SMARCA5 Gene
protein-coding GIFtS: 59
GCID: GC04P144434
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|
SWI/SNF related, matrix associated, actin dependent regulator...
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Aliases
for SMARCA5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin,Subfamily A, Member 51 2 | | WCRF1352 3 | | HSNF2H1 | | SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A52 3 | | SNF2H2 3 5 | | Sucrose Nonfermenting-Like 52 | | ISWI1 2 | | SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of ChromatinSubfamily A Member 52 | | HISWI1 | | EC 3.6.4.-3 | | Sucrose Nonfermenting Protein 2 Homolog2 3 | | EC 3.6.18 |
Export aliases for SMARCA5 gene to outside databasesPrevious GC identifers: GC04P145230 GC04P144795 GC04P144900 GC04P145012 GC04P144792 GC04P144654 GC04P140164 |
Summaries
for SMARCA5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SMARCA5:
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicaseand ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structurearound those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factorRSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar insequence to the Drosophila ISWI chromatin remodeling protein. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SMCA5_HUMAN, O60264Function: Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also requiredfor replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays arole in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex thatmobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complexregulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription,mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structuresduring DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complexthat mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases,leading to heterochromatin formation and transcriptional silencing
Gene Wiki entry for SMARCA5
|
Genomic Views
for SMARCA5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SMARCA5 gene promoter:
Sp1 STAT5A Tal-1beta GATA-1 CREB Egr-2 NRF-2 deltaCREB IRF-7A ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMARCA5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMARCA5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q31.1-q31.2 Ensembl cytogenetic band: 4q31.21 HGNC cytogenetic band: 4q31.1-q31.2SMARCA5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P144434: view genomic region
(about GC identifiers)
Start:
|
144,434,616 bp from pter |
End:
|
144,478,639 bp from pter |
Size:
|
44,024 bases |
Orientation:
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plus strand |
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Proteins
for SMARCA5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SMCA5_HUMAN, O60264 (See
protein sequence)Recommended Name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 Size: 1052 amino acids; 121905 Da
Subunit: Catalytic subunit of the four known chromatin-remodeling complexes: CHRAC, RSF, ACF/WCRF, and WICH. Eachcomplex contains subunits which may regulate the specificity or catalytic activity of SMARCA5. ACF/WCRF containsBAZ1A; CHRAC contains BAZ1A, CHRAC1, and POLE3; RSF contains RSF1; WICH contains BAZ1B/WSTF. SMARCA5 is the catalyticsubunit of the NoRC chromatin-remodeling complex, which also contains BAZ2A/TIP5. The BAZ2A/TIP5 subunit of NoRC alsointeracts with DNMT1, DNMT3B and HDAC1, which allows NoRC to actively suppress rDNA transcription by a combination ofnucleosome remodeling, histone deacetylation, and DNA methylation. Catalytic subunit of SMARCA5/cohesin/NuRDcomplexes. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6,MYBBP1A and DDX21. Interacts with MYO1C (By similarity)
Subcellular location: Nucleus
Developmental stage: Overexpressed in CD34-positive erythrocyte progenitor cells in acute myeloid leukemia.Down-regulation correlates with hematologic remission following chemotherapyExplore the universe of human proteins at neXtProt for SMARCA5: NX_O60264
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60264
4/27 DME Specific Peptides for SMARCA5 (O60264) (see all 27)
SMARCA5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003592.3
ENSEMBL proteins: ENSP00000283131 Reactome Protein details: O60264
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
SMARCA5 for ontologies About GeneDecksing
SMARCA5 Antibody Products:
Assay Products for SMARCA5: |
Protein
Domains /
Families
for SMARCA5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SMARCA5 for domains About GeneDecksing
5/9 InterPro domains/families (see all 9):Graphical View of Domain Structure for InterPro Entry O60264ProtoNet protein and cluster: O60264 2 Blocks protein families: IPB000330 SNF2 related domain IPB002464 ATP-dependent helicase
UniProtKB/Swiss-Prot: SMCA5_HUMAN, O60264Similarity: Belongs to the SNF2/RAD54 helicase family. ISWI subfamilySimilarity: Contains 1 helicase ATP-binding domainSimilarity: Contains 1 helicase C-terminal domainSimilarity: Contains 2 SANT domains |
Function
