External Ids for SLITRK3 Gene
Previous GeneCards Identifiers for SLITRK3 Gene
Members of the SLITRK family, such as SLITRK3, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK3, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SLITRK3 Gene
SLITRK3 (SLIT And NTRK-Like Family, Member 3) is a Protein Coding gene. An important paralog of this gene is LRRC38.
UniProtKB/Swiss-Prot for SLITRK3 Gene
Suppresses neurite outgrowth.