SMG5 Gene
protein-coding GIFtS: 51
GCID: GC01M156219
|
|
smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
| |
Aliases
for SMG5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Smg-5 Homolog, Nonsense Mediated MRNA Decay Factor (C. Elegans)1 2 | | LPTS-Interacting Protein2 3 | | EST1B1 2 3 5 | | RP11-54H19.71 | | LPTS-RP11 2 3 | | EST1 Telomerase Component Homolog B2 | | KIAA10891 3 5 | | Est1p-Like Protein B2 | | LPTSRP11 2 | | Ever Shorter Telomeres 1B2 | | SMG-51 2 | | LPTS Interacting Protein2 | | EST1-Like Protein B2 3 | | Protein SMG52 | | HSMG-51 | | SMG-5 Homolog3 |
Export aliases for SMG5 gene to outside databasesPrevious GC identifers: GC01M154485 GC01M127580 |
Summaries
for SMG5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SMG5:
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 (PubMed 14636577)).(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: SMG5_HUMAN, Q9UPR3Function: Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotesdephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involvingexonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1dephosphorylation. Necessary for TERT activity
Gene Wiki entry for SMG5
|
Genomic Views
for SMG5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SMG5 gene promoter:
SRF SRF (504 AA) Lmo2 Nkx2-5 CUTL1 YY1 Max PPAR-alpha PPAR-gamma1 HOXA5
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMG5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMG5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.2 Ensembl cytogenetic band: 1q22 HGNC cytogenetic band: 1q21SMG5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M156219: view genomic region
(about GC identifiers)
Start:
|
156,219,015 bp from pter |
End:
|
156,252,620 bp from pter |
Size:
|
33,606 bases |
Orientation:
|
minus strand |
|
Proteins
for SMG5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SMG5_HUMAN, Q9UPR3 (See
protein sequence)Recommended Name: Protein SMG5 Size: 1016 amino acids; 113928 Da
Subunit: Interacts with TERT, PPP2CA and SMG1. Part of a complex that contains SMG1, SMG5, SMG7, PPP2CA, a shortisoform of UPF3A (isoform UPF3AS, but not isoform UPF3AL) and phosphorylated UPF1. Not detected in complexes thatcontain unphosphorylated UPF1
Subcellular location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus andcytoplasm. Detected in cytoplasmic mRNA decay bodies
Sequence caution: Sequence=BAA83041.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from  and Proteopedia  for SMG5:2HWY (3D)
Secondary accessions: D3DVB7 Q5QJE7 Q659C7 Q8IXC0 Q8IY09 Q96IJ7Explore the universe of human proteins at neXtProt for SMG5: NX_Q9UPR3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UPR3
SMG5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_056142.2
ENSEMBL proteins: ENSP00000355261 ENSP00000400574 ENSP00000357250 Reactome Protein details: Q9UPR3
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SMG5 for ontologies About GeneDecksing
SMG5 Antibody Products:
Assay Products for SMG5: |
Protein
Domains /
Families
for SMG5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SMG5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UPR3ProtoNet protein and cluster: Q9UPR3 UniProtKB/Swiss-Prot: SMG5_HUMAN, Q9UPR3Similarity: Contains 1 PINc domain |
Function
for SMG5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SMG5_HUMAN, Q9UPR3Function: Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotesdephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involvingexonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1dephosphorylation. Necessary for TERT activity
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SMG5 (NM_015327) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMG5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMG5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMG5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SMG5 for ontologies About GeneDecksing
|
Pathways & Interactions
for SMG5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Synthesis of PB1-F2 | | | 2 | Metabolism of mRNA | | | 3 | Decay of mRNA in SMG6:SMG5:SMG7:mRNA Complex | | | 4 | Signaling events mediated by HDAC Class I | | | 5 | Regulation of Telomerase | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  BioSystems Pathways for SMG5
5/8 
Reactome Pathways for SMG5 (see all 8)
1 
Kegg Pathway (Kegg details for SMG5):
SMG5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SMG5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/142 Interacting proteins for SMG5 (Q9UPR31, 2, 3 ENSP000003552614) via UniProtKB, MINT, STRING, and/or I2D (see all 142)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SMG5 for ontologies About GeneDecksing
|
Drugs & Compounds
for SMG5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMG5
Search CenterWatch for drugs/clinical trials and news about SMG5
|
Transcripts
for SMG5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SMG5 gene: NM_015327.2 Unigene Cluster for SMG5: Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) Hs.516837 [show with all ESTs]Unigene Representative Sequence: BC0382968 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361813(uc001foc.4) ENST00000420555 ENST00000368267 ENST00000462362
ENST00000476954 ENST00000473643 ENST00000468993 ENST00000489907