for SMARCA5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SMCA5_HUMAN, O60264Function: Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also requiredfor replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays arole in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex thatmobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complexregulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription,mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structuresduring DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complexthat mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases,leading to heterochromatin formation and transcriptional silencing Genatlas biochemistry entry for SMARCA5:general transcriptional activator S cerevisiae SWI/SNF related protein,matrix associated,actin-dependent regulator ofchromatin,subfamily A,member 5,component of the chromatin remodeling complex,Drosophila ISWI (initiator of SWI)homolog,widely expressed
Enzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SMARCA5 (NM_003601) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMARCA5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMARCA5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMARCA5 |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
SMARCA5 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for SMARCA5: Smarca5tm1Ais Smarca5tm1.1Ais
6 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Smarca5):
SMARCA5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SMARCA5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RSF Complex Binds the Centromere. | | | 2 | Cell Cycle | | | 3 | BRCA1 Pathway | | | 4 | AMPK Enzyme Complex Pathway | | | 5 | Meiotic Synapsis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for SMARCA5
4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for SMARCA5
5 
Reactome Pathways for SMARCA5
SMARCA5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SMARCA5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/913 Interacting proteins for SMARCA5 (O602641, 2, 3 ENSP000002831314) via UniProtKB, MINT, STRING, and/or I2D (see all 913)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
SMARCA5 for ontologies About GeneDecksing
|
Drugs & Compounds
for SMARCA5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMARCA5
2 DrugBank Compounds for SMARCA5 About this table
Search CenterWatch for drugs/clinical trials and news about SMARCA5 / SMCA5
|
Transcripts
for SMARCA5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SMARCA5 gene: NM_003601.3 Unigene Cluster for SMARCA5: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 Hs.558422 [show with all ESTs]Unigene Representative Sequence: NM_0036013 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000283131(uc003ijg.3) ENST00000515531 ENST00000508573
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SMARCA5 (NM_003601) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SMARCA5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMARCA5 |
Additional cDNA sequence: AB010882.1 AF086544.1 AK123439.1 AK302841.1 AK308424.1 AK316444.1 AL157495.1 BC023144.1 17 DOTS entries: DT.119377 DT.100648167 DT.92443310 DT.100028947 DT.97817297 DT.102827757 DT.100786909 DT.100786902 DT.121220044 DT.75140788 DT.92443315 DT.92443317 DT.95079873 DT.121220063 DT.121220083 DT.95072957 DT.95079882 24/307 AceView cDNA sequences (see all 307): BM761795 AA743078 AU280259 AA370041 AA765329 NM_003601 CA442863 AA595337 BE221118 BM129764 AB010882 BC023144 AI371179 AL157495 CR596745 AI220908 BG054514 BF515148 AA831102 AI357485 BQ946124 BQ023735 AI373604 AL043913
GeneLoc Exon Structure
|
Expression
for SMARCA5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SMARCA5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAACTAGAAG
About this image
See SMARCA5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SMARCA5
SOURCE GeneReport for Unigene cluster: Hs.558422
UniProtKB/Swiss-Prot: SMCA5_HUMAN, O60264Tissue specificity: Ubiquitously expressed
SABiosciences Expression via Pathway-Focused PCR Arrays including SMARCA5: | Polycomb & Trithorax Complexes in human mouse rat | | Epigenetic Chromatin Remodeling Factors in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMARCA5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SMARCA5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMARCA5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMARCA5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMARCA5 |
Orthologs
for SMARCA5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SMARCA5 gene from 9/37 species (see all 37) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SMARCA51 |
SWI/SNF related, matrix associated, actin dependent more |
84.49(n)
97.48(a) |
|
422457 XM_001234485.2 XP_001234486.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SMARCA56 |
-- |
97(a) |
1 ↔ 1 |
5(118512476-118531855) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.88122 |
Xenopus laevis imitation switch ISWI (ISWI) mRNA, complete more |
82.56(n) |
|
AF292095.2 |
zebrafish
(Danio rerio) |
Actinopterygii |
smarca51 |
