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SLITRK1 Gene

protein-coding GIFtS: 58
GCID: GC13M084451

SLIT And NTRK-Like Family, Member 1

(Previous name: leucine rich repeat containing 12)
(Previous symbol: LRRC12)

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
SLIT And NTRK-Like Family, Member 1¹ ²		KIAA1910³ ⁵
LRRC12¹ ² ³		Leucine Rich Repeat Containing 12¹
Leucine-Rich Repeat-Containing Protein 12² ³		SLIT And NTRK-Like Protein 1²
TTM² ⁵		Slit And Trk Like Gene 1²

External Ids:	HGNC: 20297¹	Entrez Gene: 114798²	Ensembl: ENSG00000178235⁷	OMIM: 609678⁵	UniProtKB: Q96PX8³

Export aliases for SLITRK1 gene to outside databases

Previous GC identifers: GC13M082251 GC13M082249 GC13M083349 GC13M065151

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SLITRK1 Gene:

This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins

that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares

homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology

to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene

may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants. (provided

by RefSeq, Jul 2013)

GeneCards Summary for SLITRK1 Gene:

SLITRK1 (SLIT and NTRK-like family, member 1) is a protein-coding gene. Diseases associated with SLITRK1 include body dysmorphic disorder, and trichotillomania. An important paralog of this gene is SLITRK5.

UniProtKB/Swiss-Prot: SLIK1_HUMAN, Q96PX8

Function: Enhances neuronal dendrite outgrowth

Gene Wiki entry for SLITRK1 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000013.11 NC_018924.2 NT_024524.15

Regulatory elements:

Regulatory transcription factor binding sites in the SLITRK1 gene promoter:
STAT1 STAT1beta Nkx2-5 CUTL1 STAT1alpha SRY POU2F1 POU2F1a POU2F1c
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SLITRK1 promoter sequence

Search Chromatin IP Primers for SLITRK1

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SLITRK1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q31.1 Ensembl cytogenetic band: 13q31.1 HGNC cytogenetic band: 13q31.1

SLITRK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SLITRK1 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13M084451: view genomic region (about GC identifiers)

Start:	84,451,343 bp from pter	End:	84,456,528 bp from pter
Size:	5,186 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SLIK1_HUMAN, Q96PX8 (See protein sequence)

Recommended Name: SLIT and NTRK-like protein 1 precursor

Size: 696 amino acids; 77735 Da

Developmental stage: At 20 weeks of gestation, expressed in multiple brain regions, including the developing

neo-cortical plate, subplate zone, striatum, globus pallidus, thalamus and subthalamus

Sequence caution: Sequence=BAB67803.1; Type=Erroneous initiation;

Secondary accessions: Q5U5I6 Q96SF9

Explore the universe of human proteins at neXtProt for SLITRK1: NX_Q96PX8

Explore proteomics data for SLITRK1 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See SLITRK1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_001268432.1 NP_443142.1

ENSEMBL proteins:

ENSP00000366288

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SLITRK1 Assay Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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4 InterPro protein domains:

IPR000483 Cys-rich_flank_reg_C

IPR001611 Leu-rich_rpt

IPR003591 Leu-rich_rpt_typical-subtyp

IPR000372 LRR-contain_N

Graphical View of Domain Structure for InterPro Entry Q96PX8

ProtoNet protein and cluster: Q96PX8

1 Blocks protein domain: IPB001611 Leucine-rich repeat signature

UniProtKB/Swiss-Prot: SLIK1_HUMAN, Q96PX8

Similarity: Belongs to the SLITRK family

Similarity: Contains 12 LRR (leucine-rich) repeats

Similarity: Contains 2 LRRCT domains

Similarity: Contains 2 LRRNT domains

SLITRK1 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: SLIK1_HUMAN, Q96PX8

Function: Enhances neuronal dendrite outgrowth

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--

SLITRK1 for ontologies About GeneDecksing

Phenotypes:
5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Slitrk1):

behavior/neurological

growth/size/body

homeostasis/metabolism

mortality/aging

nervous system

SLITRK1 for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-outs for SLITRK1: Slitrk1^tm1Lex Slitrk1^tm1Jaru

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SLITRK1

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genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SLITRK1

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		Selected qRT-PCR Assays for microRNAs that regulate SLITRK1 (see all 35):
		hsa-miR-4291 hsa-miR-429 hsa-miR-517a hsa-miR-517c hsa-miR-4275 hsa-miR-570 hsa-miR-532-5p hsa-miR-3148

		SwitchGear 3'UTR luciferase reporter plasmid: SLITRK1 3' UTR sequence

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Gene Editing
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLITRK1

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

SLIK1_HUMAN, Q96PX8: Membrane; Single-pass type I membrane protein (Potential)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
plasma membrane	3
cytosol	1
endoplasmic reticulum	1
extracellular	1
golgi apparatus	1
nucleus	1

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Gene Ontology (GO): 1 cellular component term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral component of membrane	IEA	--

