Aliases for SMC2 Gene
External Ids for SMC2 Gene
Previous HGNC Symbols for SMC2 Gene
Previous GeneCards Identifiers for SMC2 Gene
GeneCards Summary for SMC2 Gene
SMC2 (Structural Maintenance Of Chromosomes 2) is a Protein Coding gene. Diseases associated with SMC2 include Smith-Mccort Dysplasia 2 and Pleural Empyema. Among its related pathways are ATM Pathway and Cell Cycle, Mitotic. GO annotations related to this gene include protein heterodimerization activity.
UniProtKB/Swiss-Prot for SMC2 Gene
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.