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SMG5 (NM_015327) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMG5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMG5 |
Additional cDNA sequence: AB029012.2 AB085691.1 AK025988.1 AK026395.1 AK027486.1 AK092183.1 AL137738.1 AY168922.1 AY336728.1 BC007292.1 BC007453.2 BC038296.1 CR933677.1 20 DOTS entries: DT.442532 DT.40106647 DT.97847598 DT.92447184 DT.95122520 DT.100661546 DT.121384731 DT.75141513 DT.97847599 DT.100037536 DT.100795979 DT.100795987 DT.121610897 DT.40106648 DT.91669724 DT.92447180 DT.92447182 DT.97768450 DT.121609976 DT.40201439 24/312 AceView cDNA sequences (see all 312): BP378210 AA306366 CK000707 BM728292 BQ691980 BQ433906 AI953869 AW089787 CA411664 BE838744 AI682519 BU527452 BM808648 BU556974 BQ945966 AW168068 BE550730 BM800307 BE878104 AI022142 BE298449 AB085691 AW000913 BM800105
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SMG5 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c | ^ | 20 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 21 | ^ | 22 | ^ | 23 | ^ | 24a | · | 24b | ^ | 25 | ^ | 26a | · | 26b | · | 26c |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SMG5
|
Expression
for SMG5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SMG5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATAGCTCAG
About this image
See SMG5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SMG5
SOURCE GeneReport for Unigene cluster: Hs.516837
UniProtKB/Swiss-Prot: SMG5_HUMAN, Q9UPR3Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for SMG5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMG5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SMG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMG5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMG5 |
Orthologs
for SMG5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SMG5 gene from 6/20 species (see all 20) About this table
ENSEMBL Gene Tree for SMG5 (if available)
TreeFam Gene Tree for SMG5 (if available) |
Paralogs
for SMG5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SMG5 gene
- SMG72 SMG62
SMG5 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for SMG5
PGOHUM00000242487 PGOHUM00000249778
|
Genomic Variants
for SMG5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SMG5 (156219015 - 156252620 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SMG5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMG5 |
|
Disorders
/ Diseases
for SMG5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 SMG5 for disorders About MalaCards
SMG5 for disorders About GeneDecksing
OMIM gene information: 610962
OMIM disorders: --
Export disorders for SMG5 gene to outside databases
|
Publications
for SMG5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SMG5 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with SMG5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Functional conservation of the telomerase protein Est1p in humans. (PubMed id 12699629)1, 2, 3 Snow B.E....Harrington L. (2003)
- SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. (PubMed id 15546618)1, 2, 9 Unterholzner L. and Izaurralde E. (2004)
- Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. (PubMed id 14636577)1, 2, 9 Ohnishi T.... Ohno S. (2003)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex. (PubMed id 17053788)1, 2 Glavan F.... Conti E. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A human homolog of yeast est1 associates with telomerase and uncaps chromosome ends when overexpressed. (PubMed id 12676087)1, 3 Reichenbach P....Lingner J. (2003)
- Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
- Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
- SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. (PubMed id 15721257)1, 9 Fukuhara N....Conti E. (2005)
|
External Searches for SMG5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SMG5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SMG5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SMG5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SMG5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SMG5 gene:
Search GeneIP for patents involving SMG5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SMG5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SMG5 | | OriGene shRNA RFP for SMG5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMG5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMG5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SMG5 | | OriGene 3'-UTR Clone for SMG5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMG5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SMG5 | | OriGene Custom Protein Services for SMG5 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMG5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMG5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMG5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMG5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMG5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMG5 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SMG5 |
| |  |  |  |  | | | | |
 |
 |
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 | | | SMG5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMG5 |
|  |  |  | | | | Search ThermoFisher Antibodies for SMG5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMG5 |
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