SLITRK1 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for SLITRK1
Interactions:

Search GeneGlobe Interaction Network for SLITRK1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for SLITRK1 (Q96PX8^{2, 3} ENSP00000366288⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946²^,³, ENSP00000300161⁴	MINT-8009119 I2D: score=1 STRING: ENSP00000300161

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Gene Ontology (GO): 5 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007399	nervous system development	--	--
GO:0007409	axonogenesis	IEA	--
GO:0030534	adult behavior	IEA	--
GO:0035264	multicellular organism growth	IEA	--
GO:0042592	homeostatic process	IEA	--

SLITRK1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for SLITRK1 (SLIK1)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for SLITRK1 gene (2 alternative transcripts):

NM_001281503.1 NM_052910.2

Unigene Cluster for SLITRK1:

SLIT and NTRK-like family, member 1

Hs.415478 [show with all ESTs]

Unigene Representative Sequence: NM_052910

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000377084(uc001vlk.3)

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		Selected qRT-PCR Assays for microRNAs that regulate SLITRK1 (see all 35):
		hsa-miR-4291 hsa-miR-429 hsa-miR-517a hsa-miR-517c hsa-miR-4275 hsa-miR-570 hsa-miR-532-5p hsa-miR-3148

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		QuantiFast Probe-based Assays in human, mouse, rat SLITRK1

Additional mRNA sequence:

AB067497.1 AK299479.1 AY358289.1 BC051738.1

1 DOTS entry:

DT.91649135

Selected AceView cDNA sequences (see all 26):

NM_052910 BC051738 AY358289 AB067497 Z45152 T31600 F10062 Z40879

BF439516 AA677641 BX496202 H08054 BX091443 BF932057 AI500170 F12440

AI565671 AW962553 BI546610 T82468 Z42346 R35384 T73996 H08053

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SLITRK1 expression in normal human tissues (normalized intensities) SLITRK1 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: ACCAATTAAT

About this image

SLITRK1 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 6) fully expand


Brain (Nervous System) fully expand to see all 3 entries
Cerebral Cortex

Bone (Muscoskeletal System) fully expand to see all 2 entries
HyStem+BMP4-induced SK11 cells

Cartilage (Muscoskeletal System) fully expand to see all 2 entries
HyStem+BMP4-induced SM30 cells

Ovary (Reproductive System)
Oviduct

Adipose (Muscoskeletal System)
HyStem+BMP4-induced SM30 cells

SLITRK1 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

SLITRK1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.415478

UniProtKB/Swiss-Prot: SLIK1_HUMAN, Q96PX8

Tissue specificity: Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also

expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas

and primitive neuroectodermal tumors

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SLITRK1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for SLITRK1 gene from Selected species (see all 14) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Slitrk1^{1 , 5}	SLIT and NTRK-like family, member 1^{1, 5}	92.91(n)¹ 97.56(a)¹		14 (56.78 cM)⁵ 76965¹ NM_199065.2¹ NP_951020.1¹ 108909991⁵
chicken (Gallus gallus)	Aves	SLITRK1¹	SLIT and NTRK-like family, member 1	81.36(n) 89.31(a)		418798 XM_416993.4 XP_416993.2
lizard (Anolis carolinensis)	Reptilia	SLITRK1⁶	SLIT and NTRK-like family, member 1	85(a)	1 ↔ 1	3(93916936-93919041)
tropical clawed frog (Xenopus tropicalis)	Amphibia	slitrk1¹	SLIT and NTRK-like family, member 1	74.92(n) 83.88(a)		100124997 NM_001102925.1 NP_001096395.1
zebrafish (Danio rerio)	Actinopterygii	LOC558743¹	SLIT and NTRK-like protein 1-like	69(n) 72.59(a)		558743 XM_005174629.1 XP_005174686.1
fruit fly (Drosophila melanogaster)	Insecta	sli⁶	slit	10(a)	1 → many	2R(11757559-11809623)
worm (Caenorhabditis elegans)	Secernentea	slt-1⁶	Protein SLT-1 (slt-1) mRNA, complete cds	10(a)	1 → many	X(14674319-14683326) WBGene00004854

ENSEMBL Gene Tree for SLITRK1 (if available)
TreeFam Gene Tree for SLITRK1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for SLITRK1 gene

