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SMARCA5 Gene(Protein Coding)

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5

GCID:
GC04P143513
GIFtS:
48

Aliases for SMARCA5 Gene

Aliases for SMARCA5 Gene

  • SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5 2 3 5
  • SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A5 3 4
  • Sucrose Nonfermenting Protein 2 Homolog 3 4
  • WCRF135 3 4
  • HSNF2H 3 4
  • SNF2H 3 4
  • SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 5 3
  • Sucrose Nonfermenting-Like 5 3
  • EC 3.6.4.- 4
  • EC 3.6.1 58
  • HISWI 3
  • ISWI 3

External Ids for SMARCA5 Gene

Previous GeneCards Identifiers for SMARCA5 Gene

  • GC04P145230
  • GC04P144795
  • GC04P144900
  • GC04P145012
  • GC04P144792
  • GC04P144654
  • GC04P144434
  • GC04P140164

Summaries for SMARCA5 Gene

Entrez Gene Summary for SMARCA5 Gene

  • The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for SMARCA5 Gene

SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 5) is a Protein Coding gene. Diseases associated with SMARCA5 include Extraskeletal Ewing Sarcoma and Williams-Beuren Syndrome. Among its related pathways are DNA Damage and DNA Double Strand Break Response. GO annotations related to this gene include nucleic acid binding and hydrolase activity. An important paralog of this gene is CHD1L.

UniProtKB/Swiss-Prot for SMARCA5 Gene

  • Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at Tyr-142, and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.

Gene Wiki entry for SMARCA5 Gene

Additional gene information for SMARCA5 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMARCA5 Gene

Genomics for SMARCA5 Gene

Regulatory Elements for SMARCA5 Gene

Enhancers for SMARCA5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H142695 1.1 ENCODE dbSUPER 11.3 -812.1 -812066 11 PKNOX1 INSM2 FEZF1 ZFHX2 GATA3 GLI2 ZSCAN5C EGR2 SCRT1 OVOL3 SMARCA5 INPP4B PIR53759 LOC105377457
GH04H143351 1.8 FANTOM5 Ensembl ENCODE dbSUPER 3 -156.1 -156107 11 FOXA2 FEZF1 GATA2 FOS ATF7 RUNX3 CAVIN1 JUNB ZNF592 MEF2D USP38 SMARCA5 GAB1 RPS2P20 RPSAP36
GH04H143512 1.3 ENCODE dbSUPER 0.7 +0.8 827 3 HDGF ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SP3 SP5 MXD4 GUSBP5 SMARCA5 SMARCA5-AS1
GH04H143230 0.5 FANTOM5 1.7 -282.6 -282553 0 JUNB BATF CREM GAB1 USP38 SMARCA5 FREM3 LOC105377623 ENSG00000250969
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around SMARCA5 on UCSC Golden Path with GeneCards custom track

Promoters for SMARCA5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000174152 1037 3401 HDGF ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SP3 SP5 MXD4

Genomic Location for SMARCA5 Gene

Chromosome:
4
Start:
143,513,463 bp from pter
End:
143,557,489 bp from pter
Size:
44,027 bases
Orientation:
Plus strand

Genomic View for SMARCA5 Gene

Genes around SMARCA5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMARCA5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMARCA5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMARCA5 Gene

Proteins for SMARCA5 Gene

  • Protein details for SMARCA5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60264-SMCA5_HUMAN
    Recommended name:
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
    Protein Accession:
    O60264

    Protein attributes for SMARCA5 Gene

    Size:
    1052 amino acids
    Molecular mass:
    121905 Da
    Quaternary structure:
    • Catalytic subunit of the four known chromatin-remodeling complexes: CHRAC, RSF, ACF/WCRF, and WICH. Each complex contains subunits which may regulate the specificity or catalytic activity of SMARCA5. ACF/WCRF contains BAZ1A; CHRAC contains BAZ1A, CHRAC1, and POLE3; RSF contains RSF1; WICH contains BAZ1B/WSTF. SMARCA5 is the catalytic subunit of the NoRC chromatin-remodeling complex, which also contains BAZ2A/TIP5. The BAZ2A/TIP5 subunit of NoRC also interacts with DNMT1, DNMT3B and HDAC1, which allows NoRC to actively suppress rDNA transcription by a combination of nucleosome remodeling, histone deacetylation, and DNA methylation. Catalytic subunit of SMARCA5/cohesin/NuRD complexes. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21. Interacts with MYO1C (By similarity). Interacts with BEND3.

