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Aliases for SMARCAL1 Gene

Aliases for SMARCAL1 Gene

  • SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1 2 3 5
  • HepA-Related Protein 2 3 4
  • Sucrose Nonfermenting Protein 2-Like 1 3 4
  • ATP-Driven Annealing Helicase 2 3
  • HHARP 3 4
  • HARP 3 4
  • SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A-Like Protein 1 3
  • SMARCA-Like Protein 1 3
  • EC 3.6.4.- 4
  • EC 3.6.1 61

External Ids for SMARCAL1 Gene

Previous GeneCards Identifiers for SMARCAL1 Gene

  • GC02P215378
  • GC02P215998
  • GC02P217241
  • GC02P217481
  • GC02P217102
  • GC02P216985
  • GC02P209131
  • GC02P217277

Summaries for SMARCAL1 Gene

Entrez Gene Summary for SMARCAL1 Gene

  • The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]

GeneCards Summary for SMARCAL1 Gene

SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1) is a Protein Coding gene. Diseases associated with SMARCAL1 include Schimke Immunoosseous Dysplasia and Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations. Among its related pathways are PEDF Induced Signaling and AMPK Enzyme Complex Pathway. GO annotations related to this gene include helicase activity and annealing helicase activity. An important paralog of this gene is ZRANB3.

UniProtKB/Swiss-Prot for SMARCAL1 Gene

  • ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

Gene Wiki entry for SMARCAL1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMARCAL1 Gene

Genomics for SMARCAL1 Gene

Regulatory Elements for SMARCAL1 Gene

Enhancers for SMARCAL1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G215653 1.5 FANTOM5 ENCODE dbSUPER 29 -758.3 -758251 1.3 ZFP64 ARID4B SLC30A9 ZNF202 TSHZ1 REST ZNF623 ZNF518A PPARG KAT8 SMARCAL1 RPL37A GC02M215662 ENSG00000227981
GH02G216497 1.1 ENCODE 32.5 +87.0 86978 3.8 FOXA2 MLX CREB3L1 ZFP64 WRNIP1 ARID4B SIN3A DMAP1 YBX1 ZNF2 SMARCAL1 LOC100507554 GC02M216502
GH02G216003 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.9 -406.9 -406917 3.8 HDGF FOXA2 PKNOX1 MLX WRNIP1 ZFP64 SIN3A ARID4B DMAP1 YY1 XRCC5 SMARCAL1 TNP1 IGFBP5 LINC01963 MREG GC02M216014 ENSG00000226276
GH02G216618 1.4 Ensembl ENCODE dbSUPER 13.7 +208.1 208072 3.3 HDGF FOXA2 ZNF2 YY1 TCF12 ZNF766 ZNF579 SMARCA4 NBN NR2C1 IGFBP2 SMARCAL1 ENSG00000236886 IGFBP5 PSMB3P2
GH02G216339 1.6 FANTOM5 Ensembl ENCODE dbSUPER 11.8 -69.4 -69360 7.7 CTCF PKNOX1 KLF1 FOXA2 RBBP5 ZIC2 RAD21 ETS1 ZFHX2 EGR1 MARCH4 ENSG00000235042 SMARCAL1 GC02P216342 GC02P216343 GC02P216352
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SMARCAL1 on UCSC Golden Path with GeneCards custom track

Promoters for SMARCAL1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000130053 186 1601 HDGF PKNOX1 FOXA2 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF766

Genomic Location for SMARCAL1 Gene

Chromosome:
2
Start:
216,412,414 bp from pter
End:
216,483,053 bp from pter
Size:
70,640 bases
Orientation:
Plus strand

Genomic View for SMARCAL1 Gene

Genes around SMARCAL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMARCAL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMARCAL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMARCAL1 Gene