SLITRK5² ISLR² SLIT1² SLIT3² SLITRK6² LRRC38² SLIT2² LRRC26²

SLITRK4² LRTM1² LRRC52² LRRC17² SLITRK2² LRTM2² SLITRK3² LRRC55²

ISLR2² LRRC24²

6 SIMAP similar genes for SLITRK1 using alignment to 1 protein entry: SLIK1_HUMAN:

DKFZp451E1911 SLITRK2 SLITRK4 SLITRK3 SLITRK5 SLITRK6

SLITRK1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191284403^1,2	C	pathogenic¹	65351172(+)	`CCTACC/TGATCA`	1	--	ut3¹		0	--	--	--	--
rs186001100^1,2		--	65349212(+)	`TTTTCA/CATTAA`	1	--	ds500¹		0	--	--	--	--
rs17077405^1,2	C,F,H	--	65349254(+)	`CTTCTA/GTGAGA`	1	--	ds500¹		10		NA NS CSA WA	1052
rs188900773^1,2		--	65349335(+)	`TGCCAA/TTAAAT`	1	--	ds500¹		0	--	--	--	--
rs41561712^1,2	C,F	--	65349344(-)	`GAAGGT/CGACAT`	1	--	ds500¹		6		EU NA EA	426
rs148583148^1,2		--	65349395(+)	`CTTTCC/TAAAGG`	1	--	ds500¹		0	--	--	--	--
rs145590089^1,2		--	65349487(+)	`AGTTGC/TACTTT`	1	--	ds500¹		0	--	--	--	--
rs147713452^1,2		--	65349630(+)	`AATGAC/TGAATG`	1	--	ds500¹		0	--	--	--	--
rs182027644^1,2		--	65349774(+)	`CTTACA/GACTGC`	1	--	ut3¹		0	--	--	--	--
rs186069029^1,2	C	--	65349786(+)	`CTGAGA/GTCTTT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SLITRK1 (84451343 - 84456528 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for SLITRK1: --
Human Gene Mutation Database (HGMD): SLITRK1

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing SLITRK1

DNA2.0 Custom Variant and Variant Library Synthesis for SLITRK1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 609678
OMIM disorders: 137580 613229
UniProtKB/Swiss-Prot: SLIK1_HUMAN, Q96PX8

Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor

and vocal tics and associated with behavioral abnormalities. Note=The disease may be caused by mutations

affecting the gene represented in this entry

Trichotillomania (TTM) [MIM:613229]: A neuropsychiatric disorder characterized by chronic, repetitive, or

compulsive hair pulling resulting in noticeable hair loss. Affected individuals may develop physical

complications and often have overlapping psychological disorders, such as Gilles de la Tourette syndrome or

obsessive-compulsive disorder. Note=The disease may be caused by mutations affecting the gene represented in this

entry

18 diseases for SLITRK1: About MalaCards

body dysmorphic disorder trichotillomania gilles de la tourette syndrome neurotic excoriation

stereotypic movement disorder wilson disease ganglioglioma obsessive-compulsive disorder

primitive neuroectodermal tumor oligodendroglioma myotonic dystrophy astrocytoma

tonsillitis bipolar disorder cerebritis multiple myeloma

myeloma neuronitis

7 diseases from the University of Copenhagen DISEASES database for SLITRK1:

Trichotillomania Gilles de la Tourette syndrome Stereotypic movement disorder Wilson disease

Body dysmorphic disorder Neurotic excoriation Kleptomania

SLITRK1 for disorders About GeneDecksing

Genetic Association Database (GAD): SLITRK1
Human Genome Epidemiology (HuGE) Navigator: SLITRK1 (7 documents)

Export disorders for SLITRK1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for SLITRK1 gene, integrated from 10 sources (see all 30):
(articles sorted by number of sources associating them with SLITRK1)

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Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue. (PubMed id 14557068)^{1, 2, 3, 9} Aruga J.... Mikoshiba K. (Gene 2003)
Sequence variants in SLITRK1 are associated with Tourette's syndrome. (PubMed id 16224024)^{1, 2, 4} Abelson J.F.... State M.W. (Science 2005)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2, 3} Clark H.F.... Gray A.M. (Genome Res. 2003)
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)^{1, 4} Trynka G....Wijmenga C. (Gut 2009)
Association study between Gilles de la Tourette Syndrome and two genes in the Robo-Slit pathway located in the chromosome 11q24 linked/associated region. (PubMed id 17671968)^{1, 4} Miranda D.M....Barr C.L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
Sequence analysis of the complete SLITRK1 gene in Austrian patients with Tourette's disorder. (PubMed id 19018236)^{1, 4} Zimprich A....Stamenkovic M. (Psychiatr. Genet. 2008)
Examination of the SLITRK1 gene in Caucasian patients with Tourette syndrome. (PubMed id 17083340)^{1, 4} Deng H....Jankovic J. (Acta Neurol. Scand. 2006)
Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. (PubMed id 17035247)^{1, 4} Keen-Kim D....Freimer N.B. (Hum. Mol. Genet. 2006)
The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)^{1, 2} Dunham A.... Ross M.T. (Nature 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 114798	HGNC: 20297	AceView: SLITRK1	Ensembl:ENSG00000178235	euGenes: HUgn114798
ECgene: SLITRK1	H-InvDB: SLITRK1

(According to HUGE)
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HUGE: KIAA1910

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SLITRK1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SLITRK1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SLITRK1 gene:
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SLITRK1 Gene

SLIT And NTRK-Like Family, Member 1

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SLITRK1 Gene

SLIT And NTRK-Like Family, Member 1

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