Aliases for SLURP1 Gene
External Ids for SLURP1 Gene
Previous GeneCards Identifiers for SLURP1 Gene
The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for SLURP1 Gene
SLURP1 (Secreted LY6/PLAUR Domain Containing 1) is a Protein Coding gene. Diseases associated with SLURP1 include meleda disease and al-raqad syndrome. GO annotations related to this gene include cytokine activity. An important paralog of this gene is LYPD2.
UniProtKB/Swiss-Prot for SLURP1 Gene
Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin.