SMEK1 Gene
protein-coding GIFtS: 53
GCID: GC14M091923
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|
SMEK homolog 1, suppressor of mek1 (Dictyostelium)(Previous name: KIAA2010 )
(Previous symbol: KIAA2010)
| |
Aliases
for SMEK1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SMEK Homolog 1, Suppressor Of Mek1 (Dictyostelium)1 2 | | FLJ207071 | | KIAA20101 2 3 | | MSTP0331 | | FLFL11 2 | | Serine/Threonine-Protein Phosphatase 4 Regulatory Subunit 3A2 | | Smk-11 | | PPP4R3A3 | | Smk11 | | SMEK Homolog 13 | | PP4R3A2 3 | | |
Export aliases for SMEK1 gene to outside databasesPrevious GC identifers: GC14M090994 GC14M072100 |
Summaries
for SMEK1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: P4R3A_HUMAN, Q6IN85Function: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C atcentrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFXphosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair
|
Genomic Views
for SMEK1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SMEK1 gene promoter:
Spz1 USF1 NRSF form 1 p300 NRSF form 2 PPAR-gamma1 NRF-2 USF-1 STAT3 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMEK1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMEK1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q32.12 Ensembl cytogenetic band: 14q32.12 HGNC cytogenetic band: 14q32.12SMEK1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M091923: view genomic region
(about GC identifiers)
Start:
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91,923,955 bp from pter |
End:
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91,976,898 bp from pter |
Size:
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52,944 bases |
Orientation:
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minus strand |
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Proteins
for SMEK1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: P4R3A_HUMAN, Q6IN85 (See
protein sequence)Recommended Name: Serine/threonine-protein phosphatase 4 regulatory subunit 3A Size: 833 amino acids; 95368 Da
Subunit: Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or moreregulatory subunits. Component of the PP4 complex PPP4C-PPP4R2-PPP4R3A. Interacts with PPP4C; the interaction requiresPPP4R2
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Nucleus. Note=In interphase localized in thecytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions
Sequence caution: Sequence=AAG39284.1; Type=Erroneous translation; Note=Wrong choice of frame; Sequence=BAA91960.1;Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA91960.1; Type=Miscellaneousdiscrepancy; Note=Probable intron retention; Sequence=BAB14877.1; Type=Erroneous initiation; Note=TranslationN-terminally extended; Sequence=BAC23106.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q69YK6 Q86U23 Q86YI7 Q8IVG1 Q9H3F1 Q9H7U8 Q9NV01 Q9NWP1Alternative splicing: 4 isoforms: Q6IN85-1 Q6IN85-2 Q6IN85-4 Q6IN85-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SMEK1: NX_Q6IN85
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6IN85
SMEK1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_115949.3
ENSEMBL proteins: ENSP00000450864 ENSP00000450883 ENSP00000450891 ENSP00000450473 ENSP00000452596 ENSP00000452257 ENSP00000451841 ENSP00000450432 ENSP00000451939 ENSP00000337125 ENSP00000392704
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SMEK1 for ontologies About GeneDecksing
SMEK1 Antibody Products:
Assay Products for SMEK1: |
Protein
Domains /
Families
for SMEK1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SMEK1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6IN85ProtoNet protein and cluster: Q6IN85 1 Blocks protein family: IPB008160 Collagen triple helix repeat
UniProtKB/Swiss-Prot: P4R3A_HUMAN, Q6IN85Similarity: Belongs to the SMEK familySimilarity: Contains 1 WH1 domain |
Function
for SMEK1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: P4R3A_HUMAN, Q6IN85Function: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C atcentrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFXphosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SMEK1 (NM_032560) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMEK1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMEK1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMEK1 |
2 GenomeRNAi human phenotypes for SMEK1:
|
Pathways & Interactions
for SMEK1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Integrated Breast Cancer Pathway | |
1  BioSystems Pathway for SMEK1
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SMEK1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/9 Interacting proteins for SMEK1 (Q6IN852, 3 ENSP000003371254) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006470 | protein dephosphorylation |
IEA | -- | | GO:0045722 | positive regulation of gluconeogenesis |
IEA | -- |
SMEK1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SMEK1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMEK1
Search CenterWatch for drugs/clinical trials and news about SMEK1 / P4R3A
|
Transcripts
for SMEK1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SMEK1 gene (2 alternative transcripts): NM_017936.3 NM_032560.4 Unigene Cluster for SMEK1: SMEK homolog 1, suppressor of mek1 (Dictyostelium) Hs.533887 [show with all ESTs]Unigene Representative Sequence: AB09593014 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000554684(uc001xzn.3 uc001xzo.3 uc010atz.3) ENST00000554943
ENST00000555462 ENST00000557382 ENST00000555718 ENST00000554308(uc001xzp.1)