Proteins for SMARCAL1 Gene

  • Protein details for SMARCAL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NZC9-SMAL1_HUMAN
    Recommended name:
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
    Protein Accession:
    Q9NZC9
    Secondary Accessions:
    • A6NEH0
    • Q53R00
    • Q96AY1
    • Q9NXQ5
    • Q9UFH3
    • Q9UI93

    Protein attributes for SMARCAL1 Gene

    Size:
    954 amino acids
    Molecular mass:
    105938 Da
    Quaternary structure:
    • Interacts with RPA2; the interaction is direct and mediates the recruitment by the RPA complex of SMARCAL1 to sites of DNA damage.
    SequenceCaution:
    • Sequence=BAA90955.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for SMARCAL1 Gene

neXtProt entry for SMARCAL1 Gene

Selected DME Specific Peptides for SMARCAL1 Gene

Q9NZC9:
  • PWGWDYS
  • VAVLSITAA
  • LLSGTPAMSRPAELYTQI
  • KFLVFAHH
  • PTFFPQFHAFGLRYC
  • LRRLKSDV
  • LADDMGLGKT
  • EAGLSETNFSEMTE
  • EWPLLVV
  • KTRKWSF
  • DESHFLKN
  • RFEFFDNWDSF
  • MGLGKTIQ
  • LVVVPSS
  • NRTAEAKI
  • PSSVRFTW
  • ELFWNPGVL
  • NIVSFDLL

Post-translational modifications for SMARCAL1 Gene

  • DNA damage-regulated phosphorylation by kinases that may include ATM, ATR and PRKDC.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for SMARCAL1 (SMARCAL1)

Domains & Families for SMARCAL1 Gene

Protein Domains for SMARCAL1 Gene

Suggested Antigen Peptide Sequences for SMARCAL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NZC9

UniProtKB/Swiss-Prot:

SMAL1_HUMAN :
  • Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
Family:
  • Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
genes like me logo Genes that share domains with SMARCAL1: view

No data available for Gene Families for SMARCAL1 Gene

Function for SMARCAL1 Gene

Molecular function for SMARCAL1 Gene

UniProtKB/Swiss-Prot Function:
ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks.

Enzyme Numbers (IUBMB) for SMARCAL1 Gene

Gene Ontology (GO) - Molecular Function for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004386 helicase activity IEA --
GO:0005515 protein binding IPI 19793862
GO:0005524 ATP binding IEA --
GO:0008094 DNA-dependent ATPase activity IMP 18974355
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with SMARCAL1: view
genes like me logo Genes that share phenotypes with SMARCAL1: view

Human Phenotype Ontology for SMARCAL1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SMARCAL1 Gene

MGI Knock Outs for SMARCAL1:

Animal Model Products

CRISPR Products

miRNA for SMARCAL1 Gene

miRTarBase miRNAs that target SMARCAL1

Inhibitory RNA Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for SMARCAL1 Gene

Localization for SMARCAL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMARCAL1 Gene

Nucleus. Note=Recruited to damaged DNA regions.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMARCAL1 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IDA 18974355
GO:0005654 nucleoplasm IDA --
GO:0005662 colocalizes_with DNA replication factor A complex IDA 19793862
GO:0035861 site of double-strand break IDA 19793862
genes like me logo Genes that share ontologies with SMARCAL1: view

Pathways & Interactions for SMARCAL1 Gene

genes like me logo Genes that share pathways with SMARCAL1: view

Pathways by source for SMARCAL1 Gene

1 Cell Signaling Technology pathway for SMARCAL1 Gene
1 BioSystems pathway for SMARCAL1 Gene

Gene Ontology (GO) - Biological Process for SMARCAL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000733 DNA strand renaturation IEA --
GO:0006259 DNA metabolic process IMP 18974355
GO:0006357 regulation of transcription from RNA polymerase II promoter IMP 18974355
GO:0006974 cellular response to DNA damage stimulus IMP 19793862
GO:0031297 replication fork processing TAS 27918544
genes like me logo Genes that share ontologies with SMARCAL1: view