neXtProt entry for SMARCA5 Gene

Selected DME Specific Peptides for SMARCA5 Gene

O60264:
  • PPKRERK
  • APFHQLR
  • DSDWNPQ
  • DDFDSWF
  • QAMDRAHR
  • IERGEARI
  • DEMGLGKT
  • PGEWDVCVTSYEM
  • QDFQFFP
  • IDEAHRIKNE
  • AGGLGINL
  • NRLLLTGTP
  • QTELFAHF
  • QRRCNTLI
  • NGILADE
  • TGTPLQN
  • HPYLFDG
  • RVLIFSQM
  • KSRTAME
  • DKLLPKL
  • LLNFLLPD
  • KRDFNQFIKANEK
  • MGLGKTL
  • RAHRIGQ
  • LDILEDY
  • ITDEDID
  • LSTRAGGLG

Post-translational modifications for SMARCA5 Gene

  • Ubiquitination at Lys132, isoforms=160, isoforms=176, Lys418, isoforms=430, isoforms=644, Lys647, isoforms=724, isoforms=836, and isoforms=847
  • Modification sites at PhosphoSitePlus

Other Protein References for SMARCA5 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • R&D Systems Antibodies for SMARCA5 (SMARCA5/SNF2H)
  • Cell Signaling Technology (CST) Antibodies for SMARCA5 (SMARCA5)

Domains & Families for SMARCA5 Gene

Gene Families for SMARCA5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Suggested Antigen Peptide Sequences for SMARCA5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O60264

UniProtKB/Swiss-Prot:

SMCA5_HUMAN :
  • Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
Family:
  • Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
genes like me logo Genes that share domains with SMARCA5: view

Function for SMARCA5 Gene

Molecular function for SMARCA5 Gene

GENATLAS Biochemistry:
general transcriptional activator S cerevisiae SWI/SNF related protein,matrix associated,actin-dependent regulator of chromatin,subfamily A,member 5,component of the chromatin remodeling complex,Drosophila ISWI (initiator of SWI) homolog,widely expressed
UniProtKB/Swiss-Prot Function:
Helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity. Complexes containing SMARCA5 are capable of forming ordered nucleosome arrays on chromatin; this may require intact histone H4 tails. Also required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A. Probably plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at Tyr-142, and is involved in the maintenance of chromatin structures during DNA replication processes. Essential component of the NoRC (nucleolar remodeling complex) complex, a complex that mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing.

Enzyme Numbers (IUBMB) for SMARCA5 Gene

Gene Ontology (GO) - Molecular Function for SMARCA5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IDA 12972596
GO:0004386 helicase activity TAS,IEA --
GO:0005515 protein binding IPI 10655480
GO:0005524 ATP binding IDA 12972596
genes like me logo Genes that share ontologies with SMARCA5: view
genes like me logo Genes that share phenotypes with SMARCA5: view

Animal Models for SMARCA5 Gene

MGI Knock Outs for SMARCA5:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SMARCA5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for SMARCA5 Gene

Localization for SMARCA5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SMARCA5 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for SMARCA5 gene
Compartment Confidence
nucleus 5
mitochondrion 3
cytosol 3
plasma membrane 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleus (3)
  • Nucleoli fibrillar center (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for SMARCA5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000793 condensed chromosome IDA 12972596
GO:0001650 fibrillar center IDA --
GO:0005634 nucleus IDA 12972596
GO:0005654 nucleoplasm TAS --
GO:0016589 NURF complex IDA 20850016
genes like me logo Genes that share ontologies with SMARCA5: view

Pathways & Interactions for SMARCA5 Gene

genes like me logo Genes that share pathways with SMARCA5: view

Gene Ontology (GO) - Biological Process for SMARCA5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006334 nucleosome assembly IDA 12972596
GO:0006338 chromatin remodeling IDA,TAS 9836642
GO:0006352 DNA-templated transcription, initiation IDA 9836642
GO:0006357 regulation of transcription from RNA polymerase II promoter TAS 9730600
GO:0016569 covalent chromatin modification IEA --
genes like me logo Genes that share ontologies with SMARCA5: view

No data available for SIGNOR curated interactions for SMARCA5 Gene

Drugs & Compounds for SMARCA5 Gene

(2) Drugs for SMARCA5 Gene - From: DrugBank

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
4-Deoxy-Alpha-D-Glucose Experimental Pharma Target 0
Beta-D-Glucose Experimental Pharma Target 0
genes like me logo Genes that share compounds with SMARCA5: view

Transcripts for SMARCA5 Gene

mRNA/cDNA for SMARCA5 Gene

Unigene Clusters for SMARCA5 Gene

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for SMARCA5
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for SMARCA5 Gene

No ASD Table

Relevant External Links for SMARCA5 Gene

GeneLoc Exon Structure for
SMARCA5
ECgene alternative splicing isoforms for
SMARCA5

Expression for SMARCA5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SMARCA5 Gene

Protein differential expression in normal tissues from HIPED for SMARCA5 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (17.7) and Lymph node (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for SMARCA5 Gene



Protein tissue co-expression partners for SMARCA5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of SMARCA5 Gene:

SMARCA5

SOURCE GeneReport for Unigene cluster for SMARCA5 Gene:

Hs.558422

mRNA Expression by UniProt/SwissProt for SMARCA5 Gene:

O60264-SMCA5_HUMAN
Tissue specificity: Ubiquitously expressed.

