Aliases for SMEK1 Gene
External Ids for SMEK1 Gene
Previous HGNC Symbols for SMEK1 Gene
Previous GeneCards Identifiers for SMEK1 Gene
GeneCards Summary for SMEK1 Gene
SMEK1 (SMEK Homolog 1, Suppressor Of Mek1 (Dictyostelium)) is a Protein Coding gene. Among its related pathways are Integrated Breast Cancer Pathway.
UniProtKB/Swiss-Prot for SMEK1 Gene
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.