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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SMAP2 Gene

protein-coding   GIFtS: 51
GCID: GC01P040810

Small ArfGAP2

(Previous names: stromal membrane-associated protein 1-like, stromal membrane-associated...)
(Previous symbol: SMAP1L)
  Search for SMAP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Small ArfGAP21 2     RP1-228H13.32
SMAP1L1 2 3     Stromal Membrane-Associated Protein 22
Stromal Membrane-Associated GTPase-Activating Protein 21 2     SMOC25
Stromal Membrane-Associated Protein 1-Like1 3     

External Ids:    HGNC: 250821   Entrez Gene: 647442   Ensembl: ENSG000000840707   OMIM: 6072235   UniProtKB: Q8WU793   

Export aliases for SMAP2 gene to outside databases

Previous GC identifers: GC01P040614 GC01P038958


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SMAP2 Gene: 
SMAP2 (small ArfGAP2) is a protein-coding gene. GO annotations related to this gene include ARF GTPase activator activity and zinc ion binding. An important paralog of this gene is SMAP1.

UniProtKB/Swiss-Prot: SMAP2_HUMAN, Q8WU79
Function: GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in
clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SMAP2 gene promoter:
         c-Fos   AP-1   AML1a   p53   FosB   CREB   FOXJ2 (long isoform)   deltaCREB   c-Jun   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SMAP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SMAP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMAP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.3-p34.1   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p35.3-p34.1

SMAP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SMAP2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P040810:  view genomic region     (about GC identifiers)

Start:
40,810,522 bp from pter      End:
40,888,998 bp from pter
Size:
78,477 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SMAP2_HUMAN, Q8WU79 (See protein sequence)
Recommended Name: Stromal membrane-associated protein 2  
Size: 429 amino acids; 46786 Da
Subunit: Interacts with ARF1. Interacts with PICALM and clathrin heavy chains (By similarity)
Subcellular location: Cytoplasm. Note=Detected in multiple foci throughout the cytoplasm and in juxtanuclear
structures (By similarity)
1 PDB 3D structure from and Proteopedia for SMAP2:
2IQJ (3D)    
Secondary accessions: B2R7T1 B7Z5B5 B7Z8V2 D3DPV2 Q5QPL2 Q96C93 Q9NST2 Q9UJL8
Alternative splicing: 3 isoforms:  Q8WU79-1   Q8WU79-2   Q8WU79-3   

Explore the universe of human proteins at neXtProt for SMAP2: NX_Q8WU79

Explore proteomics data for SMAP2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WU79

  • SMAP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SMAP2 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001185907.1  NP_001185908.1  NP_001185909.1  NP_073570.1  

    ENSEMBL proteins: 
     ENSP00000389895   ENSP00000361803   ENSP00000361793   ENSP00000442835  

    Human Recombinant Protein Products for SMAP2: 
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    OriGene Custom MassSpec 
    OriGene Custom Protein Services for SMAP2
    GenScript Custom Purified and Recombinant Proteins Services for SMAP2
    Novus Biologicals SMAP2 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SMAP2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    SMAP2 for ontologies           About GeneDecksing



    SMAP2 Antibody Products: 
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    Cloud-Clone Corp. Antibodies for SMAP2 
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    LSBio Antibodies in human, mouse, rat for SMAP2 

    Assay Products for SMAP2: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SMAP2 
    Cloud-Clone Corp. CLIAs for SMAP2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ArfGAP: ADP-ribosylation factor GTPase activating proteins

    1 InterPro protein domain:
     IPR001164 ArfGAP

    Graphical View of Domain Structure for InterPro Entry Q8WU79

    ProtoNet protein and cluster: Q8WU79

    1 Blocks protein domain: IPB001164 HIV Rev interacting protein signature

    UniProtKB/Swiss-Prot: SMAP2_HUMAN, Q8WU79
    Similarity: Contains 1 Arf-GAP domain


    SMAP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SMAP2_HUMAN, Q8WU79
    Function: GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in
    clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008060ARF GTPase activator activity IEA--
    GO:0008270zinc ion binding IEA--
         
