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SMG9 Gene

protein-coding   GIFtS: 43
GCID: GC19M044236

SMG9 Nonsense Mediated MRNA Decay Factor

(Previous names: chromosome 19 open reading frame 61, smg-9 homolog, nonsense...)
(Previous symbol: C19orf61)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SMG9 Nonsense Mediated MRNA Decay Factor1 2     Smg-9 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans)1
C19orf611 2 3 5     F17127_12
Protein Smg-9 Homolog2 3     Protein SMG92
Chromosome 19 Open Reading Frame 611     Smg-9 Homolog, Nonsense Mediated MRNA Decay Factor2

External Ids:    HGNC: 257631   Entrez Gene: 560062   Ensembl: ENSG000001057717   OMIM: 6131765   UniProtKB: Q9H0W83   

Export aliases for SMG9 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SMG9 Gene:
SMG9 (SMG9 nonsense mediated mRNA decay factor) is a protein-coding gene. GO annotations related to this gene include identical protein binding.

UniProtKB/Swiss-Prot: SMG9_HUMAN, Q9H0W8
Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by
release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and,
in the SMG1C complex, is required for the efficient association between SMG1 and SMG8




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SMG9
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSMG9 promoter sequence
   Search Chromatin IP Primers for SMG9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SMG9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.31   Ensembl cytogenetic band:  19q13.31   HGNC cytogenetic band: 19q13.31

SMG9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SMG9 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M044236:  view genomic region     (about GC identifiers)

Start:
44,235,301 bp from pter      End:
44,259,142 bp from pter
Size:
23,842 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SMG9_HUMAN, Q9H0W8 (See protein sequence)
Recommended Name: Protein SMG9  
Size: 520 amino acids; 57651 Da
Subunit: Component of the SMG1C complex composed of SMG1, SMG8 and SMG9. Self-associates to form homodimers and
forms heterodimers with SMG8; these assembly forms may represent SMG1C intermediate forms
Sequence caution: Sequence=AAC17932.1; Type=Erroneous gene model prediction;
Secondary accessions: O60429 Q9H9A9
Alternative splicing: 2 isoforms:  Q9H0W8-1   Q9H0W8-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SMG9: NX_Q9H0W8

Explore proteomics data for SMG9 at MOPED

Post-translational modifications: 

  • Phosphorylated by SMG11
  • Ubiquitination2 at Lys170
  • Modification sites at PhosphoSitePlus

  • See SMG9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_061981.2  
    ENSEMBL proteins: 
     ENSP00000270066   ENSP00000471398   ENSP00000471442   ENSP00000470451   ENSP00000472684  
     ENSP00000470031   ENSP00000468941   ENSP00000470541  
    Reactome Protein details: Q9H0W8

    SMG9 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019354 Smg8/Smg9

    Graphical View of Domain Structure for InterPro Entry Q9H0W8

    ProtoNet protein and cluster: Q9H0W8

    UniProtKB/Swiss-Prot: SMG9_HUMAN, Q9H0W8
    Similarity: Belongs to the SMG9 family


    Find genes that share domains with SMG9           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SMG9_HUMAN, Q9H0W8
    Function: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by
    release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and,
    in the SMG1C complex, is required for the efficient association between SMG1 and SMG8

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19417104
    GO:0042802identical protein binding IPI--
         
    Find genes that share ontologies with SMG9           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SMG9
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SMG9

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    2 qRT-PCR Assays for microRNAs that regulate SMG9:
    hsa-miR-370 hsa-miR-1291
    SwitchGear 3'UTR luciferase reporter plasmidSMG9 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat SMG9

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--
    GO:0005829cytosol TAS--

    Find genes that share ontologies with SMG9           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SMG9 About    
    See pathways by source

    SuperPathContained pathways About
    1Influenza Viral RNA Transcription and Replication
    Nonsense-Mediated Decay0.89
    Nonsense Mediated Decay Enhanced by the Exon Junction Complex0.89
    2Gene Expression
    Gene Expression0.40


    Find genes that share SuperPaths with SMG9           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for SMG9
        Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SMG9
    Interactions:

        Search GeneGlobe Interaction Network for SMG9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SMG9 (Q9H0W81 ENSP000002700664) via UniProtKB, MINT, STRING, and/or I2D (see all 74)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMG8Q8ND041, ENSP000003009174EBI-2872322,EBI-3903643 STRING: ENSP00000300917
    SMG9Q9H0W81EBI-2872322,EBI-2872322
    SMG1ENSP000004025154STRING: ENSP00000402515
    EIF4A3ENSP000002693494STRING: ENSP00000269349
    ETF1ENSP000003537414STRING: ENSP00000353741
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS--
    GO:0010467gene expression TAS--
    GO:0016070RNA metabolic process TAS--
    GO:0016071mRNA metabolic process TAS--

    Find genes that share ontologies with SMG9           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SMG9



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SMG9 gene: 
    NM_019108.2  

    Unigene Cluster for SMG9:

    Smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
    Hs.466875  [show with all ESTs]
    Unigene Representative Sequence: AK022948
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270066(uc002oxj.2 uc002oxk.2 uc010eiy.1) ENST00000600097
    ENST00000601170 ENST00000594081 ENST00000598860 ENST00000597598 ENST00000595700
    ENST00000602222 ENST00000597586 ENST00000601925 ENST00000599804 ENST00000596714
    ENST00000598886
    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate SMG9:
    hsa-miR-370 hsa-miR-1291
    SwitchGear 3'UTR luciferase reporter plasmidSMG9 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SMG9
    Predesigned siRNA for gene silencing in human, mouse, rat SMG9
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    GenScript Custom all cDNA clones Services for SMG9
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SMG9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMG9
    Primer
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    OriGene qPCR primer pairs and template standards for SMG9
    OriGene qSTAR qPCR primer pairs in human, mouse for SMG9
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SMG9
      QuantiTect SYBR Green Assays in human, mouse, rat SMG9
      QuantiFast Probe-based Assays in human, mouse, rat SMG9

    Additional mRNA sequence: 

    AK022948.1 AK309830.1 AL136606.1 BC008869.2 

    11 DOTS entries:

    DT.413229  DT.95147742  DT.100804910  DT.121495394  DT.100804904  DT.95360168  DT.100753702  DT.91742478 
    DT.121495391  DT.86845895  DT.99997111 

    Selected AceView cDNA sequences (see all 190):

    BQ054000 BX453604 F09576 CR606035 AI652907 BE501275 AI671901 AI652894 
    BM714782 BE208560 AA505782 BC008869 BQ216853 BF528046 BE390009 AJ430434 
    AI492899 AI339032 BM981890 AK022948 BM715791 AA889396 CD366067 AL540177 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SMG9 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a ·
    SP1:                    -     -     -     -     -                                                                                   -     -                     
    SP2:                    -     -     -     -     -                                                                                   -     -                     
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                    -     -     -     -     -                 -                                                                                             

    ExUns: 13b ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b ^ 17
    SP1:        -                             -         
    SP2:        -                                       
    SP3:                                                
    SP4:                                                
    SP5:                                                


    ECgene alternative splicing isoforms for SMG9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SMG9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAGCCTGAA
    SMG9 Expression
    About this image

    SMG9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SMG9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.466875
        Custom PCR Arrays for SMG9
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    QuantiFast Probe-based Assays in human, mouse, rat SMG9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMG9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SMG9 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Smg91 , 5 RIKEN cDNA 1500002O20 gene5
    smg-9 homolog, nonsense mediated mRNA decay factor more1
    88.14(n)1
    97.31(a)1
      7 (10.54 cM)5
    719971  NM_028047.21  NP_082323.11 
     243996195 
    lizard
    (Anolis carolinensis)
    Reptilia SMG96
    SMG9 nonsense mediated mRNA decay factor
    82(a)
    1 ↔ 1
    LGf(67565-77190)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.161892 Transcribed sequence with moderate similarity to protein more 75.61(n)    CF242158.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-79d12.31 si:dkey-79d12.3 69.77(n)
    75.91(a)
      562557  XM_001923780.4  XP_001923815.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG38576
    --
    23(a)
    1 ↔ 1
    X(1831733-1834073)
    worm
    (Caenorhabditis elegans)
    Secernentea smg-96
    Protein SMG-9 (smg-9) mRNA, complete cds
    22(a)
    1 ↔ 1
    II(14747273-14752489) WBGene00013188
    rice
    (Oryza sativa)
    Liliopsida Os06g01146001 Os06g0114600 47.68(n)
    33.54(a)
      4339915  NM_001063140.1  NP_001056605.1 


    ENSEMBL Gene Tree for SMG9 (if available)
    TreeFam Gene Tree for SMG9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SMG9 (see all 611)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3465491,2
    C--44234861(+) caggcA/Gtgcgc 1 -- int10--------
    rs1886698881,2
    C--44234940(+) GTCTCA/GAACTC 1 -- int10--------
    rs1459615841,2
    --44235129(+) TTTTCC/GCATCC 1 -- int10--------
    rs1927275151,2
    --44235148(+) CACAGG/TGGAGG 1 -- int10--------
    rs104235711,2
    C,H--44235152(+) GGGGAG/CGCTTG 1 -- int14Minor allele frequency- C:0.00NS EA 416
    rs1850904531,2
    --44235178(+) ACAGAA/CTAACC 1 -- int10--------
    rs1900723551,2
    --44235455(+) CCGGGC/GTTCCT 1 -- ut310--------
    rs96121,2
    C,F,A,H--44235517(+) GGGCTA/GCCCCA 1 -- ut3127Minor allele frequency- G:0.25MN NS EA NA WA CSA 3141
    rs126691,2
    C,F,A,H--44235535(+) TTTGGG/AGTGGG 1 -- ut31 ese320Minor allele frequency- A:0.20MN NS EA NA WA 2698
    rs3755718801,2
    C--44235580(+) GAGGGG/TGGGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for SMG9 (44235301 - 44259142 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for SMG9:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509745CNV Insertion20534489
    nsv833839CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SMG9
    DNA2.0 Custom Variant and Variant Library Synthesis for SMG9

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613176    OMIM disorders: --


    Find genes that share disorders with SMG9           About GenesLikeMe


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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SMG9 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with SMG9)
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    1. SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay. (PubMed id 19417104)1, 2, 3 Yamashita A.... Ohno S. (Genes Dev. 2009)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large- scale conformational changes controlled by SMG-8. (PubMed id 21245168)2 Arias-Palomo E.... Llorca O. (Genes Dev. 2011)
    7. Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex. (PubMed id 21640080)1 Takeda S....Konishi H. (Biochem. Biophys. Res. Commun. 2011)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Characterization of SMG-9, an essential component of the nonsense- mediated mRNA decay SMG1C complex. (PubMed id 20817927)2 Fernandez I.S.... Llorca O. (Nucleic Acids Res. 2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56006 HGNC: 25763 AceView: FLJ12886 Ensembl:ENSG00000105771 euGenes: HUgn56006
    ECgene: SMG9 H-InvDB: SMG9

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SMG9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SMG9 gene:
    Search GeneIP for patents involving SMG9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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