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Aliases for SMEK3P Gene

Aliases for SMEK3P Gene

  • SMEK Homolog 3, Suppressor Of Mek1 (Dictyostelium) Pseudogene 2 3
  • FLFL3P 3
  • Smk1 3

External Ids for SMEK3P Gene

Previous GeneCards Identifiers for SMEK3P Gene

  • GC0XM027389
  • GC0XM025217

Summaries for SMEK3P Gene

GeneCards Summary for SMEK3P Gene

SMEK3P (SMEK Homolog 3, Suppressor Of Mek1 (Dictyostelium) Pseudogene) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMEK3P Gene

Genomics for SMEK3P Gene

Regulatory Elements for SMEK3P Gene

Genomic Location for SMEK3P Gene

Start:
27,460,211 bp from pter
End:
27,463,341 bp from pter
Size:
3,131 bases
Orientation:
Minus strand

Genomic View for SMEK3P Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SMEK3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMEK3P Gene

Proteins for SMEK3P Gene

  • Protein details for SMEK3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZMV5-SMEK3_HUMAN
    Recommended name:
    Putative SMEK homolog 3
    Protein Accession:
    Q6ZMV5
    Secondary Accessions:
    • Q96M31

    Protein attributes for SMEK3P Gene

    Size:
    832 amino acids
    Molecular mass:
    95776 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71482.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for SMEK3P Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SMEK3P Gene

Proteomics data for SMEK3P Gene at MOPED

Post-translational modifications for SMEK3P Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMEK3P Gene

Domains for SMEK3P Gene

Protein Domains for SMEK3P Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SMEK3P Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZMV5

UniProtKB/Swiss-Prot:

SMEK3_HUMAN :
  • Q6ZMV5
Family:
  • Belongs to the SMEK family.
genes like me logo Genes that share domains with SMEK3P: view

No data available for Gene Families for SMEK3P Gene

Function for SMEK3P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SMEK3P Gene

Localization for SMEK3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMEK3P Gene

Pathways for SMEK3P Gene

SuperPathways for SMEK3P Gene

No Data Available

Interacting Proteins for SMEK3P Gene

Gene Ontology (GO) - Biological Process for SMEK3P Gene

None

No data available for Pathways by source for SMEK3P Gene

Transcripts for SMEK3P Gene

mRNA/cDNA for SMEK3P Gene

(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMEK3P Gene

SMEK homolog 3, suppressor of mek1 (Dictyostelium) pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMEK3P Gene

No ASD Table

Relevant External Links for SMEK3P Gene

GeneLoc Exon Structure for
SMEK3P
ECgene alternative splicing isoforms for
SMEK3P

Expression for SMEK3P Gene

mRNA expression in normal human tissues for SMEK3P Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for SMEK3P Gene

This gene is overexpressed in Testis (53.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for SMEK3P Gene

SOURCE GeneReport for Unigene cluster for SMEK3P Gene Hs.350673

genes like me logo Genes that share expressions with SMEK3P: view

No data available for mRNA Expression by UniProt/SwissProt for SMEK3P Gene

Orthologs for SMEK3P Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for SMEK3P Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Smek3-ps 16
Species with no ortholog for SMEK3P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SMEK3P Gene

ENSEMBL:
Gene Tree for SMEK3P (if available)
TreeFam:
Gene Tree for SMEK3P (if available)

Paralogs for SMEK3P Gene

Selected SIMAP similar genes for SMEK3P Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SMEK3P: view

No data available for Paralogs for SMEK3P Gene

Variants for SMEK3P Gene

Sequence variations from dbSNP and Humsavar for SMEK3P Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2379032 -- 27,463,950(+) GTCTA(A/G)AAAAG upstream-variant-2KB
rs2379033 -- 27,464,175(+) AAAGA(A/G)ACTGT upstream-variant-2KB
rs3037842 -- 27,463,918(+) aaaaa(-/AA)GCGAG upstream-variant-2KB
rs4581202 -- 27,464,173(+) TAAAA(A/G)AGACT upstream-variant-2KB
rs5926443 -- 27,463,760(+) GTGGC(A/G)GGTGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SMEK3P Gene

Variant ID Type Subtype PubMed ID
esv25731 CNV Gain 19812545

Relevant External Links for SMEK3P Gene

HapMap Linkage Disequilibrium report
SMEK3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMEK3P Gene

Disorders for SMEK3P Gene

No disorders were found for SMEK3P Gene.

No data available for UniProtKB/Swiss-Prot for SMEK3P Gene

Publications for SMEK3P Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for SMEK3P Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate SMEK3P
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SMEK3P
    • Block miRNA regulation of SMEK3P using miScript Target Protectors

    Sources for SMEK3P Gene

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