    SMAP2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SMAP2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SMAP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SMAP2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SMAP2 

    miRNA
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    8/35 QIAGEN miScript miRNA Assays for microRNAs that regulate SMAP2 (see all 35):
    hsa-let-7d hsa-miR-15a hsa-miR-218-1* hsa-miR-578 hsa-let-7g hsa-miR-9 hsa-miR-424 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidSMAP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SMAP2
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    Gene Editing
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    Clone
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    OriGene clones in human, mouse for SMAP2 (see all 13)
    OriGene ORF clones in mouse, rat for SMAP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SMAP2 (NM_001198979)
    Browse Sino Biological Human cDNA Clones
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                         Customized lentivirus expression plasmids for stable overexpression of SMAP2 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMAP2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SMAP2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Endocytosis
    Endocytosis

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for SMAP2):
        Endocytosis


    SMAP2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SMAP2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for SMAP2 (ENSP000003618034) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MRGBPENSP000003595184STRING: ENSP00000359518
    TTC4ENSP000003603294STRING: ENSP00000360329
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032312regulation of ARF GTPase activity IEA--

    SMAP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SMAP2

    Search CenterWatch for drugs/clinical trials and news about SMAP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SMAP2 gene (4 alternative transcripts): 
    NM_001198978.1  NM_001198979.1  NM_001198980.1  NM_022733.2  

    Unigene Cluster for SMAP2:

    Small ArfGAP2
    Hs.15200  [show with all ESTs]
    Unigene Representative Sequence: NM_022733
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000435168 ENST00000372718(uc010ojh.2 uc001cfj.3) ENST00000372708(uc001cfk.3 uc021oma.1 uc010oji.2 uc010ojj.2)
    ENST00000487871 ENST00000539317
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SMAP2
    8/35 QIAGEN miScript miRNA Assays for microRNAs that regulate SMAP2 (see all 35):
    hsa-let-7d hsa-miR-15a hsa-miR-218-1* hsa-miR-578 hsa-let-7g hsa-miR-9 hsa-miR-424 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidSMAP2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SMAP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMAP2
    Clone
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    OriGene clones in human, mouse for SMAP2 (see all 13)
    OriGene ORF clones in mouse, rat for SMAP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SMAP2 (NM_001198979)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SMAP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SMAP2
    Sirion Biotech Customized lentivirus for stable overexpression of SMAP2 
                         Customized lentivirus expression plasmids for stable overexpression of SMAP2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SMAP2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMAP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMAP2

    Additional mRNA sequence: 

    AK294675.1 AK298702.1 AK303975.1 AK308280.1 AK313105.1 AK316218.1 AL133206.1 AL137764.1 
    BC014512.1 BC021133.1 

    22 DOTS entries:

    DT.95084422  DT.100788986  DT.100788985  DT.91871563  DT.95084424  DT.121455548  DT.121455570  DT.91709282 
    DT.91798780  DT.91928820  DT.95084426  DT.100743993  DT.75185348  DT.92429819  DT.95316147  DT.95362284 
    DT.100676060  DT.121455536  DT.75123591  DT.91654083  DT.95084427  DT.97854429 

    24/215 AceView cDNA sequences (see all 215):

    Z43969 BQ719655 AL133206 BC014512 AI288517 AA872328 BE465267 CA312506 
    BM977398 BC021133 CA436192 NM_022733 CB529519 BX282026 AI298661 AW102984 
    AI874260 AL137764 BF110646 T30306 AW467220 BE467296 BU684731 BM477933 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SMAP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTGGGAACC
    SMAP2 Expression
    About this image