Evidence on tissue expression from TISSUES for SMARCA5 Gene

  • Liver(4.9)
  • Nervous system(4.9)
  • Lung(4.7)
  • Intestine(4.6)
  • Pancreas(4.6)
  • Skin(4.2)
  • Stomach(4)
  • Eye(3.9)
  • Kidney(3.8)
  • Thyroid gland(3.8)
  • Blood(3.7)
  • Muscle(2.9)
  • Heart(2.7)
  • Spleen(2.4)
genes like me logo Genes that share expression patterns with SMARCA5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for SMARCA5 Gene

Orthologs for SMARCA5 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SMARCA5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SMARCA5 34 33
  • 99.59 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SMARCA5 34
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SMARCA5 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SMARCA5 34 33
  • 94.33 (n)
OneToOne
cow
(Bos Taurus)
Mammalia SMARCA5 34 33
  • 92.59 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Smarca5 16 34 33
  • 91.84 (n)
rat
(Rattus norvegicus)
Mammalia Smarca5 33
  • 91.46 (n)
chicken
(Gallus gallus)
Aves SMARCA5 34 33
  • 84.53 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SMARCA5 34
  • 93 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia smarca5 33
  • 80.37 (n)
Str.5889 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.8812 33
zebrafish
(Danio rerio)
Actinopterygii smarca5 34 33
  • 75.41 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Iswi 34 35
  • 71 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea isw-1 34
  • 62 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ISW1 33
  • 57.01 (n)
ISW2 34
  • 45 (a)
OneToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F06710g 33
  • 55.65 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFL040W 33
  • 53.94 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons CHR11 33
  • 59.06 (n)
soybean
(Glycine max)
eudicotyledons Gma.10074 33
rice
(Oryza sativa)
Liliopsida Os01g0367900 33
  • 60.3 (n)
barley
(Hordeum vulgare)
Liliopsida Hv.12926 33
wheat
(Triticum aestivum)
Liliopsida Ta.3492 33
corn
(Zea mays)
Liliopsida Zm.10239 33
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6886 34
  • 72 (a)
OneToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU03875 33
  • 54.17 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.1499 33
Species where no ortholog for SMARCA5 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for SMARCA5 Gene

ENSEMBL:
Gene Tree for SMARCA5 (if available)
TreeFam:
Gene Tree for SMARCA5 (if available)

Paralogs for SMARCA5 Gene

Paralogs for SMARCA5 Gene

Pseudogenes.org Pseudogenes for SMARCA5 Gene

genes like me logo Genes that share paralogs with SMARCA5: view

Variants for SMARCA5 Gene

Sequence variations from dbSNP and Humsavar for SMARCA5 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000003044 -- 143,520,792(+) GCTCT(C/T)AAGGT intron-variant
rs1000015688 -- 143,519,214(+) AATTC(A/G)TAATT intron-variant
rs1000094611 -- 143,533,538(+) AGTCT(A/C)GCTCT intron-variant
rs1000131652 -- 143,551,103(+) CATTT(C/T)ATCTG intron-variant
rs1000163694 -- 143,529,697(+) TCCAT(A/G)TTAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SMARCA5 Gene

Variant ID Type Subtype PubMed ID
esv2759288 CNV gain+loss 17122850
nsv830103 CNV loss 17160897
nsv964101 CNV duplication 23825009

Variation tolerance for SMARCA5 Gene

Residual Variation Intolerance Score: 4.43% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.36; 7.98% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SMARCA5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMARCA5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SMARCA5 Gene

Disorders for SMARCA5 Gene

MalaCards: The human disease database

(2) MalaCards diseases for SMARCA5 Gene - From: Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
extraskeletal ewing sarcoma
  • extraosseous ewing sarcoma
williams-beuren syndrome
  • fanconi schlesinger syndrome
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SMARCA5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMARCA5
genes like me logo Genes that share disorders with SMARCA5: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMARCA5 Gene

Publications for SMARCA5 Gene

  1. Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. (PMID: 9730600) Aihara T … Nakamura Y (Cytogenetics and cell genetics 1998) 2 3 4 22 60
  2. The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. (PMID: 16603771) Cavellán E … Farrants AK (The Journal of biological chemistry 2006) 3 4 22 60
  3. The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. (PMID: 15543136) Poot RA … Varga-Weisz PD (Nature cell biology 2004) 3 4 22 60
  4. A chromatin remodelling complex that loads cohesin onto human chromosomes. (PMID: 12198550) Hakimi MA … Shiekhattar R (Nature 2002) 3 4 22 60
  5. An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin. (PMID: 12434153) Collins N … Varga-Weisz PD (Nature genetics 2002) 3 4 22 60

Products for SMARCA5 Gene

Sources for SMARCA5 Gene

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