOne
LOC100614576 33
  • 99.6 (n)
cow
(Bos Taurus)
Mammalia SMIM10 34
  • 78 (a)
OneToMany
-- 34
  • 68 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 69 (a)
OneToMany
-- 34
  • 63 (a)
OneToMany
-- 34
  • 62 (a)
OneToMany
mouse
(Mus musculus)
Mammalia 6330419J24Rik 34
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SMIM10 34
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves SMIM10 34
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 60 (a)
OneToMany
-- 34
  • 60 (a)
OneToMany
Species where no ortholog for SMIM10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMIM10 Gene

ENSEMBL:
Gene Tree for SMIM10 (if available)
TreeFam:
Gene Tree for SMIM10 (if available)

Paralogs for SMIM10 Gene

Paralogs for SMIM10 Gene

genes like me logo Genes that share paralogs with SMIM10: view

Variants for SMIM10 Gene

Sequence variations from dbSNP and Humsavar for SMIM10 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000713221 -- 134,991,831(+) CCCAA(C/T)TGAAT utr-variant-3-prime
rs1002215013 -- 134,990,821(+) GGAAG(C/T)TAGGT upstream-variant-2KB
rs1002568923 -- 134,990,169(+) TGTTC(A/G)CTGAA upstream-variant-2KB
rs1002928843 -- 134,992,039(+) TTGCC(A/G)AAAGT utr-variant-3-prime
rs1004186601 -- 134,990,030(+) TTTGA(C/T)CAATC upstream-variant-2KB

Variation tolerance for SMIM10 Gene

Gene Damage Index Score: 0.06; 1.47% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMIM10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMIM10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for SMIM10 Gene

Disorders for SMIM10 Gene

Relevant External Links for SMIM10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMIM10

No disorders were found for SMIM10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SMIM10 Gene

Publications for SMIM10 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for SMIM10 Gene

Sources for SMIM10 Gene

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