No data available for SIGNOR curated interactions for SMARCAL1 Gene

Transcripts for SMARCAL1 Gene

Unigene Clusters for SMARCAL1 Gene

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMARCAL1 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1: -
SP2: - -
SP3:

Relevant External Links for SMARCAL1 Gene

GeneLoc Exon Structure for
SMARCAL1
ECgene alternative splicing isoforms for
SMARCAL1

Expression for SMARCAL1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMARCAL1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for SMARCAL1 Gene

This gene is overexpressed in CD8 Tcells (16.7), Peripheral blood mononuclear cells (16.1), Blymphocyte (10.3), CD4 Tcells (7.9), and Monocytes (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SMARCAL1 Gene



Protein tissue co-expression partners for SMARCAL1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of SMARCAL1 Gene:

SMARCAL1

SOURCE GeneReport for Unigene cluster for SMARCAL1 Gene:

Hs.516674

mRNA Expression by UniProt/SwissProt for SMARCAL1 Gene:

Q9NZC9-SMAL1_HUMAN
Tissue specificity: Ubiquitously expressed, with high levels in testis.

Evidence on tissue expression from TISSUES for SMARCAL1 Gene

  • Liver(4.1)
  • Lung(4.1)
  • Nervous system(2.5)

Phenotype-based relationships between genes and organs from Gene ORGANizer for SMARCAL1 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • endocrine
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • skeleton
  • urinary
Organs:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • jaw
  • larynx
  • mandible
  • maxilla
  • mouth
  • neck
  • nose
  • skull
  • thyroid
  • tongue
  • tooth
  • vocal cord
Thorax:
  • chest wall
  • clavicle
  • heart
  • heart valve
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Abdomen:
  • kidney
Pelvis:
  • pelvis
  • ureter
  • urinary bladder
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • blood
  • blood vessel
  • coagulation system
  • hair
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • spinal column
  • vertebrae
  • white blood cell
genes like me logo Genes that share expression patterns with SMARCAL1: view

Primer Products

No data available for mRNA differential expression in normal tissues for SMARCAL1 Gene

Orthologs for SMARCAL1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SMARCAL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMARCAL1 35 34
  • 99.69 (n)
OneToOne
dog
(Canis familiaris)
Mammalia SMARCAL1 34 35
  • 84.77 (n)
cow
(Bos Taurus)
Mammalia SMARCAL1 34 35
  • 81.96 (n)
rat
(Rattus norvegicus)
Mammalia Smarcal1 34
  • 80.68 (n)
mouse
(Mus musculus)
Mammalia Smarcal1 34 16 35
  • 80.16 (n)
oppossum
(Monodelphis domestica)
Mammalia SMARCAL1 35
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMARCAL1 35
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves SMARCAL1 34 35
  • 61.32 (n)
lizard
(Anolis carolinensis)
Reptilia SMARCAL1 35
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia smarcal1 34
  • 61.19 (n)
Str.11392 34
zebrafish
(Danio rerio)
Actinopterygii smarcal1 34 35
  • 66 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008426 34
  • 51.52 (n)
fruit fly
(Drosophila melanogaster)
Insecta Marcal1 34 35
  • 50.26 (n)
CG3753 36
  • 40 (a)
worm
(Caenorhabditis elegans)
Secernentea C16A3.1 34 35
  • 48.94 (n)
C16A3.1a 36
  • 37 (a)
C16A3.1b 36
  • 37 (a)
C16A3.1c 36
  • 37 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MOT1 35
  • 10 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons CHR18 34
  • 49.07 (n)
rice
(Oryza sativa)
Liliopsida Os07g0636200 34
  • 48.3 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2015 35
  • 44 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8418 34
Species where no ortholog for SMARCAL1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SMARCAL1 Gene

ENSEMBL:
Gene Tree for SMARCAL1 (if available)
TreeFam:
Gene Tree for SMARCAL1 (if available)

