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Aliases for SMAD5-AS1 Gene

Subcategory (RNA class) for SMAD5-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for SMAD5-AS1 Gene

  • SMAD5 Antisense RNA 1 2 3 4 5
  • SMAD5 Antisense RNA 1 (Non-Protein Coding) 2 3
  • SMAD Family Member 5 Opposite Strand 2 3
  • SMAD5OS 3 4
  • DAMS 3 4
  • 10.3 KDa Proline-Rich Protein DAMS 4
  • SMAD In The Antisense Orientation 3
  • SMAD Family Member 5, Antisense 3
  • SMAD5 Opposite Strand Protein 4
  • SMAD5AS 3

External Ids for SMAD5-AS1 Gene

Previous HGNC Symbols for SMAD5-AS1 Gene

  • SMAD5OS

Previous GeneCards Identifiers for SMAD5-AS1 Gene

  • GC05M135465

Summaries for SMAD5-AS1 Gene

GeneCards Summary for SMAD5-AS1 Gene

SMAD5-AS1 (SMAD5 Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with SMAD5-AS1 include Alternating Hemiplegia Of Childhood.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SMAD5-AS1 Gene

Genomics for SMAD5-AS1 Gene

Regulatory Elements for SMAD5-AS1 Gene

Enhancers for SMAD5-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F136108 0.7 ENCODE 11.5 +26.6 26604 0.2 IKZF1 EED JUNB EBF1 RELA SMAD5 SMAD5-AS1 LOC389332 ENSG00000277859 ENSG00000278815 VTRNA2-1
GH05F136159 0.2 ENCODE 11.3 -24.8 -24753 0.9 FOSL1 ZNF766 LOC389332 SMAD5-AS1 SMAD5 GC05M136134
GH05F136104 0.8 Ensembl ENCODE 11.1 +30.4 30357 1.0 GATA3 NR2F2 SMAD5 SMAD5-AS1 ENSG00000254239 IL9 LOC389332 VTRNA2-1 ENSG00000277859 ENSG00000278815
GH05F136087 0.8 Ensembl ENCODE 10.5 +46.3 46267 3.0 HDAC1 PKNOX1 ZNF766 GATA2 FOS CREM EGR2 ZEB2 REST NR2F2 SMAD5 SMAD5-AS1 LECT2 ENSG00000254239 IL9 ENSG00000278815 VTRNA2-1 ENSG00000277859
GH05F136086 0.8 ENCODE 10.5 +47.9 47924 0.2 SMAD5 SMAD5-AS1 LECT2 IL9 ENSG00000254239 ENSG00000278815 VTRNA2-1 ENSG00000277859
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around SMAD5-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for SMAD5-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001290955 1290 2401 PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF143 ZNF207

Genomic Location for SMAD5-AS1 Gene

Chromosome:
5
Start:
136,129,507 bp from pter
End:
136,134,890 bp from pter
Size:
5,384 bases
Orientation:
Minus strand

Genomic View for SMAD5-AS1 Gene

Genes around SMAD5-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SMAD5-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SMAD5-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SMAD5-AS1 Gene

Proteins for SMAD5-AS1 Gene

  • Protein details for SMAD5-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y6J3-SMA5O_HUMAN
    Recommended name:
    SMAD5 antisense gene protein 1
    Protein Accession:
    Q9Y6J3

    Protein attributes for SMAD5-AS1 Gene

    Size:
    95 amino acids
    Molecular mass:
    10312 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This protein is coded from a SMAD5 gene antisense transcript.

neXtProt entry for SMAD5-AS1 Gene

Post-translational modifications for SMAD5-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SMAD5-AS1 Gene

Domains & Families for SMAD5-AS1 Gene

Protein Domains for SMAD5-AS1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for SMAD5-AS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with SMAD5-AS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SMAD5-AS1 Gene

Function for SMAD5-AS1 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SMAD5-AS1 Gene

Localization for SMAD5-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SMAD5-AS1 Gene

Pathways & Interactions for SMAD5-AS1 Gene

SuperPathways for SMAD5-AS1 Gene

No Data Available

Interacting Proteins for SMAD5-AS1 Gene

Gene Ontology (GO) - Biological Process for SMAD5-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction TAS 10049768
genes like me logo Genes that share ontologies with SMAD5-AS1: view

No data available for Pathways by source and SIGNOR curated interactions for SMAD5-AS1 Gene

Transcripts for SMAD5-AS1 Gene

mRNA/cDNA for SMAD5-AS1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SMAD5-AS1 Gene

SMAD5 antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SMAD5-AS1 Gene

No ASD Table

Relevant External Links for SMAD5-AS1 Gene

GeneLoc Exon Structure for
SMAD5-AS1
ECgene alternative splicing isoforms for
SMAD5-AS1

Expression for SMAD5-AS1 Gene

mRNA expression in normal human tissues for SMAD5-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for SMAD5-AS1 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x11.8) and Skin - Sun Exposed (Lower leg) (x8.4).

SOURCE GeneReport for Unigene cluster for SMAD5-AS1 Gene:

Hs.59666

mRNA Expression by UniProt/SwissProt for SMAD5-AS1 Gene:

Q9Y6J3-SMA5O_HUMAN
Tissue specificity: Expressed in fetal tissues.
genes like me logo Genes that share expression patterns with SMAD5-AS1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for SMAD5-AS1 Gene

Orthologs for SMAD5-AS1 Gene

Evolution for SMAD5-AS1 Gene

ENSEMBL:
Gene Tree for SMAD5-AS1 (if available)
TreeFam:
Gene Tree for SMAD5-AS1 (if available)

No data available for Orthologs for SMAD5-AS1 Gene

Paralogs for SMAD5-AS1 Gene

No data available for Paralogs for SMAD5-AS1 Gene

Variants for SMAD5-AS1 Gene

Sequence variations from dbSNP and Humsavar for SMAD5-AS1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10085013 -- 136,134,352(+) CAGAG(A/T)GAATT intron-variant, nc-transcript-variant
rs10544057 -- 136,134,051(+) GGGGG(-/GGG)TGTTG intron-variant, nc-transcript-variant
rs10584514 -- 136,134,038(+) GCTTT(-/GGG)GGGGG intron-variant, nc-transcript-variant
rs111326794 -- 136,134,356(+) GTGAA(G/T)TAGTT intron-variant, nc-transcript-variant
rs113053935 -- 136,131,036(+) TCTGG(-/A)AAAAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SMAD5-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2759380 CNV loss 17122850

Relevant External Links for SMAD5-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SMAD5-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SMAD5-AS1 Gene

Disorders for SMAD5-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for SMAD5-AS1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
alternating hemiplegia of childhood
  • ahc
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for SMAD5-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SMAD5-AS1
genes like me logo Genes that share disorders with SMAD5-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for SMAD5-AS1 Gene

Publications for SMAD5-AS1 Gene

  1. An antisense transcript to SMAD5 expressed in fetal and tumor tissues. (PMID: 10049768) Zavadil J. … Nagarajan L. (Biochem. Biophys. Res. Commun. 1999) 2 3 4 64

Products for SMAD5-AS1 Gene

Sources for SMAD5-AS1 Gene

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