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Aliases for SLMO1 Gene

Aliases for SLMO1 Gene

  • Slowmo Homolog 1 (Drosophila) 2 3
  • Erythroid Differentiation And Denucleation Factor 1 2 3
  • C18orf43 3 4
  • Chromosome 18 Open Reading Frame 43 2
  • Protein Slowmo Homolog 1 3
  • HFL-EDDG1 3
  • PRELID3A 3

External Ids for SLMO1 Gene

Previous HGNC Symbols for SLMO1 Gene

  • C18orf43

Previous GeneCards Identifiers for SLMO1 Gene

  • GC18P012400
  • GC18P012361

Summaries for SLMO1 Gene

GeneCards Summary for SLMO1 Gene

SLMO1 (Slowmo Homolog 1 (Drosophila)) is a Protein Coding gene. An important paralog of this gene is SLMO2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SLMO1 Gene

Genomics for SLMO1 Gene

Regulatory Elements for SLMO1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SLMO1 Gene

Start:
12,407,896 bp from pter
End:
12,432,238 bp from pter
Size:
24,343 bases
Orientation:
Plus strand

Genomic View for SLMO1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SLMO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SLMO1 Gene

Proteins for SLMO1 Gene

  • Protein details for SLMO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96N28-SLMO1_HUMAN
    Recommended name:
    Protein slowmo homolog 1
    Protein Accession:
    Q96N28
    Secondary Accessions:
    • B0YJ10
    • B4E0C9
    • D3DUJ1
    • Q6AHX2

    Protein attributes for SLMO1 Gene

    Size:
    172 amino acids
    Molecular mass:
    19247 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for SLMO1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for SLMO1 Gene

Proteomics data for SLMO1 Gene at MOPED

Post-translational modifications for SLMO1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for SLMO1 Gene

Domains for SLMO1 Gene

Protein Domains for SLMO1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SLMO1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96N28

UniProtKB/Swiss-Prot:

SLMO1_HUMAN :
  • Q96N28
Domain:
  • Contains 1 PRELI/MSF1 domain.
Family:
  • Belongs to the slowmo family.
genes like me logo Genes that share domains with SLMO1: view

No data available for Gene Families for SLMO1 Gene

Function for SLMO1 Gene

Gene Ontology (GO) - Molecular Function for SLMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1990050 phosphatidic acid transporter activity IBA --
genes like me logo Genes that share ontologies with SLMO1: view

Animal Model Products

CRISPR Products

miRNA for SLMO1 Gene

miRTarBase miRNAs that target SLMO1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLMO1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SLMO1 Gene

Localization for SLMO1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SLMO1 Gene COMPARTMENTS Subcellular localization image for SLMO1 gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2

Gene Ontology (GO) - Cellular Components for SLMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
GO:0005758 mitochondrial intermembrane space IBA --
genes like me logo Genes that share ontologies with SLMO1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SLMO1 Gene

Pathways for SLMO1 Gene

SuperPathways for SLMO1 Gene

No Data Available

Interacting Proteins for SLMO1 Gene

Gene Ontology (GO) - Biological Process for SLMO1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015914 phospholipid transport IBA --
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with SLMO1: view

No data available for Pathways by source for SLMO1 Gene

Transcripts for SLMO1 Gene

Unigene Clusters for SLMO1 Gene

Slowmo homolog 1 (Drosophila):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SLMO1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SLMO1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
SP1: - -
SP2: - - -
SP3: - -
SP4: - - - -
SP5: -

Relevant External Links for SLMO1 Gene

GeneLoc Exon Structure for
SLMO1
ECgene alternative splicing isoforms for
SLMO1

Expression for SLMO1 Gene

mRNA expression in normal human tissues for SLMO1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SLMO1 Gene

SOURCE GeneReport for Unigene cluster for SLMO1 Gene Hs.514718

genes like me logo Genes that share expressions with SLMO1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SLMO1 Gene

Orthologs for SLMO1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SLMO1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SLMO1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SLMO1 35
  • 85.27 (n)
  • 89.53 (a)
SLMO1 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SLMO1 35
  • 84.68 (n)
  • 90.06 (a)
SLMO1 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Slmo1 35
  • 85.27 (n)
  • 90.12 (a)
Slmo1 16
Slmo1 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SLMO1 36
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SLMO1 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Slmo1 35
  • 85.85 (n)
  • 90.12 (a)
chicken
(Gallus gallus)
Aves SLMO1 35
  • 77.03 (n)
  • 87.8 (a)
SLMO1 36
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia slmo1 35
  • 72.87 (n)
  • 83.14 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC563270 35
  • 71.83 (n)
  • 78.57 (a)
slmo1 36
  • 75 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta slmo 36
  • 39 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F15D3.6 36
  • 31 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes UPS2 35
  • 45.33 (n)
  • 35.37 (a)
UPS2 36
  • 26 (a)
ManyToMany
UPS3 36
  • 27 (a)
ManyToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0D18348g 35
  • 48.17 (n)
  • 36.59 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU04307 35
  • 46.06 (n)
  • 32.73 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPBC36.10 35
  • 42.13 (n)
  • 33.74 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.655 36
  • 30 (a)
OneToMany
Species with no ortholog for SLMO1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SLMO1 Gene

ENSEMBL:
Gene Tree for SLMO1 (if available)
TreeFam:
Gene Tree for SLMO1 (if available)

Paralogs for SLMO1 Gene

Paralogs for SLMO1 Gene

Pseudogenes.org Pseudogenes for SLMO1 Gene

genes like me logo Genes that share paralogs with SLMO1: view

Variants for SLMO1 Gene

Sequence variations from dbSNP and Humsavar for SLMO1 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs481029 -- 12,416,185(+) CCACC(A/G)GCAGC intron-variant
rs487139 -- 12,415,886(-) TGTCC(C/T)AAGTG intron-variant
rs487179 -- 12,422,420(+) GTGGC(A/G)TGATC intron-variant
rs500300 -- 12,422,890(+) TGCCA(C/T)GGTTG intron-variant
rs500718 -- 12,413,110(+) ctatt(C/T)tttcc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SLMO1 Gene

Variant ID Type Subtype PubMed ID
nsv909400 CNV Loss 21882294
dgv1012e1 CNV Complex 17122850
nsv909404 CNV Loss 21882294
nsv9610 CNV Gain 18304495
nsv519557 CNV Loss 19592680
nsv130656 CNV Loss 16902084

Relevant External Links for SLMO1 Gene

HapMap Linkage Disequilibrium report
SLMO1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SLMO1 Gene

Disorders for SLMO1 Gene

Relevant External Links for SLMO1

Genetic Association Database (GAD)
SLMO1
Human Genome Epidemiology (HuGE) Navigator
SLMO1
genes like me logo Genes that share disorders with SLMO1: view

No data available for UniProtKB/Swiss-Prot for SLMO1 Gene

Publications for SLMO1 Gene

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. (PMID: 24270810) Hasson S.A. … Youle R.J. (Nature 2013) 3

Products for SLMO1 Gene

Sources for SLMO1 Gene

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