Paralogs for SMARCAL1 Gene

Paralogs for SMARCAL1 Gene

(1) SIMAP similar genes for SMARCAL1 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with SMARCAL1: view

Variants for SMARCAL1 Gene

Sequence variations from dbSNP and Humsavar for SMARCAL1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs119473036 Pathogenic, Schimke immuno-osseous dysplasia (SIOD) [MIM:242900] 216,435,495(+) CATCA(A/T)TGTAA reference, missense
rs119473037 Pathogenic, Schimke immuno-osseous dysplasia (SIOD) [MIM:242900] 216,450,927(+) TGCGG(C/T)GCCTC reference, missense
rs119473038 Pathogenic, Schimke immuno-osseous dysplasia (SIOD) [MIM:242900] 216,447,063(+) TGTCC(C/T)GGCCC reference, missense
rs200644381 Schimke immuno-osseous dysplasia (SIOD) [MIM:242900] 216,464,640(+) CAGAA(C/T)AGCTG reference, missense
rs200666300 Schimke immuno-osseous dysplasia (SIOD) [MIM:242900] 216,477,140(+) GCACC(A/G)CATTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for SMARCAL1 Gene

Variant ID Type Subtype PubMed ID
nsv1001603 CNV gain 25217958
nsv1004972 CNV gain 25217958
nsv1005697 CNV loss 25217958
nsv1006201 CNV gain 25217958
nsv3161 CNV insertion 18451855
nsv524480 CNV loss 19592680
nsv834537 CNV loss 17160897

Variation tolerance for SMARCAL1 Gene

Residual Variation Intolerance Score: 50.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.18; 75.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMARCAL1 Gene

Human Gene Mutation Database (HGMD)
SMARCAL1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMARCAL1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMARCAL1 Gene

Disorders for SMARCAL1 Gene

MalaCards: The human disease database

(9) MalaCards diseases for SMARCAL1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
schimke immunoosseous dysplasia
  • immunoosseous dysplasia, schimke type
spondyloepiphyseal dysplasia with congenital joint dislocations
  • chondrodysplasia with multiple dislocations
immune defect due to absence of thymus
  • nezelof syndrome
t cell deficiency
  • t-lymphocyte deficiency
skin papilloma
  • cutaneous papilloma
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

SMAL1_HUMAN
  • Schimke immuno-osseous dysplasia (SIOD) [MIM:242900]: An autosomal recessive pleiotropic disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction and immunodeficiency. Arteriosclerosis may also occur in some case. {ECO:0000269 PubMed:11799392, ECO:0000269 PubMed:18974355, ECO:0000269 PubMed:19793862}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for SMARCAL1

Genetic Association Database (GAD)
SMARCAL1
Human Genome Epidemiology (HuGE) Navigator
SMARCAL1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMARCAL1
genes like me logo Genes that share disorders with SMARCAL1: view

No data available for Genatlas for SMARCAL1 Gene

Publications for SMARCAL1 Gene

  1. Cloning and characterization of HARP/SMARCAL1: a prokaryotic HepA- related SNF2 helicase protein from human and mouse. (PMID: 10857751) Coleman M.A. … Mohrenweiser H.W. (Genomics 2000) 2 3 4 22 64
  2. The annealing helicase SMARCAL1 maintains genome integrity at stalled replication forks. (PMID: 19793861) Bansbach C.E. … Cortez D. (Genes Dev. 2009) 3 4 22 64
  3. The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart. (PMID: 19793862) Ciccia A. … Elledge S.J. (Genes Dev. 2009) 3 4 22 64
  4. The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA. (PMID: 19793863) Yusufzai T. … Kadonaga J.T. (Genes Dev. 2009) 3 4 22 64
  5. HARP is an ATP-driven annealing helicase. (PMID: 18974355) Yusufzai T. … Kadonaga J.T. (Science 2008) 2 3 4 64

Products for SMARCAL1 Gene

Sources for SMARCAL1 Gene

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