SWI/SNF related, matrix associated, actin dependent more |
74.86(n)
89.71(a) |
|
282615 NM_001081629.1 NP_001075098.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Iswi3 |
chromatin assembly/disassembly DNA dependent
adenosinetriphosphatase |
74(a) |
|
49B10 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
isw-16 |
Chromatin-remodeling complex ATPase chain isw-1 |
62(a) |
1 → many |
III(6703940-6710002) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
ISW11 |
Isw1p |
56.76(n)
53.3(a) |
|
852547 NP_009804.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CHR171 |
chromatin remodeling factor17 |
58.92(n)
57.54(a) |
|
831980 NM_121867.3 NP_568365.2 |
rice
(Oryza sativa) |
Liliopsida |
AK105265.12 |
-- |
74.66(n) |
|
AK105265.1 |
ENSEMBL Gene Tree for SMARCA5 (if available)
TreeFam Gene Tree for SMARCA5 (if available) |
Paralogs
for SMARCA5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SMARCA5 gene
- SMARCA12
18/19 SIMAP similar genes for SMARCA5 using alignment to 3 protein entries: SMCA5_HUMAN (see all proteins)
(see all similar genes):SMARCA1 INO80 CHD9 CHD8 CHD1L CHD5
HELLS SRCAP CHD2 CHD4 SMARCA4 ERCC6
CHD1 CHD3 SMARCAD1 BTAF1 DKFZp434K213 DKFZp434P202
SMARCA5 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for SMARCA5
PGOHUM00000232894 PGOHUM00000233506
|
Genomic Variants
for SMARCA5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SMARCA5
1 CNV: 3519 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMARCA5 |
|
Disorders
/ Diseases
for SMARCA5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SMARCA5 for disorders About GeneDecksing
OMIM gene information: 603375
OMIM disorders: --
13  diseases for SMARCA5: About MalaCardsprimitive neuroectodermal tumor neuroectodermal tumors williams syndrome conjunctivitis
acute leukemia prostate adenocarcinoma gastric cancer adenocarcinoma
sarcoma leukemia prostatitis thyroiditis
malaria
1 Novoseek disease relationship for SMARCA5 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| williams syndrome |
69.3 |
1 |
16514417 (1) |
Export disorders for SMARCA5 gene to outside databases
|
Publications
for SMARCA5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SMARCA5 gene, integrated from 9 sources (see all 105):
(articles sorted by number of sources associating them with SMARCA5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. (PubMed id 9730600)1, 2, 3, 9 Aihara T....Nakamura Y. (1998)
- An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. (PubMed id 12434153)1, 2, 9 Collins N....Varga-Weisz P.D. (2002)
- A chromatin remodelling complex that loads cohesin onto human chromosomes. (PubMed id 12198550)1, 2, 9 Hakimi M.-A.... Shiekhattar R. (2002)
- The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. (PubMed id 16603771)1, 2, 9 Cavellan E....Farrants A.K. (2006)
- The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. (PubMed id 15543136)1, 2, 9 Poot R.A....Varga-Weisz P.D. (2004)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Functional diversity of ISWI complexes. (PubMed id 15284901)1, 2 Dirscherl S.S. and Krebs J.E. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Functional analysis of the subunits of the chromatin assembly factor RSF. (PubMed id 12972596)1, 2 Loyola A.... Reinberg D. (2003)
- WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci. (PubMed id 11980720)1, 2 Bozhenok L.... Varga-Weisz P. (2002)
|
External Searches for SMARCA5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SMARCA5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SMARCA5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SMARCA5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SMARCA5 gene:
Search GeneIP for patents involving SMARCA5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SMARCA5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SMARCA5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SMARCA5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMARCA5 | | | OriGene Protein Over-expression Lysate for SMARCA5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SMARCA5 | | OriGene 3'-UTR Clone for SMARCA5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SMARCA5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SMARCA5 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SMARCA5 | | OriGene Custom Protein Services for SMARCA5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMARCA5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMARCA5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMARCA5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMARCA5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMARCA5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMARCA5 |
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| | | | Search Tocris compounds for SMARCA5 |
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 | | | SMARCA5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMARCA5 |
|  |  |  | | | | Search ThermoFisher Antibodies for SMARCA5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMARCA5 |
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