    See SMAP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SMAP2

    SOURCE GeneReport for Unigene cluster: Hs.15200
        SABiosciences Custom PCR Arrays for SMAP2
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMAP2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMAP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SMAP2 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Smap21 , 5 stromal membrane-associated GTPase-activating protein more1, 5 91.59(n)1
    95.79(a)1
      4 (56.70 cM)5
    697801  NM_133716.31  NP_598477.21 
     1209683175 
    chicken
    (Gallus gallus)
    Aves SMAP21 small ArfGAP2 77(n)
    80.05(a)
      419641  NM_001030902.1  NP_001026073.1 
    lizard
    (Anolis carolinensis)
    Reptilia SMAP26
    Uncharacterized protein
    79(a)
    1 ↔ 1
    GL343308.1(98878-121975)
    zebrafish
    (Danio rerio)
    Actinopterygii smap21 small ArfGAP2 61.85(n)
    59.8(a)
      556132  NM_001044795.1  NP_001038260.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG82436
    --
    27(a)
    1 → many
    2R(4810290-4812851)
    worm
    (Caenorhabditis elegans)
    Secernentea W09D10.16
    Protein W09D10.1
    25(a)
    1 → many
    III(10736893-10739794)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes AGE2(YIL044C)4 ADP-ribosylation factor (ARF) GTPase activating protein more   --   9(273846-272950) 854767  NP_012220.1 
    barley
    (Hordeum vulgare)
    Liliopsida BG300565.12   -- 72.1(n)    BG300565.1 


    ENSEMBL Gene Tree for SMAP2 (if available)
    TreeFam Gene Tree for SMAP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SMAP2 gene
    SMAP12  ADAP22  ADAP12  
    2 SIMAP similar genes for SMAP2 using alignment to 1 protein entry:     SMAP2_HUMAN:
    ARFGAP1    SMAP1

    SMAP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1039 SNPs in SMAP2 are shown (see all 1039)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs112079641,2
    C,F,H--40837481(+) attatA/Gttaca 1 -- us2k114Minor allele frequency- G:0.05NS EA NA WA 1888
    rs1887620371,2
    --40837582(+) GGCACC/GAAGAG 1 -- us2k10--------
    rs1807310991,2
    --40837654(+) AAGCAC/TTCTTG 1 -- us2k10--------
    rs1852480291,2
    --40837708(+) ACTAGG/TTGGGA 1 -- us2k10--------
    rs1431374221,2
    --40837742(+) GGCAAC/TGGAGA 1 -- us2k10--------
    rs1884720521,2
    --40837809(+) AGCTCA/CCTCTA 1 -- us2k10--------
    rs1820695441,2
    --40837823(+) AGCACC/GGTGAA 1 -- us2k10--------
    rs1874296601,2
    --40837832(+) AAGGAC/TTAATT 1 -- us2k10--------
    rs10097311,2
    C,F--40837969(-) CCCTGT/ACTCAa 1 -- us2k11Minor allele frequency- A:0.04NA 120
    rs1120551,2
    C,F,A--40838065(-) atgccA/Ggagcc 1 -- us2k110Minor allele frequency- G:0.37NA WA CSA EA 372

    HapMap Linkage Disequilibrium report for SMAP2 (40810522 - 40888998 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SMAP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv870632CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SMAP2
    DNA2.0 Custom Variant and Variant Library Synthesis for SMAP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SMAP2 for disorders           About MalaCards
    OMIM gene information: 607223    OMIM disorders: --


    SMAP2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SMAP2
    Human Genome Epidemiology (HuGE) Navigator: SMAP2 (5 documents)

    Export disorders for SMAP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SMAP2 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with SMAP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Putative association of SMAPIL polymorphisms with ris k of aspirin intolerance in asthmatics. (PubMed id 20831471)1, 4 Kim J.Y....Shin H.D. (2010)
    2. SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network. (PubMed id 16571680)1, 3 Natsume W....Satake M. (2006)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. The carboxy-terminal region of SMAP2 directs subcellu lar localization as well as Arf protein specificity. (PubMed id 21147065)1 Sakakura I....Watanabe T. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    10. Proteomic analysis of integrin-associated complexes i dentifies RCC2 as a dual regulator of Rac1 and Arf6. (PubMed id 19738201)1 Humphries J.D....Humphries M.J. (2009)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64744 HGNC: 25082 AceView: LOC64744 Ensembl:ENSG00000084070 euGenes: HUgn64744
    ECgene: SMAP2 Kegg: 64744 H-InvDB: SMAP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SMAP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SMAP2 gene:
    Search GeneIP for patents involving SMAP2

    GeneCards and IP:
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