ENST00000554390 ENST00000555029 ENST00000554574(uc001xzq.1) ENST00000555470
ENST00000557018 ENST00000554511 ENST00000337238(uc001xzm.3) ENST00000428424
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SMEK1 (NM_032560) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMEK1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMEK1 |
Additional cDNA sequence: AB095930.1 AF113213.1 AK024297.1 AL832921.1 BC018617.1 BC022778.1 BC028088.1 BC038932.1 BC072409.1 BX248247.1 10 DOTS entries: DT.100008024 DT.415842 DT.101984742 DT.100027396 DT.100799067 DT.430877 DT.100688981 DT.120759840 DT.120759873 DT.92434721 24/219 AceView cDNA sequences (see all 219): AA343927 AL696269 BI835430 BM970506 CA391914 BM981635 AA344775 BE535187 AV712139 AI620625 AA357864 BM802753 BM824424 BM853545 AA769111 BI768202 AL832921 BC022778 AA648949 AW050495 BM714277 AA345461 BM555380 BF969847
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SMEK1 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | · | 17d |
|---|
|
| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SMEK1
|
Expression
for SMEK1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SMEK1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGAGACTC
About this image
See SMEK1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SMEK1
SOURCE GeneReport for Unigene cluster: Hs.533887
SABiosciences Custom PCR Arrays for SMEK1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMEK1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SMEK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMEK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMEK1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMEK1 |
Orthologs
for SMEK1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SMEK1 gene from 9/30 species (see all 30) About this table
ENSEMBL Gene Tree for SMEK1 (if available)
TreeFam Gene Tree for SMEK1 (if available) |
Paralogs
for SMEK1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SMEK1 gene
- SMEK22
2 SIMAP similar genes for SMEK1 using alignment to 8 protein entries: P4R3A_HUMAN (see all proteins):SMEK2 SMEK3P
SMEK1 for paralogs About GeneDecksing
|
Genomic Variants
for SMEK1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SMEK1 (91923955 - 91976898 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SMEK1
1 CNV: 102010
1 Indel: 45310 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMEK1 |
|
Disorders
/ Diseases
for SMEK1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SMEK1 for disorders About GeneDecksing
OMIM gene information: 610351
OMIM disorders: --
2  diseases for SMEK1: About MalaCardshepatitis neuronitis
Export disorders for SMEK1 gene to outside databases
|
Publications
for SMEK1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SMEK1 gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with SMEK1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Depletion of protein phosphatase 4 in human cells reveals essential roles in centrosome maturation, cell migration and the regulation of Rho GTPases. (PubMed id 18487071)1, 2, 3 Martin-Granados C....Cohen P.T.W. (2008)
- A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. (PubMed id 16085932)1, 2, 3 Gingras A.-C.... Aebersold R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Tumor suppressor BLU enhances pro-apoptotic activity o f sMEK1 through physical interaction. (PubMed id 22349239)1 Dong S.M....Rho S.B. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Smek promotes histone deacetylation to suppress trans cription of Wnt target gene brachyury in pluripotent embryonic stem cells. (PubMed id 21423269)1 Lyu J....Lu W. (2011)
|
External Searches for SMEK1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SMEK1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SMEK1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SMEK1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SMEK1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SMEK1 gene:
Search GeneIP for patents involving SMEK1
Licensable Technologies for SMEK1 gene:GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SMEK1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SMEK1 | | OriGene shRNA RFP for SMEK1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMEK1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMEK1 | | | OriGene Protein Over-expression Lysate for SMEK1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SMEK1 | | OriGene 3'-UTR Clone for SMEK1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMEK1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SMEK1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SMEK1 | | OriGene Custom Protein Services for SMEK1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMEK1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMEK1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMEK1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMEK1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMEK1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMEK1 |
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 |  |  |  | |
| | | | Search Tocris compounds for SMEK1 |
| |  |  |  |  | | | | |
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 |
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 | | | SMEK1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMEK1 |
|  |  |  | | | | ThermoFisher Antibodies for SMEK1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMEK1 |
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