SMAD5-AS1 Gene
RNA gene GIFtS: 28
GCID: GC05M135465
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SMAD5 antisense RNA 1(Previous names: SMAD family member 5 opposite strand, SMAD5 antisense RNA...)
(Previous symbol: SMAD5OS)
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Aliases
for SMAD5-AS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 4
| Aliases |
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| SMAD5 Antisense RNA 11 2 3 | | SMAD5 Antisense RNA 1 (Non-Protein Coding)1 | | DAMS1 2 3 | | SMAD5AS2 | | SMAD5OS1 2 3 | | 10.3 KDa Proline-Rich Protein DAMS3 | | SMAD Family Member 5 Opposite Strand1 | | SMAD5 Opposite Strand Protein3 |
| External Ids: | HGNC: 305861 | Entrez Gene: 95972 | Ensembl: ENSG000001646217 | UniProtKB: Q9Y6J33 |
Export aliases for SMAD5-AS1 gene to outside databases
|---|
Summaries
for SMAD5-AS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
fRNAdb sequence ontology for SMAD5-AS1:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
View fRNAdb secondary structures for SMAD5-AS1 |
Genomic Views
for SMAD5-AS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for SMAD5-AS1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SMAD5-AS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMAD5-AS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1SMAD5-AS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M135465: view genomic region
(about GC identifiers)
Start:
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135,465,196 bp from pter |
End:
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135,470,579 bp from pter |
Size:
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5,384 bases |
Orientation:
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minus strand |
ORGUL member locations:
Legend (see complete legend)
- n332936
- n377646
- FR0321513
- FR0407703
135465187 135467883 135470579 chr5
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Proteins
for SMAD5-AS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SMA5O_HUMAN, Q9Y6J3 (See
protein sequence)Recommended Name: SMAD5 antisense gene protein 1 Size: 95 amino acids; 10312 Da
Miscellaneous: This protein is coded from a SMAD5 gene antisense transcriptExplore the universe of human proteins at neXtProt for SMAD5-AS1: NX_Q9Y6J3
SMAD5-AS1 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
SMAD5-AS1 Antibody Products:
Assay Products for SMAD5-AS1: |
Protein
Domains /
Families
for SMAD5-AS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9Y6J3 |
Function
for SMAD5-AS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMAD5-AS1 |
|
Pathways & Interactions
for SMAD5-AS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SMAD5-AS1
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
SMAD5-AS1 for ontologies About GeneDecksing
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Drugs & Compounds
for SMAD5-AS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SMAD5-AS1
Search CenterWatch for drugs/clinical trials and news about SMAD5-AS1 
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Transcripts
for SMAD5-AS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
| 1 fRNAdb Secondary structure:
REFSEQ mRNAs for SMAD5-AS1 gene: NM_022001.1 Unigene Cluster for SMAD5-AS1: SMAD5 antisense RNA 1 Hs.59666 [show with all ESTs]Unigene Representative Sequence: AF0711111 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000297163(uc003lbi.4)
Additional cDNA sequence: AF071111.1 AF086556.1 NR_026763.1 2 DOTS entries: DT.91755468 DT.95356476
GeneLoc Exon Structure
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Expression
for SMAD5-AS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for SMAD5-AS1:H-invDB
SMAD5-AS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACATCAGAG
About this image
Genevestigator expression for SMAD5-AS1
SOURCE GeneReport for Unigene cluster: Hs.59666
UniProtKB/Swiss-Prot: SMA5O_HUMAN, Q9Y6J3Tissue specificity: Expressed in fetal tissues
SABiosciences Custom PCR Arrays for SMAD5-AS1
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SMAD5-AS1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SMAD5-AS1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMAD5-AS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMAD5-AS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMAD5-AS1 |
Orthologs
for SMAD5-AS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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--
ENSEMBL Gene Tree for SMAD5-AS1 (if available)
TreeFam Gene Tree for SMAD5-AS1 (if available) |
Paralogs
for SMAD5-AS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SMAD5-AS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for SMAD5-AS1 (135465196 - 135470579 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SMAD5-AS1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMAD5-AS1 |
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Disorders
/ Diseases
for SMAD5-AS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 SMAD5-AS1 for disorders About MalaCards
SMAD5-AS1 for disorders About GeneDecksing
OMIM gene information: 603110 601888
Export disorders for SMAD5-AS1 gene to outside databases
|
Publications
for SMAD5-AS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for SMAD5-AS1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SMAD5-AS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An antisense transcript to SMAD5 expressed in fetal and tumor tissues. (PubMed id 10049768)1, 2, 3 Zavadil J.... Nagarajan L. (1999)
- (PubMed id 15103394)10
- (PubMed id 18089548)10
- (PubMed id 15608161)10
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External Searches for SMAD5-AS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing SMAD5-AS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing SMAD5-AS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SMAD5-AS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SMAD5-AS1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for SMAD5-AS1 gene:
Search GeneIP for patents involving SMAD5-AS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SMAD5-AS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SMAD5-AS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SMAD5-AS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SMAD5-AS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SMAD5-AS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SMAD5-AS1 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SMAD5-AS1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SMAD5-AS1 |
|  |  |  | | | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat SMAD5-AS1 |
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Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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