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Aliases for SLX1B-SULT1A4 Gene

Subcategory (RNA class) for SLX1B-SULT1A4 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for SLX1B-SULT1A4 Gene

  • SLX1B-SULT1A4 Readthrough (NMD Candidate) 2 3 5

External Ids for SLX1B-SULT1A4 Gene

Previous GeneCards Identifiers for SLX1B-SULT1A4 Gene

  • GC16U901288
  • GC16P029475
  • GC16P029478
  • GC16P029483

Summaries for SLX1B-SULT1A4 Gene

Entrez Gene Summary for SLX1B-SULT1A4 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring SLX1B (SLX1 structure-specific endonuclease subunit homolog B) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) genes on the short arm of chromosome 16. A duplicate read-through locus also exists between the SLX1A and SULT1A3 genes located approximately 730 kb downstream on the same chromosome. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2017]

GeneCards Summary for SLX1B-SULT1A4 Gene

SLX1B-SULT1A4 (SLX1B-SULT1A4 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Among its related pathways are Cytochrome P450 - arranged by substrate type and Sulfation Biotransformation Reaction.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLX1B-SULT1A4 Gene

Genomics for SLX1B-SULT1A4 Gene

Regulatory Elements for SLX1B-SULT1A4 Gene


Promoters for SLX1B-SULT1A4 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000085048 -491 2001

Genomic Location for SLX1B-SULT1A4 Gene

Chromosome:
16
Start:
29,455,091 bp from pter
End:
29,464,980 bp from pter
Size:
9,890 bases
Orientation:
Plus strand

Genomic View for SLX1B-SULT1A4 Gene

Genes around SLX1B-SULT1A4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SLX1B-SULT1A4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SLX1B-SULT1A4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLX1B-SULT1A4 Gene

Proteins for SLX1B-SULT1A4 Gene

Post-translational modifications for SLX1B-SULT1A4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SLX1B-SULT1A4 Gene

Domains & Families for SLX1B-SULT1A4 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for SLX1B-SULT1A4 Gene

Function for SLX1B-SULT1A4 Gene

Phenotypes for SLX1B-SULT1A4 Gene

genes like me logo Genes that share phenotypes with SLX1B-SULT1A4: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for SLX1B-SULT1A4 Gene

Localization for SLX1B-SULT1A4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for SLX1B-SULT1A4 Gene

Pathways & Interactions for SLX1B-SULT1A4 Gene

genes like me logo Genes that share pathways with SLX1B-SULT1A4: view

Pathways by source for SLX1B-SULT1A4 Gene

2 BioSystems pathways for SLX1B-SULT1A4 Gene

Interacting Proteins for SLX1B-SULT1A4 Gene

Gene Ontology (GO) - Biological Process for SLX1B-SULT1A4 Gene

None

No data available for SIGNOR curated interactions for SLX1B-SULT1A4 Gene

Drugs & Compounds for SLX1B-SULT1A4 Gene

No Compound Related Data Available

Transcripts for SLX1B-SULT1A4 Gene

mRNA/cDNA for SLX1B-SULT1A4 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for SLX1B-SULT1A4 Gene

No ASD Table

Relevant External Links for SLX1B-SULT1A4 Gene

GeneLoc Exon Structure for
SLX1B-SULT1A4
ECgene alternative splicing isoforms for
SLX1B-SULT1A4

Expression for SLX1B-SULT1A4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for SLX1B-SULT1A4 Gene

genes like me logo Genes that share expression patterns with SLX1B-SULT1A4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for SLX1B-SULT1A4 Gene

Orthologs for SLX1B-SULT1A4 Gene

Evolution for SLX1B-SULT1A4 Gene

ENSEMBL:
Gene Tree for SLX1B-SULT1A4 (if available)
TreeFam:
Gene Tree for SLX1B-SULT1A4 (if available)

No data available for Orthologs for SLX1B-SULT1A4 Gene

Paralogs for SLX1B-SULT1A4 Gene

No data available for Paralogs for SLX1B-SULT1A4 Gene

Variants for SLX1B-SULT1A4 Gene

Sequence variations from dbSNP and Humsavar for SLX1B-SULT1A4 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1002467103 -- 29,461,304(+) AAAAA(A/G)AAAAA intron-variant
rs1002602928 -- 29,455,497(+) GGTTC(C/T)GCCCC intron-variant, upstream-variant-2KB
rs1004158662 -- 29,462,065(+) ATGAC(A/T)TCCCA intron-variant
rs1019512313 -- 29,462,187(+) CTGAT(G/T)ATCCT intron-variant
rs1026856292 -- 29,461,961(+) GCCGG(A/G)CTCAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLX1B-SULT1A4 Gene

Variant ID Type Subtype PubMed ID
dgv1515e59 CNV duplication 20981092
esv22245 CNV gain 19812545
esv2714183 CNV deletion 23290073
esv2758641 CNV gain 17122850
esv2758642 CNV gain 17122850
esv29892 CNV gain 19812545
esv3333204 CNV duplication 20981092
esv3388213 CNV duplication 20981092
esv3392583 CNV duplication 20981092
esv3406739 CNV duplication 20981092
esv3444439 CNV duplication 20981092
esv3451126 CNV duplication 20981092
nsv1056249 CNV gain 25217958
nsv1078392 CNV duplication 25765185
nsv1078393 CNV duplication 25765185
nsv1139652 CNV duplication 24896259
nsv1141284 CNV duplication 24896259
nsv1146152 CNV duplication 26484159
nsv1148121 CNV duplication 26484159
nsv1150245 CNV duplication 26484159
nsv471388 CNV gain 19718026
nsv471389 CNV gain 19718026
nsv498862 CNV loss 21111241
nsv571809 CNV loss 21841781
nsv571810 CNV loss 21841781
nsv571811 CNV loss 21841781
nsv571819 CNV gain 21841781
nsv820959 CNV duplication 20802225
nsv821543 CNV duplication 20802225
nsv9426 CNV gain 18304495
nsv9431 CNV gain+loss 18304495
nsv953799 CNV deletion 24416366
nsv960011 CNV duplication 23825009
nsv977952 CNV duplication 23825009
nsv977954 CNV duplication 23825009
nsv978130 CNV duplication 23825009

Relevant External Links for SLX1B-SULT1A4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SLX1B-SULT1A4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SLX1B-SULT1A4 Gene

Disorders for SLX1B-SULT1A4 Gene

Relevant External Links for SLX1B-SULT1A4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SLX1B-SULT1A4

No disorders were found for SLX1B-SULT1A4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SLX1B-SULT1A4 Gene

Publications for SLX1B-SULT1A4 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies. (PMID: 15358107) Hildebrandt M.A.T. … Weinshilboum R.M. (Biochem. Biophys. Res. Commun. 2004) 3 64

Products for SLX1B-SULT1A4 Gene

Sources for SLX1B-SULT1A4 Gene

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