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Aliases for SMCR2 Gene

Subcategory (RNA class) for SMCR2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SMCR2 Gene

  • Smith-Magenis Syndrome Chromosome Region, Candidate 2 (Non-Protein Coding) 2 3 5
  • Smith-Magenis Syndrome Chromosome Region, Candidate 2 2
  • TCONS_00025215 3

External Ids for SMCR2 Gene

Previous GeneCards Identifiers for SMCR2 Gene

  • GC17U990313
  • GC17M017578

Summaries for SMCR2 Gene

GeneCards Summary for SMCR2 Gene

SMCR2 (Smith-Magenis Syndrome Chromosome Region, Candidate 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with SMCR2 include Smith-Magenis Syndrome.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMCR2 Gene

Genomics for SMCR2 Gene

Regulatory Elements for SMCR2 Gene

Enhancers for SMCR2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F017662 0.9 Ensembl ENCODE 5.1 +17.7 17673 1.9 HDGF ATF1 PKNOX1 WRNIP1 SIN3A YY1 FOS NFYC JUNB REST PEMT TOM1L2 SMCR2 ENSG00000273948 PIR47440
GH17F017675 1.1 Ensembl ENCODE 5 +4.8 4811 2.0 ARID4B KLF17 NFXL1 THRB RAD21 RARA ZNF366 SCRT2 THAP11 EGR2 TOM1L2 SMCR2 ENSG00000264885 ENSG00000274836
GH17F017680 0.2 ENCODE 4.8 -3.1 -3093 7.0 HDGF PKNOX1 WRNIP1 ZFP64 ARID4B SIN3A ZNF143 FOS ZNF263 SP3 TOM1L2 SMCR2 ENSG00000264885 RAI1 PIR55057
GH17F017677 0.6 Ensembl 0.8 +3.4 3402 0.4 ELF3 MLX ARID4B KLF17 NFXL1 THRB ZSCAN9 RAD21 YY1 RARA ENSG00000274836 SMCR2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SMCR2 on UCSC Golden Path with GeneCards custom track

Promoters for SMCR2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001534657 -998 2401 ATF1 ZFP64 ARID4B SIN3A BRCA1 GLIS2 ZNF143 FOS YY2 REST

Genomic Location for SMCR2 Gene

Chromosome:
17
Start:
17,674,026 bp from pter
End:
17,681,202 bp from pter
Size:
7,177 bases
Orientation:
Minus strand

Genomic View for SMCR2 Gene

Genes around SMCR2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMCR2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMCR2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMCR2 Gene

Proteins for SMCR2 Gene

Post-translational modifications for SMCR2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMCR2 Gene

Domains & Families for SMCR2 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SMCR2 Gene

Function for SMCR2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMCR2 Gene

Localization for SMCR2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMCR2 Gene

Pathways & Interactions for SMCR2 Gene

SuperPathways for SMCR2 Gene

No Data Available

Interacting Proteins for SMCR2 Gene

Gene Ontology (GO) - Biological Process for SMCR2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for SMCR2 Gene

Transcripts for SMCR2 Gene

mRNA/cDNA for SMCR2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SMCR2 Gene

No ASD Table

Relevant External Links for SMCR2 Gene

GeneLoc Exon Structure for
SMCR2
ECgene alternative splicing isoforms for
SMCR2

Expression for SMCR2 Gene

mRNA expression in normal human tissues for SMCR2 Gene

mRNA differential expression in normal tissues according to GTEx for SMCR2 Gene

This gene is overexpressed in Testis (x10.6).

NURSA nuclear receptor signaling pathways regulating expression of SMCR2 Gene:

SMCR2
genes like me logo Genes that share expression patterns with SMCR2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SMCR2 Gene

Orthologs for SMCR2 Gene

Evolution for SMCR2 Gene

ENSEMBL:
Gene Tree for SMCR2 (if available)
TreeFam:
Gene Tree for SMCR2 (if available)

No data available for Orthologs for SMCR2 Gene

Paralogs for SMCR2 Gene

No data available for Paralogs for SMCR2 Gene

Variants for SMCR2 Gene

Sequence variations from dbSNP and Humsavar for SMCR2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs10695432 -- 17,676,486(+) TGTGT(-/GT/TA)ATGTG intron-variant
rs11078394 -- 17,678,253(+) taaaT(A/T)AATTA upstream-variant-2KB
rs11078395 -- 17,678,257(+) taaat(A/T)aatta upstream-variant-2KB
rs111841324 -- 17,676,456(+) AAGGC(-/TGTGTG)TGTGT intron-variant
rs112374853 -- 17,675,140(+) AAAAT(-/A)CAAAA intron-variant

Relevant External Links for SMCR2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMCR2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for SMCR2 Gene

Disorders for SMCR2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SMCR2 Gene - From: GeneCards

Disorder Aliases PubMed IDs
smith-magenis syndrome
  • 17p11.2 microdeletion syndrome
- elite association - COSMIC cancer census association via MalaCards
Search SMCR2 in MalaCards View complete list of genes associated with diseases

Relevant External Links for SMCR2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMCR2
genes like me logo Genes that share disorders with SMCR2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMCR2 Gene

Publications for SMCR2 Gene

  1. Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. (PMID: 11997338) Bi W. … Lupski J.R. (Genome Res. 2002) 2 3 64

Products for SMCR2 Gene

Sources for SMCR2 Gene

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